Zheng Han

Research Associate

20152019
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Research Output 2015 2019

2019

Carbon Dots as a New Class of Diamagnetic Chemical Exchange Saturation Transfer (diaCEST) MRI Contrast Agents

Zhang, J., Yuan, Y., Gao, M., Han, Z., Chu, C., Li, Y., Van Zijl, P. C., Ying, M., Bulte, J. W. & Liu, G., Jan 1 2019, In : Angewandte Chemie - International Edition.

Research output: Contribution to journalArticle

Magnetic resonance imaging
Contrast Media
Carbon
Magnetic resonance
Imaging techniques
Phosphatases
Magnetic resonance
Acid Phosphatase
Phenol
Contrast Media

Extradomain-B Fibronectin-Targeted Dextran-Based Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Probe for Detecting Pancreatic Cancer

Han, Z., Zhang, S., Fujiwara, K., Zhang, J., Li, Y., Liu, J., Van Zijl, P. C., Lu, Z. R., Zheng, L. & Liu, G., Jan 1 2019, In : Bioconjugate Chemistry.

Research output: Contribution to journalArticle

Dextran
Dextrans
Pancreatic Neoplasms
Fibronectins
Magnetic Resonance Imaging

Molecular imaging of deoxycytidine kinase activity using deoxycytidine-enhanced CEST MRI

Han, Z., Li, Y., Zhang, J., Liu, J., Chen, C., Van Zijl, P. C. & Liu, G., Jan 1 2019, In : Cancer Research. 79, 10, p. 2775-2783 9 p.

Research output: Contribution to journalArticle

Deoxycytidine Kinase
Deoxycytidine
Molecular Imaging
gemcitabine
Neoplasms

Preparation and Evaluation of ZD2 Peptide 64 Cu-DOTA Conjugate as a Positron Emission Tomography Probe for Detection and Characterization of Prostate Cancer

Han, Z., Sergeeva, O., Roelle, S., Cheng, H., Gao, S., Li, Y., Lee, Z. & Lu, Z. R., Jan 14 2019, In : ACS Omega. 4, 1, p. 1185-1190 6 p.

Research output: Contribution to journalArticle

Open Access
Positron emission tomography
Peptides
Tumors
Fibronectins
Molecular imaging
Neuroimaging
Amides
Protons
Water
Brain
Biopolymers
Molecular Imaging
Magnetic resonance
Sugars
Magnetic Resonance Imaging

Synthesis and Evaluation of pH-Sensitive Multifunctional Lipids for Efficient Delivery of CRISPR/Cas9 in Gene Editing

Sun, D., Sun, Z., Jiang, H., Vaidya, A. M., Xin, R., Ayat, N. R., Schilb, A. L., Qiao, P. L., Han, Z., Naderi, A. & Lu, Z. R., Mar 20 2019, In : Bioconjugate Chemistry. 30, 3, p. 667-678 12 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Lipids
Genes
Nanoparticles
Hemolysis
2018

CEST MRI of sepsis-induced acute kidney injury

Liu, J., Han, Z., Chen, G., Li, Y., Zhang, J., Xu, J., Van Zijl, P. C., Zhang, S. & Liu, G., Aug 1 2018, In : NMR in Biomedicine. 31, 8, e3942.

Research output: Contribution to journalArticle

Acute Kidney Injury
Magnetic resonance imaging
Sepsis
Kidney
Lipopolysaccharides

Erratum: Author Correction: Targeted gadofullerene for sensitive magnetic resonance imaging and risk-stratification of breast cancer (Nature communications (2017) 8 1 (692))

Han, Z., Wu, X., Roelle, S., Chen, C., Schiemann, W. P. & Lu, Z. R., Jan 8 2018, In : Nature communications. 9, 1, 1 p.

Research output: Contribution to journalComment/debate

Open Access
document markup languages
HTML
sentences
Optical Imaging
Magnetic resonance

Magnetic resonance molecular imaging of metastatic breast cancer by targeting extradomain-B fibronectin in the tumor microenvironment

Han, Z., Cheng, H., Parvani, J. G., Zhou, Z. & Lu, Z. R., Jun 1 2018, In : Magnetic resonance in medicine. 79, 6, p. 3135-3143 9 p.

Research output: Contribution to journalArticle

Molecular Imaging
Tumor Microenvironment
Fibronectins
Magnetic Resonance Imaging
Breast Neoplasms

Triazoles as T2-Exchange Magnetic Resonance Imaging Contrast Agents for the Detection of Nitrilase Activity

Zhang, J., Han, Z., Lu, J., Li, Y., Liao, X., Van Zijl, P. C., Yang, X. & Liu, G., Jan 1 2018, (Accepted/In press) In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

nitrilase
Triazoles
Contrast Media
Protons
Magnetic resonance
2017

Characterization of tumor vascular permeability using natural dextrans and CEST MRI

Li, Y., Qiao, Y., Chen, H., Bai, R., Staedtke, V., Han, Z., Xu, J., Chan, K. W. Y., Yadav, N., Bulte, J. W., Zhou, S., Van Zijl, P. C. & Liu, G., Jan 1 2017, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Capillary Permeability
Dextrans
Neoplasms
Injections
Permeability

Synthesis and Assessment of Peptide Gd-DOTA Conjugates Targeting Extradomain B Fibronectin for Magnetic Resonance Molecular Imaging of Prostate Cancer

Li, Y., Han, Z., Roelle, S., DeSanto, A., Sabatelle, R., Schur, R. & Lu, Z. R., Nov 6 2017, In : Molecular Pharmaceutics. 14, 11, p. 3906-3915 10 p.

Research output: Contribution to journalArticle

Molecular Imaging
Fibronectins
Prostatic Neoplasms
Magnetic Resonance Imaging
Peptides

Targeted Contrast Agent Specific to an Oncoprotein in Tumor Microenvironment with the Potential for Detection and Risk Stratification of Prostate Cancer with MRI

Han, Z., Li, Y., Roelle, S., Zhou, Z., Liu, Y., Sabatelle, R., Desanto, A., Yu, X., Zhu, H., Magi-Galluzzi, C. & Lu, Z. R., Apr 19 2017, In : Bioconjugate Chemistry. 28, 4, p. 1031-1040 10 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Oncogene Proteins
Magnetic resonance imaging
Contrast Media
Tumors

Targeted gadofullerene for sensitive magnetic resonance imaging and risk-stratification of breast cancer

Han, Z., Wu, X., Roelle, S., Chen, C., Schiemann, W. P. & Lu, Z. R., Dec 1 2017, In : Nature communications. 8, 1, 692.

Research output: Contribution to journalArticle

Open Access
Magnetic resonance
stratification
breast
magnetic resonance
Tumors

Targeting fibronectin for cancer imaging and therapy

Han, Z. & Lu, Z. R., Jan 1 2017, In : Journal of Materials Chemistry B. 5, 4, p. 639-654 16 p.

Research output: Contribution to journalReview article

Fibronectins
Imaging techniques
Tumors
Cells
Nuclear medicine
2016

A targeted nanoglobular contrast agent from host-guest self-assembly for MR cancer molecular imaging

Zhou, Z., Han, Z. & Lu, Z. R., Apr 1 2016, In : Biomaterials. 85, p. 168-179 12 p.

Research output: Contribution to journalArticle

Molecular imaging
Molecular Imaging
Self assembly
Contrast Media
Tumors
Arsenic
Silicon Dioxide
Silica
Nanoparticles
Pharmaceutical Preparations
2015

EDB fibronectin specific peptide for prostate cancer targeting

Han, Z., Zhou, Z., Shi, X., Wang, J., Wu, X., Sun, D., Chen, Y., Zhu, H., Magi-Galluzzi, C. & Lu, Z. R., May 20 2015, In : Bioconjugate Chemistry. 26, 5, p. 830-838 9 p.

Research output: Contribution to journalArticle

Fibronectins
Peptides
Molecular imaging
Tumors
Prostatic Neoplasms

MRI detection of breast cancer micrometastases with a fibronectin-targeting contrast agent

Zhou, Z., Qutaish, M., Han, Z., Schur, R. M., Liu, Y., Wilson, D. L. & Lu, Z. R., Aug 12 2015, In : Nature communications. 6, 7984.

Research output: Contribution to journalArticle

Open Access
Neoplasm Micrometastasis
Magnetic resonance
Fibronectins
breast
Contrast Media