Wade W Chien

ASSOCIATE PROFESSOR

20052019
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Hearing Loss Medicine & Life Sciences
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Cochlear Implantation Medicine & Life Sciences
Semicircular Canals Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences

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Research Output 2005 2019

AAV2.7m8 is a powerful viral vector for inner ear gene therapy

Isgrig, K., McDougald, D. S., Zhu, J., Wang, H. J., Bennett, J. & Chien, W. W., Dec 1 2019, In : Nature Communications. 10, 1, 427.

Research output: Contribution to journalArticle

gene therapy
Gene therapy
hair
ear
Inner Ear

Sex differences in HPV immunity among adults without cancer

Windon, M. J., Waterboer, T., Hillel, A. T., Chien, W. W., Best, S. R., Stewart, C., Akst, L. M., Troy, T., Bender, N., Miles, B., Ryan, W. R., Mandal, R., Pitman, K., Eisele, D. W., Fakhry, C. & D'Souza, G., Jan 1 2019, In : Human Vaccines and Immunotherapeutics.

Research output: Contribution to journalArticle

Seroepidemiologic Studies
Sex Characteristics
Sexual Partners
Immunity
Neoplasms

Surgical methods for inner ear gene delivery in neonatal mouse

Isgrig, K. & Chien, W. W., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 221-226 6 p. (Methods in Molecular Biology; vol. 1937).

Research output: Chapter in Book/Report/Conference proceedingChapter

Inner Ear
Genetic Therapy
Genes
Ear Round Window
Semicircular Canals

A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration

Mookherjee, S., Chen, H. Y., Isgrig, K., Yu, W., Hiriyanna, S., Levron, R., Li, T., Colosi, P., Chien, W. W., Swaroop, A. & Wu, Z., Oct 16 2018, In : Cell Reports. 25, 3, p. 611-623.e6

Research output: Contribution to journalArticle

Retinal Degeneration
Leber Congenital Amaurosis
Gene therapy
Mutation
Fibroblasts

A CRISPR way to restore hearing

Chien, W. W., Mar 29 2018, In : New England Journal of Medicine. 378, 13, p. 1255-1256 2 p.

Research output: Contribution to journalShort survey

Clustered Regularly Interspaced Short Palindromic Repeats
Hearing