1991 …2020

Research output per year

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Research Output

1991

Endotoxin-inducible cytotoxicity in liver cell cultures-I

Hartung, T. & Wendel, A., Aug 8 1991, In : Biochemical Pharmacology. 42, 5, p. 1129-1135 7 p.

Research output: Contribution to journalArticle

Solcoseryl prevents inflammatory and hypoxic but not toxic liver damage in rodents

Hartung, T., Leist, M., Tiegs, G., Baschong, W. & Wendel, A., Mar 1 1991, In : Inflammopharmacology. 1, 1, p. 49-60 12 p.

Research output: Contribution to journalArticle

1992

Endotoxin-inducible cytotoxicity in liver cell cultures-II. Demonstration of endotoxin-tolerance

Hartung, T. & Wendel, A., Jan 22 1992, In : Biochemical Pharmacology. 43, 2, p. 191-196 6 p.

Research output: Contribution to journalArticle

Granulocyte colony-stimulating factor treatment protects rodents against lipopolysaccharide-induced toxicity via suppression of systemic tumor necrosis factor-α

Gorgen, I., Hartung, T., Leist, M., Niehorster, M., Tiegs, G., Uhlig, S., Weitzel, F. & Wendel, A., Jan 1 1992, In : Journal of Immunology. 149, 3, p. 918-924 7 p.

Research output: Contribution to journalArticle

The role of leukotriene D4 in septic shock models

Hartung, T., Tiegs, G. & Wendel, A., Jan 1 1992, In : Eicosanoids. 5, SUPPL., p. S42-S44

Research output: Contribution to journalArticle

1994

LTD4 augments TNF release in vivo and in vitro

Sauer, A. & Hartung, T., Aug 1 1994, In : Agents and Actions. 41, 2 Supplement, p. C155-C156

Research output: Contribution to journalArticle

1995

Effect of granulocyte colony-stimulating factor treatment on ex vivo blood cytokine response in human volunteers

Hartung, T., Döcke, W. D., Gantner, F., Krieger, G., Sauer, A., Stevens, P., Volk, H. D. & Wendel, A., May 1 1995, In : Blood. 85, 9, p. 2482-2489 8 p.

Research output: Contribution to journalArticle

G-CSF - an anti-inflammatory cytokine

Hartung, T., Volk, H. D. & Wendel, A., Jun 1995, In : Journal of Endotoxin Research. 2, 3, p. 195-201 7 p.

Research output: Contribution to journalArticle

1996

Control of fecal peritoneal infection in mice by colony-stimulating factors

Barsig, J., Bundschuh, D. S., Hartung, T., Bauhofer, A., Sauer, A. & Wendel, A., Jan 1 1996, In : Journal of Infectious Diseases. 174, 4, p. 790-799 10 p.

Research output: Contribution to journalArticle

Open Access

Detection of pyrogens using human whole blood

Hartung, T. & Wendel, A., Dec 1 1996, In : In Vitro and Molecular Toxicology: Journal of Basic and Applied Research. 9, 4, p. 353-359 7 p.

Research output: Contribution to journalArticle

Endotoxin-inducible granulocyte-mediated hepatocytotoxicity requires adhesion and serine protease release

Sauer, A., Hartung, T., Aigner, J. & Wendel, A., Nov 1996, In : Journal of Leukocyte Biology. 60, 5, p. 633-643 11 p.

Research output: Contribution to journalArticle

Testing of immunomodulatory properties in vitro.

Hartung, T., Sauer, A. & Wendel, A., 1996, In : Developments in biological standardization. 86, p. 85-96 12 p.

Research output: Contribution to journalArticle

1997

Cancer-related thromboembolic disease in patients with solid tumours: A retrospective analysis

Harrington, K. J., Bateman, A. R., Syrigos, K. N., Rintoul, R., Bhidayasiri, R., McCormack, M. & Thomas, H., Jul 1 1997, In : Annals of Oncology. 8, 7, p. 669-673 5 p.

Research output: Contribution to journalArticle

Filgrastim (r-metHuG-CSF) doubled CD4 counts in normal volunteers and restored in vitro IL-2 release in HIV patient blood

Hartung, T., Pitrak, D., Docke, W., Shatzen, E., Verral, S., Stevens, P. & Wendel, A., Dec 1 1997, In : Clinical Infectious Diseases. 25, 2, 1 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor and IFN-γ Restore the Systemic TNF-γ Response to Endotoxin in Lipopolysaccharide-Desensitized Mice

Bundschuh, D. S., Barsig, J., Hartung, T., Randow, F., Döcke, W. D., Volk, H. D. & Wendel, A., Mar 15 1997, In : Journal of Immunology. 158, 6, p. 2862-2871 10 p.

Research output: Contribution to journalArticle

Immunomodulatory action of G-CSF in a rat model of endotoxin-induced liver injury: An intravital microscopic analysis of Kupffer cell and leukocyte response

Vollmar, B., Messner, S., Wanner, G. A., Hartung, T. & Menger, M. D., Dec 1997, In : Journal of Leukocyte Biology. 62, 6, p. 710-718 9 p.

Research output: Contribution to journalArticle

Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis

Keel, M., Ungethüm, U., Steckholzer, U., Niederer, E., Hartung, T., Trentz, O. & Ertel, W., Nov 15 1997, In : Blood. 90, 9, p. 3356-3363 8 p.

Research output: Contribution to journalArticle

In Vitro Prevention and Reversal of Lipopolysaccharide Desensitization by IFN-γ, IL-12, and Granulocyte-Macrophage Colony-Stimulating Factor

Randow, F., Döcke, W. D., Bundschuh, D. S., Hartung, T., Wendel, A. & Volk, H. D., Mar 15 1997, In : Journal of Immunology. 158, 6, p. 2911-2918 8 p.

Research output: Contribution to journalArticle

Overactivation of the immune system by translocated bacteria and bacterial products

Hartung, T., Sauer, A., Hermann, C., Brockhaus, F. & Wendel, A., Jan 1 1997, In : Scandinavian Journal of Gastroenterology, Supplement. 32, 222, p. 98-99 2 p.

Research output: Contribution to journalShort survey

1998

Anti-inflammatory effects of granulocyte colony-stimulating factor

Hartung, T., Jan 1 1998, In : Current opinion in hematology. 5, 3, p. 221-225 5 p.

Research output: Contribution to journalReview article

Different efficacy of soluble CD14 treatment in high- and low-dose LPS models

Stelter, F., Witt, S., Fürll, B., Jack, R. S., Hartung, T. & Schütt, C., Apr 27 1998, In : European Journal of Clinical Investigation. 28, 3, p. 205-213 9 p.

Research output: Contribution to journalArticle

Filgrastim restores interleukin-2 production in blood from patients with advanced human immunodeficiency virus infection

Hartung, T., Pitrak, D. L., Foote, M., Shatzen, E. M., Verral, S. C. & Wendel, A., Jan 1 1998, In : Journal of Infectious Diseases. 178, 3, p. 686-692 7 p.

Research output: Contribution to journalArticle

Open Access

G-CSF and GM-CSF in the treatment of sepsis and inflammation

Wendel, A., Hartung, T. & Bundschuh, D. S., Jan 1 1998, In : Clinical Chemistry and Laboratory Medicine. 36, 4, p. A32

Research output: Contribution to journalArticle

Keratinocyte growth factor protects murine hepatocytes from tumor necrosis factor-induced apoptosis in vivo and in vitro

Senaldi, G., Shaklee, C. L., Simon, B., Rowan, C. G., Lacey, D. L. & Hartung, T., Jun 20 1998, In : Hepatology. 27, 6, p. 1584-1591 8 p.

Research output: Contribution to journalArticle

Role of granulocyte colony stimulating factor in infection and inflammation

Hartung, T., Von Aulock, S. & Wendel, A., Nov 11 1998, In : Medical Microbiology and Immunology. 187, 2, p. 61-69 9 p.

Research output: Contribution to journalReview article

1999

Anti-inflammatory aspects of filgrastim and impact on IL-2 release

Hartung, T., Dec 17 1999, In : Journal of Hematotherapy and Stem Cell Research. 8, SUPPL. 1, p. S21-S22

Research output: Contribution to journalReview article

Detection of endotoxins and other pyrogens using human whole blood.

Fennrich, S., Fischer, M., Hartung, T., Lexa, P., Montag-Lessing, T., Sonntag, H. G., Weigandt, M. & Wendel, A., 1999, In : Developments in biological standardization. 101, p. 131-139 9 p.

Research output: Contribution to journalArticle

Effect of filgrastim treatment on inflammatory cytokines and lymphocyte functions

Hartung, T., Doecke, W. D., Bundschuh, D., Foote, M. A., Gantner, F., Hermann, C., Lenz, A., Milwee, S., Rich, B., Simon, B., Volk, H. D., Von Aulock, S. & Wendel, A., Nov 1 1999, In : Clinical pharmacology and therapeutics. 66, 4, p. 415-424 10 p.

Research output: Contribution to journalArticle

Erratum: Outcome prediction by traditional and new markers of inflammation in patients with sepsis (Clinical Chemistry and Laboratory Medicine (1999) 37 (363-368))

Oberhoffer, M., Vogelsang, H., Russwurm, S., Hartung, T. & Reinhart, K., Sep 1 1999, In : Clinical Chemistry and Laboratory Medicine. 37, 6, 1 p.

Research output: Contribution to journalComment/debate

Granulocyte colony-stimulating factor: Its potential role in infectious disease

Hartung, T., Dec 21 1999, In : AIDS, Supplement. 13, 2, p. S3-S9

Research output: Contribution to journalArticle

Granulocyte colony-stimulating factor inhibits neutrophil apoptois at the local site after severe head and thoracic injury

Ertel, W., Keel, M., Buergi, U., Hartung, T., Imhof, H. G. & Trentz, O., May 1 1999, In : Journal of Trauma - Injury, Infection and Critical Care. 46, 5, p. 784-793 10 p.

Research output: Contribution to journalArticle

Immunomodulation by colony-stimulating factors.

Hartung, T., 1999, In : Reviews of Physiology, Biochemistry and Pharmacology. 136, p. 1-164 164 p.

Research output: Contribution to journalReview article

Outcome prediction by traditional and new markers of inflammation in patients with sepsis

Oberhoffer, M., Vogelsang, H., Rußwurm, S., Hartung, T. & Reinhart, K., May 17 1999, In : Clinical Chemistry and Laboratory Medicine. 37, 3, p. 363-368 6 p.

Research output: Contribution to journalArticle

Structures in Bacillus subtilis are recognized by CD14 in a lipopolysaccharide binding protein-dependent reaction

Fan, X., Stelter, F., Menzel, R., Jack, R., Spreitzer, I., Hartung, T. & Schütt, C., Jun 1 1999, In : Infection and immunity. 67, 6, p. 2964-2968 5 p.

Research output: Contribution to journalArticle

Temporal sequence of pulmonary and systemic inflammatory responses to graded polymicrobial peritonitis in mice

Stamme, C., Bundschuh, D. S., Hartung, T., Gebert, U., Wollin, L., Nüsing, R., Wendel, A. & Uhlig, S., Nov 1 1999, In : Infection and immunity. 67, 11, p. 5642-5650 9 p.

Research output: Contribution to journalArticle

2000

A new mechanism for IL-5-dependent helminth control: Neutrophil accumulation and neutrophil-mediated worm encapsulation in murine filariasis are abolished in the absence of IL-5

Al-Qaoud, K. M., Pearlman, E., Hartung, T., Klukowski, J., Fleischer, B. & Hoerauf, A., Jan 1 2000, In : International Immunology. 12, 6, p. 899-908 10 p.

Research output: Contribution to journalArticle

Open Access

Binding of surfactant protein D to lipoteichoic acid

Van De Watering, J. K., Van Eijk, M., Spreitzer, I., Härtung, T., Van Golde, L. M. G. & Batenburg, J. J., Dec 1 2000, In : Applied Cardiopulmonary Pathophysiology. 9, 3, 1 p.

Research output: Contribution to journalArticle

Blood cytokine response of low-dose molgramostim (rhGM-CSF)-treated patients

Hartung, T., Von Aulock, S., Freitag, M., Höxtermann, S., Stücker, M., Hoffmann, K., Altmeyer, P., Kottke, A. & Wendel, A., Jan 1 2000, In : Cytokine. 12, 10, p. 1570-1574 5 p.

Research output: Contribution to journalArticle

cGMP-mediated inhibition of TNF-α production by the atrial natriuretic peptide in murine macrophages

Kiemer, A. K., Hartung, T. & Vollmar, A. M., Jul 1 2000, In : Journal of Immunology. 165, 1, p. 175-181 7 p.

Research output: Contribution to journalArticle

Chip, Chip, Hurra! Die Amerikaner feiern den Gen-Chip--feiern wir mit?

Translated title of the contribution: Hip, hip, hurrah! Americans celebrate Gen-Chip--are we celebrating too?Hartung, T., 2000, In : ALTEX : Alternativen zu Tierexperimenten. 17, 2, p. 101-102 2 p.

Research output: Contribution to journalArticle

Effects of neutralizing antibodies to TNF-alpha on pain-related behavior and nerve regeneration in mice with chronic constriction injury

Lindenlaub, T., Teuteberg, P., Hartung, T. & Sommer, C., Jun 2 2000, In : Brain research. 866, 1-2, p. 15-22 8 p.

Research output: Contribution to journalArticle

Human monocytes express functional receptors for granulocyte colony- stimulating factor that mediate suppression of monokines and interferon-γ

Boneberg, E. M., Hareng, L., Gantner, F., Wendel, A. & Hartung, T., Jan 1 2000, In : Blood. 95, 1, p. 270-276 7 p.

Research output: Contribution to journalArticle

Inflammatory and immunological parameters in children with haemolytic uremic syndrome (HUS) and gastroenteritis - Pathophysiological and diagnostic clues

Westerholt, S., Hartung, T., Tollens, M., Güstrau, A., Oberhoffer, M., Karch, H., Klare, B., Pfeffer, K., Emmrich, P. & Oberhoffer, R., Jun 2000, In : Cytokine. 12, 6, p. 822-827 6 p.

Research output: Contribution to journalArticle

Intermittent G-CSF (filgrastim) treatment cannot induce lymphocytosis in volunteers

Von Aulock, S., Boneberg, E. M. & Hartung, T., Aug 19 2000, In : Clinical pharmacology and therapeutics. 68, 1, 1 p.

Research output: Contribution to journalLetter

Role of TNF-α in high-dose antigen therapy in experimental autoimmune neuritis: Inhibition of TNF-α by neutralizing antibodies reduces T-cell apoptosis and prevents liver necrosis

Weishaupt, A., Gold, R., Hartung, T., Gaupp, S., Wendel, A., Brück, W. & Toyka, K. V., May 2000, In : Journal of neuropathology and experimental neurology. 59, 5, p. 368-376 9 p.

Research output: Contribution to journalArticle

Open Access
2001

Anti-TNF-neutralizing antibodies reduce pain-related behavior in two different mouse models of painful mononeuropathy

Sommer, C., Lindenlaub, T., Teuteberg, P., Schäfers, M., Hartung, T. & Toyka, K. V., Sep 14 2001, In : Brain research. 913, 1, p. 86-89 4 p.

Research output: Contribution to journalArticle

Beispiel eines neuen Einsatzbereichs des humanen Vollbluttests: Entwicklung eines Messverfahrens zur Abschätzung der gesundheitlichen Gefährdung durch luftgetragene mikrobielle Verunreinigungen.

Translated title of the contribution: A new application for the human whole blood test: development of an assay to assess the health risk of air-borne microbial contaminationsFennrich, S., Zucker, B. & Hartung, T., 2001, In : ALTEX : Alternativen zu Tierexperimenten. 18, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

Borrelia burgdorferi s.l., the infectious agent of Lyme borreliosis.

Diterich, I. & Hartung, T., 2001, In : Contributions to microbiology. 8, p. 72-89 18 p.

Research output: Contribution to journalReview article

Characteristics of surfactant protein A and D binding to lipoteichoic acid and peptidoglycan, 2 major cell wall components of gram-positive bacteria

Van de Wetering, J. K., Van Eijk, M., Van Golde, L. M. G., Hartung, T., Van Strijp, J. A. G. & Batenburg, J. J., Nov 1 2001, In : Journal of Infectious Diseases. 184, 9, p. 1143-1151 9 p.

Research output: Contribution to journalArticle

Dissociation of LPS-induced monocytic ex vivo production of granulocyte colony-stimulating factor (G-CSF) and TNF-α in patients with septic shock

Weiss, M., Fischer, G., Barth, E., Boneberg, E., Schneider, E. M., Georgieff, M. & Hartung, T., Jan 7 2001, In : Cytokine. 13, 1, p. 51-54 4 p.

Research output: Contribution to journalArticle