α1-Adrenoceptor subclassification in vascular smooth muscle

N. A. Flavahan; P. M. Vanhoutte

doi:10.1016/0165-6147(86)90383-4

α₁-Adrenoceptor subclassification in vascular smooth muscle

N. A. Flavahan, P. M. Vanhoutte

Research output: Contribution to journal › Article › peer-review

197 Scopus citations

Abstract

Affinity studies indicate that there appears to be two subtypes of α₁-adrenoceptors in the vascular smooth muscle of blood vessels from rodents and rabbit. Nichlas Flavahan and Paul Vanhoutte analyse data from the literature which supports the existence of one subtype with high affinity for prazosin and yohimbine and a second subtype with low affinity for these antagonists.

Original language	English (US)
Pages (from-to)	347-349
Number of pages	3
Journal	Trends in Pharmacological Sciences
Volume	7
Issue number	C
DOIs	https://doi.org/10.1016/0165-6147(86)90383-4
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Toxicology
Pharmacology

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10.1016/0165-6147(86)90383-4

Cite this

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title = "α1-Adrenoceptor subclassification in vascular smooth muscle",

abstract = "Affinity studies indicate that there appears to be two subtypes of α1-adrenoceptors in the vascular smooth muscle of blood vessels from rodents and rabbit. Nichlas Flavahan and Paul Vanhoutte analyse data from the literature which supports the existence of one subtype with high affinity for prazosin and yohimbine and a second subtype with low affinity for these antagonists.",

author = "Flavahan, {N. A.} and Vanhoutte, {P. M.}",

year = "1986",

doi = "10.1016/0165-6147(86)90383-4",

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T1 - α1-Adrenoceptor subclassification in vascular smooth muscle

AU - Flavahan, N. A.

AU - Vanhoutte, P. M.

PY - 1986

Y1 - 1986

N2 - Affinity studies indicate that there appears to be two subtypes of α1-adrenoceptors in the vascular smooth muscle of blood vessels from rodents and rabbit. Nichlas Flavahan and Paul Vanhoutte analyse data from the literature which supports the existence of one subtype with high affinity for prazosin and yohimbine and a second subtype with low affinity for these antagonists.

AB - Affinity studies indicate that there appears to be two subtypes of α1-adrenoceptors in the vascular smooth muscle of blood vessels from rodents and rabbit. Nichlas Flavahan and Paul Vanhoutte analyse data from the literature which supports the existence of one subtype with high affinity for prazosin and yohimbine and a second subtype with low affinity for these antagonists.

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U2 - 10.1016/0165-6147(86)90383-4

DO - 10.1016/0165-6147(86)90383-4

M3 - Article

AN - SCOPUS:0022947140

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JO - Trends in Pharmacological Sciences

JF - Trends in Pharmacological Sciences

IS - C

ER -

α₁-Adrenoceptor subclassification in vascular smooth muscle

Abstract

ASJC Scopus subject areas

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