Tzyy Choou Wu

Professor

1986 …2020

Research output per year

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Research Output

2004

Enchancement of suicidal DNA vaccine potency by delaying suicidal DNA-induced cell death

Kim, T. W., Hung, C. F., Juang, J., He, L., Hardwick, J. M. & Wu, T. C., Feb 1 2004, In : Gene Therapy. 11, 3, p. 336-342 7 p.

Research output: Contribution to journalArticle

Enhancement of DNA Vaccine Potency by Coadministration of a Tumor Antigen Gene and DNA Encoding Serine Protease Inhibitor-6

Kim, T. W., Hung, C. F., Boyd, D. A. K., He, L., Lin, C. T., Kaiserman, D., Bird, P. I. & Wu, T. C., Jan 1 2004, In : Cancer Research. 64, 1, p. 400-405 6 p.

Research output: Contribution to journalArticle

Enhancement of vaccinia vaccine potency by linkage of tumor antigen gene to gene encoding calreticulin

Hsieh, C. J., Kim, T. W., Hung, C-F., Juang, J., Moniz, M., Boyd, D. A. K., He, L., Chen, P. J., Chen, C. H. & Wu, T. C., Sep 28 2004, In : Vaccine. 22, 29-30, p. 3993-4001 9 p.

Research output: Contribution to journalArticle

Focus on endometrial and cervical cancer

Ellenson, L. H. & Wu, T. C., Jun 1 2004, In : Cancer cell. 5, 6, p. 533-538 6 p.

Research output: Contribution to journalReview article

Generation and Characterization of DNA Vaccines Targeting the Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus

Kim, T. W., Lee, J. H., Hung, C. F., Peng, S., Roden, R., Wang, M. C., Viscidi, R., Tsai, Y. C., He, L., Chen, P. J., Boyd, D. A. K. & Wu, T. C., May 2004, In : Journal of virology. 78, 9, p. 4638-4645 8 p.

Research output: Contribution to journalArticle

Human papillomavirus vaccines for the prevention and treatment of cervical cancer

Tomson, T. T., Roden, R. B. S. & Wu, T. C., Dec 1 2004, In : Current Opinion in Investigational Drugs. 5, 12, p. 1247-1261 15 p.

Research output: Contribution to journalReview article

Naked RNA vaccine controls tumors with down-regulated MHC class I expression through NK cells and perforin-dependent pathways

Cheng, W. F., Hung, C. F., Lee, C. N., Su, Y. N., Chang, M. C., He, L., Wu, T. C., Chen, C. A. & Hsieh, C. Y., Jul 1 2004, In : European Journal of Immunology. 34, 7, p. 1892-1900 9 p.

Research output: Contribution to journalArticle

Vaccination to prevent and treat cervical cancer

Roden, R. B. S., Ling, M. & Wu, T. C., Aug 2004, In : Human pathology. 35, 8, p. 971-982 12 p.

Research output: Contribution to journalArticle

Vaccination with a DNA Vaccine Encoding Herpes Simplex Virus Type 1 VP22 Linked to Antigen Generates Long-Term Antigen-Specific CD8-Positive Memory T Cells and Protective Immunity

Kim, T. W., Hung, C-F., Kim, J. W., Juang, J., Chen, P. J., He, L., Boyd, D. A. K. & Wu, T. C., 2004, In : Human Gene Therapy. 15, 2, p. 167-177 11 p.

Research output: Contribution to journalArticle

2005

A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression

Bins, A. D., Jorritsma, A., Wolkers, M. C., Hung, C. F., Wu, T. C., Schumacher, T. N. M. & Haanen, J. B. A. G., Aug 1 2005, In : Nature medicine. 11, 8, p. 899-904 6 p.

Research output: Contribution to journalArticle

Cancer immunotherapy using a DNA vaccine encoding a single-chain trimer of MHC class I linked to an HPV-16 E6 immunodominant CTL epitope

Huang, C. H., Peng, S., He, L., Tsai, Y. C., Boyd, D. A. K., Hansen, T. H., Wu, T. C. & Hung, C. F., Aug 1 2005, In : Gene Therapy. 12, 15, p. 1180-1186 7 p.

Research output: Contribution to journalArticle

Characterization of DNA vaccines encoding the domains of calreticulin for their ability to elicit tumor-specific immunity and antiangiogenesis

Cheng, W. F., Hung, C. F., Chen, C. A., Lee, C. N., Su, Y. N., Chai, C. Y., Boyd, D. A. K., Hsieh, C. Y. & Wu, T. C., May 31 2005, In : Vaccine. 23, 29, p. 3864-3874 11 p.

Research output: Contribution to journalArticle

Characterization of HPV-16 E6 DNA vaccines employing intracellular targeting and intercellular spreading strategies

Peng, S., Trimble, C., Ji, H., He, L., Tsai, Y. C., Macaes, B., Hung, C. F. & Wu, T. C., Oct 1 2005, In : Journal of biomedical science. 12, 5, p. 689-700 12 p.

Research output: Contribution to journalArticle

Control of cancers by combining antiangiogenesis and cancer immunotherapy

Moniz, M., Yeatermeyer, J. & Wu, T. C., Jul 1 2005, In : Drugs of Today. 41, 7, p. 471-494 24 p.

Research output: Contribution to journalReview article

Development of immunoglobulin G enzyme-linked immunosorbent assay for the serodiagnosis of severe acute respiratory syndrome

Shao, P. L., Hsueh, P. R., Chang, L. Y., Lu, C. Y., Kao, C. L., Chiang, Y. P., Huang, H. Y., Huang, F. Y., Lee, C. Y., Chang, L. J., Wu, T. C. & Huang, L. M., Jan 1 2005, In : Journal of biomedical science. 12, 1, p. 59-64 6 p.

Research output: Contribution to journalArticle

Immunotherapy for gynaecological malignancies

Coukos, G., Conejo-Garcia, J. R., Roden, R. B. S. & Wu, T. C., Sep 1 2005, In : Expert Opinion on Biological Therapy. 5, 9, p. 1193-1210 18 p.

Research output: Contribution to journalReview article

Modification of professional antigen-presenting cells with small interfering RNA in vivo to enhance cancer vaccine potency

Kim, T. W., Lee, J. H., He, L., Boyd, D. A. K., Hardwick, J. M., Hung, C. F. & Wu, T. C., Jan 1 2005, In : Cancer Research. 65, 1, p. 309-316 8 p.

Research output: Contribution to journalArticle

Multi-component nanorods for vaccination applications

Salem, A. K., Hung, C. F., Kim, T. W., Wu, T. C., Searson, P. C. & Leong, K. W., Apr 1 2005, In : Nanotechnology. 16, 4, p. 484-487 4 p.

Research output: Contribution to journalArticle

Spontaneous regression of high-grade cervical dysplasia: Effects of human papillomavirus type and HLA phenotype

Trimble, C. L., Piantadosi, S., Gravitt, P., Ronnett, B., Pizer, E., Elko, A., Wilgus, B., Yutzy, W., Daniel, R., Shah, K., Peng, S., Hung, C., Roden, R., Wu, T. C. & Pardoll, D., Jul 1 2005, In : Clinical Cancer Research. 11, 13, p. 4717-4723 7 p.

Research output: Contribution to journalArticle

Vaccination with dendritic cells transfected with BAK and BAX siRNA enhances antigen-specific immune responses by prolonging dendritic cell life

Peng, S., Kim, T. W., Lee, J. H., Yang, M. U., Liangmei, H. E., Hung, C. F. & Wu, T. C., May 1 2005, In : Human gene therapy. 16, 5, p. 584-593 10 p.

Research output: Contribution to journalArticle

2006

A combination of DNA vaccines targeting human papillomavirus type 16 E6 and E7 generates potent antitumor effects

Peng, S., Tomson, T. T., Trimble, C., He, L., Hung, C. F. & Wu, T. C., Feb 1 2006, In : Gene Therapy. 13, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

Characterization of HLA-A2-restricted HPV-16 E7-specific CD8+ T-cell immune responses induced by DNA vaccines in HLA-A2 transgenic mice

Peng, S., Trimble, C., He, L., Tsai, Y. C., Lin, C. T., Boyd, D. A. K., Pardoll, D., Hung, C. F. & Wu, T. C., Jan 1 2006, In : Gene Therapy. 13, 1, p. 67-77 11 p.

Research output: Contribution to journalArticle

Diffuse mesothelin expression correlates with prolonged patient survival in ovarian serous carcinoma

Yen, M. J., Hsu, C. Y., Mao, T. L., Wu, T. C., Roden, R., Wang, T. L. & Shih, L. M., Feb 1 2006, In : Clinical Cancer Research. 12, 3 I, p. 827-831 5 p.

Research output: Contribution to journalArticle

Enhancement of dendritic cell-based vaccine potency by targeting antigen to endosomal/lysosomal compartments

Kang, T. H., Lee, J. H., Bae, H. C., Noh, K. H., Kim, J. H., Song, C. K., Shin, B. C., Hung, C. F., Wu, T. C., Park, J. S. & Kim, T. W., Aug 15 2006, In : Immunology Letters. 106, 2, p. 126-134 9 p.

Research output: Contribution to journalArticle

Functional studies of lymphocytes using RNAi technology

Lin, Y. Y., Hung, C. F. & Wu, T. C., Jan 1 2006, In : Transfusion Medicine and Hemotherapy. 33, 1, p. 80-88 9 p.

Research output: Contribution to journalReview article

How will HPV vaccines affect cervical cancer?

Roden, R. & Wu, T. C., Oct 1 2006, In : Nature Reviews Cancer. 6, 10, p. 753-763 11 p.

Research output: Contribution to journalArticle

Modifying professional antigen-presenting cells to enhance DNA vaccine potency.

Hung, C. F., Yang, M. & Wu, T. C., 2006, In : Methods in Molecular Medicine. 127, p. 199-220 22 p.

Research output: Contribution to journalReview article

Prospects of RNA interference therapy for cancer

Pai, S. I., Lin, Y. Y., Macaes, B., Meneshian, A., Hung, C. F. & Wu, T. C., Mar 1 2006, In : Gene Therapy. 13, 6, p. 464-477 14 p.

Research output: Contribution to journalReview article

Sindbis virus replicon particles encoding calreticulin linked to a tumor antigen generate long-term tumor-specific immunity

Cheng, W. F., Lee, C. N., Su, Y. N., Chai, C. Y., Chang, M. C., Polo, J. M., Hung, C. F., Wu, T. C., Hsieh, C. Y. & Chen, C. A., Sep 27 2006, In : Cancer Gene Therapy. 13, 9, p. 873-885 13 p.

Research output: Contribution to journalArticle

The impact of preventive HPV vaccination.

Roden, R., Monie, A. & Wu, T. C., Oct 2006, In : Discovery Medicine. 6, 35, p. 175-181 7 p.

Research output: Contribution to journalReview article

2007

A DNA vaccine encoding a single-chain trimer of HLA-A2 linked to human mesothelin peptide generates anti-tumor effects against human mesothelin-expressing tumors

Hung, C. F., Calizo, R., Tsai, Y. C., He, L. & Wu, T. C., Jan 2 2007, In : Vaccine. 25, 1, p. 127-135 9 p.

Research output: Contribution to journalArticle

Antigen-Specific Cancer Immunotherapy: HPV-Associated Cervical Cancer as a Model System

Tsen, S. W. D., Hung, C. F. & Wu, T. C., Mar 1 2007, Cancer Vaccines and Tumor Immunity. John Wiley and Sons, p. 79-94 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cancer immunotherapy using irradiated tumor cells secreting heat shock protein 70

Chang, C. L., Tsai, Y. C., He, L., Wu, T. C. & Hung, C. F., Oct 15 2007, In : Cancer Research. 67, 20, p. 10047-10057 11 p.

Research output: Contribution to journalArticle

Control of human mesothelin-expressing tumors by DNA vaccines

Chang, C. L., Wu, T. C. & Hung, C. F., Aug 1 2007, In : Gene Therapy. 14, 16, p. 1189-1198 10 p.

Research output: Contribution to journalArticle

Control of mesothelin-expressing ovarian cancer using adoptive transfer of mesothelin peptide-specific CD8+ T cells

Hung, C. F., Tsai, Y. C., He, L. & Wu, T. C., Jun 1 2007, In : Gene Therapy. 14, 12, p. 921-929 9 p.

Research output: Contribution to journalArticle

DNA vaccines encoding Ii-PADRE generates potent PADRE-specific CD4+ t-cell immune responses and enhances vaccine potency

Hung, C. F., Tsai, Y. C., He, L. & Wu, T. C., Jun 1 2007, In : Molecular Therapy. 15, 6, p. 1211-1219 9 p.

Research output: Contribution to journalArticle

DNA vaccines for cervical cancer: From bench to bedside

Hung, C. F., Monie, A., Alvarez, R. D. & Wu, T. C., Dec 31 2007, In : Experimental and Molecular Medicine. 39, 6, p. 679-689 11 p.

Research output: Contribution to journalReview article

Open Access

Ectopic expression of vascular cell adhesion molecule-1 as a new mechanism for tumor immune evasion

Lin, K. Y., Lu, D., Hung, C. F., Peng, S., Huang, L., Jie, C., Murillo, F., Rowley, J., Tsai, Y. C., He, L., Kim, D. J., Jaffee, E., Pardoll, D. & Wu, T. C., Feb 15 2007, In : Cancer Research. 67, 4, p. 1832-1841 10 p.

Research output: Contribution to journalArticle

Enhancing dendritic cell vaccine potency by combining a BAK/BAX siRNA-mediated antiapoptotic strategy to prolong dendritic cell life with an intracellular strategy to target antigen to lysosomal compartments

Kang, T. H., Lee, J. H., Noh, K. H., Han, H. D., Shin, B. C., Choi, E. Y., Peng, S., Hung, C. F., Wu, T. C. & Kim, T. W., Apr 15 2007, In : International Journal of Cancer. 120, 8, p. 1696-1703 8 p.

Research output: Contribution to journalArticle

Enhancing DNA vaccine potency by modifying the properties of antigen-presenting cells

Tsen, S. W. D., Paik, A. H., Hung, C. F. & Wu, T. C., Apr 1 2007, In : Expert review of vaccines. 6, 2, p. 227-239 13 p.

Research output: Contribution to journalReview article

Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination

Tae, H. K., Jin, H. L., Chung, K. S., Hee, D. H., Byung, C. S., Pai, S. I., Hung, C. F., Trimble, C., Lim, J. S., Tae, W. K. & Wu, T. C., Jan 15 2007, In : Cancer Research. 67, 2, p. 802-811 10 p.

Research output: Contribution to journalArticle

Generation and characterization of an ascitogenic mesothelin-expressing tumor model

Cheng, W. F., Hung, C. F., Chai, C. Y., Chen, C. A., Lee, C. N., Su, Y. N., Tseng, W. Y. I., Hsieh, C. Y., Shih, I. M., Wang, T. L. & Wu, T. C., Jul 15 2007, In : Cancer. 110, 2, p. 420-431 12 p.

Research output: Contribution to journalArticle

Immunological research using RNA interference technology

Mao, C. P., Lin, Y. Y., Hung, C. F. & Wu, T. C., Jul 1 2007, In : Immunology. 121, 3, p. 295-307 13 p.

Research output: Contribution to journalReview article

Immunotherapeutic strategies employing RNA interference technology for the control of cancers

Mao, C. P., Hung, C. F. & Wu, T. C., Jan 1 2007, In : Journal of biomedical science. 14, 1, p. 15-29 15 p.

Research output: Contribution to journalArticle

Inactivation of viruses by coherent excitations with a low power visible femtosecond laser

Tsen, K. T., Tsen, S. W. D., Chang, C. L., Hung, C. F., Wu, T. C. & Kiang, J. G., Jul 6 2007, In : Virology Journal. 4, 50.

Research output: Contribution to journalArticle

Inactivation of viruses by laser-driven coherent excitations via impulsive stimulated Raman scattering process

Tsen, K. T., Tsen, S. W. D., Chang, C. L., Hung, C. F., Wu, T. C. & Kiang, J. G., Dec 1 2007, In : Journal of biomedical optics. 12, 6, 064030.

Research output: Contribution to journalArticle

Inactivation of viruses with a very low power visible femtosecond laser

Tsen, K. T., Tsen, S. W. D., Chang, C. L., Hung, C. F., Wu, T. C. & Kiang, J. G., Aug 15 2007, In : Journal of Physics Condensed Matter. 19, 32, 322102.

Research output: Contribution to journalArticle