Yoichi Araki

Research Associate

20032018
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Metabolism Chemical Compounds
AMPA Receptors Medicine & Life Sciences
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Research Output 2003 2018

Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease

Yamada, T., Murata, D., Adachi, Y., Itoh, K., Kameoka, S., Igarashi, A., Kato, T., Araki, Y., Huganir, R. L., Dawson, T. M., Yanagawa, T., Okamoto, K., Iijima, M. & Sesaki, H., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Ubiquitination
Liver
Mitochondria
Cullin Proteins

BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method

Lim, C. S., Kang, X., Mirabella, V., Zhang, H., Bu, Q., Araki, Y., Hoang, E. T., Wang, S., Shen, Y., Choi, S., Kaang, B. K., Chang, Q., Pang, Z. P., Huganir, R. L. & Zhu, J. J., Mar 15 2017, In : Genes & development. 31, 6, p. 537-552 16 p.

Research output: Contribution to journalArticle

Lentivirus
Mutation
Precision Medicine
Genes
Neurons

Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity

Zeng, M., Shang, Y., Araki, Y., Guo, T., Huganir, R. L. & Zhang, M., Aug 25 2016, In : Cell. 166, 5, p. 1163-1175.e12

Research output: Contribution to journalArticle

Post-Synaptic Density
Neuronal Plasticity
Phase Transition
Phase separation
GTP Phosphohydrolase Activators

Cytoplasmic fragment of Alcadein α generated by regulated intramembrane proteolysis enhances amyloid β-protein precursor (APP) transport into the late secretory pathway and facilitates APP cleavage

Takei, N., Sobu, Y., Kimura, A., Urano, S., Piao, Y., Araki, Y., Taru, H., Yamamoto, T., Hata, S., Nakaya, T. & Suzuki, T., Jan 9 2015, In : Journal of Biological Chemistry. 290, 2, p. 987-995 9 p.

Research output: Contribution to journalArticle

Proteolysis
Amyloid beta-Protein Precursor
Secretory Pathway
Protein Transport
Amyloid Precursor Protein Secretases

Rapid Dispersion of SynGAP from Synaptic Spines Triggers AMPA Receptor Insertion and Spine Enlargement during LTP

Araki, Y., Zeng, M., Zhang, M. & Huganir, R. L., Jan 7 2015, In : Neuron. 85, 1, p. 173-190 18 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
AMPA Receptors
Spine
MAP Kinase Signaling System
ras GTPase-Activating Proteins