Vilmos Adleff

Research Associate

20152017
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Research Output 2015 2017

2017

Direct detection of early-stage cancers using circulating tumor DNA

Phallen, J. , Sausen, M. , Adleff, V. , Leal, A. , Hruban, C. , White, J. , Anagnostou, V. , Fiksel, J. , Cristiano, S. , Papp, E. , Speir, S. , Reinert, T. , Orntoft, M. B. W. , Woodward, B. D. , Murphy, D. , Parpart-Li, S. , Riley, D. , Nesselbush, M. , Sengamalay, N. , Georgiadis, A. & 17 others Li, Q. K., Madsen, M. R., Mortensen, F. V., Huiskens, J., Punt, C., Van Grieken, N., Fijneman, R., Meijer, G., Husain, H., Scharpf, R. B., Diaz, L. A., Jones, S., Angiuoli, S., Ørntoft, T., Nielsen, H. J., Andersen, C. L. & Velculescu, V. E., Aug 16 2017, In : Science Translational Medicine. 9, 403, eaan2415

Research output: Contribution to journalArticle

Early Detection of Cancer
DNA
Neoplasms
High-Throughput Nucleotide Sequencing
Mutation

Establishment of patient-derived tumor xenograft models of epithelial ovarian cancer for preclinical evaluation of novel therapeutics

Liu, J. F. , Palakurthi, S. , Zeng, Q. , Zhou, S. , Ivanova, E. , Huang, W. , Zervantonakis, I. K. , Selfors, L. M. , Shen, Y. , Pritchard, C. C. , Zheng, M. , Adleff, V. , Papp, E. , Piao, H. , Novak, M. , Fotheringham, S. , Wulf, G. M. , English, J. , Kirschmeier, P. T. , Velculescu, V. E. & 6 others Paweletz, C., Mills, G. B., Livingston, D. M., Brugge, J. S., Matulonis, U. A. & Drapkin, R., Mar 1 2017, In : Clinical Cancer Research. 23, 5, p. 1263-1273 11 p.

Research output: Contribution to journalArticle

Heterografts
Neoplasms
Therapeutics
Tumor Burden
Ovarian Neoplasms

Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer

Anagnostou, V. , Smith, K. N. , Forde, P. M. , Niknafs, N. , Bhattacharya, R. , White, J. , Zhang, T. , Adleff, V. , Phallen, J. , Wali, N. , Hruban, C. , Guthrie, V. B. , Rodgers, K. , Naidoo, J. , Kang, H. , Sharfman, W. , Georgiades, C. , Verde, F. , Illei, P. , Li, Q. K. & 9 others Gabrielson, E., Brock, M. V., Zahnow, C. A., Baylin, S. B., Scharpf, R. B., Brahmer, J. R., Karchin, R., Pardoll, D. M. & Velculescu, V. E., Mar 1 2017, In : Cancer Discovery. 7, 3, p. 264-276 13 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Neoplasms
T-Lymphocytes
Mutation
T-Cell Antigen Receptor

High grade serous ovarian carcinomas originate in the fallopian tube

Labidi-Galy, S. I. , Papp, E. , Hallberg, D. , Niknafs, N. , Adleff, V. , Noe, M. , Bhattacharya, R. , Novak, M. , Jones, S. , Phallen, J. , Hruban, C. A. , Hirsch, M. S. , Lin, D. I. , Schwartz, L. , Maire, C. L. , Tille, J. C. , Bowden, M. , Ayhan, A. , Wood, L. D. , Scharpf, R. B. & 6 others Kurman, R., Wang, T. L., Shih, I. M., Karchin, R., Drapkin, R. & Velculescu, V. E., Dec 1 2017, In : Nature Communications. 8, 1, 1093

Research output: Contribution to journalArticle

cancer
etiology
lesion
tumor
laser

The effect of preservative and temperature on the analysis of circulating tumor DNA

Parpart-Li, S., Bartlett, B., Popoli, M., Adleff, V., Tucker, L., Steinberg, R., Georgiadis, A., Phallen, J., Brahmer, J., Azad, N., Browner, I., Laheru, D., Velculescu, V. E., Sausen, M. & Diaz, L. A., May 15 2017, In : Clinical Cancer Research. 23, 10, p. 2471-2477 7 p.

Research output: Contribution to journalArticle

Temperature
DNA
Neoplasms
Edetic Acid
Serum
2015

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

Sausen, M. , Phallen, J. , Adleff, V. , Jones, S. , Leary, R. J. , Barrett, M. T. , Anagnostou, V. , Parpart-Li, S. , Murphy, D. , Li, Q. K. , Hruban, C. A. , Scharpf, R. , White, J. R. , O'Dwyer, P. J. , Allen, P. J. , Eshleman, J. R. , Thompson, C. B. , Klimstra, D. S. , Linehan, D. C. , Maitra, A. & 6 others Hruban, R. H., Diaz, L. A., Von Hoff, D. D., Johansen, J. S., Drebin, J. A. & Velculescu, V. E., Jul 7 2015, In : Nature Communications. 6, 7686

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Tumors
tumors
cancer
Neoplasms

The genomic landscape of response to EGFR blockade in colorectal cancer

Bertotti, A. , Papp, E. , Jones, S. , Adleff, V. , Anagnostou, V. , Lupo, B. , Sausen, M. , Phallen, J. , Hruban, C. A. , Tokheim, C. , Niknafs, N. , Nesselbush, M. , Lytle, K. , Sassi, F. , Cottino, F. , Migliardi, G. , Zanella, E. R. , Ribero, D. , Russolillo, N. , Mellano, A. & 15 others Muratore, A., Paraluppi, G., Salizzoni, M., Marsoni, S., Kragh, M., Lantto, J., Cassingena, A., Li, Q. K., Karchin, R., Scharpf, R., Sartore-Bianchi, A., Siena, S., Diaz, L. A., Trusolino, L. & Velculescu, V. E., Oct 8 2015, In : Nature. 526, 7572, p. 263-267 5 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Colorectal Neoplasms
Neoplasms
Therapeutics
Transplants