Yuejin Wu

Assistant Professor

19972019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1997 2019

Filter
Article
2019

Myocardial death and dysfunction after ischemia-reperfusion injury require CaMKIIδ oxidation

Wu, Y., Wang, Q., Feng, N., Granger, J. M. & Anderson, M., Dec 1 2019, In : Scientific reports. 9, 1, 9291.

Research output: Contribution to journalArticle

Open Access
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Reperfusion Injury
Reactive Oxygen Species
Methionine
KATP Channels
2016

A Single Protein Kinase A or Calmodulin Kinase II Site Does Not Control the Cardiac Pacemaker Ca2+ Clock

Wu, Y., Valdivia, H. H., Wehrens, X. H. T. & Anderson, M., Feb 1 2016, In : Circulation: Arrhythmia and Electrophysiology. 9, 2, e003180.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Sarcoplasmic Reticulum
Cyclic AMP-Dependent Protein Kinases
Heart Rate
Isoproterenol
2015

Erratum: The mitochondrial uniporter controls fight or flight heart rate increases (Nature Communications (2015) 6 (6081)) doi: 10.1038/ncomms7081)

Wu, Y., Rasmussen, T. P., Koval, O. M., Joiner, M. L. A., Hall, D. D., Chen, B., Luczak, E. D., Wang, Q., Rokita, A. G., Wehrens, X. H. T., Song, L. S. & Anderson, M. E., Jun 3 2015, In : Nature Communications. 6, 7241.

Research output: Contribution to journalArticle

Erratum: Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels (Nature Cell Biology (2000) 2 (173-177))

Dzhura, I., Wu, Y., Colbran, R. J., Balser, J. R. & Anderson, M. E., Apr 30 2015, In : Nature Cell Biology. 17, 4, p. 530 1 p.

Research output: Contribution to journalArticle

L-Type Calcium Channels
Calcium-Calmodulin-Dependent Protein Kinases
Cell Biology
Calcium

Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart

Rasmussen, T. P., Wu, Y., Joiner, M. L. A., Koval, O. M., Wilson, N. R., Luczak, E., Wang, Q., Chen, B., Gao, Z., Zhu, Z., Wagnerd, B. A., Soto, J., McCormick, M. L., Kutschke, W., Weiss, R. M., Yu, L., Boudreau, R. L., Abel, E. D., Zhan, F., Spitz, D. R. & 4 others, Buettner, G. R., Song, L. S., Zingmanb, L. V. & Anderson, M., Jul 21 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 29, p. 9129-9134 6 p.

Research output: Contribution to journalArticle

Physiological Stress
Homeostasis
Reperfusion Injury
Reactive Oxygen Species
Mitochondrial Membrane Potential

Retraction Notice To: L-Type Ca2+ Channel Facilitation Mediated by Phosphorylation of the β Subunit by CaMKII [Molecular Cell 23 (2006) 641-650]

Grueter, C. E., Abiria, S. A., Dzhura, I., Wu, Y., Ham, A. J. L., Mohler, P. J., Anderson, M. E. & Colbran, R. J., Apr 16 2015, In : Molecular Cell. 58, 2, p. 388 1 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Phosphorylation

The mitochondrial uniporter controls fight or flight heart rate increases

Wu, Y., Rasmussen, T. P., Koval, O. M., Joiner, M. L. A., Hall, D. D., Chen, B., Luczak, E., Wang, Q., Rokita, A. G., Wehrens, X. H. T., Song, L. S. & Anderson, M., Jan 20 2015, In : Nature Communications. 6, 7081.

Research output: Contribution to journalArticle

heart rate
calcium
Heart Rate
flight
Pacemakers
2014

BK channels regulate sinoatrial node firing rate and cardiac pacing in vivo

Lai, M. H., Wu, Y., Gao, Z., Anderson, M., Dalziel, J. E. & Meredith, A. L., Nov 1 2014, In : American Journal of Physiology - Heart and Circulatory Physiology. 307, 9, p. H1327-H1338

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Sinoatrial Node
Heart Rate
Action Potentials
Electrocardiography

CaMKII in sinoatrial node physiology and dysfunction

Wu, Y. & Anderson, M., 2014, In : Frontiers in Pharmacology. 5 MAR, Article 48.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Sinoatrial Node
Ryanodine Receptor Calcium Release Channel
Heart Rate
Calcium-Calmodulin-Dependent Protein Kinases

Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival

Hall, D. D., Wu, Y., Domann, F. E., Spitz, D. R. & Anderson, M., May 6 2014, In : PLoS One. 9, 5, e96866.

Research output: Contribution to journalArticle

breast neoplasms
cell viability
Cell Survival
Cells
Breast Neoplasms

Sarcolemmal ATP-sensitive potassium channels modulate skeletal muscle function under low-intensity workloads

Zhu, Z., Sierra, A., Burnett, C. M. L., Chen, B., Subbotina, E., Koganti, S. R. K., Gao, Z., Wu, Y., Anderson, M., Song, L. S., Goldhamer, D. J., Coetzee, W. A., Hodgson-Zingman, D. M. & Zingman, L. V., Jan 2014, In : Journal of General Physiology. 143, 1, p. 119-134 16 p.

Research output: Contribution to journalArticle

KATP Channels
Workload
Skeletal Muscle
Thermogenesis
Action Potentials
2013

Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate

Gao, Z., Rasmussen, T. P., Li, Y., Kutschke, W., Koval, O. M., Wu, Y., Wu, Y., Hall, D. D., Joiner, M. L. A., Wu, X. Q., Swaminathan, P. D., Purohit, A., Zimmerman, K., Weiss, R. M., Philipson, K. D., Song, L. S., Hund, T. J. & Anderson, M., Jan 18 2013, In : Circulation Research. 112, 2, p. 309-317 9 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Heart Rate
ivabradine
Isoproterenol
Knockout Mice
2011

Catecholamine-independent heart rate increases require Ca 2+/calmodulin-dependent protein kinase II

Gao, Z., Singh, M. V., Hall, D. D., Koval, O. M., Luczak, E., Joiner, M. L. A., Chen, B., Wu, Y., Chaudhary, A. K., Martins, J. B., Hund, T. J., Mohler, P. J., Song, L. S. & Anderson, M., Jun 2011, In : Circulation: Arrhythmia and Electrophysiology. 4, 3, p. 379-387 9 p.

Research output: Contribution to journalArticle

3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Calcium-Calmodulin-Dependent Protein Kinases
Catecholamines
Heart Rate
2010

CaV1.2 β-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations

Koval, O. M., Guan, X., Wu, Y., Joiner, M. L., Gao, Z., Chen, B., Grumbach, I. M., Luczak, E., Colbran, R. J., Song, L. S., Hund, T. J., Mohler, P. J. & Anderson, M., Mar 16 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 11, p. 4996-5000 5 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Cardiac Myocytes
Ryanodine
Phosphorylation
Muscle Cells

If and SR Ca2+ release both contribute to pacemaker activity in canine sinoatrial node cells

Gao, Z., Chen, B., Joiner, M. L. A., Wu, Y., Guan, X., Koval, O. M., Chaudhary, A. K., Cunha, S. R., Mohler, P. J., Martins, J. B., Song, L. S. & Anderson, M., Jul 2010, In : Journal of Molecular and Cellular Cardiology. 49, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Sarcoplasmic Reticulum
Canidae
Ryanodine
Isoproterenol
2009

Calmodulin kinase II is required for fight or flight sinoatrial node physiology

Wu, Y., Gao, Z., Chen, B., Koval, O. M., Singh, M. V., Guan, X., Hund, T. J., Kutschke, W., Sarma, S., Grumbach, I. M., Wehrens, X. H. T., Mohler, P. J., Song, L. S. & Anderson, M., Apr 7 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 14, p. 5972-5977 6 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Sinoatrial Node
Protein Kinases
Isoproterenol
Heart Rate

Local control of Ca2+-induced Ca2+ release in mouse sinoatrial node cells

Chen, B., Wu, Y., Mohler, P. J., Anderson, M. & Song, L. S., Nov 2009, In : Journal of Molecular and Cellular Cardiology. 47, 5, p. 706-715 10 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Sarcoplasmic Reticulum
Membrane Potentials
Genetic Models
Action Potentials
2008

Differential regulated interactions of calcium/calmodulin-dependent protein kinase II with isoforms of voltage-gated calcium channel β subunits

Grueter, C. E., Abiria, S. A., Wu, Y., Anderson, M. & Colbran, R. J., Feb 12 2008, In : Biochemistry®. 47, 6, p. 1760-1767 8 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Calcium-Calmodulin-Dependent Protein Kinases
Calcium Channels
Protein Isoforms
Electric potential

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

Le Scouarnec, S., Bhasin, N., Vieyres, C., Hund, T. J., Cunha, S. R., Koval, O., Marionneau, C., Chen, B., Wu, Y., Demolombe, S., Song, L. S., Le Marec, H., Probst, V., Schott, J. J., Anderson, M. & Mohler, P. J., Oct 7 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 40, p. 15617-15622 6 p.

Research output: Contribution to journalArticle

Ankyrins
Sick Sinus Syndrome
Ion Channels
Sinoatrial Node
Molecular Biology
2006

Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy

Khoo, M. S. C., Li, J., Singh, M. V., Yang, Y., Kannankeril, P., Wu, Y., Grueter, C. E., Guan, X., Oddis, C. V., Zhang, R., Mendes, L., Ni, G., Madu, E. C., Yang, J., Bass, M., Gomez, R. J., Wadzinski, B. E., Olson, E. N., Colbran, R. J. & Anderson, M., Sep 2006, In : Circulation. 114, 13, p. 1352-1359 8 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Calcineurin
Cardiomyopathies
Cardiac Arrhythmias
Transgenic Mice

L-Type Ca2+ Channel Facilitation Mediated by Phosphorylation of the β Subunit by CaMKII

Grueter, C. E., Abiria, S. A., Dzhura, I., Wu, Y., Ham, A. J. L., Mohler, P. J., Anderson, M. & Colbran, R. J., Sep 1 2006, In : Molecular Cell. 23, 5, p. 641-650 10 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Phosphorylation
Calcium Channels
Cardiac Myocytes
Mutation

Suppression of dynamic Ca2+ transient responses to pacing in ventricular myocytes from mice with genetic calmodulin kinase II inhibition

Wu, Y., Shintani, A., Grueter, C., Zhang, R., Hou, Y., Yang, J., Kranias, E. G., Colbran, R. J. & Anderson, M., Feb 2006, In : Journal of Molecular and Cellular Cardiology. 40, 2, p. 213-223 11 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Calcium-Calmodulin-Dependent Protein Kinases
Muscle Cells
Sarcoplasmic Reticulum
Genetic Models
2005

Atrial fibrillation in KCNE1-null mice

Temple, J., Frias, P., Rottman, J., Yang, T., Wu, Y., Verheijck, E. E., Zhang, W., Siprachanh, C., Kanki, H., Atkinson, J. B., King, P., Anderson, M., Kupershmidt, S. & Roden, D. M., Jul 8 2005, In : Circulation Research. 97, 1, p. 62-69 8 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Action Potentials
KCNQ1 Potassium Channel
Ventricular Function
CHO Cells

Calmodulin kinase II inhibition protects against structural heart disease

Zhang, R., Khoo, M. S. C., Wu, Y., Yang, Y., Grueter, C. E., Ni, G., Price, E. E., Thiel, W., Guatimosim, S., Song, L. S., Madu, E. C., Shah, A. N., Vishnivetskaya, T. A., Atkinson, J. B., Gurevich, V. V., Salama, G., Lederer, W. J., Colbran, R. J. & Anderson, M., Apr 2005, In : Nature Medicine. 11, 4, p. 409-417 9 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Adrenergic Receptors
Heart Diseases
Excitation Contraction Coupling
2004

Calmodulin kinase is functionally targeted to the action potential plateau for regulation of L-type Ca2+ current in rabbit cardiomyocytes

Wu, Y., Kimbrough, J. T., Colbran, R. J. & Anderson, M., Jan 1 2004, In : Journal of Physiology. 554, 1, p. 145-155 11 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Sarcoplasmic Reticulum
Cardiac Myocytes
Action Potentials
Rabbits
2003

C terminus L-type Ca2+ channel calmodulin-binding domains are 'auto-agonist' ligands in rabbit ventricular myocytes

Dzhura, I., Wu, Y., Zhang, R., Colbran, R. J., Hamilton, S. L. & Anderson, M., Aug 1 2003, In : Journal of Physiology. 550, 3, p. 731-738 8 p.

Research output: Contribution to journalArticle

Calmodulin
Muscle Cells
Rabbits
Ligands
Protein Kinases

Erratum: (The Journal of Physiology (2002) vol. 545 (399-406))

Dzhura, I., Wu, Y., Colbran, R. J., Corbin, J. D., Balser, J. R. & Anderson, M., Feb 1 2003, In : Journal of Physiology. 546, 3, p. 955 1 p.

Research output: Contribution to journalArticle

2002

Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy

Wu, Y., Temple, J., Zhang, R., Dzhura, I., Zhang, W., Trimble, R., Roden, D. M., Passier, R., Olson, E. N., Colbran, R. J. & Anderson, M., Sep 3 2002, In : Circulation. 106, 10, p. 1288-1293 6 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Cardiomegaly
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Cardiac Arrhythmias
Isoproterenol

Cytoskeletal disrupting agents prevent calmodulin kinase, IQ domain and voltage-dependent facilitation of L-type Ca2+ channels

Dzhura, I., Wu, Y., Colbran, R. J., Corbin, J. D., Balser, J. R. & Anderson, M., Dec 1 2002, In : Journal of Physiology. 545, 2, p. 399-406 8 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Nocodazole
Cytochalasin D
Calmodulin
Cell Membrane

Reduced repolarization reserve in ventricular myocytes from female mice

Wu, Y. & Anderson, M., Feb 15 2002, In : Cardiovascular Research. 53, 3, p. 763-769 7 p.

Research output: Contribution to journalArticle

pamidronate
Muscle Cells
Tacrolimus
Action Potentials
2001

Calmodulin kinase and a calmodulin-binding 'IQ' domain facilitate L-type Ca2+ current in rabbit ventricular myocytes by a common mechanism

Wu, Y., Dzhura, I., Colbran, R. J. & Anderson, M., Sep 15 2001, In : Journal of Physiology. 535, 3, p. 679-687 9 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Calmodulin
Muscle Cells
Rabbits
Peptides
Excitation Contraction Coupling
Calcium-Calmodulin-Dependent Protein Kinases
Sarcoplasmic Reticulum
Cardiac Myocytes
Ryanodine Receptor Calcium Release Channel
Calcium-Calmodulin-Dependent Protein Kinases
Phosphotransferases
Cardiac Arrhythmias
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Cardiac Glycosides
2000

Altered L-type Ca2+ channel currents in vascular smooth muscle cells from experimental diabetic rats

Wang, R., Wu, Y., Tang, G., Wu, L. & Hanna, S. T., Mar 2000, In : American Journal of Physiology - Heart and Circulatory Physiology. 278, 3 47-3

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Diabetes Complications
Nifedipine
Hyperglycemia

Ca2+-activated non-selective cation current in rabbit ventricular myocytes

Wu, Y. & Anderson, M., Jan 1 2000, In : Journal of Physiology. 522, 1, p. 51-57 7 p.

Research output: Contribution to journalArticle

Niflumic Acid
Monovalent Cations
Muscle Cells
Cations
Sarcoplasmic Reticulum

Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels

Dzhura, I., Wu, Y., Colbran, R. J., Balser, J. R. & Anderson, M., 2000, In : Nature Cell Biology. 2, 3, p. 173-177 5 p.

Research output: Contribution to journalArticle

Calmodulin-Binding Proteins
L-Type Calcium Channels
Calcium-Calmodulin-Dependent Protein Kinases
Protein Kinases
Phosphorylation

Determinants for calmodulin binding on voltage-dependent Ca2+ channels

Pate, P., Mochca-Morales, J., Wu, Y., Zhang, J. Z., Rodney, G. G., Serysheva, I. I., Williams, B. Y., Anderson, M. & Hamilton, S. L., Dec 15 2000, In : Journal of Biological Chemistry. 275, 50, p. 39786-39792 7 p.

Research output: Contribution to journalArticle

Calmodulin
Electric potential
Binding Sites
L-Type Calcium Channels
Peptides
1999

Calmodulin kinase inhibition prevents development of the arrhythmogenic transient inward current

Wu, Y., Roden, D. M. & Anderson, M., Apr 30 1999, In : Circulation Research. 84, 8, p. 906-912 7 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Action Potentials
Sarcoplasmic Reticulum
Peptides
Cardiac Arrhythmias

CaM kinase augments cardiac L-type Ca2+ current: A cellular mechanism for long Q-T arrhythmias

Wu, Y., MacMillan, L. B., McNeill, R. B., Colbran, R. J. & Anderson, M., 1999, In : American Journal of Physiology - Heart and Circulatory Physiology. 276, 6 45-6

Research output: Contribution to journalArticle

Cardiac Arrhythmias
Phosphotransferases
Calcium-Calmodulin-Dependent Protein Kinase Type 1
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Ryanodine

CaM kinase augments cardiac L-type Ca2+ current: A cellular mechanism for long Q-T arrhythmias

Wu, Y., Leigh, B., MacMillan, Blair McNeill, R., Colbran, R. J. & Anderson, M., 1999, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 276, 6 PART 2

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Cardiac Arrhythmias
Sarcoplasmic Reticulum
Action Potentials
Ryanodine
1997

Altered L-type Ca2+ channel currents in vascular smooth muscle cells from diabetic rats

Wang, R., Wu, Y. & Wu, L., 1997, In : FASEB Journal. 11, 3

Research output: Contribution to journalArticle

Vascular Smooth Muscle
blood vessels
smooth muscle
myocytes
Smooth Muscle Myocytes