William B Guggino

Professor & Director

1973 …2018
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Research Output 1973 2018

Rescue of CFTR NBD2 mutants N1303K and S1235R is influenced by the functioning of the autophagosome

Liu, Q., Sabirzhanova, I., Yanda, M. K., Bergbower, E. A. S., Boinot, C., Guggino, W. B. & Cebotaru, L., Jan 1 2018, (Accepted/In press) In : Journal of Cystic Fibrosis.

Research output: Contribution to journalArticle

Cystic Fibrosis
Mutation
Cysteine Proteinase Inhibitors
Chloride Channels
Autophagy

The CFTR-Associated ligand arrests the trafficking of the mutant Δf508 CFTR channel in the ER contributing to cystic fibrosis

Bergbower, E., Boinot, C., Sabirzhanova, I., Guggino, W. & Cebotaru, L., Feb 1 2018, In : Cellular Physiology and Biochemistry. 45, 2, p. 639-655 17 p.

Research output: Contribution to journalArticle

Cystic Fibrosis
Endoplasmic Reticulum
Ligands
PDZ Domains
Proteins

Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields

Krishnan, V., Park, S. A., Shin, S. S., Alon, L., Tressler, C. M., Stokes, W., Banerjee, J., Sorrell, M. E., Tian, Y., Fridman, G. Y., Celnik, P., Pevsner, J., Guggino, W. B., Gilad, A. A. & Pelled, G., Dec 1 2018, In : Scientific Reports. 8, 1, 8764

Research output: Contribution to journalArticle

Electromagnetic Fields
Electromagnetic Phenomena
Genes
Proteins
Avoidance Learning
Gene therapy
Dependovirus
Viruses
Cystic Fibrosis
Genetic Therapy

A Preclinical Study in Rhesus Macaques for Cystic Fibrosis to Assess Gene Transfer and Transduction by AAV1 and AAV5 with a Dual-Luciferase Reporter System

Guggino, W. B., Benson, J., Seagrave, J. C., Yan, Z., Engelhardt, J., Gao, G., Conlon, T. J. & Cebotaru, L., Sep 1 2017, In : Human gene therapy. Clinical development. 28, 3, p. 145-156 12 p.

Research output: Contribution to journalArticle

Macaca mulatta
Luciferases
Cystic Fibrosis
Genetic Therapy
Lung