Victor E Velculescu

Professor

1993 …2019
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  • 3 Similar Profiles
Neoplasms Medicine & Life Sciences
Mutation Medicine & Life Sciences
Colorectal Neoplasms Medicine & Life Sciences
Genes Medicine & Life Sciences
Genome Medicine & Life Sciences
DNA Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences

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Research Output 1993 2019

Addressing the dichotomy between individual and societal approaches to personalised medicine in oncology

the IBCD-Faculty, Jun 1 2019, In : European Journal of Cancer. 114, p. 128-136 9 p.

Research output: Contribution to journalArticle

Precision Medicine
Neoplasms
Delivery of Health Care
Tumor Biomarkers
Industry

Combined MEK and Bcl-2/X L inhibition is effective in high-grade serous ovarian cancer patient–derived xenograft models and BIM levels are predictive of responsiveness

Iavarone, C., Zervantonakis, I. K., Selfors, L. M., Palakurthi, S., Liu, J. F., Drapkin, R., Matulonis, U. A., Hallberg, D., Velculescu, V. E., Leverson, J. D., Sampath, D., Mills, G. B. & Brugge, J. S., Mar 1 2019, In : Molecular cancer therapeutics. 18, 3, p. 642-655 14 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Heterografts
Ovarian Neoplasms
MAP Kinase Signaling System
Drug Combinations

Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1 (Journal for Immuno Therapy of Cancer (2019) 7 (40) DOI: 10.1186/s40425-018-0492-x)

Smith, K., Llosa, N., Cottrell, T. R., Siegel, N., Fan, H., Suri, P., Chan, H. Y., Guo, H., Oke, T., Awan, A. H., Verde, F., Danilova, L. V., Anagnostou, V., Tam, A. J., Luber, B. S., Bartlett, B. R., Aulakh, L. K., Sidhom, J. W., Zhu, Q., Sears, C. L. & 21 others, Cope, L., Sharfman, W., Thompson, E., Riemer, J., Marrone, K., Naidoo, J., Velculescu, V. E., Forde, P., Vogelstein, B., Kinzler, K. W., Papadopoulos, N., Durham, J. N., Wang, H., Le, D., Justesen, S., Taube, J. M., Diaz, L. A., Brahmer, J., Pardoll, A. M., Anders, R. A. & Housseau, F., Mar 6 2019, In : Journal for immunotherapy of cancer. 7, 1, 7.

Research output: Contribution to journalComment/debate

Consultants
Oncogenes
T-Lymphocytes
Conflict of Interest
Organized Financing

Dynamics of tumor and immune responses during immune checkpoint blockade in non–small cell lung cancer

Anagnostou, V., Forde, P., White, J. R., Niknafs, N., Hruban, C., Naidoo, J., Marrone, K., Ashok Sivakumar, I. K., Bruhm, D. C., Rosner, S., Phallen, J., Leal, A., Adleff, V., Smith, K., Cottrell, T. R., Rhymee, L., Palsgrove, D. N., Hann, C., Levy, B., Feliciano, J. & 16 others, Georgiades, C. S., Verde, F., Illei, P. B., Li, Q. K., Gabrielson, E., Brock, M. V., Isbell, J. M., Sauter, J. L., Taube, J. M., Scharpf, R. B., Karchin, R., Pardoll, A. M., Chaft, J. E., Hellmann, M. D., Brahmer, J. & Velculescu, V. E., Jan 1 2019, In : Cancer Research. 79, 6, p. 1214-1225 12 p.

Research output: Contribution to journalArticle

Open Access
Non-Small Cell Lung Carcinoma
DNA
Neoplasms
Therapeutics
Confidence Intervals

Early noninvasive detection of response to targeted therapy in non–small cell lung cancer

Phallen, J., Leal, A., Woodward, B. D., Forde, P., Naidoo, J., Marrone, K., Brahmer, J., Fiksel, J., Medina, J. E., Cristiano, S., Palsgrove, D. N., Gocke, C., Bruhm, D. C., Keshavarzian, P., Adleff, V., Weihe, E., Anagnostou, V., Scharpf, R. B., Velculescu, V. E. & Husain, H., Jan 1 2019, In : Cancer Research. 79, 6, p. 1204-1213 10 p.

Research output: Contribution to journalArticle

Open Access
Non-Small Cell Lung Carcinoma
DNA
Neoplasms
Circulating Neoplastic Cells
Therapeutics