Youngshim Choi

Research Associate

20082018
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2008 2018

2018
Liver
Adipose Tissue
Anti-Inflammatory Agents
Antioxidants
Alcohols
2017

Cytochrome P450-2E1 is involved in aging-related kidney damage in mice through increased nitroxidative stress

Abdelmegeed, M. A., Choi, Y., Ha, S. K. & Song, B. J., Nov 1 2017, In : Food and Chemical Toxicology. 109, p. 48-59 12 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2E1
cytochrome P-450
Aging of materials
kidneys
Kidney

Cytochrome P450-2E1 promotes fast food-mediated hepatic fibrosis

Abdelmegeed, M. A., Choi, Y., Godlewski, G., Ha, S. K., Banerjee, A., Jang, S. & Song, B. J., Jan 4 2017, In : Scientific Reports. 7, 39764.

Research output: Contribution to journalArticle

Fast Foods
Cytochrome P-450 CYP2E1
Fibrosis
Liver
Endoplasmic Reticulum Stress
Oxidative stress
fatty liver
Fatty Liver
Nutrition
Fructose

Role of CYP2E1 in mitochondrial dysfunction and hepatic injury by alcohol and non-alcoholic substances

Abdelmegeed, M. A., Ha, S. K., Choi, Y., Akbar, M. & Song, B. J., Aug 1 2017, In : Current Molecular Pharmacology. 10, 3, p. 207-225 19 p.

Research output: Contribution to journalReview article

Cytochrome P-450 CYP2E1
Alcoholic Fatty Liver
Alcoholic Liver Diseases
Alcohols
Liver
2016

Cytochrome P450-2E1 promotes aging-related hepatic steatosis, apoptosis and fibrosis through increased nitroxidative stress

Abdelmegeed, M. A., Choi, Y., Ha, S. K. & Song, B. J., Feb 1 2016, In : Free Radical Biology and Medicine. 91, p. 188-202 15 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2E1
Fibrosis
Aging of materials
Liver
Apoptosis

Dietary walnut reduces hepatic triglyceride content in high-fat-fed mice via modulation of hepatic fatty acid metabolism and adipose tissue inflammation

Choi, Y., Abdelmegeed, M. A., Akbar, M. & Song, B. J., Apr 1 2016, In : Journal of Nutritional Biochemistry. 30, p. 116-125 10 p.

Research output: Contribution to journalArticle

Juglans
Metabolism
High Fat Diet
Nutrition
Adipose Tissue

Increased expression of FGF1-mediated signaling molecules in adipose tissue of obese mice

Choi, Y., Jang, S., Choi, M. S., Ryoo, Z. Y. & Park, T., Jun 1 2016, In : Journal of Physiology and Biochemistry. 72, 2, p. 157-167 11 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Obese Mice
Nutrition
Adipose Tissue
Receptor, Fibroblast Growth Factor, Type 1

Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stress

Akbar, M., Essa, M. M., Daradkeh, G., Abdelmegeed, M. A., Choi, Y., Mahmood, L. & Song, B. J., Apr 15 2016, In : Brain Research. 1637, p. 34-55 22 p.

Research output: Contribution to journalArticle

Post Translational Protein Processing
Neurodegenerative Diseases
Reactive Oxygen Species
Mitochondria
Cell Death

Preventive effects of dietary walnuts on high-fat-induced hepatic fat accumulation, oxidative stress and apoptosis in mice

Choi, Y., Abdelmegeed, M. A. & Song, B. J., Dec 1 2016, In : Journal of Nutritional Biochemistry. 38, p. 70-80 11 p.

Research output: Contribution to journalArticle

Juglans
Oxidative stress
High Fat Diet
Nutrition
Oxidative Stress
2014

Dietary camphene attenuates hepatic steatosis and insulin resistance in mice

Kim, S., Choi, Y., Choi, S., Choi, Y. & Park, T., Feb 1 2014, In : Obesity. 22, 2, p. 408-417 10 p.

Research output: Contribution to journalArticle

Insulin Resistance
High Fat Diet
Liver
Adiponectin
AMP-Activated Protein Kinases

Piperonal prevents high-fat diet-induced hepatic steatosis and insulin resistance in mice via activation of adiponectin/AMPK pathway

Li, X., Choi, Y., Yanakawa, Y. & Park, T., Jan 1 2014, In : International Journal of Obesity. 38, 1, p. 140-147 8 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Adiponectin
High Fat Diet
Insulin Resistance
Liver
2013

Carvacrol protects against hepatic steatosis in mice fed a high-fat diet by enhancing SIRT1-AMPK signaling

Kim, E., Choi, Y., Jang, J. & Park, T., Mar 15 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 290104.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
High Fat Diet
Liver
Phosphorylation
Ribosomal Protein S6 Kinases

Indole-3-carbinol directly targets SIRT1 to inhibit adipocyte differentiation

Choi, Y., Um, S. J. & Park, T., Jun 1 2013, In : International Journal of Obesity. 37, 6, p. 881-884 4 p.

Research output: Contribution to journalArticle

Adipocytes
3T3-L1 Cells
Brassica
Sirtuin 1
indole-3-carbinol
Smell
Neoplasm Genes
High Fat Diet
high fat diet
Nutrition

Involvement of SIRT1-AMPK signaling in the protective action of indole-3-carbinol against hepatic steatosis in mice fed a high-fat diet

Choi, Y., Yanagawa, Y., Kim, S. & Park, T., Jul 1 2013, In : Journal of Nutritional Biochemistry. 24, 7, p. 1393-1400 8 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
High Fat Diet
Nutrition
Fats
Liver

Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice

Choi, S., Choi, Y., Choi, Y., Kim, S., Jang, J. & Park, T., Jan 1 2013, In : Food Chemistry. 141, 4, p. 3627-3635 9 p.

Research output: Contribution to journalArticle

piperine
fatty liver
High Fat Diet
high fat diet
Nutrition
2012

Antilipogenic and anti-inflammatory activities of Codonopsis lanceolata in mice hepatic tissues after chronic ethanol feeding

Cha, A., Choi, Y., Jin, Y., Sung, M. K., Koo, Y. C., Lee, K. W. & Park, T., Jan 3 2012, In : Journal of Biomedicine and Biotechnology. 2012, 141395.

Research output: Contribution to journalArticle

Codonopsis
Methanol
Anti-Inflammatory Agents
Ethanol
Liver

Carvacrol prevents diet-induced obesity by modulating gene expressions involved in adipogenesis and inflammation in mice fed with high-fat diet

Cho, S., Choi, Y., Park, S. & Park, T., Feb 1 2012, In : Journal of Nutritional Biochemistry. 23, 2, p. 192-201 10 p.

Research output: Contribution to journalArticle

Adipogenesis
High Fat Diet
Nutrition
Gene expression
Obesity
Adipogenesis
Intra-Abdominal Fat
Thermogenesis
Nutrition
Obesity

Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice

Kim, S. J., Choi, Y., Choi, Y. H. & Park, T., Feb 1 2012, In : Journal of Nutritional Biochemistry. 23, 2, p. 113-122 10 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Adipose Tissue
Obesity
Tissue
Nutrition

Piperine, an LXRα antagonist, protects against hepatic steatosis and improves insulin signaling in mice fed a high-fat diet

Jwa, H., Choi, Y., Park, U. H., Um, S. J., Yoon, S. K. & Park, T., Dec 1 2012, In : Biochemical Pharmacology. 84, 11, p. 1501-1510 10 p.

Research output: Contribution to journalArticle

piperine
High Fat Diet
Nutrition
Liver
Fats
2011

Oleuropein attenuates hepatic steatosis induced by high-fat diet in mice

Park, S., Choi, Y., Um, S. J., Yoon, S. K. & Park, T., May 1 2011, In : Journal of Hepatology. 54, 5, p. 984-993 10 p.

Research output: Contribution to journalArticle

High Fat Diet
Liver
Receptor, Fibroblast Growth Factor, Type 1
Diet
Down-Regulation

Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice

Kim, S., Jin, Y., Choi, Y. & Park, T., Jun 1 2011, In : Biochemical Pharmacology. 81, 11, p. 1343-1351 9 p.

Research output: Contribution to journalArticle

Down-Regulation
Nutrition
Obesity
High Fat Diet
Fats
2010

Hepatoprotective effect of oleuropein in mice: Mechanisms uncovered by gene expression profiling

Kim, Y., Choi, Y. & Park, T., Sep 1 2010, In : Biotechnology Journal. 5, 9, p. 950-960 11 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
High Fat Diet
Liver
Genes
Transcription Factors

High-fat diet stimulates IL-1 type I receptor-mediated inflammatory signaling in the skeletal muscle of mice

Kim, S. J., Choi, Y., Jun, H. S., Kim, B. M., Na, H. K., Surh, Y. J. & Park, T., Jul 1 2010, In : Molecular Nutrition and Food Research. 54, 7, p. 1014-1020 7 p.

Research output: Contribution to journalArticle

Interleukin-1 Receptors
interleukin-1
High Fat Diet
high fat diet
skeletal muscle
2008

Ilex paraguariensis extract ameliorates obesity induced by high-fat diet: Potential role of AMPK in the visceral adipose tissue

Pang, J., Choi, Y. & Park, T., Aug 15 2008, In : Archives of Biochemistry and Biophysics. 476, 2, p. 178-185 8 p.

Research output: Contribution to journalArticle

Ilex paraguariensis
AMP-Activated Protein Kinases
Intra-Abdominal Fat
High Fat Diet
Nutrition