Wenzhen Duan

Associate Professor

19962019
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Research Output 1996 2019

2019

Brain structure in juvenile-onset Huntington disease

Tereshchenko, A., Magnotta, V., Epping, E., Mathews, K., Espe-Pfeifer, P., Martin, E., Dawson, J., Duan, W. & Nopoulos, P., Apr 23 2019, In : Neurology. 92, 17, p. e1939-e1947

Research output: Contribution to journalArticle

Open Access
Huntington Disease
Brain
Cerebellum
Phenotype
Corpus Striatum

Differential Changes in Functional Connectivity of Striatum-Prefrontal and Striatum-Motor Circuits in Premanifest Huntington's Disease

Kronenbuerger, M., Hua, J., Bang, J. Y. A., Ultz, K. E., Miao, X., Zhang, X., Pekar, J. J., Van Zijl, P. C., Duan, W., Margolis, R. L. & Ross, C. A., Jan 1 2019, (Accepted/In press) In : Neurodegenerative Diseases.

Research output: Contribution to journalArticle

Huntington Disease
Networks (circuits)
Motor Cortex
Cytosine
Guanine
2018

Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease

Zhou, X., Li, G., Kaplan, A., Gaschler, M. M., Zhang, X., Hou, Z., Jiang, M., Zott, R., Cremers, S., Stockwell, B. R. & Duan, W., May 1 2018, In : Human Molecular Genetics. 27, 9, p. 1545-1555 11 p.

Research output: Contribution to journalArticle

Protein Disulfide-Isomerases
Endoplasmic Reticulum Stress
Huntington Disease
Brain
Endoplasmic Reticulum
2017

2,4 DNP improves motor function, preserves medium spiny neuronal identity, and reduces oxidative stress in a mouse model of Huntington's disease

Wu, B., Jiang, M., Peng, Q., Li, G., Hou, Z., Milne, G. L., Mori, S., Alonso, R., Geisler, J. G. & Duan, W., Jul 1 2017, In : Experimental Neurology. 293, p. 83-90 8 p.

Research output: Contribution to journalArticle

2,4-Dinitrophenol
Huntington Disease
Oxidative Stress
Proton Ionophores
F2-Isoprostanes

Mechanisms underlying neurodegeneration in Huntington disease: applications to novel disease-modifying therapies

Ross, C. A., Kronenbuerger, M., Duan, W. & Margolis, R. L., Jan 1 2017, Handbook of Clinical Neurology. Elsevier B.V., Vol. 144. p. 15-28 14 p. (Handbook of Clinical Neurology; vol. 144).

Research output: Chapter in Book/Report/Conference proceedingChapter

Huntington Disease
Therapeutics
Antisense RNA
Mutant Proteins
Post Translational Protein Processing

Mutant Huntingtin Disrupts the Nuclear Pore Complex

Grima, J. C., Daigle, J. G., Arbez, N., Cunningham, K. C., Zhang, K., Ochaba, J., Geater, C., Morozko, E., Stocksdale, J., Glatzer, J. C., Pham, J. T., Ahmed, I., Peng, Q., Wadhwa, H., Pletnikova, O., Troncoso, J. C., Duan, W., Snyder, S. H., Ranum, L. P. W., Thompson, L. M. & 3 others, Lloyd, T., Ross, C. A. & Rothstein, J. D., Apr 5 2017, In : Neuron. 94, 1, p. 93-107.e6

Research output: Contribution to journalArticle

Nuclear Pore
Nuclear Pore Complex Proteins
Cell Nucleus Active Transport
Huntington Disease
Neurons

Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats

Ratovitski, T., O'Meally, R. N., Jiang, M., Chaerkady, R., Chighladze, E., Stewart, J. C., Wang, X., Arbez, N., Roby, E., Alexandris, A., Duan, W., Vijayvargia, R., Seong, I. S., Lavery, D. J., Cole, R. N. & Ross, C. A., Aug 4 2017, In : Journal of Proteome Research. 16, 8, p. 2692-2708 17 p.

Research output: Contribution to journalArticle

Post Translational Protein Processing
Mass spectrometry
Huntington Disease
Brain
Phospho-Specific Antibodies

Resting-state functional MRI reveals altered brain connectivity and its correlation with motor dysfunction in a mouse model of Huntington's disease

Li, Q., Li, G., Wu, D., Lu, H., Hou, Z., Ross, C. A., Yang, Y., Zhang, J. & Duan, W., Dec 1 2017, In : Scientific Reports. 7, 1, 16742.

Research output: Contribution to journalArticle

Huntington Disease
Magnetic Resonance Imaging
Brain
Atrophy
Corpus Striatum
2016

Characterization of behavioral, neuropathological, brain metabolic and key molecular changes in zQ175 knock-in mouse model of huntington's disease

Peng, Q., Wu, B., Jiang, M., Jin, J., Hou, Z., Zheng, J., Zhang, J. & Duan, W., Feb 1 2016, In : PLoS One. 11, 2, e0148839.

Research output: Contribution to journalArticle

Huntington Disease
Brain
animal models
brain
mice

Metformin Protects Cells from Mutant Huntingtin Toxicity Through Activation of AMPK and Modulation of Mitochondrial Dynamics

Jin, J., Gu, H., Anders, N., Ren, T., Jiang, M., Tao, M., Peng, Q., Rudek-Renaut, M. & Duan, W., May 25 2016, (Accepted/In press) In : NeuroMolecular Medicine. p. 1-12 12 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
AMP-Activated Protein Kinases
Metformin
Huntington Disease
Caloric Restriction

The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect

Chu, S., Liu, S., Duan, W., Cheng, Y., Jiang, X., Zhu, C., Tang, K., Wang, R., Xu, L., Wang, X., Yu, X., Wu, K., Wang, Y., Wang, M., Huang, H. & Zhang, J., Jun 1 2016, In : Pharmacology and Therapeutics. 162, p. 179-187 9 p.

Research output: Contribution to journalArticle

Dementia
Pharmaceutical Preparations
Cognition
clausenamide
Nootropic Agents
2015

Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease

Jin, J., Peng, Q., Hou, Z., Jiang, M., Wang, X., Langseth, A. J., Tao, M., Barker, P. B., Mori, S., Bergles, D. E., Ross, C. A., Detloff, P. J., Zhang, J. & Duan, W., 2015, In : Human Molecular Genetics. 24, 9, p. 2508-2527 20 p.

Research output: Contribution to journalArticle

Huntington Disease
Pathology
Corpus Striatum
Brain
Myelin Sheath
2014

Metabolism in HD: Still a relevant mechanism?

Duan, W., Jiang, M. & Jin, J., Sep 15 2014, In : Movement disorders : official journal of the Movement Disorder Society. 29, 11, p. 1366-1374 9 p.

Research output: Contribution to journalArticle

Huntington Disease
Energy Metabolism
Corpus Striatum
Inborn Genetic Diseases
Central Nervous System Diseases

Sirtuin 1 activator SRT2104 protects Huntington's disease mice

Jiang, M., Zheng, J., Peng, Q., Hou, Z., Zhang, J., Mori, S., Ellis, J. L., Vlasuk, G. P., Fries, H., Suri, V. & Duan, W., Dec 1 2014, In : Annals of Clinical and Translational Neurology. 1, 12, p. 1047-1052 6 p.

Research output: Contribution to journalArticle

Sirtuin 1
Huntington Disease
Neurodegenerative Diseases
NAD
Atrophy
2013

Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease

Jin, J., Albertz, J., Guo, Z., Peng, Q., Rudow, G., Troncoso, J. C., Ross, C. A. & Duan, W., May 2013, In : Journal of Neurochemistry. 125, 3, p. 410-419 10 p.

Research output: Contribution to journalArticle

rosiglitazone
Peroxisome Proliferator-Activated Receptors
Huntington Disease
Neuroprotective Agents
Neurodegenerative diseases

Sirtuins: From metabolic regulation to brain aging

Duan, W., 2013, In : Frontiers in Aging Neuroscience. 5, JUL, article 36.

Research output: Contribution to journalArticle

Sirtuins
Brain
Neurodegenerative Diseases
Risk Reduction Behavior
Metabolic Networks and Pathways

Small-molecule TrKB receptor agonists improve motor function and extend survival in a mouse model of huntington's disease

Jiang, M., Peng, Q., Liu, X., Jin, J., Hou, Z., Zhang, J., Mori, S., Ross, C. A., Ye, K. & Duan, W., Jun 2013, In : Human Molecular Genetics. 22, 12, p. 2462-2470 9 p.

Research output: Contribution to journalArticle

Huntington Disease
Survival
Brain-Derived Neurotrophic Factor
Brain
Trinucleotide Repeat Expansion

Targeting Sirtuin-1 in Huntington's disease: Rationale and current status

Duan, W., May 2013, In : CNS Drugs. 27, 5, p. 345-352 8 p.

Research output: Contribution to journalArticle

Sirtuin 1
Huntington Disease
Trinucleotide Repeats
Inborn Genetic Diseases
Caenorhabditis elegans
2012

Activation of ERK1/2-CREB pathway during potentiating synaptic transmission of (2)clausenamide in rat dentate gyrus

Hu, J. F., Niu, F., Ning, N., Duan, W., Chu, S. F., Xue, W., Yuan, Y. H., Chen, N. H. & Zhang, J. T., 2012, In : Journal of Asian Natural Products Research. 14, 3, p. 256-262 7 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Dentate Gyrus
Synaptic Transmission
Phosphorylation

Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin

Jin, J., Cheng, Y., Zhang, Y., Wood, W., Peng, Q., Hutchison, E., Mattson, M. P., Becker, K. G. & Duan, W., Nov 2012, In : Journal of Neurochemistry. 123, 4, p. 477-490 14 p.

Research output: Contribution to journalArticle

Huntington Disease
MicroRNAs
Brain
Messenger RNA
Cerebral Cortex

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

Jiang, M., Wang, J., Fu, J., Du, L., Jeong, H., West, T., Xiang, L., Peng, Q., Hou, Z., Cai, H., Seredenina, T., Arbez, N., Zhu, S., Sommers, K., Qian, J., Zhang, J., Mori, S., Yang, X. W., Tamashiro, K., Aja, S. M. & 10 others, Moran, T. H., Luthi-Carter, R., Martin, B., Maudsley, S., Mattson, M. P., Cichewicz, R. H., Ross, C. A., Holtzman, D. M., Krainc, D. & Duan, W., Jan 2012, In : Nature Medicine. 18, 1, p. 153-158 6 p.

Research output: Contribution to journalArticle

Sirtuin 1
Huntington Disease
Chemical activation
Toxicity
Dopamine and cAMP-Regulated Phosphoprotein 32

Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging

Aggarwal, M., Duan, W., Hou, Z., Rakesh, N., Peng, Q., Ross, C. A., Miller, M. I., Mori, S. & Zhang, J., May 1 2012, In : NeuroImage. 60, 4, p. 2086-2095 10 p.

Research output: Contribution to journalArticle

Brain Mapping
Huntington Disease
Atrophy
Magnetic Resonance Imaging
Sertraline

Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease

Guo, Z., Rudow, G., Pletnikova, O., Codispoti, K. E., Orr, B. A., Crain, B. J., Duan, W., Margolis, R. L., Rosenblatt, A., Ross, C. A. & Troncoso, J. C., Sep 15 2012, In : Movement disorders : official journal of the Movement Disorder Society. 27, 11, p. 1379-1386 8 p.

Research output: Contribution to journalArticle

Corpus Striatum
Huntington Disease
Subthalamic Nucleus
Chorea
Putamen

Trans-(-)-ε-viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated Protein Kinase (AMPK), and protects cells in models of huntington disease

Fu, J., Jin, J., Cichewicz, R. H., Hageman, S. A., Ellis, T. K., Xiang, L., Peng, Q., Jiang, M., Arbez, N., Hotaling, K., Ross, C. A. & Duan, W., Jul 13 2012, In : Journal of Biological Chemistry. 287, 29, p. 24460-24472 13 p.

Research output: Contribution to journalArticle

Sirtuin 3
AMP-Activated Protein Kinases
Huntington Disease
Organelle Biogenesis
Biological Products

Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin

Waldron-Roby, E., Ratovitski, T., Wang, X., Jiang, M., Watkin, E., Arbez, N., Graham, R. K., Hayden, M. R., Hou, Z., Mori, S., Swing, D., Pletnikov, M., Duan, W., Tessarollo, L. & Ross, C. A., Jan 4 2012, In : Journal of Neuroscience. 32, 1, p. 183-193 11 p.

Research output: Contribution to journalArticle

Caspase 6
Transgenic Mice
Poisons
Huntington Disease
Prions
2011

Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease

Xiang, Z., Valenza, M., Cui, L., Leoni, V., Jeong, H. K., Brilli, E., Zhang, J., Peng, Q., Duan, W., Reeves, S. A., Cattaneo, E. & Krainc, D., Jun 29 2011, In : Journal of Neuroscience. 31, 26, p. 9544-9553 10 p.

Research output: Contribution to journalArticle

Myelin Basic Protein
Huntington Disease
Theoretical Models
Oligodendroglia
Knockout Mice

Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model

Cheng, Y., Peng, Q., Hou, Z., Aggarwal, M., Zhang, J., Mori, S., Ross, C. A. & Duan, W., Jun 1 2011, In : NeuroImage. 56, 3, p. 1027-1034 8 p.

Research output: Contribution to journalArticle

Huntington Disease
Neuroprotective Agents
Atrophy
Brain
Biomarkers
2010

Baicalein reduces E46K α-synuclein aggregation in vitro and protects cells against E46K α-synuclein toxicity in cell models of familiar Parkinsonism

Jiang, M., Porat-Shliom, Y., Pei, Z., Cheng, Y., Xiang, L., Sommers, K., Li, Q., Gillardon, F., Hengerer, B., Berlinicke, C. A., Smith, W., Zack, D. J., Poirier, M. A., Ross, C. A. & Duan, W., Jul 2010, In : Journal of Neurochemistry. 114, 2, p. 419-429 11 p.

Research output: Contribution to journalArticle

Synucleins
Parkinsonian Disorders
Toxicity
Agglomeration
Proteasome Endopeptidase Complex

Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images

Zhang, J., Peng, Q., Li, Q., Jahanshad, N., Hou, Z., Jiang, M., Masuda, N., Langbehn, D. R., Miller, M. I., Mori, S., Ross, C. A. & Duan, W., Feb 1 2010, In : NeuroImage. 49, 3, p. 2340-2351 12 p.

Research output: Contribution to journalArticle

Huntington Disease
Atrophy
Magnetic Resonance Spectroscopy
Brain
Corpus Striatum

Potential therapeutic targets for neurodegenerative diseases: Lessons learned from calorie restriction

Duan, W. & Ross, C. A., 2010, In : Current Drug Targets. 11, 10, p. 1281-1292 12 p.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Neurodegenerative Diseases
Sirtuins
Animal Disease Models
Translational Medical Research
2008

Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization

Guo, Z., Jiang, H., Xu, X., Duan, W. & Mattson, M. P., Jan 18 2008, In : Journal of Biological Chemistry. 283, 3, p. 1754-1763 10 p.

Research output: Contribution to journalArticle

Cell signaling
Leptin
Neurons
Cell Survival
Stabilization

Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease

Duan, W., Peng, Q., Masuda, N., Ford, E., Tryggestad, E., Ladenheim, B., Zhao, M., Cadet, J. L., Wong, J. & Ross, C. A., Jun 2008, In : Neurobiology of Disease. 30, 3, p. 312-322 11 p.

Research output: Contribution to journalArticle

Sertraline
Huntington Disease
Neurogenesis
Disease Progression
Brain-Derived Neurotrophic Factor

Single particle characterization of iron-induced pore-forming α-synuclein oligomers

Kostka, M., Högen, T., Danzer, K. M., Levin, J., Habeck, M., Wirth, A., Wagner, R., Glabe, C. G., Finger, S., Heinzelmann, U., Garidel, P., Duan, W., Ross, C. A., Kretzschmar, H. & Giese, A., Apr 18 2008, In : Journal of Biological Chemistry. 283, 16, p. 10992-11003 12 p.

Research output: Contribution to journalArticle

Synucleins
Oligomers
Iron
Poisons
Amyloid

The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model

Peng, Q., Masuda, N., Jiang, M., Li, Q., Zhao, M., Ross, C. A. & Duan, W., Mar 2008, In : Experimental Neurology. 210, 1, p. 154-163 10 p.

Research output: Contribution to journalArticle

Sertraline
Huntington Disease
Brain-Derived Neurotrophic Factor
Neurogenesis
Antidepressive Agents

Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease

Masuda, N., Peng, Q., Li, Q., Jiang, M., Liang, Y., Wang, X., Zhao, M., Wang, W., Ross, C. A. & Duan, W., Jun 2008, In : Neurobiology of Disease. 30, 3, p. 293-302 10 p.

Research output: Contribution to journalArticle

Huntington Disease
Blood-Brain Barrier
National Institute of Neurological Disorders and Stroke
Chorea
Cell Aggregation
2007

Bioactivity profiling with parallel mass spectrometry reveals an assemblage of green tea metabolites affording protection against human huntingtin and α-synuclein toxicity

Williams, R. B., Gutekunst, W. R., Joyner, P. M., Duan, W., Li, Q., Ross, C. A., Williams, T. D. & Cichewicz, R. H., Nov 14 2007, In : Journal of Agricultural and Food Chemistry. 55, 23, p. 9450-9456 7 p.

Research output: Contribution to journalArticle

Synucleins
green tea
Tea
Metabolites
Bioactivity

Gene expression atlas of the mouse central nervous system: Impact and interactions of age, energy intake and gender

Xu, X., Zhan, M., Duan, W., Prabhu, V., Brenneman, R., Wood, W., Firman, J., Li, H., Zhang, P., Ibe, C., Zonderman, A. B., Longo, D. L., Poosala, S., Becker, K. G. & Mattson, M. P., Nov 7 2007, In : Genome Biology. 8, 11, R234.

Research output: Contribution to journalArticle

Atlases
nervous system
Energy Intake
Transcriptome
atlas

Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models

Sredni, B., Geffen-Aricha, R., Duan, W., Albeck, M., Shalit, F., Lander, H. M., Kinor, N., Sagi, O., Albeck, A., Yosef, S., Brodsky, M., Sredni-Kenigsbuch, D., Sonino, T., Longo, D. L., Mattson, M. P. & Yadid, G., Jun 2007, In : FASEB Journal. 21, 8, p. 1870-1883 14 p.

Research output: Contribution to journalArticle

tellurium
Tellurium
disease models
Parkinson disease
Dopaminergic Neurons
2005

Compounds blocking mutant huntingtin toxicity identified using a Huntington's disease neuronal cell model

Wang, W., Duan, W., Igarashi, S., Morita, H., Nakamura, M. & Ross, C. A., Nov 2005, In : Neurobiology of Disease. 20, 2, p. 500-508 9 p.

Research output: Contribution to journalArticle

Huntington Disease
National Institute of Neurological Disorders and Stroke
Aptitude
Caspase Inhibitors
PC12 Cells
2004

Paroxetine Retards Disease Onset and Progression in Huntingtin Mutant Mice

Duan, W., Guo, Z., Jiang, H., Ladenheim, B., Xu, X., Cadet, J. L. & Mattson, M. P., Apr 2004, In : Annals of Neurology. 55, 4, p. 590-594 5 p.

Research output: Contribution to journalArticle

Paroxetine
Huntington Disease
Disease Progression
Antidepressive Agents
Neurotransmitter Agents

Prophylactic Activation of Neuroprotective Stress Response Pathways by Dietary and Behavioral Manipulations

Mattson, M. P., Duan, W., Wan, R. & Guo, Z., Jan 2004, In : NeuroRx. 1, 1, p. 111-116 6 p.

Research output: Contribution to journalArticle

Behavior Control
Brain-Derived Neurotrophic Factor
Neurons
Heat-Shock Proteins
Diet Therapy
2003

Cellular and molecular mechanisms whereby dietary restriction extends healthspan: a beneficial type of stress

Mattson, M. P., Duan, W., Wan, R. & Guo, Z., 2003, In : Advances in Cell Aging and Gerontology. 14, p. 87-103 17 p.

Research output: Contribution to journalArticle

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

Duan, W., Guo, Z., Jiang, H., Ware, M., Li, X. J. & Mattson, M. P., Mar 4 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 5, p. 2911-2916 6 p.

Research output: Contribution to journalArticle

Huntington Disease
Brain-Derived Neurotrophic Factor
Disease Progression
Glucose
Survival

Meal size and frequency affect neuronal plasticity and vulnerability to disease: Cellular and molecular mechanisms

Mattson, M. P., Duan, W. & Guo, Z., Feb 2003, In : Journal of Neurochemistry. 84, 3, p. 417-431 15 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Plasticity
Meals
Nerve Growth Factors
Fasting

Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain-derived neurotrophic factor

Duan, W., Guo, Z., Jiang, H., Ware, M. & Mattson, M. P., Jun 1 2003, In : Endocrinology. 144, 6, p. 2446-2453 8 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Insulin Resistance
Glucose
Obesity
Insulin
2002

Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease

Duan, W., Ladenheim, B., Cutler, R. G., Kruman, I. I., Cadet, J. L. & Mattson, M. P., 2002, In : Journal of Neurochemistry. 80, 1, p. 101-110 10 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Homocysteine
Folic Acid
Neurons
Parkinson Disease
Brain-Derived Neurotrophic Factor
Neurogenesis
Hippocampus
Bromodeoxyuridine
Dentate Gyrus

Folic acid and homocysteine in age-related disease

Mattson, M. P., Kruman, I. I. & Duan, W., Feb 2002, In : Ageing Research Reviews. 1, 1, p. 95-111 17 p.

Research output: Contribution to journalArticle

Homocysteine
Folic Acid
DNA Damage
Defects
Folic Acid Deficiency

How does the brain control lifespan?

Mattson, M. P., Duan, W. & Maswood, N., Apr 2002, In : Ageing Research Reviews. 1, 2, p. 155-165 11 p.

Research output: Contribution to journalArticle

Brain
Energy Metabolism
Neurons
Brain-Derived Neurotrophic Factor
Phosphatidylinositol 3-Kinase

Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior

Mattson, M. P., Chan, S. L. & Duan, W., 2002, In : Physiological Reviews. 82, 3, p. 637-672 36 p.

Research output: Contribution to journalArticle

Brain Diseases
Neurodegenerative Diseases
Diet
Brain
Genes