Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Glioma Medicine & Life Sciences
Glycosylphosphatidylinositols Medicine & Life Sciences
Idoxuridine Medicine & Life Sciences
Paroxysmal Hemoglobinuria Medicine & Life Sciences
tirapazamine Medicine & Life Sciences
Polymers Medicine & Life Sciences
Induced Pluripotent Stem Cells Medicine & Life Sciences
Hemangioblasts Medicine & Life Sciences

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Research Output 1998 2017

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model

Yuan, X., Li, Z., Baines, A. C., Gavriilaki, E., Ye, Z., Wen, Z., Braunstein, E. M., Biesecker, L. G., Cheng, L., Dong, X. & Brodsky, R. A. Apr 1 2017 In : PLoS ONE. 12, 4, e0174074

Research output: Contribution to journalArticle

Glycosylphosphatidylinositols
Neurons
Toxicity
complement
neurodevelopment

Eculizumab cessation in atypical hemolytic uremic syndrome

Merrill, S. A., Brittingham, Z. D., Yuan, X., Moliterno, A. R., Sperati, C. J. & Brodsky, R. A. Jul 20 2017 In : Blood. 130, 3, p. 368-372 5 p.

Research output: Contribution to journalLetter

eculizumab
Atypical Hemolytic Uremic Syndrome

Hypotonia and intellectual disability without dysmorphic features in a patient with PIGN-related disease

Thiffault, I., Zuccarelli, B., Welsh, H., Yuan, X., Farrow, E., Zellmer, L., Miller, N., Soden, S., Abdelmoity, A., Brodsky, R. A. & Saunders, C. Nov 2 2017 In : BMC Medical Genetics. 18, 1, 124

Research output: Contribution to journalArticle

Muscle Hypotonia
Intellectual Disability
Glycosylphosphatidylinositols
Exome
Phenotype

Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome

Yuan, X., Gavriilaki, E., Thanassi, J. A., Yang, G., Baines, A. C., Podos, S. D., Huang, Y., Huang, M. & Brodsky, R. A. Feb 28 2017 In : Haematologica. 102, 3, p. 466-475 10 p.

Research output: Contribution to journalArticle

Complement Factor D
Alternative Complement Pathway
Paroxysmal Hemoglobinuria
Hemolysis
Complement C5

Direct evidence of complement activation in HELLP syndrome: A link to atypical hemolytic uremic syndrome

Vaught, A. J., Gavriilaki, E., Hueppchen, N., Blakemore, K., Yuan, X., Seifert, S. M., York, S. & Brodsky, R. A. May 1 2016 In : Experimental Hematology. 44, 5, p. 390-398 9 p.

Research output: Contribution to journalArticle

HELLP Syndrome
Complement Activation
Serum
Complement Inactivating Agents
Pre-Eclampsia