Abstract
Xenopus oocyte expression of the recently cloned γ-aminobutyric acid (GABA)(ρ1) receptor subunit cDNA yields a pharmacologic profile characteristic of the GABA(c) responses described by Johnston [Benzodiazepine/GABA Receptors and Chloride Channels. Receptor Biochemistry and Methodology (R. W. Olsen and J. C. Venter, eds.), Vol. 5. Alan R. Liss, New York, 57-71 (1986)] and the responses to retinal mRNA recently reported in the Xenopus expression system [Proc. Natl. Acad. Sci. USA 88:4318-4322 (1991)]. A rationale for defining GABA (ρ1) as forming a GABA(c) receptor is discussed.
Original language | English (US) |
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Pages (from-to) | 683-687 |
Number of pages | 5 |
Journal | Molecular Pharmacology |
Volume | 41 |
Issue number | 4 |
State | Published - Dec 1 1992 |
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology