William Osburn

Assistant Professor

20062018
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Hepacivirus Medicine & Life Sciences
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Vaccines Medicine & Life Sciences
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Research Output 2006 2018

Complex patterns of Hepatitis-C virus longitudinal clustering in a high-risk population

Rose, R., Lamers, S. L., Massaccesi, G., Osburn, W., Ray, S. C., Thomas, D. L., Cox, A. L. & Laeyendecker, O., Mar 1 2018, In : Infection, Genetics and Evolution. 58, p. 77-82 6 p.

Research output: Contribution to journalArticle

hepatitis
Hepatitis C virus
Hepacivirus
Cluster Analysis
virus

Rapid and sensitive detection of viral nucleic acids using silicon microchips

Powell, L., Wiederkehr, R. S., Damascus, P., Fauvart, M., Buja, F., Stakenborg, T., Ray, S. C., Fiorini, P. & Osburn, W. O., Jun 7 2018, In : Analyst. 143, 11, p. 2596-2603 8 p.

Research output: Contribution to journalArticle

Nucleic acids
nucleic acid
Silicon
Nucleic Acids
silicon

Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1

El-Diwany, R., Cohen, V. J., Mankowski, M. C., Wasilewski, L. N., Brady, J. K., Snider, A. E., Osburn, W. O., Murrell, B., Ray, S. C. & Bailey, J. R., Feb 1 2017, In : PLoS Pathogens. 13, 2, e1006235

Research output: Contribution to journalArticle

Scavenger Receptors
Neutralizing Antibodies
Hepacivirus
Epitopes
Monoclonal Antibodies

Limited naturally occurring escape in broadly neutralizing antibody epitopes in hepatitis C glycoprotein E2 and constrained sequence usage in acute infection

Rodrigo, C. , Walker, M. R. , Leung, P. , Eltahla, A. A. , Grebely, J. , Dore, G. J. , Applegate, T. , Page, K. , Dwivedi, S. , Bruneau, J. , Morris, M. D. , Cox, A. L. , Osburn, W. , Kim, A. Y. , Schinkel, J. , Shoukry, N. H. , Lauer, G. M. , Maher, L. , Hellard, M. , Prins, M. & 3 others Luciani, F., Lloyd, A. R. & Bull, R. A., Apr 1 2017, In : Infection, Genetics and Evolution. 49, p. 88-96 9 p.

Research output: Contribution to journalArticle

hepatitis C
hepatitis
Hepatitis C
Neutralizing Antibodies
neutralizing antibodies

New therapies for treating hepatitis C virus: Impact on laboratory testing recommendations and clinical management

Tolan, N. V., Horowitz, G. L., Graham, C. S., Hillyard, D., Osburn, W. & Ray, S., Dec 1 2017, In : Clinical Chemistry. 63, 12, p. 1799-1805 7 p.

Research output: Contribution to journalComment/debate

Hepacivirus
Therapeutics