Timothy Osborne


1981 …2020

Research output per year

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Research Output

Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue

Lee, J. H., Go, Y., Kim, D. Y., Lee, S. H., Kim, O. H., Jeon, Y. H., Kwon, T. K., Bae, J. H., Song, D. K., Rhyu, I. J., Lee, I. K., Shong, M., Oh, B. C., Petucci, C., Park, J. W., Osborne, T. F. & Im, S. S., Jan 1 2020, (Accepted/In press) In : Experimental and Molecular Medicine.

Research output: Contribution to journalArticle

Open Access
  • Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans

    Che, L., Chi, W., Qiao, Y., Zhang, J., Song, X., Liu, Y., Li, L., Jia, J., Pilo, M. G., Wang, J., Cigliano, A., Ma, Z., Kuang, W., Tang, Z., Zhang, Z., Shui, G., Ribback, S., Dombrowski, F., Evert, M., Pascale, R. M. & 6 others, Cossu, C., Pes, G. M., Osborne, T., Calvisi, D. F., Chen, X. & Chen, L., Jan 1 2019, In : Gut.

    Research output: Contribution to journalArticle

    Open Access
  • Estrogen-related receptor γ controls sterol regulatory element-binding protein-1c expression and alcoholic fatty liver

    Kim, D. K., Kim, Y. H., Lee, J. H., Jung, Y. S., Kim, J., Feng, R., Jeon, T. I., Lee, I. K., Cho, S. J., Im, S. S., Dooley, S., Osborne, T., Lee, C. H. & Choi, H. S., Dec 1 2019, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 12, 158521.

    Research output: Contribution to journalArticle

  • Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

    Esquejo, R. M., Salatto, C. T., Delmore, J., Albuquerque, B., Reyes, A., Shi, Y., Moccia, R., Cokorinos, E., Peloquin, M., Monetti, M., Barricklow, J., Bollinger, E., Smith, B. K., Day, E. A., Nguyen, C., Geoghegan, K. F., Kreeger, J. M., Opsahl, A., Ward, J., Kalgutkar, A. S. & 8 others, Tess, D., Butler, L., Shirai, N., Osborne, T., Steinberg, G. R., Birnbaum, M. J., Cameron, K. O. & Miller, R. A., May 1 2018, In : EBioMedicine. 31, p. 122-132 11 p.

    Research output: Contribution to journalArticle

  • Differential open chromatin profile and transcriptomic signature define depot-specific human subcutaneous preadipocytes: Primary outcomes

    Divoux, A., Sandor, K., Bojcsuk, D., Talukder, A., Li, X., Balint, B. L., Osborne, T. & Smith, S. R., Nov 26 2018, In : Clinical Epigenetics. 10, 1, 148.

    Research output: Contribution to journalArticle