β-human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization - Embryo transfer patients

Liu Hung-Ching Liu; D. Kreiner; S. J. Muasher; G. Jones; H. Jones; Z. Rosenwaks

doi:10.1016/s0015-0282(16)60014-6

β-human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization - Embryo transfer patients

Liu Hung-Ching Liu, D. Kreiner, S. J. Muasher, G. Jones, H. Jones, Z. Rosenwaks

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Serum human chorionic gonadotropin (hCG) was studied to test its predictability of pregnancy outcome in in vitro fertilization (IVF) patients. The mean ± standard deviation of serum hCG concentration related to the day complete clearance of exogenous hCG was derived from 47 single term pregnancies as a normal range. This range can be used to predict spontaneous abortion (77%), multiple pregnancy (60%), and abortion in multiple-sac pregnancies terminating in the birth of fewer infants than the initial number of sacs (80%). The results also showed that our stimulation protocol did not affect the clearance rate and doubling time of endogenous hCG or implantation time as suggested by the time of endogenous hCG detection and that spontaneous abortion may be due to late implantation.

Original language	English (US)
Pages (from-to)	89-94
Number of pages	6
Journal	Fertility and sterility
Volume	50
Issue number	1
DOIs	https://doi.org/10.1016/s0015-0282(16)60014-6
State	Published - 1988
Externally published	Yes

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

Access to Document

10.1016/s0015-0282(16)60014-6

Cite this

@article{976479712c934855a0f9e5a8ff5b58ae,

title = "β-human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization - Embryo transfer patients",

abstract = "Serum human chorionic gonadotropin (hCG) was studied to test its predictability of pregnancy outcome in in vitro fertilization (IVF) patients. The mean ± standard deviation of serum hCG concentration related to the day complete clearance of exogenous hCG was derived from 47 single term pregnancies as a normal range. This range can be used to predict spontaneous abortion (77%), multiple pregnancy (60%), and abortion in multiple-sac pregnancies terminating in the birth of fewer infants than the initial number of sacs (80%). The results also showed that our stimulation protocol did not affect the clearance rate and doubling time of endogenous hCG or implantation time as suggested by the time of endogenous hCG detection and that spontaneous abortion may be due to late implantation.",

author = "{Hung-Ching Liu}, Liu and D. Kreiner and Muasher, {S. J.} and G. Jones and H. Jones and Z. Rosenwaks",

year = "1988",

doi = "10.1016/s0015-0282(16)60014-6",

language = "English (US)",

volume = "50",

pages = "89--94",

journal = "Fertility and sterility",

issn = "0015-0282",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - β-human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization - Embryo transfer patients

AU - Hung-Ching Liu, Liu

AU - Kreiner, D.

AU - Muasher, S. J.

AU - Jones, G.

AU - Jones, H.

AU - Rosenwaks, Z.

PY - 1988

Y1 - 1988

N2 - Serum human chorionic gonadotropin (hCG) was studied to test its predictability of pregnancy outcome in in vitro fertilization (IVF) patients. The mean ± standard deviation of serum hCG concentration related to the day complete clearance of exogenous hCG was derived from 47 single term pregnancies as a normal range. This range can be used to predict spontaneous abortion (77%), multiple pregnancy (60%), and abortion in multiple-sac pregnancies terminating in the birth of fewer infants than the initial number of sacs (80%). The results also showed that our stimulation protocol did not affect the clearance rate and doubling time of endogenous hCG or implantation time as suggested by the time of endogenous hCG detection and that spontaneous abortion may be due to late implantation.

AB - Serum human chorionic gonadotropin (hCG) was studied to test its predictability of pregnancy outcome in in vitro fertilization (IVF) patients. The mean ± standard deviation of serum hCG concentration related to the day complete clearance of exogenous hCG was derived from 47 single term pregnancies as a normal range. This range can be used to predict spontaneous abortion (77%), multiple pregnancy (60%), and abortion in multiple-sac pregnancies terminating in the birth of fewer infants than the initial number of sacs (80%). The results also showed that our stimulation protocol did not affect the clearance rate and doubling time of endogenous hCG or implantation time as suggested by the time of endogenous hCG detection and that spontaneous abortion may be due to late implantation.

UR - http://www.scopus.com/inward/record.url?scp=0023707210&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023707210&partnerID=8YFLogxK

U2 - 10.1016/s0015-0282(16)60014-6

DO - 10.1016/s0015-0282(16)60014-6

M3 - Article

C2 - 3384122

AN - SCOPUS:0023707210

SN - 0015-0282

VL - 50

SP - 89

EP - 94

JO - Fertility and sterility

JF - Fertility and sterility

IS - 1

ER -

β-human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization - Embryo transfer patients

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this