Vasiliki Machairaki

Assistant Professor

20012018
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Research Output 2001 2018

Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system

Wu, M., Liu, S., Gao, Y., Bai, H., Machairaki, V., Li, G., Chen, T. & Cheng, L., May 1 2018, In : Stem Cell Research. 29, p. 6-14 9 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Gene Knockout Techniques
Guide RNA
Gene Order
Transgenes

A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease

Cai, L., Bai, H., Machairaki, V., Gao, Y., He, C., Wen, Y., Jin, Y. C., Wang, Y., Pan, R. L., Qasba, A., Ye, Z. & Cheng, L., Jan 1 2017, (Accepted/In press) In : Stem cells translational medicine.

Research output: Contribution to journalArticle

beta-Thalassemia
Sickle Cell Anemia
Cell- and Tissue-Based Therapy
Genetic Therapy
Stem Cells

Isolation and characterization of extracellular vesicles in stem cell-related studies

Zhao, Z., Muth, D. C., Machairaki, V., Cheng, L. & Witwer, K. W., 2017, Neuromethods. Humana Press Inc., Vol. 126. p. 205-223 19 p. (Neuromethods; vol. 126).

Research output: Chapter in Book/Report/Conference proceedingChapter

Stem cells
Stem Cells
Centrifugation
Ultracentrifugation
Purification

Extracellular vesicle-associated aβ mediates trans-neuronal bioenergetic and ca2+-handling deficits in alzheimer’s disease models

Eitan, E., Hutchison, E. R., Marosi, K., Comotto, J., Mustapic, M., Nigam, S. M., Suire, C., Maharana, C., Jicha, G. A., Liu, D., Machairaki, V., Witwer, K. W., Kapogiannis, D. & Mattson, M. P., Jan 1 2016, In : npj Aging and Mechanisms of Disease. 2, 1, 16019.

Research output: Contribution to journalArticle

Energy Metabolism
Alzheimer Disease
Amyloid beta-Peptides
Presenilin-1
Exosomes

Transplantation of human oligodendrocyte progenitor cells in an animal model of diffuse traumatic axonal injury: Survival and differentiation

Xu, L., Ryu, J., Hiel, H., Menon, A., Aggarwal, A., Rha, E., Machairaki, V., Cummings, B. J. & Koliatsos, V. E., May 14 2015, In : Stem Cell Research and Therapy. 6, 1, 93.

Research output: Contribution to journalArticle

Diffuse Axonal Injury
Transplants
Oligodendroglia
Stem cells
Rats