Tzyy Choou Wu

Professor

1986 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2010

DNA vaccine with α-galactosylceramide at prime phase enhances anti-tumor immunity after boosting with antigen-expressing dendritic cells

Kim, D., Hung, C. F., Wu, T. C. & Park, Y. M., Oct 21 2010, In : Vaccine. 28, 45, p. 7297-7305 9 p.

Research output: Contribution to journalArticle

Ectopic expression of X-linked lymphocyte-regulated protein pM1 renders tumor cells resistant to antitumor immunity

Kang, T. H., Noh, K. H., Kim, J. H., Bae, H. C., Lin, K. Y., Monie, A., Pai, S. I., Hung, C. F., Wu, T. C. & Kim, T. W., Apr 15 2010, In : Cancer Research. 70, 8, p. 3062-3070 9 p.

Research output: Contribution to journalArticle

Efficient delivery of DNA vaccines using human papillomavirus pseudovirions

Peng, S., Monie, A., Kang, T. H., Hung, C. F., Roden, R. & Wu, T. C., Dec 1 2010, In : Gene Therapy. 17, 12, p. 1453-1464 12 p.

Research output: Contribution to journalArticle

Enhancing DNA vaccine potency by co-administration of xenogenic MHC class-I DNA

Kang, T. H., Chung, J. Y., Monie, A., Pai, S. I., Hung, C. F. & Wu, T. C., Apr 1 2010, In : Gene Therapy. 17, 4, p. 531-540 10 p.

Research output: Contribution to journalArticle

Enhancing the therapeutic effect against ovarian cancer through a combination of viral oncolysis and antigen-specific immunotherapy

Zhang, Y. Q., Tsai, Y. C., Monie, A., Wu, T. C. & Hung, C. F., Apr 1 2010, In : Molecular Therapy. 18, 4, p. 692-699 8 p.

Research output: Contribution to journalArticle

HPV and therapeutic vaccines: Where are we in 2010?

Ma, B., Xu, Y., Hung, C. F. & Wu, T. C., Jun 4 2010, In : Current Cancer Therapy Reviews. 6, 2, p. 81-103 23 p.

Research output: Contribution to journalArticle

Immunotherapy for cervical cancer: Research status and clinical potential

Su, J. H., Wu, A., Scotney, E., Ma, B., Monie, A., Hung, C. F. & Wu, T. C., Mar 15 2010, In : BioDrugs. 24, 2, p. 109-129 21 p.

Research output: Contribution to journalReview article

Improving therapeutic HPV peptide-based vaccine potency by enhancing CD4+ T help and dendritic cell activation

Wu, C. Y., Monie, A., Pang, X., Hung, C. F. & Wu, T. C., Nov 25 2010, In : Journal of biomedical science. 17, 1, 88.

Research output: Contribution to journalArticle

Inhibitory RNA molecules in immunotherapy for cancer.

Mao, C. P. & Wu, T. C., 2010, In : Methods in molecular biology (Clifton, N.J.). 623, p. 325-339 15 p.

Research output: Contribution to journalArticle

Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3

Trimble, C. L., Peng, S., Thoburn, C., Kos, F. & Wu, T. C., May 2010, In : Cancer Immunology, Immunotherapy. 59, 5, p. 799-803 5 p.

Research output: Contribution to journalArticle

Perspectives for Preventive and Therapeutic HPV Vaccines

Lin, K., Doolan, K., Hung, C. F. & Wu, T. C., Jan 2010, In : Journal of the Formosan Medical Association. 109, 1, p. 4-24 21 p.

Research output: Contribution to journalReview article

Photonic approach to the selective inactivation of viruses with a near-infrared ultrashort pulsed laser

Tsen, K. T., Tsen, S. W. D., Fu, Q., Lindsay, S. M., Kibler, K., Jacobs, B., Wu, T. C., Li, Z., Yan, H., Cope, S., Vaiana, S. & Kiang, J. G., 2010, Optical Biopsy VII. 75610W. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7561).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Selective inactivation of viruses with femtosecond laser pulses and its potential use for in vitro therapy

Tsen, S. W. D., Tsen, Y. S. D., Tsen, K. T. & Wu, T. C., Jun 2010, In : Journal of Healthcare Engineering. 1, 2, p. 185-196 12 p.

Research output: Contribution to journalArticle

Therapeutic HPV DNA vaccines

Lin, K., Roosinovich, E., Ma, B., Hung, C. F. & Wu, T. C., Jul 1 2010, In : Immunologic Research. 47, 1-3, p. 86-112 27 p.

Research output: Contribution to journalReview article

Treatment with Imiquimod enhances antitumor immunity induced by therapeutic HPV DNA vaccination

Chuang, C. M., Monie, A., Hung, C. F. & Wu, T. C., 2010, In : Journal of biomedical science. 17, 1, 32.

Research output: Contribution to journalArticle

2011

Control of cervicovaginal HPV-16 E7-expressing tumors by the combination of therapeutic HPV vaccination and vascular disrupting agents

Zeng, Q., Peng, S., Monie, A., Yang, M., Pang, X., Hung, C. F. & Wu, T. C., Jul 1 2011, In : Human gene therapy. 22, 7, p. 809-819 11 p.

Research output: Contribution to journalArticle

Enforced expression of miR-101 inhibits prostate cancer cell growth by modulating the COX-2 pathway in vivo

Hao, Y., Gu, X., Zhao, Y., Greene, S., Sha, W., Smoot, D. T., Califano, J., Wu, T. C. & Pang, X., Jul 2011, In : Cancer Prevention Research. 4, 7, p. 1073-1083 11 p.

Research output: Contribution to journalArticle

Enhancement of protein vaccine potency by in vivo electroporation mediated intramuscular injection

Kang, T. H., Monie, A., Wu, L. S. F., Pang, X., Hung, C. F. & Wu, T. C., Jan 29 2011, In : Vaccine. 29, 5, p. 1082-1089 8 p.

Research output: Contribution to journalArticle

HPV pseudovirions as DNA delivery vehicles

Ma, B., Roden, R. B. S., Hung, C. F. & Wu, T. C., Apr 1 2011, In : Therapeutic Delivery. 2, 4, p. 427-430 4 p.

Research output: Contribution to journalEditorial

Improvement of prostate cancer detection by integrating the PSA test with miRNA expression profiling

Hao, Y., Zhao, Y., Zhao, X., He, C., Pang, X., Wu, T. C., Califano, J. A. & Gu, X., May 2011, In : Cancer Investigation. 29, 4, p. 318-324 7 p.

Research output: Contribution to journalArticle

Intraperitoneal administration of poly(I:C) with polyethylenimine leads to significant antitumor immunity against murine ovarian tumors

Wu, C. Y., Yang, H. Y., Monie, A., Ma, B., Tsai, H. H., Wu, T. C. & Hung, C. F., Aug 2011, In : Cancer Immunology, Immunotherapy. 60, 8, p. 1085-1096 12 p.

Research output: Contribution to journalArticle

In vivo microRNA-155 expression influences antigen-specific T cell-mediated immune responses generated by DNA vaccination

Mao, C. P., He, L., Tsai, Y. C., Peng, S., Kang, T. H., Pang, X., Monie, A., Hung, C. F. & Wu, T. C., Jan 18 2011, In : Cell and Bioscience. 1, 1, 3.

Research output: Contribution to journalArticle

Molecular pathogenesis, detection and clinical management of pre-invasive cervical lesions

Chen, W. C., Ma, B., Mao, C. P. & Wu, T. C., Dec 1 2011, Pre-Invasive Disease: Pathogenesis and Clinical Management. Springer New York, p. 437-466 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Perspectives on therapeutic HPV vaccines: Where are we now?

Wang, C., Ma, B., Chen, A., Hung, C. F. & Wu, T. C., Sep 1 2011, HPV and Cervical Cancer: Achievements in Prevention and Future Prospects. Springer New York, p. 341-389 49 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes

Heaphy, C. M., Subhawong, A. P., Hong, S. M., Goggins, M. G., Montgomery, E. A., Gabrielson, E., Netto, G. J., Epstein, J. I., Lotan, T. L., Westra, W. H., Shih, I. M., Iacobuzio-Donahue, C. A., Maitra, A., Li, Q. K., Eberhart, C. G., Taube, J. M., Rakheja, D., Kurman, R. J., Wu, T. C., Roden, R. B. & 5 others, Argani, P., De Marzo, A. M., Terracciano, L., Torbenson, M. & Meeker, A. K., Oct 1 2011, In : American Journal of Pathology. 179, 4, p. 1608-1615 8 p.

Research output: Contribution to journalArticle

2012

Cancer vaccination drives nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype

Noh, K. H., Lee, Y. H., Jeon, J. H., Kang, T. H., Mao, C. P., Wu, T. C. & Kim, T. W., Apr 1 2012, In : Cancer Research. 72, 7, p. 1717-1727 11 p.

Research output: Contribution to journalArticle

Development of a DNA vaccine targeting Merkel cell polyomavirus

Zeng, Q., Gomez, B. P., Viscidi, R. P., Peng, S., He, L., Ma, B., Wu, T. C. & Hung, C. F., Feb 8 2012, In : Vaccine. 30, 7, p. 1322-1329 8 p.

Research output: Contribution to journalArticle

Emerging human papillomavirus vaccines

Ma, B., Maraj, B., Tran, N. P., Knoff, J., Chen, A., Alvarez, R. D., Hung, C. F. & Wu, T. C., Dec 1 2012, In : Expert Opinion on Emerging Drugs. 17, 4, p. 469-492 24 p.

Research output: Contribution to journalReview article

Immune mechanism of the antitumor effects generated by bortezomib

Chang, C. L., Hsu, Y. T., Wu, C. C., Yang, Y. C., Wang, C., Wu, T. C. & Hung, C. F., Sep 15 2012, In : Journal of Immunology. 189, 6, p. 3209-3220 12 p.

Research output: Contribution to journalArticle

LAH4 enhances CD8+ T cell immunity of protein/peptide-based vaccines

Zhang, T. T., Kang, T. H., Ma, B., Xu, Y., Hung, C. F. & Wu, T. C., Jan 17 2012, In : Vaccine. 30, 4, p. 784-793 10 p.

Research output: Contribution to journalArticle

Nanog signaling in cancer promotes stem-like phenotype and immune evasion

Noh, K. H., Kim, B. W., Song, K. H., Cho, H., Lee, Y. H., Kim, J. H., Chung, J. Y., Kim, J. H., Hewitt, S. M., Seong, S. Y., Mao, C. P., Wu, T. C. & Kim, T. W., Nov 1 2012, In : Journal of Clinical Investigation. 122, 11, p. 4077-4093 17 p.

Research output: Contribution to journalArticle

OGDHL Is a Modifier of AKT-Dependent Signaling and NF-κB Function

Sen, T., Sen, N., Noordhuis, M. G., Ravi, R., Wu, T. C., Ha, P. K., Sidransky, D. & Hoque, M. O., Nov 12 2012, In : PloS one. 7, 11, e48770.

Research output: Contribution to journalArticle

Ovarian cancer gene therapy using HPV-16 Pseudovirion carrying the HSV-tk gene

Hung, C. F., Chiang, A. J., Tsai, H. H., Pomper, M. G., Kang, T. H., Roden, R. R. & Wu, T. C., Jul 17 2012, In : PloS one. 7, 7, e40983.

Research output: Contribution to journalArticle

Prospects for a novel ultrashort pulsed laser technology for pathogen inactivation

Tsen, S. W. D., Wu, T. C., Kiang, J. G. & Tsen, K. T., 2012, In : Journal of biomedical science. 19, 1, 62.

Research output: Contribution to journalReview article

Side-by-side comparison of gene-based smallpox vaccine with MVA in nonhuman primates

Golden, J. W., Josleyn, M., Mucker, E. M., Hung, C. F., Loudon, P. T., Wu, T. C. & Hooper, J. W., Jul 31 2012, In : PloS one. 7, 7, e42353.

Research output: Contribution to journalArticle

Strategies to improve DNA vaccine potency: HPV-associated cervical cancer as a model system

Hung, C. F., Ma, B., Xu, Y. & Wu, T. C., Mar 1 2012, Gene Vaccines. Springer-Verlag Wien, Vol. 9783709104392. p. 37-65 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tumor-targeted delivery of IL-2 by NKG2D leads to accumulation of antigen-specific CD8+ T cells in the tumor loci and enhanced anti-tumor effects

Kang, T. H., Mao, C. P., He, L., Tsai, Y. C., Liu, K., La, V., Wu, T. C. & Hung, C. F., 2012, In : PloS one. 7, 4, e35141.

Research output: Contribution to journalArticle

2013

A broad survey of cathepsin k immunoreactivity in human neoplasms

Zheng, G., Martignoni, G., Antonescu, C., Montgomery, E., Eberhart, C., Netto, G., Taube, J., Westra, W., Epstein, J. I., Lotan, T., Maitra, A., Gabrielson, E., Torbenson, M., Iacobuzio-Donahue, C., Demarzo, A., Shih, I. M., Illei, P., Wu, T. C. & Argani, P., Feb 1 2013, In : American journal of clinical pathology. 139, 2, p. 151-159 9 p.

Research output: Contribution to journalReview article

Bortezomib enhances antigen-specific cytotoxic T cell responses against immune-resistant cancer cells generated by STAT3-ablated dendritic cells

Kim, J. E., Jin, D. H., Lee, W. J., Hur, D., Wu, T. C. & Kim, D., May 2013, In : Pharmacological Research. 71, p. 23-33 11 p.

Research output: Contribution to journalArticle

Chemotherapy acts as an adjuvant to convert the tumor microenvironment into a highly permissive state for vaccination-induced antitumor immunity

Kang, T. H., Mao, C. P., Lee, S. Y., Chen, A., Lee, J. H., Kim, T. W., Alvarez, R. D., Roden, R. B. S., Pardoll, D., Hung, C. F. & Wu, T. C., Apr 15 2013, In : Cancer Research. 73, 8, p. 2493-2504 12 p.

Research output: Contribution to journalArticle

Control of spontaneous ovarian tumors by CD8+ T cells through NKG2D-targeted delivery of antigenic peptide

Kang, T. H., Knoff, J., Yang, B., Tsai, Y. C., He, L., Hung, C. F. & Wu, T. C., Dec 20 2013, In : Cell and Bioscience. 3, 1, 48.

Research output: Contribution to journalArticle

Dose-dense chemotherapy improves mechanisms of antitumor immune response

Chang, C. L., Hsu, Y. T., Wu, C. C., Lai, Y. Z., Wang, C., Yang, Y. C., Wu, T. C. & Hung, C. F., Jan 1 2013, In : Cancer Research. 73, 1, p. 119-127 9 p.

Research output: Contribution to journalArticle

Erratum: Mucosal imprinting of vaccine-induced CD8+ T cells is crucial to inhibit the growth of mucosal tumors (Science Translational Medicine (2013) 5 (178er2))

Sandoval, F., Terme, M., Nizard, M., Badoual, C., Bureau, M. F., Freyburger, L., Clement, O., Marcheteau, E., Gey, A., Fraisse, G., Bouguin, C., Merillon, N., Dransart, E., Tran, T., Quintin-Colonna, F., Autret, G., Thiebaud, M., Suleman, M., Riffault, S., Wu, T. C. & 8 others, Launay, O., Danel, C., Taieb, J., Richardson, J., Zitvogel, L., Fridman, W. H., Johannes, L. & Tartour, E., Mar 27 2013, In : Science translational medicine. 5, 178, 178er2.

Research output: Contribution to journalComment/debate

Open Access

Histone deacetylase inhibitor AR-42 enhances E7-specific CD8+ T cell-mediated antitumor immunity induced by therapeutic HPV DNA vaccination

Lee, S. Y., Huang, Z., Kang, T. H., Soong, R. S., Knoff, J., Axenfeld, E., Wang, C., Alvarez, R. D., Chen, C. S., Hung, C. F. & Wu, T. C., Oct 2013, In : Journal of Molecular Medicine. 91, 10, p. 1221-1231 11 p.

Research output: Contribution to journalArticle

In memoriam: Kuan-Teh Jeang, MD PhD (1958-2013)

Jin, D. Y., Shi, Y. B. & Wu, T. C., Feb 28 2013, In : Cell and Bioscience. 3, 1, 13.

Research output: Contribution to journalArticle

Innovative DNA vaccine to break immune tolerance against tumor self-antigen

Kang, T. H., Mao, C. P., La, V., Chen, A., Hung, C. F. & Wu, T. C., Feb 1 2013, In : Human gene therapy. 24, 2, p. 181-188 8 p.

Research output: Contribution to journalArticle