Vilmos Adleff – Research Output — Johns Hopkins University

2017

Direct detection of early-stage cancers using circulating tumor DNA

Phallen, J., Sausen, M., Adleff, V., Leal, A., Hruban, C., White, J., Anagnostou, V., Fiksel, J., Cristiano, S., Papp, E., Speir, S., Reinert, T., Orntoft, M. B. W., Woodward, B. D., Murphy, D., Parpart-Li, S., Riley, D., Nesselbush, M., Sengamalay, N., Georgiadis, A. & 17 othersLi, Q. K., Madsen, M. R., Mortensen, F. V., Huiskens, J., Punt, C., Van Grieken, N., Fijneman, R., Meijer, G., Husain, H., Scharpf, R. B., Diaz, L. A., Jones, S., Angiuoli, S., Ørntoft, T., Nielsen, H. J., Andersen, C. L. & Velculescu, V. E., Aug 16 2017, In : Science Translational Medicine. 9, 403, eaan2415.

Research output: Contribution to journal › Article

Early Detection of Cancer

DNA

Neoplasms

High-Throughput Nucleotide Sequencing

Mutation

Establishment of patient-derived tumor xenograft models of epithelial ovarian cancer for preclinical evaluation of novel therapeutics

Liu, J. F., Palakurthi, S., Zeng, Q., Zhou, S., Ivanova, E., Huang, W., Zervantonakis, I. K., Selfors, L. M., Shen, Y., Pritchard, C. C., Zheng, M., Adleff, V., Papp, E., Piao, H., Novak, M., Fotheringham, S., Wulf, G. M., English, J., Kirschmeier, P. T., Velculescu, V. E. & 6 othersPaweletz, C., Mills, G. B., Livingston, D. M., Brugge, J. S., Matulonis, U. A. & Drapkin, R., Mar 1 2017, In : Clinical Cancer Research. 23, 5, p. 1263-1273 11 p.

Research output: Contribution to journal › Article

Heterografts

Neoplasms

Therapeutics

Tumor Burden

Ovarian Neoplasms

Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer

Anagnostou, V., Smith, K., Forde, P., Niknafs, N., Bhattacharya, R., White, J., Zhang, T., Adleff, V., Phallen, J., Wali, N., Hruban, C., Guthrie, V. B., Rodgers, K., Naidoo, J., Kang, H., Sharfman, W., Georgiades, C. S., Verde, F., Illei, P. B., Li, Q. K. & 9 othersGabrielson, E., Brock, M. V., Zahnow, C., Baylin, S. B., Scharpf, R. B., Brahmer, J., Karchin, R., Pardoll, A. M. & Velculescu, V. E., Mar 1 2017, In : Cancer Discovery. 7, 3, p. 264-276 13 p.

Research output: Contribution to journal › Article

Non-Small Cell Lung Carcinoma

Neoplasms

T-Lymphocytes

Mutation

T-Cell Antigen Receptor

High grade serous ovarian carcinomas originate in the fallopian tube

Labidi-Galy, S. I., Papp, E., Hallberg, D., Niknafs, N., Adleff, V., Noe, M., Bhattacharya, R., Novak, M., Jones, S., Phallen, J., Hruban, C. A., Hirsch, M. S., Lin, D. I., Schwartz, L., Maire, C. L., Tille, J. C., Bowden, M., Ayhan, A., Wood, L. D., Scharpf, R. B. & 6 othersKurman, R. J., Wang, T-L., Shih, I. M., Karchin, R., Drapkin, R. & Velculescu, V. E., Dec 1 2017, In : Nature Communications. 8, 1, 1093.

Research output: Contribution to journal › Article

Fallopian Tubes

Carcinoma in Situ

Tumors

grade

cancer

The effect of preservative and temperature on the analysis of circulating tumor DNA

Parpart-Li, S., Bartlett, B., Popoli, M., Adleff, V., Tucker, L., Steinberg, R., Georgiadis, A., Phallen, J., Brahmer, J., Azad, N., Browner, I., Laheru, D., Velculescu, V. E., Sausen, M. & Diaz, L. A., May 15 2017, In : Clinical Cancer Research. 23, 10, p. 2471-2477 7 p.

Research output: Contribution to journal › Article

Temperature

DNA

Neoplasms

Serum

Edetic Acid

2015

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

Sausen, M., Phallen, J., Adleff, V., Jones, S., Leary, R. J., Barrett, M. T., Anagnostou, V., Parpart-Li, S., Murphy, D., Li, Q. K., Hruban, C. A., Scharpf, R. B., White, J. R., O'Dwyer, P. J., Allen, P. J., Eshleman, J., Thompson, C. B., Klimstra, D. S., Linehan, D. C., Maitra, A. & 6 othersHruban, R. H., Diaz, L. A., Von Hoff, D. D., Johansen, J. S., Drebin, J. A. & Velculescu, V. E., Jul 7 2015, In : Nature Communications. 6, 7686.

Research output: Contribution to journal › Article

Pancreatic Neoplasms

Tumors

tumors

cancer

Neoplasms

The genomic landscape of response to EGFR blockade in colorectal cancer

Bertotti, A., Papp, E., Jones, S., Adleff, V., Anagnostou, V., Lupo, B., Sausen, M., Phallen, J., Hruban, C. A., Tokheim, C., Niknafs, N., Nesselbush, M., Lytle, K., Sassi, F., Cottino, F., Migliardi, G., Zanella, E. R., Ribero, D., Russolillo, N., Mellano, A. & 15 othersMuratore, A., Paraluppi, G., Salizzoni, M., Marsoni, S., Kragh, M., Lantto, J., Cassingena, A., Li, Q. K., Karchin, R., Scharpf, R. B., Sartore-Bianchi, A., Siena, S., Diaz, L. A., Trusolino, L. & Velculescu, V. E., Oct 8 2015, In : Nature. 526, 7572, p. 263-267 5 p.

Research output: Contribution to journal › Article

Epidermal Growth Factor Receptor

Colorectal Neoplasms

Neoplasms

Therapeutics

Transplants