William Dalton

Assistant Professor

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Centrosome Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Mutation Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Mitosis Medicine & Life Sciences
Chromosomal Instability Medicine & Life Sciences
M Phase Cell Cycle Checkpoints Medicine & Life Sciences
Antimitotic Agents Medicine & Life Sciences

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Research Output 2003 2019

Acute Promyelocytic Leukemia

Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation

Brian Dalton, W., Helmenstine, E., Walsh, N., Gondek, L. P., Kelkar, D. S., Read, A., Natrajan, R., Christenson, E. S., Roman, B., Das, S., Zhao, L., Leone, R. D., Shinn, D., Groginski, T., Madugundu, A. K., Patil, A., Zabransky, D. J., Medford, A., Lee, J., Cole, A. J. & 12 others, Rosen, M., Thakar, M., Ambinder, A., Donaldson, J., DeZern, A. E., Cravero, K., Chu, D., Madero-Marroquin, R., Pandey, A., Hurley, P. J., Lauring, J. & Park, B. H., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4708-4723 16 p.

Research output: Contribution to journalArticle

Mitochondrial Genes

The estrogen receptor-alpha S118P variant does not affect breast cancer incidence or response to endocrine therapies

Button, B., Croessmann, S., Chu, D., Rosen, D. M., Zabransky, D. J., Dalton, W., Cravero, K., Kyker-Snowman, K., Waters, I., Karthikeyan, S., Christenson, E. S., Donaldson, J., Hunter, T., Dennison, L., Ramin, C., May, B., Roden, R. S., Petry, D., Armstrong, D. K., Visvanathan, K. & 1 others, Park, B. H., Jan 1 2018, (Accepted/In press) In : Breast Cancer Research and Treatment.

Research output: Contribution to journalArticle

Estrogen Receptor alpha
Breast Neoplasms
Mediator Complex

PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity

Croessmann, S., Wong, H. Y., Zabransky, D. J., Chu, D., Rosen, D. M., Cidado, J., Cochran, R. L., Dalton, W., Erlanger, B., Cravero, K., Button, B., Kyker-Snowman, K., Hurley, P., Lauring, J. & Park, B. H., Feb 11 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-14 14 p.

Research output: Contribution to journalArticle

Cell Line

Single-nucleotide polymorphism leading to false allelic fraction by droplet digital PCR

Christenson, E. S., Dalton, W., Chu, D., Waters, I., Cravero, K., Zabransky, D. J., Dezern, A. & Park, B. H., Aug 1 2017, In : Clinical Chemistry. 63, 8, p. 1370-1376 7 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism