Tzyy Choou Wu

Professor

1986 …2020

Research output per year

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Research Output

2007

Moderate reduction of γ-secretase attenuates amyloid burden and limits mechanism-based liabilities

Li, T., Wen, H., Brayton, C., Laird, F. M., Ma, G., Peng, S., Placanica, L., Wu, T. C., Crain, B. J., Price, D. L., Eberhart, C. G. & Wong, P. C., Oct 3 2007, In : Journal of Neuroscience. 27, 40, p. 10849-10859 11 p.

Research output: Contribution to journalArticle

Opportunities to improve the prevention and treatment of cervical cancer

Roden, R. B. S., Monie, A. & Wu, T. C., Aug 1 2007, In : Current Molecular Medicine. 7, 5, p. 490-503 14 p.

Research output: Contribution to journalReview article

Preventive and therapeutic HPV vaccines

Monie, A., Hung, C. F. & Wu, T. C., Dec 12 2007, In : Current Opinion in Investigational Drugs. 8, 12, p. 1038-1050 13 p.

Research output: Contribution to journalReview article

Regulatory T cells: Potential target in anticancer immunotherapy

Juang, C. M., Hung, C. F., Yeh, J. Y., Horng, H. C., Twu, N. F., Cheng, M. H., Wen, K. C., Yuan, C. C., Chao, K. C., Wu, T. C. & Yen, M. S., Sep 2007, In : Taiwanese Journal of Obstetrics and Gynecology. 46, 3, p. 215-221 7 p.

Research output: Contribution to journalReview article

Therapeutic human papillomavirus DNA vaccination strategies to control cervical cancer

Wu, T. C., Feb 2007, In : European Journal of Immunology. 37, 2, p. 310-314 5 p.

Research output: Contribution to journalComment/debate

The role of vascular cell adhesion molecule-1 in tumor immune evasion

Wu, T. C., Jul 1 2007, In : Cancer Research. 67, 13, p. 6003-6006 4 p.

Research output: Contribution to journalReview article

Vaccines against human papillomavirus

Lin, Y. Y., Alphs, H., Hung, C. F., Roden, R. B. S. & Wu, T. C., Jun 7 2007, In : Frontiers in Bioscience. 12, 1, p. 246-264 19 p.

Research output: Contribution to journalArticle

Vaccinia virus preferentially infects and controls human and murine ovarian tumors in mice

Hung, C. F., Tsai, Y. C., He, L., Coukos, G., Fodor, I., Qin, L., Levitsky, H. & Wu, T. C., Jan 1 2007, In : Gene Therapy. 14, 1, p. 20-29 10 p.

Research output: Contribution to journalArticle

2008

Anti-gene padlocks eliminate Escherichia coli based on their genotype

Shi, C., Parker, A. R., Hua, L., Morrell, C. N., Lee, S. C., Bandaru, V., Dumler, J. S., Wu, T. C. & Eshleman, J. R., Feb 1 2008, In : Journal of Antimicrobial Chemotherapy. 61, 2, p. 262-272 11 p.

Research output: Contribution to journalArticle

Antigen-specific immunotherapy of cervical and ovarian cancer

Hung, C. F., Wu, T. C., Monie, A. & Roden, R., Apr 2008, In : Immunological reviews. 222, 1, p. 43-69 27 p.

Research output: Contribution to journalReview article

Cervarix™:A vaccine for the prevention of HPV 16, 18-associated cervical cancer

Monie, A., Hung, C. F., Roden, R. & Wu, T. C., Dec 1 2008, In : Biologics: Targets and Therapy. 2, 1, p. 107-113 7 p.

Research output: Contribution to journalReview article

Cluster intradermal DNA vaccination rapidly induces E7-specific CD8+ T-cell immune responses leading to therapeutic antitumor effects

Peng, S., Trimble, C., Alvarez, R. D., Huh, W. K., Lin, Z., Monie, A., Hung, C. F. & Wu, T. C., Aug 13 2008, In : Gene Therapy. 15, 16, p. 1156-1166 11 p.

Research output: Contribution to journalArticle

Combination of treatment with death receptor 5-specific antibody with therapeutic HPV DNA vaccination generates enhanced therapeutic anti-tumor effects

Tseng, C. W., Monie, A., Trimble, C., Alvarez, R. D., Huh, W. K., Buchsbaum, D. J., Straughn, J. M., Wang, M. C., Yagita, H., Hung, C. F. & Wu, T. C., Aug 12 2008, In : Vaccine. 26, 34, p. 4314-4319 6 p.

Research output: Contribution to journalArticle

Enhancement of antibody responses to Bacillus anthracis protective antigen domain IV by use of calreticulin as a chimeric molecular adjuvant

Yong, S. P., Jin, H. L., Hung, C. F., Wu, T. C. & Tae, W. K., May 2008, In : Infection and immunity. 76, 5, p. 1952-1959 8 p.

Research output: Contribution to journalArticle

Enhancement of CD4+ T-cell help reverses the doxorubicin-induced suppression of antigen-specific immune responses in vaccinated mice

Kim, D., Monie, A., Tsai, Y. C., He, L., Wang, M. C., Hung, C. F. & Wu, T. C., Aug 13 2008, In : Gene Therapy. 15, 16, p. 1176-1183 8 p.

Research output: Contribution to journalArticle

Enhancement of DNA vaccine potency through coadministration of CIITA DNA with DNA vaccines via gene gun

Kim, D., Hoory, T., Monie, A., Ting, J. P. Y., Hung, C. F. & Wu, T. C., 2008, In : Journal of Immunology. 180, 10, p. 7019-7027 9 p.

Research output: Contribution to journalArticle

Open Access

Generation and characterization of a preventive and therapeutic HPV DNA vaccine

Kim, D., Gambhira, R., Karanam, B., Monie, A., Hung, C. F., Roden, R. & Wu, T. C., Jan 17 2008, In : Vaccine. 26, 3, p. 351-360 10 p.

Research output: Contribution to journalArticle

Immunotherapy of angiogenesis with DNA vaccines

Hung, C. F., Monie, A. & Wu, T. C., Dec 1 2008, Angiogenesis: An Integrative Approach From Science to Medicine. Springer US, p. 451-460 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Inactivation of viruses with a femtosecond laser via impulsive stimulated Raman scattering

Tsen, K. T., Tsen, S. W. D., Chang, C. L., Hung, C. F., Wu, T. C., Ramakrishna, B., Mossman, K. & Kiang, J. G., Apr 21 2008, Optical Interactions with Tissue and Cells XIX. 68540N. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 6854).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Inhibition of tumor growth by NK1.1+ cells and CD8+ T cells activated by IL-15 through receptor β/common γ signaling in trans

Rowley, J., Monie, A., Hung, C. F. & Wu, T. C., Dec 15 2008, In : Journal of Immunology. 181, 12, p. 8237-8247 11 p.

Research output: Contribution to journalArticle

Open Access

Molecular epidemiology of human papillomavirus

Hoory, T., Monie, A., Gravitt, P. & Wu, T. C., Mar 2008, In : Journal of the Formosan Medical Association. 107, 3, p. 198-217 20 p.

Research output: Contribution to journalReview article

News and EFIS

Roden, R. B. S., Gravitt, P. & Wu, T. C., Feb 1 2008, In : European Journal of Immunology. 38, 2, p. 323-326 4 p.

Research output: Contribution to journalArticle

Pretreatment with cisplatin enhances E7-Specific CD8+ T-cell -mediated antitumor immunity induced by DNA vaccination

Tseng, C. W., Hung, C. F., Alvarez, R. D., CorneliaTrimble, Huh, W. K., Kim, D., Chuang, C. M., Lin, C. T., Tsai, Y. C., He, L., Monie, A. & T-CWu, May 15 2008, In : Clinical Cancer Research. 14, 10, p. 3185-3192 8 p.

Research output: Contribution to journalArticle

RNA interference-mediated in vivo silencing of Fas ligand as a strategy for the enhancement of DNA vaccine potency

Huang, B., Mao, C. P., Peng, S., Hung, C. F. & Wu, T. C., Aug 1 2008, In : Human gene therapy. 19, 8, p. 763-773 11 p.

Research output: Contribution to journalArticle

Role of IL-2 secreted by PADRE-specific CD4+ T cells in enhancing E7-specific CD8+ T-cell immune responses

Kim, D., Monie, A., He, L., Tsai, Y. C., Hung, C. F. & Wu, T. C., May 2008, In : Gene Therapy. 15, 9, p. 677-687 11 p.

Research output: Contribution to journalArticle

Selective inactivation of human immunodeficiency virus with subpicosecond near-infrared laser pulses

Tsen, K. T., Tsen, S. W. D., Hung, C. F., Wu, T. C. & Kiang, J. G., Jun 25 2008, In : Journal of Physics Condensed Matter. 20, 25, 252205.

Research output: Contribution to journalArticle

Therapeutic human papillomavirus vaccines: Current clinical trials and future directions

Hung, C. F., Ma, B., Monie, A., Tsen, S. W. & Wu, T. C., Apr 2008, In : Expert Opinion on Biological Therapy. 8, 4, p. 421-439 19 p.

Research output: Contribution to journalReview article

The role of vascular cell adhesion molecule-1 in tumor immune evasion

Wu, T. C., Feb 1 2008, In : Journal of Urology. 179, 2, 1 p.

Research output: Contribution to journalComment/debate

Treatment with proteasome inhibitor bortezomib enhances antigen-specific CD8+ T-cell-mediated antitumor immunity induced by DNA vaccination

Tseng, C. W., Monie, A., Wu, C. Y., Huang, B., Wang, M. C., Hung, C. F. & Wu, T. C., Aug 1 2008, In : Journal of Molecular Medicine. 86, 8, p. 899-908 10 p.

Research output: Contribution to journalArticle

2009

Activation of Akt as a mechanism for tumor immune evasion

Noh, K. H., Kang, T. H., Kim, J. H., Pai, S. I., Lin, K. Y., Hung, C. F., Wu, T. C. & Kim, T. W., Jan 1 2009, In : Molecular Therapy. 17, 3, p. 439-447 9 p.

Research output: Contribution to journalArticle

Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery

Best, S. R., Peng, S., Juang, C. M., Hung, C. F., Hannaman, D., Saunders, J. R., Wu, T. C. & Pai, S. I., Sep 4 2009, In : Vaccine. 27, 40, p. 5450-5459 10 p.

Research output: Contribution to journalArticle

A phase I trial of a human papillomavirus DNA vaccine for HPV16+Cervical intraepithelial neoplasia 2/3

Trimble, C. L., Peng, S., Kos, F., Gravitt, P., Viscidi, R., Sugar, E., Pardoll, D. & Wu, T. C., Jan 1 2009, In : Clinical Cancer Research. 15, 1, p. 361-367 7 p.

Research output: Contribution to journalArticle

DNA Vaccines for the Human Papilloma Virus

Ma, B., Hung, C. F. & Wu, T. C., Oct 27 2009, Tumor-Associated Antigens: Identification, Characterization, and Clinical Applications. Wiley-VCH Verlag GmbH & Co. KGaA, p. 317-337 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Expression of IL-15RA or an IL-15/IL-15RA fusion on CD8+ T cells modifies adoptively transferred T-cell function in cis

Rowley, J., Monie, A., Hung, C. F. & Wu, T. C., 2009, In : European Journal of Immunology. 39, 2, p. 491-506 16 p.

Research output: Contribution to journalArticle

Femtosecond laser treatment enhances DNA transfection efficiency in vivo

Tsen, S. W. D., Wu, C. Y., Meneshian, A., Pai, S. I., Hung, C. F. & Wu, T. C., 2009, In : Journal of biomedical science. 16, 1, 36.

Research output: Contribution to journalArticle

Low-dose radiation enhances therapeutic HPV DNA vaccination in tumor-bearing hosts

Tseng, C. W., Trimble, C., Zeng, Q., Monie, A., Alvarez, R. D., Huh, W. K., Hoory, T., Wang, M. C., Hung, C. F. & Wu, T. C., May 1 2009, In : Cancer Immunology, Immunotherapy. 58, 5, p. 737-748 12 p.

Research output: Contribution to journalArticle

Modification of dendritic cells to enhance cancer vaccine potency

Monie, A., Hung, C. F. & Wu, T. C., Dec 1 2009, Targeted Cancer Immune Therapy. Springer New York, p. 133-157 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Photonic approach to the selective inactivation of viruses with a near-infrared subpicosecond fiber laser

Tsen, K. T., Tsen, S. W. D., Fu, Q., Lindsay, S. M., Kibler, K., Jacobs, B., Wu, T. C., Karanam, B., Jagu, S., Roden, R. B. S., Hung, C. F., Sankey, O. F., Ramakrishna, B. & Kiang, J. G., 2009, In : Journal of biomedical optics. 14, 6, 064042.

Research output: Contribution to journalArticle

Selective inactivation of Human Immunodeficiency Virus with an ultrashort pulsed laser

Tsen, K. T., Tsen, S. W. D., Hung, C. F., Wu, T. C., Kibler, K., Jacobs, B. & Kiang, J. G., May 5 2009, In : Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 7175, 717510.

Research output: Contribution to journalConference article

Therapeutic HPV DNA vaccines

Monie, A., Tsen, S. W. D., Hung, C. F. & Wu, T. C., Sep 1 2009, In : Expert review of vaccines. 8, 9, p. 1221-1235 15 p.

Research output: Contribution to journalReview article

Treatment with cyclooxygenase-2 inhibitors enables repeated administration of vaccinia virus for vontrol of ovarian cancer

Chang, C. L., Ma, B., Pang, X., Wu, T. C. & Hung, C. F., Jun 3 2009, In : Molecular Therapy. 17, 8, p. 1365-1372 8 p.

Research output: Contribution to journalArticle

2010

Carrageenan as an adjuvant to enhance peptide-based vaccine potency

Zhang, Y. Q., Tsai, Y. C., Monie, A., Hung, C. F. & Wu, T. C., Jul 1 2010, In : Vaccine. 28, 32, p. 5212-5219 8 p.

Research output: Contribution to journalArticle

Characterization of human papillomavirus type 11-specific immune responses in a preclinical model

Peng, S., Best, S. R., Hung, C. F., Loyo, M., Lyford-Pike, S., Flint, P. W., Tunkel, D. E., Saunders, J. R., Wu, T. C. & Pai, S. I., Mar 2010, In : Laryngoscope. 120, 3, p. 504-510 7 p.

Research output: Contribution to journalArticle

Combined administration with DNA encoding vesicular stomatitis virus G protein enhances DNA vaccine potency

Mao, C. P., Hung, C. F., Kang, T. H., He, L., Tsai, Y. C., Wu, C. Y. & Wu, T. C., Mar 2010, In : Journal of virology. 84, 5, p. 2331-2339 9 p.

Research output: Contribution to journalArticle

Current status of human papillomavirus vaccines.

Ma, B., Roden, R. & Wu, T. C., Jul 2010, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 109, 7, p. 481-483 3 p.

Research output: Contribution to journalComment/debate

DNA vaccines for cervical cancer

Huang, C. F., Monie, A., Weng, W. H. & Wu, T. C., Feb 19 2010, In : American Journal of Translational Research. 2, 1, p. 75-87 13 p.

Research output: Contribution to journalReview article