Xiaolei Zhu

Instructor

20152019
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Research Output 2015 2019

  • 8 Article
  • 1 Comment/debate
  • 1 Review article
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Article
2019

Altered brain function in drug-naïve major depressive disorder patients with early-life maltreatment: A resting-state fMRI study

Xu, Z., Zhang, J., Wang, D., Wang, T., Zhang, S., Ren, X., Zhu, X., Kamiya, A., Fang, J. & Qu, M., Jan 1 2019, In : Frontiers in Psychiatry. 10, APR, 255.

Research output: Contribution to journalArticle

Open Access
Major Depressive Disorder
Magnetic Resonance Imaging
Brain
Pharmaceutical Preparations
Prefrontal Cortex

Glutamine Antagonist JHU083 Normalizes Aberrant Glutamate Production and Cognitive Deficits in the EcoHIV Murine Model of HIV-Associated Neurocognitive Disorders

Nedelcovych, M. T., Kim, B. H., Zhu, X., Lovell, L. E., Manning, A. A., Kelschenbach, J., Hadas, E., Chao, W., Prchalová, E., Dash, R. P., Wu, Y., Alt, J., Thomas, A. G., Rais, R., Kamiya, A., Volsky, D. J. & Slusher, B., Jan 1 2019, In : Journal of Neuroimmune Pharmacology.

Research output: Contribution to journalArticle

Glutaminase
Glutamine
Norleucine
Glutamic Acid
HIV
2018
Dronabinol
Astrocytes
Cannabis
Schizophrenia
Parvalbumins

Altered resting-state brain activities in drug-naïve major depressive disorder assessed by fMRI: Associations with somatic symptoms defined by Yin-Yang theory of the traditional Chinese Medicine

Xu, Z., Zhang, S., Huang, L., Zhu, X., Zhao, Q., Zeng, Y., Zhou, D., Wang, D., Kuga, H., Kamiya, A. & Qu, M., May 15 2018, In : Frontiers in Psychiatry. 9, MAY, 195.

Research output: Contribution to journalArticle

Yin-Yang
Chinese Traditional Medicine
Major Depressive Disorder
Magnetic Resonance Imaging
Brain

JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress

Zhu, X., Nedelcovych, M. T., Thomas, A. G., Hasegawa, Y., Moreno-Megui, A., Coomer, W., Vohra, V., Saito, A., Perez, G., Wu, Y., Alt, J., Prchalova, E., Tenora, L., Majer, P., Rais, R., Rojas, C., Slusher, B. & Kamiya, A., Jan 1 2018, (Accepted/In press) In : Neuropsychopharmacology.

Research output: Contribution to journalArticle

Glutaminase
Major Depressive Disorder
Glutamic Acid
Microglia
Depression
2017

De novo non-synonymous TBL1XR1 mutation alters Wnt signaling activity

Nishi, A., Numata, S., Tajima, A., Zhu, X., Ito, K., Saito, A., Kato, Y., Kinoshita, M., Shimodera, S., Ono, S., Ochi, S., Imamura, A., Kurotaki, N., Ueno, S. I., Iwata, N., Fukui, K., Imoto, I., Kamiya, A. & Ohmori, T., Dec 1 2017, In : Scientific Reports. 7, 1, 2887.

Research output: Contribution to journalArticle

Mutation
Catenins
Nucleotides
Exome
Protein Stability

Developmental alcohol exposure impairs activity-dependent S-nitrosylation of NDEL1 for neuronal maturation

Saito, A., Taniguchi, Y., Kim, S-H., Selvakumar, B., Perez, G., Ballinger, M. D., Zhu, X., Sabra, J., Jallow, M., Yan, P., Ito, K., Rajendran, S., Hirotsune, S., Wynshaw-Boris, A., Snyder, S. H., Sawa, A. & Kamiya, A., Aug 1 2017, In : Cerebral Cortex. 27, 8, p. 3918-3929 12 p.

Research output: Contribution to journalArticle

Cyclic GMP
Alcohols
Brain
Maternal Exposure
Nitric Oxide Synthase Type I
2015

Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory

Ballinger, M. D., Saito, A., Abazyan, B., Taniguchi, Y., Huang, C. H., Ito, K., Zhu, X., Segal, H., Jaaro-Peled, H., Sawa, A., Mackie, K., Pletnikov, M. & Kamiya, A., Oct 1 2015, In : Neurobiology of Disease. 82, p. 176-184 9 p.

Research output: Contribution to journalArticle

Cannabis
Schizophrenia
Dronabinol
Fear
Brain