Timothy Osborne

2023

Carbon dioxide regulates cholesterol levels through SREBP2

Bolshette, N., Ezagouri, S., Dandavate, V., Karavaeva, I., Golik, M., Wang, H., Espenshade, P. J., Osborne, T. F., Han, X. & Asher, G., Nov 2023, In: PLoS biology. 21, 11, e3002367.

Research output: Contribution to journal › Article › peer-review

Open Access

Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis

Muta, Y., Linares, J. F., Martinez-Ordoñez, A., Duran, A., Cid-Diaz, T., Kinoshita, H., Zhang, X., Han, Q., Nakanishi, Y., Nakanishi, N., Cordes, T., Arora, G. K., Ruiz-Martinez, M., Reina-Campos, M., Kasashima, H., Yashiro, M., Maeda, K., Albaladejo-Gonzalez, A., Torres-Moreno, D., García-Solano, J., & 6 othersConesa-Zamora, P., Inghirami, G., Metallo, C. M., Osborne, T. F., Diaz-Meco, M. T. & Moscat, J., Dec 2023, In: Nature communications. 14, 1, 8075.

Research output: Contribution to journal › Article › peer-review

Open Access

Identification of the novel role of sterol regulatory element binding proteins (SREBPs) in mechanotransduction and intraocular pressure regulation

Wang, T., Soundararajan, A., Rabinowitz, J., Jaiswal, A., Osborne, T. & Pattabiraman, P. P., Nov 2023, In: FASEB Journal. 37, 11, e23248.

Research output: Contribution to journal › Article › peer-review

Open Access

SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization

Lee, J. H., Lee, S. H., Lee, E. H., Cho, J. Y., Song, D. K., Lee, Y. J., Kwon, T. K., Oh, B. C., Cho, K. W., Osborne, T. F., Jeon, T. I. & Im, S. S., Mar 2023, In: Journal of Advanced Research. 45, p. 1-13 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

SREBP signaling is essential for effective B cell responses

Luo, W., Adamska, J. Z., Li, C., Verma, R., Liu, Q., Hagan, T., Wimmers, F., Gupta, S., Feng, Y., Jiang, W., Zhou, J., Valore, E., Wang, Y., Trisal, M., Subramaniam, S., Osborne, T. F. & Pulendran, B., Feb 2023, In: Nature Immunology. 24, 2, p. 337-348 12 p.

Research output: Contribution to journal › Article › peer-review

2022

Epigenetic and environmental regulation of adipocyte function

Matsumura, Y., Osborne, T. F. & Sakai, J., Jul 1 2022, In: Journal of biochemistry. 172, 1, p. 9-16 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Lipid balance must be just right to prevent development of severe liver damage

Osborne, T. F. & Espenshade, P. J., Jun 1 2022, In: Journal of Clinical Investigation. 132, 11, e160326.

Research output: Contribution to journal › Review article › peer-review

Open Access

MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis

Takahashi, H., Yang, G., Yoneshiro, T., Abe, Y., Ito, R., Yang, C., Nakazono, J., Okamoto-Katsuyama, M., Uchida, A., Arai, M., Jin, H., Choi, H., Tumenjargal, M., Xie, S., Zhang, J., Sagae, H., Zhao, Y., Yamaguchi, R., Nomura, Y., Shimizu, Y., & 14 othersYamada, K., Yasuda, S., Kimura, H., Tanaka, T., Wada, Y., Kodama, T., Aburatani, H., Zhu, M. S., Inagaki, T., Osborne, T. F., Kawamura, T., Ishihama, Y., Matsumura, Y. & Sakai, J., Dec 2022, In: Nature communications. 13, 1, 5715.

Research output: Contribution to journal › Article › peer-review

Open Access

Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus

Baek, Y. B., Kwon, H. J., Sharif, M., Lim, J., Lee, I. C., Ryu, Y. B., Lee, J. I., Kim, J. S., Lee, Y. S., Kim, D. H., Park, S. I., Kim, D. K., Kim, J. S., Choy, H. E., Lee, S., Choi, H. S., Osborne, T. F., Jeon, T. I. & Cho, K. O., Dec 2022, In: Signal Transduction and Targeted Therapy. 7, 1, 367.

Research output: Contribution to journal › Article › peer-review

Open Access

Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women

Divoux, A., Erdos, E., Whytock, K., Osborne, T. F. & Smith, S. R., Mar 1 2022, In: Cells. 11, 5, 848.

Research output: Contribution to journal › Article › peer-review

Open Access

Unique role for lncRNA HOTAIR in defining depot-specific gene expression patterns in human adipose-derived stem cells

Erdos, E., Divoux, A., Sandor, K., Halasz, L., Smith, S. R. & Osborne, T. F., May 1 2022, In: Genes and Development. 36, 9-10, p. 566-581 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Deficiency of histone lysine methyltransferase SETDB2 in hematopoietic cells promotes vascular inflammation and accelerates atherosclerosis

Zhang, X., Sun, J., Canfrán-Duque, A., Aryal, B., Tellides, G., Chang, Y. J., Suárez, Y., Osborne, T. F. & Fernández-Hernando, C., Jun 22 2021, In: JCI Insight. 6, 12, e147984.

Research output: Contribution to journal › Article › peer-review

Open Access

Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum

Esquejo, R. M., Roqueta-Rivera, M., Shao, W., Phelan, P. E., Seneviratne, U., am Ende, C. W., Hershberger, P. M., Machamer, C. E., Espenshade, P. J. & Osborne, T. F., Feb 18 2021, In: Cell Chemical Biology. 28, 2, p. 169-179.e7

Research output: Contribution to journal › Article › peer-review

Open Access

DNA Methylation as a Marker of Body Shape in Premenopausal Women

Divoux, A., Eroshkin, A., Erdos, E., Sandor, K., Osborne, T. F. & Smith, S. R., Jul 29 2021, In: Frontiers in Genetics. 12, 709342.

Research output: Contribution to journal › Article › peer-review

Open Access

Spatiotemporal dynamics of SETD5-containing NCoR–HDAC3 complex determines enhancer activation for adipogenesis

Matsumura, Y., Ito, R., Yajima, A., Yamaguchi, R., Tanaka, T., Kawamura, T., Magoori, K., Abe, Y., Uchida, A., Yoneshiro, T., Hirakawa, H., Zhang, J., Arai, M., Yang, C., Yang, G., Takahashi, H., Fujihashi, H., Nakaki, R., Yamamoto, S., Ota, S., & 10 othersTsutsumi, S., Inoue, S. I., Kimura, H., Wada, Y., Kodama, T., Inagaki, T., Osborne, T. F., Aburatani, H., Node, K. & Sakai, J., Dec 2021, In: Nature communications. 12, 1, 7045.

Research output: Contribution to journal › Article › peer-review

Open Access

SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice

Nguyen, T. T. P., Kim, D. Y., Lee, Y. G., Lee, Y. S., Truong, X. T., Lee, J. H., Song, D. K., Kwon, T. K., Park, S. H., Jung, C. H., Moon, C., Osborne, T. F., Im, S. S. & Jeon, T. I., Sep 16 2021, In: Molecular cell. 81, 18, p. 3820-3832.e7

Research output: Contribution to journal › Article › peer-review

Open Access

Ubiquitination-dependent and -independent repression of target genes by SETDB1 reveal a context-dependent role for its methyltransferase activity during adipogenesis

Zhang, J., Matsumura, Y., Kano, Y., Yoshida, A., Kawamura, T., Hirakawa, H., Inagaki, T., Tanaka, T., Kimura, H., Yanagi, S., Fukami, K., Doi, T., Osborne, T. F., Kodama, T., Aburatani, H. & Sakai, J., Jul 2021, In: Genes to Cells. 26, 7, p. 513-529 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans

Che, L., Chi, W., Qiao, Y., Zhang, J., Song, X., Liu, Y., Li, L., Jia, J., Pilo, M. G., Wang, J., Cigliano, A., Ma, Z., Kuang, W., Tang, Z., Zhang, Z., Shui, G., Ribback, S., Dombrowski, F., Evert, M., Pascale, R. M., & 6 othersCossu, C., Pes, G. M., Osborne, T. F., Calvisi, D. F., Chen, X. & Chen, L., Jan 1 2020, In: Gut. 69, 1, p. 177-186 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Correction: Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue (Experimental & Molecular Medicine, (2020), 52, 2, (238-252), 10.1038/s12276-020-0379-z)

Lee, J. H., Go, Y., Kim, D. Y., Lee, S. H., Kim, O. H., Jeon, Y. H., Kwon, T. K., Bae, J. H., Song, D. K., Rhyu, I. J., Lee, I. K., Shong, M., Oh, B. C., Petucci, C., Park, J. W., Osborne, T. F. & Im, S. S., Jun 1 2020, In: Experimental and Molecular Medicine. 52, 6, p. 988 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Fat Distribution in Women Is Associated with Depot-Specific Transcriptomic Signatures and Chromatin Structure

Divoux, A., Sandor, K., Bojcsuk, D., Yi, F., Hopf, M. E., Smith, J. S., Balint, B. L., Osborne, T. F. & Smith, S. R., May 15 2020, In: Journal of the Endocrine Society. 4, 6, bvaa042.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Inflammation triggers liver X receptor-dependent lipogenesis

Liebergall, S. R., Angdisen, J., Chan, S. H., Chang, Y. J., Osborne, T. F., Koeppel, A. F., Turner, S. D. & Schulman, I. G., Jan 1 2020, In: Molecular and cellular biology. 40, 2, e00364-19.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue

Lee, J. H., Go, Y., Kim, D. Y., Lee, S. H., Kim, O. H., Jeon, Y. H., Kwon, T. K., Bae, J. H., Song, D. K., Rhyu, I. J., Lee, I. K., Shong, M., Oh, B. C., Petucci, C., Park, J. W., Osborne, T. F. & Im, S. S., Feb 1 2020, In: Experimental and Molecular Medicine. 52, 2, p. 238-252 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2019

Estrogen-related receptor γ controls sterol regulatory element-binding protein-1c expression and alcoholic fatty liver

Kim, D. K., Kim, Y. H., Lee, J. H., Jung, Y. S., Kim, J., Feng, R., Jeon, T. I., Lee, I. K., Cho, S. J., Im, S. S., Dooley, S., Osborne, T. F., Lee, C. H. & Choi, H. S., Dec 2019, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 12, 158521.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

2018

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

Esquejo, R. M., Salatto, C. T., Delmore, J., Albuquerque, B., Reyes, A., Shi, Y., Moccia, R., Cokorinos, E., Peloquin, M., Monetti, M., Barricklow, J., Bollinger, E., Smith, B. K., Day, E. A., Nguyen, C., Geoghegan, K. F., Kreeger, J. M., Opsahl, A., Ward, J., Kalgutkar, A. S., & 8 othersTess, D., Butler, L., Shirai, N., Osborne, T. F., Steinberg, G. R., Birnbaum, M. J., Cameron, K. O. & Miller, R. A., May 2018, In: EBioMedicine. 31, p. 122-132 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

Differential open chromatin profile and transcriptomic signature define depot-specific human subcutaneous preadipocytes: Primary outcomes

Divoux, A., Sandor, K., Bojcsuk, D., Talukder, A., Li, X., Balint, B. L., Osborne, T. F. & Smith, S. R., Nov 26 2018, In: Clinical Epigenetics. 10, 1, 148.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch

Abe, Y., Fujiwara, Y., Takahashi, H., Matsumura, Y., Sawada, T., Jiang, S., Nakaki, R., Uchida, A., Nagao, N., Naito, M., Kajimura, S., Kimura, H., Osborne, T. F., Aburatani, H., Kodama, T., Inagaki, T. & Sakai, J., Dec 1 2018, In: Nature communications. 9, 1, 1566.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance

Costford, S. R., Brouwers, B., Hopf, M. E., Sparks, L. M., Dispagna, M., Gomes, A. P., Cornnell, H. H., Petucci, C., Phelan, P., Xie, H., Yi, F., Walter, G. A., Osborne, T. F., Sinclair, D. A., Mynatt, R. L., Ayala, J. E., Gardell, S. J. & Smith, S. R., Jan 2018, In: Molecular Metabolism. 7, p. 1-11 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

SREBP-1a–stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1

Lee, J. H., Phelan, P., Shin, M., Oh, B. C., Han, X., Im, S. S. & Osborne, T. F., Dec 26 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 52, p. E12228-E12234

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways

Smith, K., Karimian Azari, E., LaMoia, T. E., Hussain, T., Vargova, V., Karolyi, K., Veldhuis, P. P., Arnoletti, J. P., de la Fuente, S. G., Pratley, R. E., Osborne, T. F. & Kyriazis, G. A., Nov 2018, In: Molecular Metabolism. 17, p. 98-111 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2017

Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis

Key, C. C. C., Liu, M., Kurtz, C. L., Chung, S., Boudyguina, E., Dinh, T. A., Bashore, A., Phelan, P. E., Freedman, B. I., Osborne, T. F., Zhu, X., Ma, L., Sethupathy, P., Biddinger, S. B. & Parks, J. S., Jun 6 2017, In: Cell Reports. 19, 10, p. 2116-2129 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: A randomized crossover interventional study

Azari, E. K., Smith, K. R., Yi, F., Osborne, T. F., Bizzotto, R., Mari, A., Pratley, R. E. & Kyriazis, G. A., Apr 1 2017, In: American Journal of Clinical Nutrition. 105, 4, p. 1001-1009 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2016

miRNA and cholesterol homeostasis

Jeon, T. I. & Osborne, T. F., Dec 1 2016, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1861, 12, p. 2041-2046 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

18 Scopus citations

SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation

Roqueta-Rivera, M., Esquejo, R. M., Phelan, P. E., Sandor, K., Daniel, B., Foufelle, F., Ding, J., Li, X., Khorasanizadeh, S. & Osborne, T. F., Sep 13 2016, In: Cell Metabolism. 24, 3, p. 474-484 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy

Kim, K. Y., Jang, H. J., Yang, Y. R., Park, K. I., Seo, J. K., Shin, I. W., Jeon, T. I., Ahn, S. C., Suh, P. G., Osborne, T. F. & Seo, Y. K., Oct 21 2016, In: Scientific reports. 6, 35732.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression

Vergnes, L., Chin, R. G., De Vallim, T. A., Fong, L. G., Osborne, T. F., Young, S. G. & Reue, K., Mar 2016, In: Journal of Lipid Research. 57, 3, p. 410-421 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

2015

H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation

Matsumura, Y., Nakaki, R., Inagaki, T., Yoshida, A., Kano, Y., Kimura, H., Tanaka, T., Tsutsumi, S., Nakao, M., Doi, T., Fukami, K., Osborne, T. F., Kodama, T., Aburatani, H. & Sakai, J., Nov 19 2015, In: Molecular cell. 60, 4, p. 584-596 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

103 Scopus citations

JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis

Abe, Y., Rozqie, R., Matsumura, Y., Kawamura, T., Nakaki, R., Tsurutani, Y., Tanimura-Inagaki, K., Shiono, A., Magoori, K., Nakamura, K., Ogi, S., Kajimura, S., Kimura, H., Tanaka, T., Fukami, K., Osborne, T. F., Kodama, T., Aburatani, H., Inagaki, T. & Sakai, J., May 7 2015, In: Nature communications. 6, 7052.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis

Inagaki, T., Iwasaki, S., Matsumura, Y., Kawamura, T., Tanaka, T., Abe, Y., Yamasaki, A., Tsurutani, Y., Yoshida, A., Chikaoka, Y., Nakamura, K., Magoori, K., Nakaki, R., Osborne, T. F., Fukami, K., Aburatani, H., Kodama, T. & Sakai, J., Feb 13 2015, In: Journal of Biological Chemistry. 290, 7, p. 4163-4177 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

2014

Lipid-cell cycle nexus: SREBP regulates microRNAs targeting Fbxw7

Esquejo, R. M., Jeon, T. I. & Osborne, T. F., Feb 1 2014, In: Cell Cycle. 13, 3, p. 339-340 2 p.

Research output: Contribution to journal › Editorial › peer-review

Open Access

8 Scopus citations

Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism

Masri, S., Rigor, P., Cervantes, M., Ceglia, N., Sebastian, C., Xiao, C., Roqueta-Rivera, M., Deng, C., Osborne, T. F., Mostoslavsky, R., Baldi, P. & Sassone-Corsi, P., Jul 31 2014, In: Cell. 158, 3, p. 659-672 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

162 Scopus citations

Response to gerlic et al.

Im, S. S., Young, S. G., Raffatellu, M. & Osborne, T. F., Mar 4 2014, In: Cell Metabolism. 19, 3, p. 346-347 2 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

2013

An SREBP-responsive microRNA operon contributes to a regulatory loop for intracellular lipid homeostasis

Jeon, T. I., Esquejo, R. M., Roqueta-Rivera, M., Phelan, P. E., Moon, Y. A., Govindarajan, S. S., Esau, C. C. & Osborne, T. F., Jul 2 2013, In: Cell Metabolism. 18, 1, p. 51-61 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

78 Scopus citations

Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

Kidani, Y., Elsaesser, H., Hock, M. B., Vergnes, L., Williams, K. J., Argus, J. P., Marbois, B. N., Komisopoulou, E., Wilson, E. B., Osborne, T. F., Graeber, T. G., Reue, K., Brooks, D. G. & Bensinger, S. J., May 2013, In: Nature Immunology. 14, 5, p. 489-499 11 p.

Research output: Contribution to journal › Article › peer-review

222 Scopus citations

2012

Genome-wide analysis of FoxO1 binding in hepatic chromatin: Potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis

Shin, D. J., Joshi, P., Hong, S. H., Mosure, K., Shin, D. G. & Osborne, T. F., Dec 2012, In: Nucleic acids research. 40, 22, p. 11499-11509 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR

Chong, H. K., Biesinger, J., Seo, Y. K., Xie, X. & Osborne, T. F., Feb 1 2012, In: BMC genomics. 13, 1, 51.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J. U., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J., & 1,249 othersAleo, M. F. R., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. H. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W. L., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H. I., Cho, D. H., Choi, A. M. K., Choi, D. S., Choi, K. S. O., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. 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Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

Freed-Pastor, W. A., Mizuno, H., Zhao, X., Langerød, A., Moon, S. H., Rodriguez-Barrueco, R., Barsotti, A., Chicas, A., Li, W., Polotskaia, A., Bissell, M. J., Osborne, T. F., Tian, B., Lowe, S. W., Silva, J. M., Børresen-Dale, A. L., Levine, A. J., Bargonetti, J. & Prives, C., Jan 20 2012, In: Cell. 148, 1-2, p. 244-258 15 p.

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