Wenbing Xie

RESEARCH ASSOCIATE

20122019
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Fingerprint Dive into the research topics where Wenbing Xie is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 16 Similar Profiles
DNA Methylation Medicine & Life Sciences
Methyltransferases Medicine & Life Sciences
Ribosomal DNA Medicine & Life Sciences
Nucleosomes Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
RNA Polymerase I Medicine & Life Sciences
rRNA Genes Medicine & Life Sciences
Chromatin Assembly and Disassembly Medicine & Life Sciences

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Research Output 2012 2019

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf V600E -Induced Tumorigenesis

Tao, Y., Kang, B., Petkovich, D. A., Bhandari, Y. R., In, J., Stein-O'Brien, G., Kong, X., Xie, W., Zachos, N., Maegawa, S., Vaidya, H., Brown, S., Yen, R-W., Shao, X., Thakor, J., Lu, Z., Cai, Y., Zhang, Y., Mallona, I., Peinado, M. A. & 6 others, Zahnow, C., Ahuja, N., Fertig, E., Issa, J. P., Baylin, S. B. & Easwaran, H., Feb 11 2019, In : Cancer cell. 35, 2, p. 315-328.e6

Research output: Contribution to journalArticle

Epigenomics
Organoids
Colon
Carcinogenesis
Clustered Regularly Interspaced Short Palindromic Repeats

Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties

Kong, X., Chen, J., Xie, W., Brown, S. M., Cai, Y., Wu, K., Fan, D., Nie, Y., Yegnasubramanian, S., Tiedemann, R. L., Tao, Y., Yen, R-W., Topper, M. J., Zahnow, C., Easwaran, H., Rothbart, S. B., Xia, L. & Baylin, S. B., Apr 15 2019, In : Cancer cell. 35, 4, p. 633-648.e7

Research output: Contribution to journalArticle

DNA Methylation
Colonic Neoplasms
Colorectal Neoplasms
Ubiquitin-Protein Ligases
Tumor Suppressor Genes

Metastasis-related methyltransferase 1 (Merm1) represses the methyltransferase activity of Dnmt3a and facilitates RNA polymerase I transcriptional elongation

Lyu, G., Zong, L., Zhang, C., Huang, X., Xie, W., Fang, J., Guan, Y., Zhang, L., Ni, T., Gu, J. & Tao, W., Jan 1 2019, In : Journal of Molecular Cell Biology. 11, 1, p. 78-90 13 p.

Research output: Contribution to journalArticle

RNA Polymerase I
Methyltransferases
Neoplasm Metastasis
Methylation
rRNA Genes

Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1

Ye, F., Kong, X., Zhang, H., Liu, Y., Shao, Z., Jin, J., Cai, Y., Zhang, R., Li, L., Zhang, Y., Liu, Y. C., Zhang, C., Xie, W., Yu, K., Ding, H., Zhao, K., Chen, S., Jiang, H., Baylin, S. B. & Luo, C., Mar 16 2018, In : ACS Chemical Biology. 13, 3, p. 772-781 10 p.

Research output: Contribution to journalArticle

Methyltransferases
Molecular Dynamics Simulation
Molecular dynamics
DNA
Computer simulation

DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk

Xie, W., Kagiampakis, I., Pan, L., Zhang, Y., Murphy, L., Tao, Y., Kong, X., Kang, B., Xia, L., Carvalho, F. L. F., Sen, S., Yen, R-W., Zahnow, C., Ahuja, N., Baylin, S. B. & Easwaran, H., Feb 12 2018, In : Cancer Cell. 33, 2, p. 309-321.e5

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Developmental Genes
Neoplasms
Epigenomics