Wenzhen Duan

Associate Professor

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Fingerprint Dive into the research topics where Wenzhen Duan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 13 Similar Profiles
Huntington Disease Medicine & Life Sciences
Brain Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
Brain-Derived Neurotrophic Factor Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences
Neurons Chemical Compounds
Apoptosis Medicine & Life Sciences
Dopaminergic Neurons Medicine & Life Sciences

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Research Output 1996 2019

Brain structure in juvenile-onset Huntington disease

Tereshchenko, A., Magnotta, V., Epping, E., Mathews, K., Espe-Pfeifer, P., Martin, E., Dawson, J., Duan, W. & Nopoulos, P., Apr 23 2019, In : Neurology. 92, 17, p. e1939-e1947

Research output: Contribution to journalArticle

Open Access
Huntington Disease
Corpus Striatum

Differential Changes in Functional Connectivity of Striatum-Prefrontal and Striatum-Motor Circuits in Premanifest Huntington's Disease

Kronenbuerger, M., Hua, J., Bang, J. Y. A., Ultz, K. E., Miao, X., Zhang, X., Pekar, J. J., Van Zijl, P. C., Duan, W., Margolis, R. L. & Ross, C. A., Jan 1 2019, (Accepted/In press) In : Neurodegenerative Diseases.

Research output: Contribution to journalArticle

Huntington Disease
Networks (circuits)
Motor Cortex

Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease

Zhou, X., Li, G., Kaplan, A., Gaschler, M. M., Zhang, X., Hou, Z., Jiang, M., Zott, R., Cremers, S., Stockwell, B. R. & Duan, W., May 1 2018, In : Human Molecular Genetics. 27, 9, p. 1545-1555 11 p.

Research output: Contribution to journalArticle

Protein Disulfide-Isomerases
Endoplasmic Reticulum Stress
Huntington Disease
Endoplasmic Reticulum

2,4 DNP improves motor function, preserves medium spiny neuronal identity, and reduces oxidative stress in a mouse model of Huntington's disease

Wu, B., Jiang, M., Peng, Q., Li, G., Hou, Z., Milne, G. L., Mori, S., Alonso, R., Geisler, J. G. & Duan, W., Jul 1 2017, In : Experimental Neurology. 293, p. 83-90 8 p.

Research output: Contribution to journalArticle

Huntington Disease
Oxidative Stress
Proton Ionophores

Mechanisms underlying neurodegeneration in Huntington disease: applications to novel disease-modifying therapies

Ross, C. A., Kronenbuerger, M., Duan, W. & Margolis, R. L., Jan 1 2017, Handbook of Clinical Neurology. Elsevier B.V., Vol. 144. p. 15-28 14 p. (Handbook of Clinical Neurology; vol. 144).

Research output: Chapter in Book/Report/Conference proceedingChapter

Huntington Disease
Antisense RNA
Mutant Proteins
Post Translational Protein Processing