Research Output 1978 2016

  • 56 Article
  • 1 Conference contribution
2016

Electrical Nerve Stimulation Enhances Perilesional Branching after Nerve Grafting but Fails to Increase Regeneration Speed in a Murine Model

Witzel, C., Brushart, T. M., Koulaxouzidis, G. & Infanger, M. Jan 9 2016 (Accepted/In press) In : Journal of Reconstructive Microsurgery.

Research output: Research - peer-reviewArticle

Electric Stimulation
Axons
Regeneration
Fibrin Tissue Adhesive
Sciatic Nerve

NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone

Tomlinson, R. E., Li, Z., Zhang, Q., Goh, B. C., Li, Z., Thorek, D. L. J., Rajbhandari, L., Brushart, T. M., Minichiello, L., Zhou, F., Venkatesan, A. & Clemens, T. L. Sep 1 2016 In : Cell Reports. 16, 10, p. 2723-2735 13 p.

Research output: Research - peer-reviewArticle

Nerve Growth Factor
Osteogenesis
Bone and Bones
Bone
Nerve Growth Factors

The topographic specificity of muscle reinnervation predicts function

O'Daly, A., Rohde, C. & Brushart, T. M. Feb 1 2016 In : European Journal of Neuroscience. 43, 3, p. 443-450 8 p.

Research output: Research - peer-reviewArticle

Elbow
Muscles
Musculocutaneous Nerve
Motor Neurons
Radial Nerve
2014

A two-compartment organotypic model of mammalian peripheral nerve repair

Siddique, R., Vyas, A., Thakor, N. & Brushart, T. M. Jul 30 2014 In : Journal of Neuroscience Methods. 232, p. 84-92 9 p.

Research output: Research - peer-reviewArticle

Peripheral Nerves
Axons
Motor Neurons
Regeneration
Water

MRI of sports-related peripheral nerve injuries

Mitchell, C. H., Brushart, T. M., Ahlawat, S., Belzberg, A. J., Carrino, J. A. & Fayad, L. M. Nov 1 2014 In : American Journal of Roentgenology. 203, 5, p. 1075-1084 10 p.

Research output: Research - peer-reviewArticle

Peripheral Nerve Injuries
Sports
Soft Tissue Injuries
Athletes
Joints

Novel roles for osteopontin and clusterin in peripheral motor and sensory axon regeneration

Wright, M. C., Mi, R., Connor, E., Reed, N., Vyas, A., Alspalter, M., Coppola, G., Geschwind, D. H., Brushart, T. M. & Höke, A. 2014 In : Journal of Neuroscience. 34, 5, p. 1689-1700 12 p.

Research output: Research - peer-reviewArticle

Clusterin
Osteopontin
Axons
Regeneration
Efferent Pathways
2013

Adult motor axons preferentially reinnervate predegenerated muscle nerve

Abdullah, M., O'Daly, A., Vyas, A., Rohde, C. & Brushart, T. M. Nov 2013 In : Experimental Neurology. 249, p. 1-7 7 p.

Research output: Research - peer-reviewArticle

Axons
Transplants
Muscles
Motor Neurons
Skin

Schwann cell phenotype is regulated by axon modality and central-peripheral location, and persists in vitro

Brushart, T. M., Aspalter, M., Griffin, J. W., Redett, R., Hameed, H., Zhou, C., Wright, M., Vyas, A. & Höke, A. Sep 2013 In : Experimental Neurology. 247, p. 272-281 10 p.

Research output: Research - peer-reviewArticle

Spinal Nerve Roots
Schwann Cells
Axons
Phenotype
In Vitro Techniques
2011

Frontispiece

Brushart, T. M. Oct 2011 In : Journal of Hand Surgery: European Volume. 36, 8, p. 631 1 p.

Research output: Research - peer-reviewArticle

2010

An in vitro model of adult mammalian nerve repair

Vyas, A., Li, Z., Aspalter, M., Feiner, J., Hoke, A., Zhou, C., O'Daly, A., Abdullah, M., Rohde, C. & Brushart, T. M. May 2010 In : Experimental Neurology. 223, 1, p. 112-118 7 p.

Research output: Research - peer-reviewArticle

Regeneration
Transplants
In Vitro Techniques
Neurons
Motor Neurons
Peripheral Nervous System
Axons
Regeneration
Nerve Regeneration
Extremities

Rolipram-induced elevation of cAMP or chondroitinase ABC breakdown of inhibitory proteoglycans in the extracellular matrix promotes peripheral nerve regeneration

Udina, E., Ladak, A., Furey, M., Brushart, T., Tyreman, N. & Gordon, T. May 2010 In : Experimental Neurology. 223, 1, p. 143-152 10 p.

Research output: Research - peer-reviewArticle

Chondroitin ABC Lyase
Rolipram
Nerve Regeneration
Proteoglycans
Peripheral Nerves
2009

Accelerating axon growth to overcome limitations in functional recovery after peripheral nerve injury

Gordon, T., Chan, K. M., Sulaiman, O. A. R., Udina, E., Amirjani, N. & Brushart, T. M. 2009 In : Neurosurgery. 65, SUPPL. 4

Research output: Research - peer-reviewArticle

Rolipram
Peripheral Nerve Injuries
Nerve Regeneration
Peripheral Nerves
Cyclic AMP

Modification of Schwann cell gene expression by electroporation in vivo

Aspalter, M., Vyas, A., Feiner, J., Griffin, J., Brushart, T. & Redett, R. Jan 30 2009 In : Journal of Neuroscience Methods. 176, 2, p. 96-103 8 p.

Research output: Research - peer-reviewArticle

Electroporation
Schwann Cells
Gene Expression
Genes
Axons
2008

Augmenting nerve regeneration with electrical stimulation

Gordon, T., Brushart, T. M. & Chan, K. M. Dec 2008 In : Neurological Research. 30, 10, p. 1012-1022 11 p.

Research output: Research - peer-reviewArticle

Nerve Regeneration
Schwann Cells
Electric Stimulation
Atrophy
Axotomy
2007

Electrical stimulation promotes sensory neuron regeneration and growth-associated gene expression

Geremia, N. M., Gordon, T., Brushart, T. M., Al-Majed, A. A. & Verge, V. M. K. Jun 2007 In : Experimental Neurology. 205, 2, p. 347-359 13 p.

Research output: Research - peer-reviewArticle

Sensory Receptor Cells
Electric Stimulation
Regeneration
Gene Expression
Neurons
Peripheral Nerve Injuries
Electric Stimulation
Neurons
Axons
Schwann Cells
2006

BDNF/TrkB signaling regulates HNK-1 carbohydrate expression in regenerating motor nerves and promotes functional recovery after peripheral nerve repair

Eberhardt, K. A., Irintchev, A., Al-Majed, A. A., Simova, O., Brushart, T. M., Gordon, T. & Schachner, M. Apr 2006 In : Experimental Neurology. 198, 2, p. 500-510 11 p.

Research output: Research - peer-reviewArticle

Brain-Derived Neurotrophic Factor
Peripheral Nerves
Carbohydrates
Electric Stimulation
Femoral Nerve

Schwann cells express motor and sensory phenotypes that regulate axon regeneration

Höke, A., Redett, R., Hameed, H., Jari, R., Zhou, C., Li, Z. B., Griffin, J. W. & Brushart, T. M. Sep 20 2006 In : Journal of Neuroscience. 26, 38, p. 9646-9655 10 p.

Research output: Research - peer-reviewArticle

Schwann Cells
Axons
Regeneration
Phenotype
Skin
2005

Electrical stimulation restores the specificity of sensory axon regeneration

Brushart, T. M., Jari, R., Verge, V., Rohde, C. & Gordon, T. Jul 2005 In : Experimental Neurology. 194, 1, p. 221-229 9 p.

Research output: Research - peer-reviewArticle

Electric Stimulation
Axons
Regeneration
Muscles
Neurons

Pathway sampling by regenerating peripheral axons

Witzel, C., Rohde, C. & Brushart, T. M. May 9 2005 In : Journal of Comparative Neurology. 485, 3, p. 183-190 8 p.

Research output: Research - peer-reviewArticle

Axons
Wallerian Degeneration
Growth Cones
Schwann Cells
Sciatic Nerve

Peripheral pathways regulate motoneuron collateral dynamics

Redett, R., Jari, R., Crawford, T., Chen, Y. G., Rohde, C. & Brushart, T. M. Oct 12 2005 In : Journal of Neuroscience. 25, 41, p. 9406-9412 7 p.

Research output: Research - peer-reviewArticle

Motor Neurons
Muscles
Skin
Axons
Spinal Ganglia
2003

Antibodies to myelin-associated glycoprotein accelerate preferential motor reinnervation

Mears, S., Schachner, M. & Brushart, T. M. Jun 2003 In : Journal of the Peripheral Nervous System. 8, 2, p. 91-99 9 p.

Research output: Research - peer-reviewArticle

Myelin-Associated Glycoprotein
Antibodies
Regeneration
Muscles
Therapeutics
2002

Electrical stimulation promotes motoneuron regeneration without increasing its speed or conditioning the neuron

Brushart, T. M., Hoffman, P. N., Royall, R. M., Murinson, B. B., Witzel, C. & Gordon, T. Aug 1 2002 In : Journal of Neuroscience. 22, 15, p. 6631-6638 8 p.

Research output: Research - peer-reviewArticle

Motor Neurons
Electric Stimulation
Regeneration
Neurons
Femoral Nerve
2001

Effects of pathway and neuronal aging on the specificity of motor axon regeneration

Le, T. B., Aszmann, O., Chen, Y. G., Royall, R. M. & Brushart, T. M. 2001 In : Experimental Neurology. 167, 1, p. 126-132 7 p.

Research output: Research - peer-reviewArticle

Axons
Regeneration
Transplants
Motor Neurons
Muscles
2000

Brief electrical stimulation promotes the speed and accuracy of motor axonal regeneration

Al-Majed, A. A., Neumann, C. M., Brushart, T. M. & Gordon, T. Apr 1 2000 In : Journal of Neuroscience. 20, 7, p. 2602-2608 7 p.

Research output: Research - peer-reviewArticle

Electric Stimulation
Regeneration
Axons
Femoral Nerve
Muscles

Electrical stimulation accelerates and increases expression of BDNF and trkB mRNA in regenerating rat femoral motoneurons

Al-Majed, A. A., Brushart, T. M. & Gordon, T. 2000 In : European Journal of Neuroscience. 12, 12, p. 4381-4390 10 p.

Research output: Research - peer-reviewArticle

Brain-Derived Neurotrophic Factor
Motor Neurons
Thigh
Electric Stimulation
Messenger RNA
1999

The effects of free fat grafts on the stiffness of the rat sciatic nerve and perineural scar

Dumanian, G. A., McClinton, M. A. & Brushart, T. M. Jan 1999 In : Journal of Hand Surgery. 24, 1, p. 30-36 7 p.

Research output: Research - peer-reviewArticle

Sciatic Nerve
Cicatrix
Fats
Transplants
Weights and Measures
1998

Contributions of pathway and neuron to preferential motor reinnervation

Brushart, T. M., Gerber, J., Kessens, P., Chen, Y. G. & Royall, R. M. Nov 1 1998 In : Journal of Neuroscience. 18, 21, p. 8674-8681 8 p.

Research output: Research - peer-reviewArticle

Axons
Neurons
Muscles
Transplants
Skin

The effect of denervated muscle and schwann cells on axon collateral sprouting

Chen, Y. G. & Brushart, T. M. 1998 In : Journal of Hand Surgery. 23, 6, p. 1025-1033 9 p.

Research output: Research - peer-reviewArticle

Schwann Cells
Muscle Cells
Axons
Muscles
Peroneal Nerve
1997

Neurotization of the rat soleus muscle: A quantitative analysis of reinnervation

Payne S.H., J. & Brushart, T. M. 1997 In : Journal of Hand Surgery. 22, 4, p. 640-643 4 p.

Research output: Research - peer-reviewArticle

Nerve Transfer
Motor Endplate
Skeletal Muscle
Tibial Nerve
Neurobiology
1996

Reinnervation accuracy of the rat femoral nerve by motor and sensory neurons

Madison, R. D., Archibald, S. J. & Brushart, T. M. Sep 15 1996 In : Journal of Neuroscience. 16, 18, p. 5698-5703 6 p.

Research output: Research - peer-reviewArticle

Femoral Nerve
Motor Neurons
Sensory Receptor Cells
Regeneration
Muscles
1995

Dispersion of regenerating axons across enclosed neural gaps

Brushart, T. M., Mathur, V., Sood, R. & Koschorke, G. M. 1995 In : Journal of Hand Surgery. 20, 4, p. 557-564 8 p.

Research output: Research - peer-reviewArticle

Axons
Regeneration
Silicon
Sciatic Nerve
Primates
1994

Distal vacuolar myopathy in nephropathic cystinosis

Charnas, L. R., Luciano, C. A., Dalakas, M., Gilliatt, R. W., Bernardini, I., Ishak, K., Cwik, V. A., Fraker, D., Brushart, T. A. & Gahl, W. A. Feb 1994 In : Annals of Neurology. 35, 2, p. 181-188 8 p.

Research output: Research - peer-reviewArticle

Distal Myopathies
Cystinosis
Muscles
Vacuolar myopathy
Cystine

Peripheral nerve surgery today: Turning point or continuous development? (Part II): Neurotropism

Brushart, T. M., Zhao, Q., Dahlin, L. B., Kanje, L. B., Lundborg, G., Carlstedt, T., Hallin, R. G., Nilsson-Remahl, I., Samii, . N. V., Narakas, . N. V., Millesi, . N. V., Noa, . N. V., Brunelli, . N. V. & Bunge, . N. V. 1994 In : Journal of Reconstructive Microsurgery. 10, 2, p. 121-125 5 p.

Research output: Research - peer-reviewArticle

Peripheral Nerves
Axons
Organ Specificity
Nerve Regeneration

The L2/HNK-1 carbohydrate is preferentially expressed by previously motor axon-associated Schwann cells in reinnervated peripheral nerves

Martini, R., Schachner, M. & Brushart, T. M. 1994 In : Journal of Neuroscience. 14, 11 II, p. 7180-7191 12 p.

Research output: Research - peer-reviewArticle

Schwann Cells
Peripheral Nerves
Axons
Carbohydrates
Muscles
1993

Motor axons preferentially reinnervate motor pathways

Brushart, T. M. E. 1993 In : Journal of Neuroscience. 13, 6, p. 2730-2738 9 p.

Research output: Research - peer-reviewArticle

Efferent Pathways
Axons
Muscles
Femoral Nerve
Transplants

Prolonged survival of transected nerve fibres in C57BL/Ola mice is an intrinsic characteristic of the axon

Glass, J. D., Brushart, T. M., George, E. B. & Griffin, J. W. May 1993 In : Journal of Neurocytology. 22, 5, p. 311-321 11 p.

Research output: Research - peer-reviewArticle

Inbred C57BL Mouse
Nerve Fibers
Axons
Schwann Cells
Phenotype
1991

Central course of digital axons within the median nerve of Macaca mulatta

Brushart, T. M. E. 1991 In : Journal of Comparative Neurology. 311, 2, p. 197-209 13 p.

Research output: Research - peer-reviewArticle

Median Nerve
Macaca mulatta
Axons
Fingers
Thumb
1990

Preferential motor reinnervation: A sequential double-labeling study

Brushart, T. M. E. 1990 In : Restorative Neurology and Neuroscience. 1, 3-4, p. 281-287 7 p.

Research output: Research - peer-reviewArticle

Axons
Motor Neurons
Regeneration
Neurons
Femoral Nerve
1989

Somatotopy of digital nerve projections to the cuneate nucleus in the monkey

Culberson, J. L. & Brushart, T. M. 1989 In : Somatosensory & Motor Research. 6, 3, p. 319-330 12 p.

Research output: Research - peer-reviewArticle

Macaca
Haplorhini
Agglutinins
Thumb
Horseradish Peroxidase

Somatotopy of digital nerve projections to the dorsal horn in the monkey

Brown, P. B., Brushart, T. M. & Ritz, L. A. 1989 In : Somatosensory & Motor Research. 6, 3, p. 309-317 9 p.

Research output: Research - peer-reviewArticle

Haplorhini
Spinal Cord Dorsal Horn
Cats
Fingers
Skin
1988

Preferential reinnervation of motor nerves by regenerating motor axons

Brushart, T. M. E. 1988 In : Journal of Neuroscience. 8, 3, p. 1026-1031 6 p.

Research output: Research - peer-reviewArticle

Axons
Motor Neurons
Femoral Nerve
Schwann Cells
Sensory Receptor Cells
1987

Neurotropism and neurotrophism.

Brushart, T. M. Sep 1987 In : Journal of Hand Surgery. 12, 5 Pt 1, p. 808-809 2 p.

Research output: Research - peer-reviewArticle

Selective reinnervation of distal motor stumps by peripheral motor axons

Brushart, T. M. E. & Seiler IV, W. A. 1987 In : Experimental Neurology. 97, 2, p. 289-300 12 p.

Research output: Research - peer-reviewArticle

Axons
Motor Neurons
Reunion
Motor Endplate
Femoral Nerve
1985

Allograft bone for metacarpal reconstruction

Smith, R. J. & Brushart, T. M. 1985 In : Journal of Hand Surgery. 10, 3, p. 325-334 10 p.

Research output: Research - peer-reviewArticle

Metacarpal Bones
Allografts
Bone and Bones
Thumb
Tissue Donors

Nerve regeneration through biodegradable polyester tubes

Henry, E. W., Chiu, T. H., Nyilas, E., Brushart, T. M., Dikkes, P. & Sidman, R. L. 1985 In : Experimental Neurology. 90, 3, p. 652-676 25 p.

Research output: Research - peer-reviewArticle

Nerve Regeneration
Polyesters
Myelin Sheath
Sciatic Nerve
Regeneration
1983

Peripheral nerve repair with bioresorbable prosthesis

Nyilas, E., Chiu, T. H., Sidman, R. L., Henry, E. W., Brushart, T. M., Dikkes, P. & Madison, R. 1983 In : Transactions - American Society for Artificial Internal Organs. 29, 1, p. 307-313 7 p.

Research output: Research - peer-reviewArticle

Specificity of muscle reinnervation after epineurial and individual fascicular suture of the rat sciatic nerve

Brushart, T. M., Tarlow, E. C. & Mesulam, M. M. 1983 In : Journal of Hand Surgery. 8, 3, p. 248-253 6 p.

Research output: Research - peer-reviewArticle

Sciatic Nerve
Sutures
Muscles
Motor Neurons
Tibial Nerve