Valsamo Anagnostou

Assistant Professor

20042018
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Proteins Medicine & Life Sciences
Cold Ischemia Medicine & Life Sciences
Antibodies Medicine & Life Sciences

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Research Output 2004 2018

Neoadjuvant PD-1 blockade in resectable lung cancer

Forde, P. M. , Chaft, J. E. , Smith, K. N. , Anagnostou, V. , Cottrell, T. R. , Hellmann, M. D. , Zahurak, M. , Broderick, S. , Yang, S. C. , Jones, D. R. , Battafarano, R. J. , Velez, M. J. , Rekhtman, N. , Olah, Z. , Verde, F. , Naidoo, J. , Marrone, K. A. , Guo, H. , Sidhom, J. W. , Zhang, J. & 15 others Caushi, J. X., Chan, H. Y., Scharpf, R. B., White, J., Gabrielson, E., Wang, H., Rosner, G. L., Rusch, V., Wolchok, J. D., Merghoub, T., Taube, J. M., Velculescu, V. E., Topalian, S. L., Brahmer, J. R. & Pardoll, D. M. May 24 2018 In : New England Journal of Medicine. 378, 21, p. 1976-1986 11 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Clone Cells
Neoplasms
Non-Small Cell Lung Carcinoma
T-Lymphocytes

Direct detection of early-stage cancers using circulating tumor DNA

Phallen, J. , Sausen, M. , Adleff, V. , Leal, A. , Hruban, C. , White, J. , Anagnostou, V. , Fiksel, J. , Cristiano, S. , Papp, E. , Speir, S. , Reinert, T. , Orntoft, M. B. W. , Woodward, B. D. , Murphy, D. , Parpart-Li, S. , Riley, D. , Nesselbush, M. , Sengamalay, N. , Georgiadis, A. & 17 others Li, Q. K., Madsen, M. R., Mortensen, F. V., Huiskens, J., Punt, C., Van Grieken, N., Fijneman, R., Meijer, G., Husain, H., Scharpf, R. B., Diaz, L. A., Jones, S., Angiuoli, S., Ørntoft, T., Nielsen, H. J., Andersen, C. L. & Velculescu, V. E. Aug 16 2017 In : Science translational medicine. 9, 403, eaan2415

Research output: Contribution to journalArticle

Early Detection of Cancer
DNA
Neoplasms
High-Throughput Nucleotide Sequencing
Mutation

Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

Topper, M. J., Vaz, M., Chiappinelli, K. B., DeStefano Shields, C. E., Niknafs, N., Yen, R. W. C., Wenzel, A., Hicks, J., Ballew, M., Stone, M., Tran, P. T., Zahnow, C. A., Hellmann, M. D., Anagnostou, V., Strissel, P. L., Strick, R., Velculescu, V. E. & Baylin, S. B. Nov 30 2017 In : Cell. 171, 6, p. 1284-1300.e21

Research output: Contribution to journalArticle

Immune Evasion
T-cells
Epigenomics
Non-Small Cell Lung Carcinoma
Lung Neoplasms

Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer

Anagnostou, V. , Smith, K. N. , Forde, P. M. , Niknafs, N. , Bhattacharya, R. , White, J. , Zhang, T. , Adleff, V. , Phallen, J. , Wali, N. , Hruban, C. , Guthrie, V. B. , Rodgers, K. , Naidoo, J. , Kang, H. , Sharfman, W. , Georgiades, C. , Verde, F. , Illei, P. , Li, Q. K. & 9 others Gabrielson, E., Brock, M. V., Zahnow, C. A., Baylin, S. B., Scharpf, R. B., Brahmer, J. R., Karchin, R., Pardoll, D. M. & Velculescu, V. E. Mar 1 2017 In : Cancer Discovery. 7, 3, p. 264-276 13 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Neoplasms
T-Lymphocytes
Mutation
T-Cell Antigen Receptor

Immuno-oncology trial endpoints: Capturing clinically meaningful activity

Anagnostou, V., Yarchoan, M., Hansen, A. R., Wang, H., Verde, F., Sharon, E., Collyar, D., Chow, L. Q. M. & Forde, P. M. Sep 1 2017 In : Clinical Cancer Research. 23, 17, p. 4959-4969 11 p.

Research output: Contribution to journalArticle

Clinical Trials
Biomarkers
Survival Rate
Drug Therapy
Therapeutics