William Sharfman

Associate Professor

1990 …2019
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  • 3 Similar Profiles
Melanoma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Renal Cell Carcinoma Medicine & Life Sciences
Interleukin-2 Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Interferons Medicine & Life Sciences
Merkel Cell Carcinoma Medicine & Life Sciences

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Research Output 1990 2019

Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1 (Journal for Immuno Therapy of Cancer (2019) 7 (40) DOI: 10.1186/s40425-018-0492-x)

Smith, K., Llosa, N., Cottrell, T. R., Siegel, N., Fan, H., Suri, P., Chan, H. Y., Guo, H., Oke, T., Awan, A. H., Verde, F., Danilova, L. V., Anagnostou, V., Tam, A. J., Luber, B. S., Bartlett, B. R., Aulakh, L. K., Sidhom, J. W., Zhu, Q., Sears, C. L. & 21 others, Cope, L., Sharfman, W., Thompson, E., Riemer, J., Marrone, K., Naidoo, J., Velculescu, V. E., Forde, P., Vogelstein, B., Kinzler, K. W., Papadopoulos, N., Durham, J. N., Wang, H., Le, D., Justesen, S., Taube, J. M., Diaz, L. A., Brahmer, J., Pardoll, A. M., Anders, R. A. & Housseau, F., Mar 6 2019, In : Journal for immunotherapy of cancer. 7, 1, 7.

Research output: Contribution to journalComment/debate

Consultants
Oncogenes
T-Lymphocytes
Conflict of Interest
Organized Financing

Durable tumor regression and overall survival in patients with advanced Merkel cell carcinoma receiving pembrolizumab as first-line therapy

Nghiem, P., Bhatia, S., Lipson, E., Sharfman, W., Kudchadkar, R. R., Brohl, A. S., Friedlander, P. A., Daud, A., Kluger, H. M., Reddy, S. A., Boulmay, B. C., Riker, A. I., Burgess, M. A., Hanks, B. A., Olencki, T., Margolin, K., Lundgren, L. M., Soni, A., Ramchurren, N., Church, C. & 11 others, Park, S. Y., Shinohara, M. M., Salim, B., Taube, J. M., Bird, S. R., Ibrahim, N., Fling, S. P., Moreno, B. H., Sharon, E., Cheever, M. A. & Topalian, S., Mar 20 2019, In : Journal of Clinical Oncology. 37, 9, p. 693-702 10 p.

Research output: Contribution to journalArticle

Merkel Cell Carcinoma
Disease-Free Survival
Survival
Neoplasms
Merkel cell polyomavirus

Major pathologic response on biopsy (MPRbx) in patients with advanced melanoma treated with anti-PD-1: evidence for an early, on-therapy biomarker of response

Stein, J. E., Soni, A., Danilova, L. V., Cottrell, T. R., Gajewski, T. F., Hodi, F. S., Bhatia, S., Urba, W. J., Sharfman, W., Wind-Rotolo, M., Edwards, R., Lipson, E. & Taube, J. M., Apr 1 2019, In : Annals of oncology : official journal of the European Society for Medical Oncology. 30, 4, p. 589-596 8 p.

Research output: Contribution to journalArticle

Open Access
Secondary Prevention
Melanoma
Biomarkers
Biopsy
Therapeutics

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

Smith, K., Llosa, N., Cottrell, T. R., Siegel, N., Fan, H., Suri, P., Chan, H. Y., Guo, H., Oke, T., Awan, A. H., Verde, F., Danilova, L. V., Anagnostou, V., Tam, A. J., Luber, B. S., Bartlett, B. R., Aulakh, L. K., Sidhom, J. W., Zhu, Q., Sears, C. L. & 21 others, Cope, L., Sharfman, W., Thompson, E., Riemer, J., Marrone, K., Naidoo, J., Velculescu, V. E., Forde, P., Vogelstein, B., Kinzler, K. W., Papadopoulos, N., Durham, J. N., Wang, H., Le, D., Justesen, S., Taube, J. M., Diaz, L. A., Brahmer, J., Pardoll, A. M., Anders, R. A. & Housseau, F., Feb 11 2019, In : Journal for immunotherapy of cancer. 7, 1, 40.

Research output: Contribution to journalArticle

Open Access
Oncogenes
T-Lymphocytes
Biomarkers
DNA Mismatch Repair
Neoplasms

Rescue therapy for patients with anti-PD-1-refractory Merkel cell carcinoma: A multicenter, retrospective case series

Lopiccolo, J., Schollenberger, M. D., Dakhil, S., Rosner, S., Ali, O., Sharfman, W., Silk, A. W., Bhatia, S. & Lipson, E., Jul 8 2019, In : Journal for immunotherapy of cancer. 7, 1, 170.

Research output: Contribution to journalArticle

Open Access
Merkel Cell Carcinoma
Therapeutics
Neoplasms
Blocking Antibodies
Multicenter Studies