William Ramses Bishai

Professor

1979 …2018
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Research Output 1979 2018

Diverse Cavity Types and Evidence that Mechanical Action on the Necrotic Granuloma Drives Tuberculous Cavitation

Ihms, E. A., Urbanowski, M. E. & Bishai, W. R., Jul 1 2018, In : American Journal of Pathology. 188, 7, p. 1666-1675 10 p.

Research output: Contribution to journalArticle

Mechanical Stress
Granuloma
Lipid Pneumonia
Lung
Aerosols

Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis

Zhang, W., Lun, S., Wang, S. H., Jiang, X. W., Yang, F., Tang, J., Manson, A. L., Earl, A. M., Gunosewoyo, H., Bishai, W. R. & Yu, L. F., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 791-803 13 p.

Research output: Contribution to journalArticle

Mycolic Acids
Antitubercular Agents
Polyketide Synthases
Mycobacterium tuberculosis
Benzofurans

Lysosomal cathepsin release is required for NLRP3-inflammasome activation by Mycobacterium tuberculosis in infected macrophages

Amaral, E. P., Riteau, N., Moayeri, M., Maier, N., Mayer-Barber, K. D., Pereira, R. M., Lage, S. L., Kubler, A., Bishai, W. R., D'Império-Lima, M. R., Sher, A. & Andrade, B. B., Jun 21 2018, In : Frontiers in Immunology. 9, JUN, 1427

Research output: Contribution to journalArticle

Inflammasomes
Cathepsins
Cathepsin B
Mycobacterium tuberculosis
Macrophages

Organoid culture of bladder cancer cells

Yoshida, T., Singh, A. K., Bishai, W. R., McConkey, D. J. & Bivalacqua, T. J., May 1 2018, In : Investigative and Clinical Urology. 59, 3, p. 149-151 3 p.

Research output: Contribution to journalEditorial

Organoids
Urinary Bladder Neoplasms

Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data

Rifat, D., Prideaux, B., Savic, R. M., Urbanowski, M. E., Parsons, T. L., Luna, B., Marzinke, M. A., Ordonez, A. A., DeMarco, V. P., Jain, S. K., Dartois, V., Bishai, W. R. & Dooley, K. E., Apr 4 2018, In : Science Translational Medicine. 10, 435, eaai7786

Research output: Contribution to journalArticle

rifapentine
Rifampin
Tuberculosis
Pharmacokinetics
Clinical Trials