Vasiliki Machairaki

Assistant Professor

20012018
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Research Output 2001 2018

Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system

Wu, M., Liu, S., Gao, Y., Bai, H., Machairaki, V., Li, G., Chen, T. & Cheng, L. May 1 2018 In : Stem Cell Research. 29, p. 6-14 9 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Gene Knockout Techniques
Guide RNA
Gene Order
Transgenes

A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease

Cai, L., Bai, H., Mahairaki, V., Gao, Y., He, C., Wen, Y., Jin, Y. C., Wang, Y., Pan, R. L., Qasba, A., Ye, Z. & Cheng, L. Jan 1 2017 (Accepted/In press) In : Stem Cells Translational Medicine.

Research output: Contribution to journalArticle

beta-Thalassemia
Sickle Cell Anemia
Cell- and Tissue-Based Therapy
Genetic Therapy
Stem Cells

Isolation and characterization of extracellular vesicles in stem cell-related studies

Zhao, Z., Muth, D. C., Mahairaki, V., Cheng, L. & Witwer, K. W. 2017 Neuromethods. Humana Press Inc., Vol. 126, p. 205-223 19 p. (Neuromethods; vol. 126)

Research output: Chapter in Book/Report/Conference proceedingChapter

Stem cells
Stem Cells
Centrifugation
Ultracentrifugation
Purification

Transplantation of human oligodendrocyte progenitor cells in an animal model of diffuse traumatic axonal injury: Survival and differentiation

Xu, L., Ryu, J., Hiel, H., Menon, A., Aggarwal, A., Rha, E., Mahairaki, V., Cummings, B. J. & Koliatsos, V. E. May 14 2015 In : Stem Cell Research and Therapy. 6, 1, 93

Research output: Contribution to journalArticle

Diffuse Axonal Injury
Transplants
Oligodendroglia
Stem cells
Rats

Induced pluripotent stem cells from familial alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties

Mahairaki, V., Ryu, J., Peters, A., Chang, Q., Li, T., Park, T. S., Burridge, P. W., Talbot, C. C., Asnaghi, L., Martin, L. J., Zambidis, E. T. & Koliatsos, V. E. Dec 15 2014 In : Stem Cells and Development. 23, 24, p. 2996-3010 15 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Alzheimer Disease
Presenilin-1
Neurons
Mutation