Valsamo Anagnostou

Assistant Professor

20042018
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Mutation Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Proteins Medicine & Life Sciences
Cold Ischemia Medicine & Life Sciences

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Research Output 2004 2018

A machine learning approach for somatic mutation discovery

Wood, D. E., White, J. R., Georgiadis, A., Van Emburgh, B., Parpart-Li, S., Mitchell, J., Anagnostou, V., Niknafs, N., Karchin, R., Papp, E., McCord, C., LoVerso, P., Riley, D., Diaz, L. A., Jones, S., Sausen, M., Velculescu, V. E. & Angiuoli, S. V., Sep 5 2018, In : Science translational medicine. 10, 457, aar7939

Research output: Contribution to journalArticle

Mutation
Neoplasms
Atlases
Genome
Exome

Neoadjuvant PD-1 blockade in resectable lung cancer

Forde, P. M. , Chaft, J. E. , Smith, K. N. , Anagnostou, V. , Cottrell, T. R. , Hellmann, M. D. , Zahurak, M. , Broderick, S. , Yang, S. C. , Jones, D. R. , Battafarano, R. J. , Velez, M. J. , Rekhtman, N. , Olah, Z. , Verde, F. , Naidoo, J. , Marrone, K. A. , Guo, H. , Sidhom, J. W. , Zhang, J. & 15 others Caushi, J. X., Chan, H. Y., Scharpf, R. B., White, J., Gabrielson, E., Wang, H., Rosner, G. L., Rusch, V., Wolchok, J. D., Merghoub, T., Taube, J. M., Velculescu, V. E., Topalian, S. L., Brahmer, J. R. & Pardoll, D. M., May 24 2018, In : New England Journal of Medicine. 378, 21, p. 1976-1986 11 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Clone Cells
Neoplasms
Non-Small Cell Lung Carcinoma
T-Lymphocytes
Immunity
T-Lymphocytes
Mutation
Antigens
Cytokines

Direct detection of early-stage cancers using circulating tumor DNA

Phallen, J. , Sausen, M. , Adleff, V. , Leal, A. , Hruban, C. , White, J. , Anagnostou, V. , Fiksel, J. , Cristiano, S. , Papp, E. , Speir, S. , Reinert, T. , Orntoft, M. B. W. , Woodward, B. D. , Murphy, D. , Parpart-Li, S. , Riley, D. , Nesselbush, M. , Sengamalay, N. , Georgiadis, A. & 17 others Li, Q. K., Madsen, M. R., Mortensen, F. V., Huiskens, J., Punt, C., Van Grieken, N., Fijneman, R., Meijer, G., Husain, H., Scharpf, R. B., Diaz, L. A., Jones, S., Angiuoli, S., Ørntoft, T., Nielsen, H. J., Andersen, C. L. & Velculescu, V. E., Aug 16 2017, In : Science Translational Medicine. 9, 403, eaan2415

Research output: Contribution to journalArticle

Early Detection of Cancer
DNA
Neoplasms
High-Throughput Nucleotide Sequencing
Mutation

Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

Topper, M. J., Vaz, M., Chiappinelli, K. B., DeStefano Shields, C. E., Niknafs, N., Yen, R. W. C., Wenzel, A., Hicks, J., Ballew, M., Stone, M., Tran, P. T., Zahnow, C. A., Hellmann, M. D., Anagnostou, V., Strissel, P. L., Strick, R., Velculescu, V. E. & Baylin, S. B., Nov 30 2017, In : Cell. 171, 6, p. 1284-1300.e21

Research output: Contribution to journalArticle

Immune Evasion
T-cells
Epigenomics
Non-Small Cell Lung Carcinoma
Lung Neoplasms