Young Choi

Assistant Professor

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  • 4 Similar Profiles
Human Herpesvirus 8 Medicine & Life Sciences
Human herpesvirus 8 Agriculture & Biology
src Homology Domains Medicine & Life Sciences
Lymphocyte Specific Protein Tyrosine Kinase p56(lck) Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Viral Proteins Medicine & Life Sciences
T-cells Chemical Compounds
Mitochondrial Degradation Medicine & Life Sciences

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Research Output 1998 2019

Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirus

Vo, M. T., Smith, B. J., Nicholas, J. & Choi, Y., Dec 1 2019, In : Nature communications. 10, 1, 3203.

Research output: Contribution to journalArticle

Open Access
Mitochondrial Degradation
Interferon Regulatory Factors
Human Herpesvirus 8

Human herpesvirus 8 interferon regulatory factors 1 and 3 mediate replication and latency activities via interactions with USP7 deubiquitinase

Xiang, Q., Ju, H., Li, Q., Mei, S. C., Chen, D., Choi, Y. & Nicholas, J., Apr 1 2018, In : Journal of Virology. 92, 7, e02003-17.

Research output: Contribution to journalArticle

Human herpesvirus 8
Ubiquitin-Specific Proteases

Peroxisomes support human herpesvirus 8 latency by stabilizing the viral oncogenic protein vFLIP via the MAVS-TRAF complex

Choi, Y., Choi, Y. & Harhaj, E. W., May 1 2018, In : PLoS Pathogens. 14, 5, e1007058.

Research output: Contribution to journalArticle

CASP8 and FADD-Like Apoptosis Regulating Protein
Human Herpesvirus 8
Viral Proteins
Antiviral Agents

TAX1BP1 restrains virus-induced apoptosis by facilitating itch-mediated degradation of the mitochondrial adaptor MAVS

Choi, Y., Shembade, N., Parvatiyar, K., Balachandran, S. & Harhaj, E. W., 2017, In : Molecular and Cellular Biology. 37, 1, e00422-16.

Research output: Contribution to journalArticle

RNA Virus Infections
Sendai virus
Virus Activation

The Itch ubiquitin ligase is required for KSHV RTA induced vFLIP degradation

Chmura, J. C., Herold, K., Ruffin, A., Atuobi, T., Fabiyi, Y., Mitchell, A. E., Choi, Y. & Ehrlich, E. S., Jan 15 2017, In : Virology. 501, p. 119-126 8 p.

Research output: Contribution to journalArticle

Human Herpesvirus 8
Kaposi's Sarcoma