Bill Clarke

Research output

Research output per year 1998 2010 2013 2014 2015 2016 2017 2018 2020 2021 2022 2023 2024

• 134 Article
• 14 Chapter
• 13 Review article
• 9 Letter
• 9 More
  • 3 Comment/debate
  • 2 Book
  • 2 Editorial
  • 1 Foreword/postscript
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2024

  Letter to the editor: Poor sensitivity of anti-nucleocapsid antibody in detecting prior COVID-19 in vaccinated solid organ transplant recipients

  Alejo, J. L., Chang, T. P. Y., Frey, S., Nair, G. A., Abedon, A. T., Nauroz, Z., Karaba, A., Avery, R., Tobian, A. A. R., Clarke, B., Garonzik, J., Segev, D., Massie, A. B. & Werbel, W. A., Jan 2024, In: Clinical Transplantation. 38, 1, e15233.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Toward point-of-care diagnostics: Running enzymatic assays on a photonic waveguide-based sensor chip with a portable, benchtop measurement system

  Neutens, P., Zinoviev, K., Jimenez Valencia, A. M., Woronoff, G., Jansen, R., Hosseini, N., Uribe, A. J., Goheen, J., Kryszak, L. A., Stakenborg, T., Clarke, W. A. & Van Roy, W., Jan 2024, In: Journal of biophotonics. 17, 1, e202300279.

  Research output: Contribution to journal › Article › peer-review

  • Optics and Photonics 100%
  • creatinine 89%
  • Creatinine 77%
  • Assays 75%
  • Enzyme Assays 73%
• 2023

  A Saliva-Based Serological and Behavioral Analysis of SARS-CoV-2 Antibody Prevalence in Howard County, Maryland

  Brown, A. C., Koshute, P. T., Cowley, H. P., Robinette, M. S., Gravelyn, S. R., Patel, S. V., Ju, E. Y., Frommer, C. T., Zambidis, A. E., Schneider, E. J., Zhao, M. Y., Mugo, B. K., Clarke, W., Kruczynski, K., Pisanic, N., Heaney, C. D. & Colella, T. A., Aug 2023, In: Microbiology Spectrum. 11, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe acute respiratory syndrome coronavirus 100%
  • severe acute respiratory syndrome 88%
  • saliva 74%
  • Severe Acute Respiratory Syndrome 74%
  • Coronavirus 72%

• Comprehensive profiling of pre-infection antibodies identifies HIV targets associated with viremic control and viral load

  Grant-McAuley, W., Morgenlander, W., Hudelson, S. E., Thakar, M., Piwowar-Manning, E., Clarke, W., Breaud, A., Blankson, J., Wilson, E., Ayles, H., Bock, P., Moore, A., Kosloff, B., Shanaube, K., Meehan, S. A., van Deventer, A., Fidler, S., Hayes, R., Ruczinski, I., Kammers, K., & 3 othersLaeyendecker, O. B., Larman, H. B. & Eshleman, S. H., 2023, In: Frontiers in immunology. 14, 1178520.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • HIV Antibodies 100%
  • Viral Load 75%
  • HIV 53%
  • Infections 37%
  • Epitopes 22%

• Factors Associated With Discordant A1C-Estimated and Measured Average Glucose Among Hospitalized Patients With Diabetes

  Wallam, S., Abusamaan, M. S., Clarke, W. & Mathioudakis, N., Mar 2023, In: Clinical Diabetes. 41, 2, p. 208-219 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glucose 100%
  • Inpatients 47%
  • Hypoglycemic Agents 37%
  • Glucocorticoids 36%
  • Secretagogues 24%

• Letter to the editor: “hook” (prozone) effect in sars-cov-2 anti-spike binding antibody levels following vaccination, infection, or monoclonal antibody in solid organ transplant recipients

  Abedon, A. T., Chiang, T. P. Y., Karaba, A. H., Alejo, J. L., Chahoud, M., Hussey, C., Lopes, J. F., Hussain, S., Larsen, C. P., Durand, C. M., Heeger, P. S., Segev, D. L., Clarke, W. A. & Werbel, W. A., Aug 2023, In: Clinical Transplantation. 37, 8, e15044.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Methodological approaches to optimize multiplex oral fluid SARS-CoV-2 IgG assay performance and correlation with serologic and neutralizing antibody responses

  Pisanic, N., Antar, A. A. R., Kruczynski, K. L., Gregory Rivera, M., Dhakal, S., Spicer, K., Randad, P. R., Pekosz, A., Klein, S. L., Betenbaugh, M. J., Detrick, B., Clarke, W., Thomas, D. L., Manabe, Y. C. & Heaney, C. D., Mar 2023, In: Journal of Immunological Methods. 514, 113440.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Neutralizing Antibodies 67%
  • Antibody Formation 60%
  • Immunoglobulin G 51%
  • Immunoassay 47%

• Neutralizing activity and 3-month durability of tixagevimab and cilgavimab prophylaxis against Omicron sublineages in transplant recipients

  Karaba, A. H., Kim, J. D., Chiang, T. P. Y., Alejo, J. L., Sitaras, I., Abedon, A. T., Eby, Y., Johnston, T. S., Li, M., Aytenfisu, T., Hussey, C., Jefferis, A., Fortune, N., Abedon, R., Thomas, L., Habtehyimer, F., Ruff, J., Warren, D. S., Avery, R. K., Clarke, W. A., & 5 othersPekosz, A., Massie, A. B., Tobian, A. A. R., Segev, D. L. & Werbel, W. A., Mar 2023, In: American Journal of Transplantation. 23, 3, p. 423-428 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transplant Recipients 100%
  • Neutralizing Antibodies 71%
  • Transplants 67%
  • Severe Acute Respiratory Syndrome 46%
  • Viruses 35%

• New Immunoassays in Therapeutic Drug Monitoring: Where is the Journey Heading?

  Salamone, S. J., Courtney, J. B. & Clarke, W. A., Feb 1 2023, In: Therapeutic drug monitoring. 45, 1, p. 11-13 3 p.

  Research output: Contribution to journal › Editorial › peer-review

• Persistent SARS-CoV-2–specific immune defects in kidney transplant recipients following third mRNA vaccine dose

  CPAT investigators, Jun 2023, In: American Journal of Transplantation. 23, 6, p. 744-758 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Transplant Recipients 62%
  • Vaccines 50%
  • Messenger RNA 38%
  • Kidney 36%

• Population-level analysis of natural control of HIV infection in Zambia and South Africa: HPTN 071 (PopART)

  for the HPTN 071 (PopART) Study Team, Oct 2023, In: Journal of the International AIDS Society. 26, 10, e26179.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zambia 100%
  • demographic situation 84%
  • South Africa 77%
  • HIV Infections 65%
  • Republic of South Africa 54%

• SARS-CoV-2 Antibody Prevalence among Industrial Livestock Operation Workers and Nearby Community Residents, North Carolina, 2021 to 2022

  Gigot, C., Pisanic, N., Kruczynski, K., Rivera, M. G., Spicer, K., Kurowski, K. M., Randad, P., Koehler, K., Clarke, W. A., Holmes, P., Hall, D. J., Hall, D. J. & Heaney, C. D., Jan 2023, In: mSphere. 8, 1

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Livestock 82%
  • Coronavirus 54%
  • Occupational Groups 48%
  • Antibodies 37%

• The VALIDity of Laboratory Developed Tests: Leave it to the experts?

  Marzinke, M. A., Clarke, W., Dietzen, D. J., Hoofnagle, A. N., McMillin, G. A. & Willrich, M. A. V., Jan 2023, In: Journal of Mass Spectrometry and Advances in the Clinical Lab. 27, p. 1-6 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2022

  Antiretroviral Drug Detection in a Community-Randomized Trial of Universal HIV Testing and Treatment: HPTN 071 (PopART)

  for the HPTN 071 (PopART) Study Team, Nov 1 2022, In: Open Forum Infectious Diseases. 9, 11, ofac576.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • HIV 100%
  • Pharmaceutical Preparations 60%
  • Therapeutics 23%
  • Zambia 15%
  • Confidence Intervals 13%

• Heterologous Ad.26.COV2.S versus homologous BNT162b2/mRNA-1273 as a third dose in solid organ transplant recipients seronegative after two-dose mRNA vaccination

  Chiang, T. P. Y., Alejo, J. L., Mitchell, J., Kim, J. D., Abedon, A. T., Karaba, A. H., Thomas, L., Levan, M. L., Garonzik-Wang, J. M., Avery, R. K., Pekosz, A., Clarke, WA., Warren, D. S., Tobian, A. A. R., Massie, AB., Segev, D. L. & Werbel, W. A., Sep 2022, In: American Journal of Transplantation. 22, 9, p. 2254-2260 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transplant Recipients 100%
  • Vaccination 86%
  • Transplants 67%
  • Messenger RNA 61%
  • SARS Virus 52%

• HIV drug resistance in a community-randomized trial of universal testing and treatment: HPTN 071 (PopART)

  for the HPTN 071 (PopART) Study Team, Jul 2022, In: Journal of the International AIDS Society. 25, 7, e25941.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drug Resistance 100%
  • HIV 75%
  • drug 74%
  • Reverse Transcriptase Inhibitors 26%
  • Pharmaceutical Preparations 18%

• IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function

  Casciola-Rosen, L., Thiemann, D. R., Andrade, F., Trejo-Zambrano, M. I., Leonard, E. K., Spangler, J. B., Skinner, N. E., Bailey, J., Yegnasubramanian, S., Wang, R., Vaghasia, A. M., Gupta, A., Cox, A. L., Ray, S. C., Linville, R. M., Guo, Z., Searson, P. C., Machamer, C. E., Desiderio, S., Sauer, L., & 18 othersLaeyendecker, O. B., Garibaldi, B. T., Gao, L., Damarla, M., Hassoun, P. M., Hooper, J., Mecoli, C. A., Christopher-Stine, L., Gutierrez-Alamillo, L., Yang, Q., Hines, D., Clarke, W. A., Rothman, R. E., Pekosz, A., Fenstermacher, K. Z. J., Wang, Z., Zeger, S. L. & Rosen, A., May 9 2022, In: JCI Insight. 7, 9, e158362.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • angiotensin converting enzyme 2 100%
  • anti-IgM 83%
  • Autoantibodies 62%
  • Immunoglobulin M 39%
  • Blood Vessels 39%

• Liquid chromatography–tandem mass spectrometry for clinical diagnostics

  Thomas, S. N., French, D., Jannetto, P. J., Rappold, B. A. & Clarke, W. A., Dec 2022, In: Nature Reviews Methods Primers. 2, 1, 96.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mass Spectrometry 100%
  • Liquid 59%
  • Tandem Mass Spectrometry 40%
  • Application 34%
  • Medicine 27%

• Magnetofluidic immuno-PCR for point-of-care COVID-19 serological testing

  Zhang, P., Chen, L., Hu, J., Trick, A. Y., Chen, F. E., Hsieh, K., Zhao, Y., Coleman, B., Kruczynski, K., Pisanic, T. R., Heaney, C. D., Clarke, W. A. & Wang, T. H., Jan 1 2022, In: Biosensors and Bioelectronics. 195, 113656.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus 100%
  • Assays 92%
  • Point-of-Care Systems 89%
  • Antibodies 75%
  • Immunoassay 74%

• Multiple Infection and Human Immunodeficiency Virus Superinfection Among Persons who Inject Drugs in Indonesia and Ukraine

  Palumbo, P. J., Grant-McAuley, W., Grabowski, M. K., Zhang, Y., Richardson, P., Piwowar-Manning, E., Sharma, D., Clarke, W., Laeyendecker, O., Rose, S., Ha, T. V., Dumchev, K., Djoerban, Z., Redd, A., Hanscom, B., Hoffman, I., Miller, W. C. & Eshleman, S. H., Dec 15 2022, In: Journal of Infectious Diseases. 226, 12, p. 2181-2191 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ukraine 100%
  • Superinfection 93%
  • Indonesia 85%
  • HIV 49%
  • Infections 34%

• National Landscape of Human Immunodeficiency Virus-Positive Deceased Organ Donors in the United States

  Werbel, W. A., Brown, D. M., Kusemiju, O. T., Doby, B. L., Seaman, S. M., Redd, A., Eby, Y., Fernandez, R. E., Desai, N., Miller, J., Bismut, G. A., Kirby, C. S., Schmidt, H. A., Clarke, W. A., Seisa, M., Petropoulos, C. J., Quinn, T. C., Florman, S. S., Huprikar, S., Rana, M. M., & 95 othersFriedman-Moraco, R. J., Mehta, A. K., Stock, P. G., Price, J. C., Stosor, V., Mehta, S. G., Gilbert, A. J., Elias, N., Morris, M. I., Mehta, S. A., Small, C. B., Haidar, G., Malinis, M., Husson, J. S., Pereira, M. R., Gupta, G., Hand, J., Kirchner, V. A., Agarwal, A., Aslam, S., Blumberg, E. A., Wolfe, C. R., Myer, K., Patrick Wood, R., Neidlinger, N., Strell, S., Shuck, M., Wilkins, H., Wadsworth, M., Motter, J. D., Odim, J., Segev, D., Durand, C. M., Tobian, A. A. R., Piquant, D., Link, K., Hemmersbach-Miller, M., Pearson, T., Turgeon, N., Lyon, G. M., Kitchens, W., Huckaby, J., Lasseter, A. F., Elbein, R., Roberson, A., Ferry, E., Klock, E., Cochran, W. V., Morrison, M., Rasmussen, S., Bollinger, J., Sugarman, J., Smith, A. R., Thomas, M., Coakley, M., Timpone, J., Stucke, A., Haydel, B., Dieter, R., Klein, E. J., Neumann, H., Gallon, L., Goudy, L., Callegari, M., Marrazzo, I., Jackson, T., Pruett, T., Farnsworth, M., Locke, J. E., Mompoint-Williams, D., Basinger, K., Mekeel, K., Nguyen, P., Kwan, J., Srisengfa, T., Chin-Hong, P., Rogers, R., Simkins, J., Munoz, C., Dunn, T., Sawinski, D., Silveira, F., Hughes, K., Pakstis, D. L., Nagy, J., Baldecchi, M., Muthukumar, T., Eddie, M. D., Robb, K., Salsgiver, E., Witting, B., Azar, M. M., Villanueva, M., Formica, R. & Tomlin, R., Jun 1 2022, In: Clinical Infectious Diseases. 74, 11, p. 2010-2019 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tissue Donors 100%
  • HIV 87%
  • Integrases 17%
  • Viral Load 12%
  • T-Lymphocytes 12%

• Prognostic Significance of Urinary Biomarkers in Patients Hospitalized With COVID-19

  the TRIKIC Consortium Investigators, Feb 2022, In: American Journal of Kidney Diseases. 79, 2, p. 257-267.e1

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus 100%
  • Biomarkers 51%
  • Acute Kidney Injury 45%
  • Kidney 25%
  • Kidney Diseases 16%

• Routine Antiretroviral Pharmacy Refill Information Can Predict Failure Postpartum in Previously Suppressed South African Women With HIV

  Gawler, N., Reynolds, S. J., Hsiao, N. Y., Clarke, W., Maartens, G., Abrams, E. J., Myer, L., Redd, A. D. & Phillips, T. K., Oct 1 2022, In: Open Forum Infectious Diseases. 9, 10, ofac483.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pharmacy 100%
  • Postpartum Period 94%
  • HIV 68%
  • Viral Load 54%
  • Odds Ratio 45%

• Validation of a lateral flow chromatographic immunoassay for the detection of fentanyl in drug samples

  Park, J. N., Sherman, S. G., Sigmund, V., Breaud, A., Martin, K. & Clarke, W. A., Nov 1 2022, In: Drug and alcohol dependence. 240, 109610.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fentanyl 100%
  • Immunoassay 67%
  • Flow 43%
  • Drug 35%
  • Pharmaceutical Preparations 28%
• 2021

  Characterization of drug binding with alpha₁-acid glycoprotein in clinical samples using ultrafast affinity extraction

  Beeram, S. R., Zhang, C., Suh, K., Clarke, W. A. & Hage, D. S., Jul 19 2021, In: Journal of Chromatography A. 1649, 462240.

  Research output: Contribution to journal › Article › peer-review

  • Glycoprotein 100%
  • Glycoproteins 92%
  • Acids 82%
  • Drug 57%
  • Pharmaceutical Preparations 45%

• Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers

  Patel, E. U., Bloch, E. M., Clarke, W., Hsieh, Y. H., Boon, D., Eby, Y., Fernandez, R. E., Baker, O. R., Keruly, M., Kirby, C. S., Klock, E., Littlefield, K., Miller, J., Schmidt, H. A., Sullivan, P., Piwowar-Manning, E., Shrestha, R., Redd, A. D., Rothman, R. E., Sullivan, D., & 6 othersShoham, S., Casadevall, A., Quinn, T. C., Pekosz, A., Tobian, A. A. R. & Laeyendecker, O., Feb 2021, In: Journal of clinical microbiology. 59, 2, e02257-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Immunoenzyme Techniques 79%
  • Antibodies 42%
  • Tissue Donors 30%
  15 Scopus citations

• COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva

  Pisanic, N., Randad, P. R., Kruczynski, K., Manabe, Y. C., Thomas, D. L., Pekosz, A., Klein, S. L., Betenbaugh, M. J., Clarke, W. A., Laeyendecker, O., Caturegli, P. P., Benjamin Larman, H., Detrick, B., Fairley, J. K., Sherman, A. C., Rouphael, N., Edupuganti, S., Granger, D. A., Granger, S. W., Collins, M. H., & 1 othersHeaney, C. D., Jan 2021, In: Journal of clinical microbiology. 59, 1, e02204-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Serology 82%
  • Antibody Formation 69%
  • Immunoglobulin G 36%
  16 Scopus citations

• Demographic and clinical correlates of acute and convalescent SARS-CoV-2 infection among patients of a U.S. emergency department

  Johns Hopkins COVID-19 EM Investigators, Oct 2021, In: American Journal of Emergency Medicine. 48, p. 261-268 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Hospital Emergency Service 54%
  • Demography 43%
  • Polymerase Chain Reaction 35%
  • Antibodies 32%

• Depressive symptoms and use of HIV care and medication-assisted treatment among people with HIV who inject drugs

  Zeziulin, O., Mollan, K. R., Shook-Sa, B. E., Hanscom, B., Lancaster, K. E., Dumchev, K., Go, V. F., Chu, V. A., Kiriazova, T., Syarif, Z., Dvoryak, S., Reifeis, S. A., Hamilton, E., Sarasvita, R., Rose, S., Richardson, P., Clarke, W., Latkin, C. A., Metzger, D. S., Hoffman, I. F., & 1 othersMiller, W. C., Mar 1 2021, In: AIDS. 35, 3, p. 495-501 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • HIV 100%
  • Ukraine 75%
  • Vietnam 64%
  • Indonesia 63%
  • Pharmaceutical Preparations 60%

• Differential performance of coronachek sars-cov-2 lateral flow antibody assay by geographic origin of samples

  Baker, O. R., Grabowski, M. K., Galiwango, R. M., Nalumansi, A., Serwanga, J., Clarke, W., Hsieh, Y. H., Rothman, R. E., Fernandez, R. E., Serwadda, D., Kagaayi, J., Lutalo, T., Reynolds, S. J., Kaleebu, P., Quinn, T. C. & Laeyendecker, O., Jul 2021, In: Journal of clinical microbiology. 59, 7, e00837-21.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Baltimore 100%
  • Confidence Intervals 66%
  • Antibodies 61%
  • Uganda 52%
  • Polymerase Chain Reaction 19%

• Early Development and Durability of SARS-CoV-2 Antibodies Among Solid Organ Transplant Recipients: A Pilot Study

  Boyarsky, B. J., Ou, M. T., Werbel, W. A., Avery, R. K., Clarke, W. A., Tobian, A. A. R., Massie, A. B., Segev, D. L. & Garonzik Wang, J. M., May 1 2021, In: Transplantation. 105, 5, p. E52-E53

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  3 Scopus citations

• Evaluation of multi-assay algorithms for identifying individuals with recent HIV infection: HPTN 071 (PopART)

  Grant-McAuley, W., Klock, E., Laeyendecker, O., Piwowar-Manning, E., Wilson, E., Clarke, W., Breaud, A., Moore, A., Ayles, H., Kosloff, B., Shanaube, K., Bock, P., Mandla, N., van Deventer, A., Fidler, S., Donnell, D., Hayes, R. & Eshleman, S. H., Dec 2021, In: PloS one. 16, 12 December, e0258644.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • HIV Infections 100%
  • HIV 31%
  • Viral Load 21%
  • Point-of-Care Systems 12%
  • Infections 10%

• Evaluation of serological SARS-CoV-2 lateral flow assays for rapid point-of-care testing

  Conklin, S. E., Martin, K., Manabe, Y. C., Schmidt, H. A., Miller, J., Keruly, M., Klock, E., Kirby, C. S., Baker, O. R., Fernandez, R. E., Eby, Y. J., Hardick, J., Shaw-Saliba, K., Rothman, R. E., Caturegli, P. P., Redd, A. D., Tobian, A. A. R., Bloch, E. M., Benjamin Larman, H., Quinn, T. C., & 2 othersClarke, W. & Laeyendecker, O., Feb 2021, In: Journal of clinical microbiology. 59, 2, e02020-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Point-of-Care Testing 100%
  • Severe Acute Respiratory Syndrome 94%
  • Coronavirus 92%
  • Immunoglobulin M 65%
  • Immunoglobulin G 44%
  4 Scopus citations

• Multi-Site Evaluation of Immunoassays for Antipsychotic Drug Measurement in Clinical Samples

  Clarke, W. A., Salyer, B., Hussey, C., Gardiner, J. A., Johnson-Davis, K. & Milone, M. C., Nov 1 2021, In: Journal of Applied Laboratory Medicine. 6, 6, p. 1541-1550 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroleptic Agent 100%
  • Assays 85%
  • Immunoassay 73%
  • Antipsychotic Agents 67%
  • Drug Monitoring 42%

• Pathology Residency Program Special Expertise Tracks Meet the Needs of an Evolving Field

  Wake, L. M., Allison, D. B., Ware, A. D., Hooper, J. E., Baras, A. S., Bloch, E. M., Clarke, W., Burns, K. H., Sfanos, K. S., Borowitz, M. J., Steenbergen, C., Hruban, R. H. & White, M. J., 2021, In: Academic Pathology. 8

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Internship and Residency 100%
  • Curriculum 94%
  • Informatics 91%
  • Global Health 70%
  • Pathology 60%

• Rapid Quantification of Plasma Creatinine Using a Novel Kinetic Enzymatic Assay

  Jimenez Valencia, A. M., Kryszak, L. A., Goheen, J., Van Roy, W., Woronoff, G., Mathieu, E., Gudjonsdottir, H., Stakenborg, T. & Clarke, W. A., May 1 2021, In: The journal of applied laboratory medicine. 6, 3, p. 688-701 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcosine Oxidase 100%
  • Sarcosine 66%
  • Oxidoreductases 60%
  • Creatinine 60%
  • Assays 58%

• The Clinical Review Committee: Impact of the Development of in Vitro Diagnostic Tests for SARS-CoV-2 within RADx Tech

  Robinson, M., Gaydos, C., Van Der Pol, B., McFall, S., Hsieh, Y. H., Clarke, W., Murphy, R., Widdice, L., Hirschhorn, L., Rothman, R., Achenbach, C., Hawkins, C., Samuta, A., Gibson, L., McManus, D. & Manabe, Y., 2021, In: IEEE Open Journal of Engineering in Medicine and Biology. 2, p. 138-141 4 p., 9418532.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Containment of Biohazards 100%
  • Clinical laboratories 87%
  • Feedback 72%
  • Supply chains 56%
  • Industry 49%

• The HIV Screening Cascade: Current Emergency Department-Based Screening Strategies Leave Many Patients with HIV Undiagnosed

  Mohareb, A. M., Patel, A. V., Laeyendecker, O. B., Toerper, M. F., Signer, D., Clarke, W. A., Kelen, G. D., Quinn, T. C., Haukoos, J. S., Rothman, R. E. & Hsieh, Y. H., May 1 2021, In: Journal of Acquired Immune Deficiency Syndromes. 87, 1, p. E167-E169

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Therapeutic drug monitoring in oncology: International Association of Therapeutic Drug Monitoring and Clinical Toxicology consensus guidelines for imatinib therapy

  Clarke, W. A., Chatelut, E., Fotoohi, A. K., Larson, R. A., Martin, J. H., Mathijssen, R. H. J. & Salamone, S. J., Nov 2021, In: European Journal of Cancer. 157, p. 428-440 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Drug Monitoring 100%
  • Imatinib Mesylate 98%
  • Toxicology 84%
  • Consensus 82%
  • Guidelines 55%

• Uptake of antiretroviral treatment and viral suppression among men who have sex with men and transgender women in sub-Saharan Africa in an observational cohort study: HPTN 075

  Palumbo, P. J., Zhang, Y., Clarke, W., Breaud, A., Sivay, M., Cummings, V., Hamilton, E. L., Guo, X., Ogendo, A., Kayange, N., Panchia, R., Dominguez, K., Chen, Y. Q., Sandfort, T. G. M. & Eshleman, S. H., Mar 2021, In: International Journal of Infectious Diseases. 104, p. 465-470 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Africa South of the Sahara 83%
  • Sexual and Gender Minorities 77%
  • Observational Studies 58%
  • Cohort Studies 51%
  • Viral Drug Resistance 48%
• 2020

  Analysis of Busulfan in Plasma by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

  Pablo, A., Breaud, A. R. & Clarke, W., Jun 1 2020, In: Current Protocols in Toxicology. 84, 1, e93.

  Research output: Contribution to journal › Article › peer-review

  • Busulfan 100%
  • Tandem Mass Spectrometry 62%
  • Liquid Chromatography 59%
  • Plasma 35%
  • Precision Medicine 20%

• Analysis of Immunosuppressant Drugs in Whole Blood by Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS)

  Pablo, A. H., Breaud, A. R. & Clarke, W., Jun 1 2020, In: Current Protocols in Toxicology. 84, 1, e92.

  Research output: Contribution to journal › Article › peer-review

  • Immunosuppressive Agent 100%
  • Mass Spectrometry 68%
  • Everolimus 65%
  • Immunosuppressive Agents 62%
  • Sirolimus 61%

• Analytical description of the lag phase in coupled-enzyme substrate assays

  Van Roy, W., Woronoff, G., Jimenez Valencia, A. M., Stakenborg, T. & Clarke, W. A., Sep 15 2020, In: Biochemical Engineering Journal. 161, 107699.

  Research output: Contribution to journal › Article › peer-review

  • Assays 100%
  • Enzymes 98%
  • Enzyme Assays 97%
  • Vmax 93%
  • assay 73%
  1 Scopus citations

• An assessment of the limits of detection, sensitivity and specificity of three devices for public health-based drug checking of fentanyl in street-acquired samples

  Green, T. C., Park, J. N., Gilbert, M., McKenzie, M., Struth, E., Lucas, R., Clarke, W. & Sherman, S. G., Mar 2020, In: International Journal of Drug Policy. 77, 102661.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fentanyl 100%
  • Limit of Detection 97%
  • Sensitivity and Specificity 68%
  • public health 67%
  • Public Health 65%
  21 Scopus citations

• Antiretroviral adherence, elevated viral load, and drug resistance mutations in human immunodeficiency virus-infected women initiating treatment in Pregnancy: A nested case-control study

  Myer, L., Redd, A. D., Mukonda, E., Lynch, B. A., Phillips, T. K., Eisenberg, A., Hsiao, N. Y., Capoferri, A., Zerbe, A., Clarke, W., Lesosky, M., Breaud, A., McIntyre, J., Bruno, D., Martens, C., Abrams, E. J. & Reynolds, S. J., Feb 1 2020, In: Clinical Infectious Diseases. 70, 3, p. 501-508 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Viral Drug Resistance 100%
  • Viral Load 60%
  • Case-Control Studies 50%
  • HIV 43%
  • Pregnancy 37%
  5 Scopus citations

• Antiretroviral drug use and HIV drug resistance in female sex workers in Tanzania and the Dominican Republic

  Grant-McAuley, W., Fogel, J. M., Galai, N., Clarke, W., Breaud, A., Marzinke, M. A., Mbwambo, J., Likindikoki, S., Aboud, S., Donastorg, Y., Perez, M., Barrington, C., Davis, W., Kerrigan, D. & Eshleman, S. H., Oct 2020, In: PloS one. 15, 10 October, e0240890.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dominican Republic 100%
  • Sex Workers 82%
  • Tanzania 79%
  • Drug Resistance 60%
  • HIV 45%

• ART adherence, resistance, and long-term HIV viral suppression in postpartum women

  Redd, A. D., Mukonda, E., Hu, N. C., Philips, T. K., Zerbe, A., Lesosky, M., Hsiao, N. Y., Clarke, W., Reynolds, S. J., Abrams, E. J. & Myer, L., Oct 1 2020, In: Open Forum Infectious Diseases. 7, 10

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Postpartum Period 100%
  • Drug Resistance 96%
  • HIV 72%
  • Mutation 58%
  • Viral Load 50%

• Automated analysis of dried urine spot (DUS) samples for toxicology screening

  Pablo, A., Breaud, A. R. & Clarke, W., Jan 2020, In: Clinical Biochemistry. 75, p. 70-77 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Toxicology 100%
  • Urine 73%
  • Robotics 62%
  • Filter Paper 59%
  • Liquid 55%
  1 Scopus citations

• Cancer Chemotherapy: The Case for Therapeutic Drug Monitoring

  Knezevic, C. E. & Clarke, W., Feb 1 2020, In: Therapeutic drug monitoring. 42, 1, p. 6-19 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Drug Monitoring 100%
  • Drug Therapy 50%
  • Antineoplastic Combined Chemotherapy Protocols 48%
  • Pharmaceutical Preparations 35%
  • Body Surface Area 32%
  1 Scopus citations

• Development of a microcolumn one-site immunometric assay for a protein biomarker: Analysis of alpha₁-acid glycoprotein

  Zhang, C., Lott, S., Clarke, W. & Hage, D. S., Jan 11 2020, In: Journal of Chromatography A. 1610, 460558.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glycoprotein 100%
  • Biological Marker 98%
  • Glycoproteins 92%
  • Acids 82%
  • Biomarkers 70%