Tzyy Choou Wu

Professor

1986 …2020

Research output per year

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Research Output

1998

Generation of type-specific probes for the detection of single-copy human papillomavirus by a novel in situ hybridization method

Huang, C. C., Qiu, J. T., Kashima, M. L., Kurman, R. J. & Wu, T. C., Oct 1 1998, In : Modern Pathology. 11, 10, p. 971-977 7 p.

Research output: Contribution to journalArticle

1999

Gene gun-mediated DNA vaccination induces antitumor immunity against human papillomavirus type 16 E7-expressing murine tumor metastases in the liver and lungs

Chen, C. H., Ji, H., Suh, K. W., Choti, M. A., Pardoll, D. M. & Wu, T. C., Dec 1 1999, In : Gene Therapy. 6, 12, p. 1972-1981 10 p.

Research output: Contribution to journalArticle

Generation of type-specific probes for the detection of single-copy human papillomavirus by a novel in situ hybridization method (multiple letters)

Huang, C. C., Qui, J. T., Kashima, M. L., Kurman, R. J., Wu, T. C., Nuovo, G. & Wu, C., Jan 1 1999, In : Modern Pathology. 12, 7, p. 744-745 2 p.

Research output: Contribution to journalLetter

Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver

Rashid, A., Wu, T. C., Huang, C. C., Chen, C. H., Lin, H. Z., Yang, S. Q., Lee, F. Y. J. & Diehl, A. M., Jan 1 1999, In : Hepatology. 29, 4, p. 1131-1138 8 p.

Research output: Contribution to journalArticle

Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion

Chavin, K. D., Yang, S. Q., Lin, H. Z., Chatham, J., Chacko, V. P., Hock, J. B., Walajtys-Rode, E., Rashid, A., Chen, C. H., Huang, C. C., Wu, T. C., Lane, M. D. & Diehl, A. M., Feb 26 1999, In : Journal of Biological Chemistry. 274, 9, p. 5692-5700 9 p.

Research output: Contribution to journalArticle

2000

Antigen-specific cancer immunotherapy using a GM-CSF secreting allogeneic tumor cell-based vaccine

Chang, E. Y., Chen, C. H., Ji, H., Wang, T. L., Hung, K., Lee, B. P., Huang, A. Y. C., Kurman, R. J., Pardoll, D. M. & Wu, T. C., 2000, In : International Journal of Cancer. 86, 5, p. 725-730 6 p.

Research output: Contribution to journalArticle

Antigen-specific immunotherapy for human papillomavirus 16 E7-expressing tumors grown in the liver

Chen, C. H., Suh, K. W., Ji, H., Choti, M. A., Pardoll, D. M. & Wu, T. C., Jul 2000, In : Journal of Hepatology. 33, 1, p. 91-98 8 p.

Research output: Contribution to journalArticle

Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene

Chen, C. H., Wang, T. L., Hung, C. F., Yang, Y., Young, R. A., Pardoll, D. M. & Wu, T. C., Feb 15 2000, In : Cancer Research. 60, 4, p. 1035-1042 8 p.

Research output: Contribution to journalArticle

Granulocyte-macrophage colony-stimulating factor priming plus papillomavirus E6 DNA vaccination: Effects on papilloma formation and regression in the cottontail rabbit papillomavirus-rabbit model

Leachman, S. A., Tigelaar, R. E., Shlyankevich, M., Slade, M. D., Irwin, M., Chang, E., Wu, T. C., Xiao, W., Pazhani, S., Zelterman, D. & Brandsma, J. L., Sep 13 2000, In : Journal of virology. 74, 18, p. 8700-8708 9 p.

Research output: Contribution to journalArticle

Immunotherapy of a human papillomavirus type 16 E7-expressing tumor by administration of fusion protein comprised of Mycobacterium bovis BCG Hsp65 and HPV16 E7

Chu, N. R., Wu, H. B., Wu, T. C., Boux, L. J., Mizzen, L. A. & Siegel, M. I., 2000, In : Cell Stress and Chaperones. 5, 5, p. 401-405 5 p.

Research output: Contribution to journalArticle

Intramuscular administration of E7-transfected dendritic cells generates the most potent E7-specific anti-tumor immunity

Wang, T. L., Ling, M., Shih, I. M., Pham, T., Pai, S. I., Lu, Z., Kurman, R. J., Pardoll, D. M. & Wu, T. C., May 2000, In : Gene Therapy. 7, 9, p. 726-733 8 p.

Research output: Contribution to journalArticle

Open Access

Investigation of the association of esophageal carcinoma with human papillomaviruses

Kamath, Wu, Heitmiller, Daniel & Shah, 2000, In : Diseases of the Esophagus. 13, 2, p. 122-124 3 p.

Research output: Contribution to journalArticle

Preventive and therapeutic vaccines for human papillomavirus-associated cervical cancers

Ling, M., Kanayama, M., Roden, R. & Wu, T. C., Jan 1 2000, In : Journal of biomedical science. 7, 5, p. 341-356 16 p.

Research output: Contribution to journalReview article

2001

Cancer immunotherapy using a DNA vaccine encoding the translocation domain of a bacterial toxin linked to a tumor antigen

Hung, C. F., Cheng, W. F., Hsu, K. F., Chai, C. Y., He, L., Ling, M. & Wu, T. C., May 1 2001, In : Cancer Research. 61, 9, p. 3698-3703 6 p.

Research output: Contribution to journalArticle

Congenital prepubic sinus: A variant of dorsal urethral duplication suggested by immunohistochemical analysis

Huang, C. C., Wu, W. H., Chai, C. Y., Wu, T. C. & Chuang, J. H., Jan 1 2001, In : Journal of Urology. 166, 5, p. 1876-1879 4 p.

Research output: Contribution to journalArticle

Enhancement of DNA vaccine potency by linkage of antigen gene to a gene encoding the extracellular domain of Fms-like tyrosine kinase 3-ligand

Hung, C. F., Hsu, K. F., Cheng, W. F., Chai, C. Y., He, L., Ling, M. & Wu, T. C., 2001, In : Cancer Research. 61, 3, p. 1080-1088 9 p.

Research output: Contribution to journalArticle

Enhancement of Sindbis virus self-replicating RNA vaccine potency by linkage of herpes simplex virus type 1 VP22 protein to antigen

Cheng, W. F., Hung, C. F., Chai, C. Y., Hsu, K. F., He, L., Ling, M. & Wu, T. C., 2001, In : Journal of virology. 75, 5, p. 2368-2376 9 p.

Research output: Contribution to journalArticle

Enhancement of sindbis virus self-replicating RNA vaccine potency by linkage of Mycobacterium tuberculosis heat shock protein 70 gene to an antigen gene

Cheng, W. F., Hung, C. F., Chai, C. Y., Hsu, K. F., He, L., Rice, C. M., Ling, M. & Wu, T. C., May 15 2001, In : Journal of Immunology. 166, 10, p. 6218-6226 9 p.

Research output: Contribution to journalArticle

Open Access

Enhancement of sindbis virus self-replicating RNA vaccine potency by targeting antigen to endosomal/lysosomal compartments

Cheng, W. F., Hung, C. F., Hsu, K. F., Chai, C. Y., He, L., Ling, M., Slater, L. A., Roden, R. B. S. & Wu, T. C., Feb 10 2001, In : Human gene therapy. 12, 3, p. 235-252 18 p.

Research output: Contribution to journalArticle

Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen

Hsu, K. F., Hung, C. F., Cheng, W. F., He, L., Slater, L. A., Ling, M. & Wu, T. C., Apr 7 2001, In : Gene Therapy. 8, 5, p. 376-383 8 p.

Research output: Contribution to journalArticle

Improving vaccine potency through intercellular spreading and enhanced MHC class I presentation of antigen

Hung, C. F., Cheng, W. F., Chai, C. Y., Hsu, K. F., He, L., Ling, M. & Wu, T. C., May 1 2001, In : Journal of Immunology. 166, 9, p. 5733-5740 8 p.

Research output: Contribution to journalArticle

Recombinant DNA vaccines protect against tumors that are resistant to recombinant vaccinia vaccines containing the same gene

Chen, C. H., Wang, T. L., Ji, H., Hung, C. F., Pardoll, D. M., Cheng, W. F., Ling, M. & Wu, T. C., Feb 28 2001, In : Gene Therapy. 8, 2, p. 128-138 11 p.

Research output: Contribution to journalArticle

Tetra-O-methyl nordihydroguaiaretic acid induces G2 arrest in mammalian cells and exhibits tumoricidal activity in vivo

Heller, J. D., Kuo, J., Wu, T. C., Kast, W. M. & Huang, R. C. C., Jul 15 2001, In : Cancer Research. 61, 14, p. 5499-5504 6 p.

Research output: Contribution to journalArticle

Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen

Cheng, W. F., Hung, C. F., Chai, C. Y., Hsu, K. F., He, L., Ling, M. & Wu, T. C., Oct 9 2001, In : Journal of Clinical Investigation. 108, 5, p. 669-678 10 p.

Research output: Contribution to journalArticle

Open Access
2002

Cancer immunotherapy using sindbis virus replicon particles encoding a VP22-antigen fusion

Cheng, W. F., Hung, C. F., Hsu, K. F., Chai, C. Y., He, L., Polo, J. M., Slater, L. A., Ling, M. & Wu, T. C., Mar 1 2002, In : Human gene therapy. 13, 4, p. 553-568 16 p.

Research output: Contribution to journalArticle

Improving DNA vaccine potency by linking Marek's disease virus type 1 VP22 to an antigen

Hung, C. F., He, L., Juang, J., Lin, T. J., Ling, M. & Wu, T. C., 2002, In : Journal of virology. 76, 6, p. 2676-2682 7 p.

Research output: Contribution to journalArticle

Repeated DNA vaccinations elicited qualitatively different cytotoxic T lymphocytes and improved protective antitumor effects

Cheng, W. F., Hung, C. F., Pai, S. I., Hsu, K. F., He, L., Ling, M. & Wu, T. C., Jan 1 2002, In : Journal of biomedical science. 9, 6, p. 675-687 13 p.

Research output: Contribution to journalArticle

2003

Boosting with recombinant vaccinia increases HPV-16 E7-specific T cell precursor frequencies and antitumor effects of HPV-16 E7-expressing sindbis virus replicon particles

Lin, C. T., Hung, C. F., Juang, J., He, L., Lin, K. Y., Kim, T. W. & Wu, T. C., Oct 2003, In : Molecular Therapy. 8, 4, p. 559-566 8 p.

Research output: Contribution to journalArticle

CD8+ T cells, NK cells and IFN-γ are important for control of tumor with downregulated MHC class I expression by DNA vaccination

Cheng, W. F., Hung, C. F., Lin, K. Y., Ling, M., Juang, J., He, L., Lin, C. T. & Wu, T. C., Aug 1 2003, In : Gene Therapy. 10, 16, p. 1311-1320 10 p.

Research output: Contribution to journalReview article

Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe

Trimble, C., Lin, C. T., Hung, C. F., Pai, S., Juang, J., He, L., Gillison, M., Pardoll, D., Wu, L. & Wu, T. C., Jan 1 2003, In : Vaccine. 21, 25-26, p. 4036-4042 7 p.

Research output: Contribution to journalArticle

Development of HPV vaccines for HPV-associated head and neck squamous cell carcinoma

Devaraj, K., Gillison, M. L. & Wu, T. C., Dec 1 2003, In : Critical Reviews in Oral Biology and Medicine. 14, 5, p. 345-362 18 p.

Research output: Contribution to journalReview article

DNA vaccines for cancer

Boyd, D. A. K., Hung, C. F. & Wu, T. C., Dec 1 2003, In : IDrugs. 6, 12, p. 1155-1164 10 p.

Research output: Contribution to journalReview article

Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins

Kim, T. W., Hung, C. F., Ling, M., Juang, J., He, L., Hardwick, J. M., Kumar, S. & Wu, T. C., Jul 2003, In : Journal of Clinical Investigation. 112, 1, p. 109-117 9 p.

Research output: Contribution to journalArticle

Enhancing DNA vaccine potency by combining a strategy to prolong dendritic cell life with intracellular targeting strategies

Kim, T. W., Hung, C. F., Boyd, D., Juang, J., He, L., Kim, J. W., Hardwick, J. M. & Wu, T. C., Sep 15 2003, In : Journal of Immunology. 171, 6, p. 2970-2976 7 p.

Research output: Contribution to journalArticle

Open Access

Enhancing major histocompatibility complex class I antigen presentation by targeting antigen to centrosomes

Hung, C. F., Cheng, W. F., He, L., Ling, M., Juang, J., Lin, C. T. & Wu, T. C., May 15 2003, In : Cancer Research. 63, 10, p. 2393-2398 6 p.

Research output: Contribution to journalArticle

HPV-16 vaccine prevented persistent HPV-16 infection and the development of HPV-16 related cervical neoplasia

Koutsky, L. A., Ault, K. A., Wheeler, C. M., Brown, D. R., Barr, E., Alvarez, F. B., Chiacchierini, L. M., Jansen, K. U., Wu, T. C. & Boyd, D., Mar 2003, In : Evidence-based Obstetrics and Gynecology. 5, 1, p. 42-43 2 p.

Research output: Contribution to journalShort survey

HPV DNA vaccines

Moniz, M., Ling, M., Hung, C. F. & Wu, T. C., Dec 1 2003, In : Frontiers in Bioscience. 8, p. d55-d68

Research output: Contribution to journalReview article

Improving DNA vaccine potency via modification of professional antigen presenting cells

Hung, C. F. & Wu, T. C., Feb 1 2003, In : Current Opinion in Molecular Therapeutics. 5, 1, p. 20-24 5 p.

Research output: Contribution to journalReview article

Innovations in Understanding the Biology of Cervical Cancer

Wolf, J. K., Franco, E. L., Arbeit, J. M., Shroyer, K. R., Wu, T. C., Runowicz, C. D., Tortolero-Luna, G., Herrero, R. & Crum, C. P., Nov 1 2003, In : Cancer. 98, 9 SUPPL., p. 2064-2069 6 p.

Research output: Contribution to journalArticle

Preventative and therapeutic vaccines for cervical cancer

Roden, R. & Wu, T. C., Aug 1 2003, In : Expert review of vaccines. 2, 4, p. 495-516 22 p.

Research output: Contribution to journalReview article

2004

A DNA vaccine co-expressing antigen and an anti-apoptotic molecule further enhances the antigen-specific CD8+ T-cell immune response

Kim, T. W., Hung, C. F., Zheng, M., Boyd, D. A. K., He, L., Pai, S. I. & Wu, T. C., Jun 15 2004, In : Journal of biomedical science. 11, 4, p. 493-499 7 p.

Research output: Contribution to journalArticle

Comparison of HPV DNA vaccines employing intracellular targeting strategies

Kim, J. W., Hung, C. F., Juang, J., He, T., Kim, T. W., Armstrong, D. K., Pai, S. I., Chen, P. J., Lin, C. T., Boyd, D. A. & Wu, T. C., Jun 1 2004, In : Gene Therapy. 11, 12, p. 1011-1018 8 p.

Research output: Contribution to journalArticle

Development of a DNA vaccine targeting human papillomavirus type 16 oncoprotein E6

Peng, S., Ji, H., Trimble, C., He, L., Tsai, Y. C., Yeatermeyer, J., Boyd, D. A. K., Hung, C. F. & Wu, T. C., Aug 2004, In : Journal of virology. 78, 16, p. 8468-8476 9 p.

Research output: Contribution to journalArticle