Valina Dawson

Professor

1988 …2020

Research output per year

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Research Output

2020
Open Access

PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency

Pirooznia, S. K., Yuan, C., Khan, M. R., Karuppagounder, S. S., Wang, L., Xiong, Y., Kang, S. U., Lee, Y., Dawson, V. L. & Dawson, T. M., Mar 5 2020, In : Molecular neurodegeneration. 15, 1, 17.

Research output: Contribution to journalArticle

Open Access
Open Access

Poly (ADP-ribose) (PAR)-dependent cell death in neurodegenerative diseases

Park, H., Kam, T. I., Dawson, T. M. & Dawson, V. L., 2020, International Review of Cell and Molecular Biology. Spetz, J. K. E. & Galluzzi, L. (eds.). Elsevier Inc., p. 1-29 29 p. (International Review of Cell and Molecular Biology; vol. 353).

Research output: Chapter in Book/Report/Conference proceedingChapter

Quantitative mass spectrometric analysis of the mouse cerebral cortex after ischemic stroke

Agarwal, A., Park, S., Ha, S., Kwon, J. S., Khan, M. R., Kang, B. G., Dawson, T. M., Dawson, V. L., Andrabi, S. A. & Kang, S. U., Apr 2020, In : PloS one. 15, 4, e0231978.

Research output: Contribution to journalArticle

Open Access
2019

Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia

Panicker, N., Sarkar, S., Harischandra, D. S., Neal, M., Kam, T. I., Jin, H., Saminathan, H., Langley, M., Charli, A., Samidurai, M., Rokad, D., Ghaisas, S., Pletnikova, O., Dawson, V. L., Dawson, T. M., Anantharam, V., Kanthasamy, A. G. & Kanthasamy, A., Jun 1 2019, In : Journal of Experimental Medicine. 216, 6, p. 1411-1430 20 p.

Research output: Contribution to journalArticle

Open Access

Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis

Jin, J., Smith, M. D., Kersbergen, C. J., Kam, T. I., Viswanathan, M., Martin, K., Dawson, T. M., Dawson, V. L., Zack, D. J., Whartenby, K. & Calabresi, P. A., Jul 31 2019, In : Acta Neuropathologica Communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease

Brahmachari, S., Lee, S., Kim, S., Yuan, C., Karuppagounder, S. S., Ge, P., Shi, R., Kim, E. J., Liu, A., Kim, D., Quintin, S., Jiang, H., Kumar, M., Yun, S. P., Kam, T. I., Mao, X., Lee, Y., Swing, D. A., Tessarollo, L., Ko, H. S. & 2 others, Dawson, V. L. & Dawson, T. M., Aug 1 2019, In : Brain. 142, 8, p. 2380-2401 22 p.

Research output: Contribution to journalArticle

Promising disease-modifying therapies for Parkinson’s disease

Dawson, V. L. & Dawson, T. M., Nov 27 2019, In : Science translational medicine. 11, 520, eaba1659.

Research output: Contribution to journalArticle

Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons

Xue, Y., Zhan, X., Sun, S., Karuppagounder, S. S., Xia, S., Dawson, V. L., Dawson, T. M., Laterra, J., Zhang, J. & Ying, M., Feb 1 2019, In : Stem Cells Translational Medicine. 8, 2, p. 112-123 12 p.

Research output: Contribution to journalArticle

The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration

Hinkle, J. T., Dawson, V. & Dawson, T. M., Jul 1 2019, In : Movement Disorders. 34, 7, p. 959-969 11 p.

Research output: Contribution to journalArticle

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease

Kim, S., Kwon, S. H., Kam, T. I., Panicker, N., Karuppagounder, S. S., Lee, S., Lee, J. H., Kim, W. R., Kook, M., Foss, C. A., Shen, C., Lee, H., Kulkarni, S., Pasricha, P. J., Lee, G., Pomper, M. G., Dawson, V. L., Dawson, T. M. & Ko, H. S., Aug 21 2019, In : Neuron. 103, 4, p. 627-641.e7

Research output: Contribution to journalArticle

2018

A homozygous ATAD1 mutation impairs postsynaptic AMPA receptor trafficking and causes a lethal encephalopathy

Piard, J., Umanah, G., Harms, F. L., Abalde-Atristain, L., Amram, D., Chang, M., Chen, R., Alawi, M., Salpietro, V., Rees, M. I., Chung, S. K., Houlden, H., Verloes, A., Dawson, T. M., Dawson, V., Van Maldergem, L. & Kutsche, K., Mar 1 2018, In : Brain. 141, 3, p. 651-661 11 p.

Research output: Contribution to journalArticle

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease

Yun, S. P., Kam, T. I., Panicker, N., Kim, S., Oh, Y., Park, J. S., Kwon, S. H., Park, Y. J., Karuppagounder, S. S., Park, H., Kim, S., Oh, N., Kim, N. A., Lee, S., Brahmachari, S., Mao, X., Lee, J. H., Kumar, M., An, D., Kang, S. U. & 13 others, Lee, Y., Lee, K. C., Na, D. H., Kim, D., Lee, S. H., Roschke, V. V., Liddelow, S. A., Mari, Z., Barres, B. A., Dawson, V. L., Lee, S., Dawson, T. M. & Ko, H. S., Jul 1 2018, In : Nature medicine. 24, 7, p. 931-938 8 p.

Research output: Contribution to journalArticle

DISC1 regulates lactate metabolism in astrocytes: Implications for psychiatric disorders

Jouroukhin, Y., Kageyama, Y., Misheneva, V., Shevelkin, A., Andrabi, S., Prandovszky, E., Yolken, R. H., Dawson, V., Dawson, T. M., Aja, S. M., Sesaki, H. & Pletnikov, M., Dec 1 2018, In : Translational Psychiatry. 8, 1, 76.

Research output: Contribution to journalArticle

Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration

Jeong, G. R., Jang, E. H., Bae, J. R., Jun, S., Kang, H. C., Park, C. H., Shin, J. H., Yamamoto, Y., Tanaka-Yamamoto, K., Dawson, V., Dawson, T. M., Hur, E. M. & Lee, B. D., Feb 13 2018, In : Molecular Neurodegeneration. 13, 1, 8.

Research output: Contribution to journalArticle

Excitotoxic programmed cell death involves caspase-independent mechanisms

Dawson, T. M. & Dawson, V., Jan 1 2018, Acute Neuronal Injury: The Role of Excitotoxic Programmed Cell Death Mechanisms: Second Edition. Springer International Publishing, p. 3-17 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers

Kim, S., Yun, S. P., Lee, S., Umanah, G., Bandaru, V. V. R., Yin, X., Rhee, P., Karuppagounder, S., Kwon, S. H., Lee, H., Mao, X., Kim, D., Pandey, A., Lee, G., Dawson, V., Dawson, T. M. & Ko, H. S., Jan 23 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. 798-803 6 p.

Research output: Contribution to journalArticle

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases

Connolly, N. M. C., Theurey, P., Adam-Vizi, V., Bazan, N. G., Bernardi, P., Bolaños, J. P., Culmsee, C., Dawson, V. L., Deshmukh, M., Duchen, M. R., Düssmann, H., Fiskum, G., Galindo, M. F., Hardingham, G. E., Hardwick, J. M., Jekabsons, M. B., Jonas, E. A., Jordán, J., Lipton, S. A., Manfredi, G. & 26 others, Mattson, M. P., McLaughlin, B. A., Methner, A., Murphy, A. N., Murphy, M. P., Nicholls, D. G., Polster, B. M., Pozzan, T., Rizzuto, R., Satrústegui, J., Slack, R. S., Swanson, R. A., Swerdlow, R. H., Will, Y., Ying, Z., Joselin, A., Gioran, A., Moreira Pinho, C., Watters, O., Salvucci, M., Llorente-Folch, I., Park, D. S., Bano, D., Ankarcrona, M., Pizzo, P. & Prehn, J. H. M., Mar 1 2018, In : Cell death and differentiation. 25, 3, p. 542-572 31 p.

Research output: Contribution to journalArticle

Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 149 others, Blomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Deberardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H. U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 1 2018, In : Cell death and differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalReview article

Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases

Berger, N. A., Besson, V. C., Boulares, A. H., Bürkle, A., Chiarugi, A., Clark, R. S., Curtin, N. J., Cuzzocrea, S., Dawson, T. M., Dawson, V. L., Haskó, G., Liaudet, L., Moroni, F., Pacher, P., Radermacher, P., Salzman, A. L., Snyder, S. H., Soriano, F. G., Strosznajder, R. P., Sümegi, B. & 2 others, Swanson, R. A. & Szabo, C., Jan 1 2018, In : British Journal of Pharmacology. 175, 2, p. 192-222 31 p.

Research output: Contribution to journalReview article

Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy

Kaji, S., Maki, T., Kinoshita, H., Uemura, N., Ayaki, T., Kawamoto, Y., Furuta, T., Urushitani, M., Hasegawa, M., Kinoshita, Y., Ono, Y., Mao, X., Quach, T. H., Iwai, K., Dawson, V. L., Dawson, T. M. & Takahashi, R., Feb 13 2018, In : Stem Cell Reports. 10, 2, p. 356-365 10 p.

Research output: Contribution to journalArticle

Poly(ADP-ribose) drives pathologic a-synuclein neurodegeneration in Parkinson’s disease

Kam, T-I., Mao, X., Park, H., Chou, S. C., Karuppagounder, S., Umanah, G., Yun, S. P., Brahmachari, S., Panicker, N., Chen, R., Andrabi, S. A., Qi, C., Poirier, G. G., Pletnikova, O., Troncoso, J. C., Bekris, L. M., Leverenz, J. B., Pantelyat, A., Ko, H. S., Rosenthal, L. I. S. & 2 others, Dawson, T. M. & Dawson, V., Nov 2 2018, In : Science. 362, 6414, eaat8407.

Research output: Contribution to journalArticle

Reply: ATAD1 encephalopathy and stiff baby syndrome: A recognizable clinical presentation

Piard, J., Umanah, G., Harms, F. L., Abalde-Atristain, L., Amram, D., Chang, M., Chen, R., Alawi, M., Salpietro, V., Rees, M. I., Chung, S. K., Houlden, H., Verloes, A., Dawson, T. M., Dawson, V., Van Maldergem, L. & Kutsche, K., Jun 1 2018, In : Brain. 141, 6, p. e50

Research output: Contribution to journalLetter

Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice

Xiong, Y., Neifert, S., Karuppagounder, S. S., Liu, Q., Stankowski, J. N., Lee, B. D., Ko, H. S., Lee, Y., Grima, J. C., Mao, X., Jiang, H., Kang, S. U., Swing, D. A., Iacovitti, L., Tessarollo, L., Dawson, T. M. & Dawson, V. L., Feb 13 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 7, p. 1635-1640 6 p.

Research output: Contribution to journalArticle

The AAA + ATPase Thorase is neuroprotective against ischemic injury

Zhang, J., Yang, J., Wang, H., Sherbini, O., Keuss, M. J., Umanah, G., Pai, E. L. L., Chi, Z., Paldanius, K. M. A., He, W., Wang, H., Andrabi, S. A., Dawson, T. M. & Dawson, V., Jan 1 2018, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism

Yun, S. P., Kim, D., Kim, S., Kim, S., Karuppagounder, S., Kwon, S. H., Lee, S., Kam, T-I., Lee, S., Ham, S., Park, J. H., Dawson, V., Dawson, T. M., Lee, Y. & Ko, H. S., Jan 8 2018, In : Molecular Neurodegeneration. 13, 1, 1.

Research output: Contribution to journalArticle

2017

Activation mechanisms of the E3 ubiquitin ligase parkin

Panicker, N., Dawson, V. & Dawson, T. M., Sep 15 2017, In : Biochemical Journal. 474, 18, p. 3075-3086 12 p.

Research output: Contribution to journalReview article

Augmentation of poly(ADP-ribose) polymerase-dependent neuronal cell death by acidosis

Zhang, J., Li, X., Kwansa, H., Kim, Y. T., Yi, L., Hong, G., Andrabi, S. A., Dawson, V., Dawson, T. M., Koehler, R. C. & Yang, Z. J., Jun 1 2017, In : Journal of Cerebral Blood Flow and Metabolism. 37, 6, p. 1982-1993 12 p.

Research output: Contribution to journalArticle

C-Abl and Parkinson's Disease: Mechanisms and Therapeutic Potential

Brahmachari, S., Karuppagounder, S. S., Ge, P., Lee, S., Dawson, V. L., Dawson, T. M. & Ko, H. S., Jan 1 2017, In : Journal of Parkinson's Disease. 7, 4, p. 589-601 13 p.

Research output: Contribution to journalReview article

Cell death mechanisms of neurodegeneration

Fan, J., Dawson, T. M. & Dawson, V., 2017, Advances in Neurobiology. Springer New York LLC, Vol. 15. p. 403-425 23 p. (Advances in Neurobiology; vol. 15).

Research output: Chapter in Book/Report/Conference proceedingChapter

Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism

Puschmann, A., Fiesel, F. C., Caulfield, T. R., Hudec, R., Ando, M., Truban, D., Hou, X., Ogaki, K., Heckman, M. G., James, E. D., Swanberg, M., Jimenez-Ferrer, I., Hansson, O., Opala, G., Siuda, J., Boczarska-Jedynak, M., Friedman, A., Koziorowski, D., Rudzińska-Bar, M., Aasly, J. O. & 13 others, Lynch, T., Mellick, G. D., Mohan, M., Silburn, P. A., Sanotsky, Y., Vilariño-Güell, C., Farrer, M. J., Chen, L., Dawson, V. L., Dawson, T. M., Wszolek, Z. K., Ross, O. A. & Springer, W., Jan 1 2017, In : Brain. 140, 1, p. 98-117 20 p.

Research output: Contribution to journalArticle

Mitochondrial mechanisms of neuronal cell death: Potential the rapeutics

Dawson, T. M. & Dawson, V., Jan 6 2017, In : Annual Review of Pharmacology and Toxicology. 57, p. 437-454 18 p.

Research output: Contribution to journalReview article

Models of LRRK2-associated parkinson’s disease

Xiong, Y., Dawson, T. M. & Dawson, V. L., Apr 1 2017, Advances in Neurobiology. Springer New York LLC, p. 163-191 29 p. (Advances in Neurobiology; vol. 14).

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurotoxic reactive astrocytes are induced by activated microglia

Liddelow, S. A., Guttenplan, K. A., Clarke, L. E., Bennett, F. C., Bohlen, C. J., Schirmer, L., Bennett, M. L., Münch, A. E., Chung, W. S., Peterson, T. C., Wilton, D. K., Frouin, A., Napier, B. A., Panicker, N., Kumar, M., Buckwalter, M. S., Rowitch, D. H., Dawson, V., Dawson, T. M., Stevens, B. & 1 others, Barres, B. A., Jan 26 2017, In : Nature. 541, 7638, p. 481-487 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Signaling in Neurodegeneration and Cell Death

Dawson, T. M. & Dawson, V., 2017, (Accepted/In press) In : Advances in Pharmacology.

Research output: Contribution to journalArticle

Overexpression of Parkinson’s disease-associated mutation LRRK2 G2019S in mouse forebrain induces behavioral deficits and α-synuclein pathology

Xiong, Y., Neifert, S., Karuppagounder, S. S., Stankowski, J. N., Lee, B. D., Grima, J. C., Chen, G., Ko, H. S., Lee, Y., Swing, D., Tessarollo, L., Dawson, T. M. & Dawson, V. L., Jan 1 2017, In : eNeuro. 4, 2, e0004.

Research output: Contribution to journalArticle

PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival

Lee, Y., Stevens, D. A., Kang, S., Jiang, H., Lee, Y. I., Ko, H. S., Scarffe, L. A., Umanah, G., Kang, H., Ham, S., Kam, T-I., Allen, K., Brahmachari, S., Kim, J. W., Neifert, S., Yun, S. P., Fiesel, F. C., Springer, W., Dawson, V., Shin, J. H. & 1 others, Dawson, T. M., Jan 24 2017, In : Cell Reports. 18, 4, p. 918-932 15 p.

Research output: Contribution to journalArticle

Protein Translation in Parkinson's Disease

Kim, J. W., Abalde-Atristain, L., Jia, H., Martin, I., Dawson, T. M. & Dawson, V., Jan 6 2017, Parkinson's Disease: Molecular Mechanisms Underlying Pathology. Elsevier Inc., p. 245-279 35 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Reply: Heterozygous PINK1 p.G411S in rapid eye movement sleep behaviour disorder

Puschmann, A., Fiesel, F. C., Caulfield, T. R., Hudec, R., Ando, M., Truban, D., Hou, X., Ogaki, K., Heckman, M. G., James, E. D., Swanberg, M., Jimenez-Ferrer, I., Hansson, O., Opala, G., Siuda, J., Boczarska-Jedynak, M., Friedman, A., Koziorowski, D., Rudzińska-Bar, M., Aasly, J. O. & 13 others, Lynch, T., Mellick, G. D., Mohan, M., Silburn, P. A., Sanotsky, Y., Vilarinõ-Güell, C., Farrer, M. J., Chen, L., Dawson, V., Dawson, T. M., Wszolek, Z. K., Ross, O. A. & Springer, W., 2017, In : Brain. 140, 6, p. e33

Research output: Contribution to journalLetter

Synaptic Plasticity onto Dopamine Neurons Shapes Fear Learning

Pignatelli, M., Umanah, G., Ribeiro, S. P., Chen, R., Karuppagounder, S., Yau, H. J., Eacker, S., Dawson, V., Dawson, T. M. & Bonci, A., Jan 18 2017, In : Neuron. 93, 2, p. 425-440 16 p.

Research output: Contribution to journalArticle

T cells from patients with Parkinson's disease recognize α-synuclein peptides

Sulzer, D., Alcalay, R. N., Garretti, F., Cote, L., Kanter, E., Agin-Liebes, J., Liong, C., McMurtrey, C., Hildebrand, W. H., Mao, X., Dawson, V., Dawson, T. M., Oseroff, C., Pham, J., Sidney, J., Dillon, M. B., Carpenter, C., Weiskopf, D., Phillips, E., Mallal, S. & 4 others, Peters, B., Frazier, A., Lindestam Arlehamn, C. S. & Sette, A., Jun 29 2017, In : Nature. 546, 7660, p. 656-661 6 p.

Research output: Contribution to journalArticle

The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity

Ando, M., Fiesel, F. C., Hudec, R., Caulfield, T. R., Ogaki, K., Górka-Skoczylas, P., Koziorowski, D., Friedman, A., Chen, L., Dawson, V., Dawson, T. M., Bu, G., Ross, O. A., Wszolek, Z. K. & Springer, W., Apr 24 2017, In : Molecular Neurodegeneration. 12, 1, 32.

Research output: Contribution to journalArticle

Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel

Umanah, G. K. E., Pignatelli, M., Yin, X., Chen, R., Crawford, J., Neifert, S., Scarffe, L., Behensky, A. A., Guiberson, N., Chang, M., Ma, E., Kim, J. W., Castro, C. C., Mao, X., Chen, L., Andrabi, S. A., Pletnikov, M. V., Pulver, A. E., Avramopoulos, D., Bonci, A. & 3 others, Valle, D., Dawson, T. M. & Dawson, V. L., Dec 13 2017, In : Science translational medicine. 9, 420, aah4985.

Research output: Contribution to journalArticle

Toward the human cellular microRNAome

McCall, M. N., Kim, M. S., Adil, M., Patil, A. H., Lu, Y., Mitchell, C. J., Leal-Rojas, P., Xu, J., Kumar, M., Dawson, V. L., Dawson, T. M., Baras, A. S., Rosenberg, A. Z., Arking, D. E., Burns, K. H., Pandey, A. & Halushka, M. K., Oct 2017, In : Genome research. 27, 10, p. 1769-1781 13 p.

Research output: Contribution to journalArticle

Trumping neurodegeneration: Targeting common pathways regulated by autosomal recessive Parkinson's disease genes

Scott, L., Dawson, V. & Dawson, T. M., Jan 17 2017, (Accepted/In press) In : Experimental Neurology.

Research output: Contribution to journalArticle

Two approaches reveal a new paradigm of 'switchable or genetics-influenced allele-specific DNA methylation' with potential in human disease

Martos, S. N., Li, T., Ramos, R. B., Lou, D., Dai, H., Xu, J. C., Gao, G., Gao, Y., Wang, Q., An, C., Zhang, X., Jia, Y., Dawson, V. L., Dawson, T. M., Ji, H. & Wang, Z., Nov 14 2017, In : Cell Discovery. 3, 17038.

Research output: Contribution to journalArticle

2016

Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration

Brahmachari, S., Ge, P., Lee, S. H., Kim, D., Karuppagounder, S., Kumar, M., Mao, X., Shin, J. H., Lee, Y., Pletnikova, O., Troncoso, J. C., Dawson, V., Dawson, T. M. & Ko, H. S., Aug 1 2016, In : Journal of Clinical Investigation. 126, 8, p. 2970-2988 19 p.

Research output: Contribution to journalArticle

Adult conditional knockout of PGC-1α leads to loss of dopamine neurons

Jiang, H., Kang, S., Zhang, S., Karuppagounder, S., Xu, J., Lee, Y. K., Kang, B. G., Lee, Y., Zhang, J., Pletnikova, O., Troncoso, J. C., Pirooznia, S., Andrabi, S. A., Dawson, V. & Dawson, T. M., 2016, In : eNeuro. 3, 4, e0183-16.2016.

Research output: Contribution to journalArticle