Theodore DeWeese

Professor

1991 …2020

Research output per year

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Research Output

Article

8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells

Parker, A. R., O'Meally, R. N., Oliver, D. H., Hua, L., Nelson, W. G., DeWeese, T. L. & Eshleman, J. R., Dec 15 2002, In : Cancer Research. 62, 24, p. 7230-7233 4 p.

Research output: Contribution to journalArticle

Absorbable hydrogel spacer use in men undergoing prostate cancer radiotherapy: 12 month toxicity and proctoscopy results of a prospective multicenter phase II trial

Uhl, M., Herfarth, K., Eble, M. J., Pinkawa, M., van Triest, B., Kalisvaart, R., Weber, D. C., Miralbell, R., Song, D. Y. & DeWeese, T. L., Apr 24 2014, In : Radiation Oncology. 9, 1, 96.

Research output: Contribution to journalArticle

ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models

Donawho, C. K., Luo, Y., Luo, Y., Penning, T. D., Bauch, J. L., Bouska, J. J., Bontcheva-Diaz, V. D., Cox, B. F., DeWeese, T. L., Dillehay, L. E., Ferguson, D. C., Ghoreishi-Haack, N. S., Grimm, D. R., Guan, R., Han, E. K., Holley-Shanks, R. R., Hristov, B., Idler, K. B., Jarvis, K., Johnson, E. F. & 17 others, Kleinberg, L. R., Klinghofer, V., Lasko, L. M., Liu, X., Marsh, K. C., McGonigal, T. P., Meulbroek, J. A., Olson, A. M., Palma, J. P., Rodriguez, L. E., Shi, Y., Stavropoulos, J. A., Tsurutani, A. C., Zhu, G. D., Rosenberg, S. H., Giranda, V. L. & Frost, D. J., May 1 2007, In : Clinical Cancer Research. 13, 9, p. 2728-2737 10 p.

Research output: Contribution to journalArticle

Accuracy of marketing claims by providers of stereotactic radiation therapy

Narang, A. K., Lam, E., Makary, M. A., DeWeese, T. L., Pawlik, T. M., Pronovost, P. J. & Herman, J. M., Jan 1 2013, In : Journal of oncology practice. 9, 1, p. 57-62 6 p.

Research output: Contribution to journalArticle

Acute and late radiotherapy toxicity in patients with inflammatory bowel disease

Song, D. Y., Lawrie, W. T., Abrams, R. A., Kafonek, D. R., Bayless, T. M., Welsh, J. S. & DeWeese, T. L., Oct 1 2001, In : International Journal of Radiation Oncology Biology Physics. 51, 2, p. 455-459 5 p.

Research output: Contribution to journalArticle

Adoption of an incident learning system in a regionally expanding academic radiation oncology department

Wright, J., Parekh, A., Rhieu, B. H., Miller, D., Opris, V., Souranis, A., Choflet, A., Viswanathan, A., DeWeese, T., McNutt, T. & Terezakis, S. A., Jul 1 2019, In : Reports of Practical Oncology and Radiotherapy. 24, 4, p. 338-343 6 p.

Research output: Contribution to journalArticle

A dose texture plot in a moving frame as a new planning tool for single-plane implants in HDR brachytherapy

Li, S., DeWeese, T., Lee, D. J., Kleinberg, L. & Wharam, M., Jan 1 2001, In : Medical physics. 28, 1, p. 97-103 7 p.

Research output: Contribution to journalArticle

A functional screen identifies miRNAs that inhibit DNA repair and sensitize prostate cancer cells to ionizing radiation

Hatano, K., Kumar, B., Zhang, Y., Coulter, J. B., Hedayati, M., Mears, B., Ni, X., Kudrolli, T. A., Chowdhury, W. H., Rodriguez, R., DeWeese, T. L. & Lupold, S. E., Mar 17 2015, In : Nucleic acids research. 43, 8, p. 4075-4086 12 p.

Research output: Contribution to journalArticle

Aids-related non-hodgkin's lymphoma: The outcome and efficacy of radiation therapy

Deweese, T. L., Hazuka, M. B., Hommel, D. J., Kinzie, J. J. & Daniel, W. E., Apr 1 1991, In : International journal of radiation oncology, biology, physics. 20, 4, p. 803-808 6 p.

Research output: Contribution to journalArticle

A multi-institutional clinical trial of rectal dose reduction via injected polyethylene-glycol hydrogel during intensity modulated radiation therapy for prostate cancer: Analysis of dosimetric outcomes

Song, D. Y., Herfarth, K. K., Uhl, M., Eble, M. J., Pinkawa, M., Van Triest, B., Kalisvaart, R., Weber, D. C., Miralbell, R., DeWeese, T. L. & Ford, E. C., Sep 1 2013, In : International Journal of Radiation Oncology Biology Physics. 87, 1, p. 81-87 7 p.

Research output: Contribution to journalArticle

A Multi-Institutional Matched-Control Analysis of Adjuvant and Salvage Postoperative Radiation Therapy for pT3-4N0 Prostate Cancer

Trabulsi, E. J., Valicenti, R. K., Hanlon, A. L., Pisansky, T. M., Sandler, H. M., Kuban, D. A., Catton, C. N., Michalski, J. M., Zelefsky, M. J., Kupelian, P. A., Lin, D. W., Anscher, M. S., Slawin, K. M., Roehrborn, C. G., Forman, J. D., Liauw, S. L., Kestin, L. L., DeWeese, T. L., Scardino, P. T., Stephenson, A. J. & 1 others, Pollack, A., Dec 1 2008, In : Urology. 72, 6, p. 1298-1302 5 p.

Research output: Contribution to journalArticle

Analysis of Spatial Dose-Volume Relationships and Decline in Sexual Function Following Permanent Brachytherapy for Prostate Cancer

Peng, L. C., Mian, O. Y., Lakshminarayanan, P., Huang, P., Bae, H. J., Robertson, S., Habtu, T., Narang, A., Agarwal, S., Greco, S., Tran, P., McNutt, T., DeWeese, T. L. & Song, D. Y., Jan 2020, In : Urology. 135, p. 111-116 6 p.

Research output: Contribution to journalArticle

Androgen deprivation followed by acute androgen stimulation selectively sensitizes AR-positive prostate cancer cells to ionizing radiation

Hedayati, M., Haffner, M. C., Coulter, J. B., Raval, R. R., Zhang, Y., Zhou, H., Mian, O., Knight, E. J., Razavi, N., Dalrymple, S., Isaacs, J. T., Santos, A., Hales, R., Nelson, W. G., Yegnasubramanian, S. & DeWeese, T., Jul 1 2016, In : Clinical Cancer Research. 22, 13, p. 3310-3319 10 p.

Research output: Contribution to journalArticle

Androgen withdrawal fails to induce detectable tissue hypoxia in the rat prostate

Regter, S., Hedayati, M., Zhang, Y., Zhou, H., Dalrymple, S., Koch, C. J., Isaacs, J. T. & Deweese, T. L., Jun 2014, In : Prostate. 74, 8, p. 805-810 6 p.

Research output: Contribution to journalArticle

An evaluation of departmental radiation oncology incident reports: Anticipating a national reporting system

Terezakis, S. A., Harris, K. M., Ford, E., Michalski, J., DeWeese, T., Santanam, L., Mutic, S. & Gay, H., Mar 15 2013, In : International Journal of Radiation Oncology Biology Physics. 85, 4, p. 919-923 5 p.

Research output: Contribution to journalArticle

An optimised spectrophotometric assay for convenient and accurate quantitation of intracellular iron from iron oxide nanoparticles

Hedayati, M., Abubaker-Sharif, B., Khattab, M., Razavi, A., Mohammed, I., Nejad, A., Wabler, M., Zhou, H., Mihalic, J., Gruettner, C., DeWeese, T. & Ivkov, R., Jul 27 2017, (Accepted/In press) In : International Journal of Hyperthermia. p. 1-9 9 p.

Research output: Contribution to journalArticle

A Novel Absorbable Radiopaque Hydrogel Spacer to Separate the Head of the Pancreas and Duodenum in Radiation Therapy for Pancreatic Cancer

Rao, A. D., Feng, Z., Shin, E., He, J., Waters, K. M., Coquia, S., DeJong, R., Rosati, L. M., Su, L., Li, D., Jackson, J., Clark, S., Schultz, J., Hutchings, D., Kim, S. H., Hruban, R. H., DeWeese, T., Wong, J., Narang, A., Herman, J. M. & 1 others, Ding, K., 2017, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

Anti-Tumor Effect of Combination Therapy with Intratumoral Controlled-Release Paclitaxel (PACLIMER®Microspheres) and Radiation

Lapidus, R. G., Dang, W., Rosen, D. M., Gady, A. M., Zabelinka, Y., O'Meally, R., DeWeese, T. L. & Denmeade, S. R., Feb 15 2004, In : Prostate. 58, 3, p. 291-298 8 p.

Research output: Contribution to journalArticle

A phase II randomized placebo-controlled double-blind study of salvage radiation therapy plus placebo versus SRT plus enzalutamide with high-risk PSA-recurrent prostate cancer after radical prostatectomy (SALV-ENZA)

Kapoor, R., Deek, M. P., McIntyre, R., Raman, N., Kummerlowe, M., Chen, I., Gaver, M., Wang, H., Denmeade, S., Lotan, T., Paller, C., Markowski, M., Carducci, M., Eisenberger, M., Beer, T. M., Song, D. Y., Deweese, T. L., Hearn, J. W., Greco, S., Deville, C. & 7 others, Desai, N. B., Heath, E. I., Liauw, S., Spratt, D. E., Hung, A. Y., Antonarakis, E. S. & Tran, P. T., Jun 13 2019, In : BMC cancer. 19, 1, 572.

Research output: Contribution to journalArticle

Open Access

A Phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy

DeWeese, T. L., van der Poel, H., Li, S., Mikhak, B., Drew, R., Goemann, M., Hamper, U., DeJong, R., Detorie, N., Rodriguez, R., Haulk, T., DeMarzo, A. M., Piantadosi, S., Yu, D. C., Chen, Y., Henderson, D. R., Carducci, M. A., Nelson, W. G. & Simons, J. W., Oct 15 2001, In : Cancer Research. 61, 20, p. 7464-7472 9 p.

Research output: Contribution to journalArticle

A real-time image-guided intraoperative high-dose-rate brachytherapy system

Li, S., Frassica, D., DeWeese, T., Lee, D. J., Geng, J. & Nag, S., Jan 1 2003, In : Brachytherapy. 2, 1, p. 5-16 12 p.

Research output: Contribution to journalArticle

Open Access

A streamlined failure mode and effects analysis

Ford, E. C., Smith, K., Terezakis, S., Croog, V., Gollamudi, S., Gage, I., Keck, J., Deweese, T. & Sibley, G., Jun 2014, In : Medical physics. 41, 6, 061709.

Research output: Contribution to journalArticle

Bicalutamide-activated oncolytic adenovirus for the adjuvant therapy of high-risk prostate cancer

Johnson, T. J., Höti, N., Liu, C., Chowdhury, W. H., Li, Y., Zhang, Y., Lupold, S. E., Deweese, T. & Rodriguez, R., Jul 1 2013, In : Cancer Gene Therapy. 20, 7, p. 394-402 9 p.

Research output: Contribution to journalArticle

Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases

Rudra, A., Hou, D., Zhang, Y., Coulter, J., Zhou, H., Deweese, T. L. & Greenberg, M. M., Nov 6 2015, In : Journal of Organic Chemistry. 80, 21, p. 10675-10685 11 p.

Research output: Contribution to journalArticle

Burnout in United States academic chairs of radiation oncology programs

Kusano, A. S., Thomas, C. R., Bonner, J. A., Deweese, T. L., Formenti, S. C., Hahn, S. M., Lawrence, T. S. & Mittal, B. B., Feb 1 2014, In : International Journal of Radiation Oncology Biology Physics. 88, 2, p. 363-368 6 p.

Research output: Contribution to journalArticle

Changes to physician processing times in response to clinic congestion and patient punctuality: A retrospective study

Chambers, C. G., Dada, M., Elnahal, S., Terezakis, S. A., DeWeese, T., Herman, J. & Williams, K. A., Oct 1 2016, In : BMJ Open. 6, 10, e011730.

Research output: Contribution to journalArticle

Chloroquine improves survival and hematopoietic recovery after lethal low-dose-rate radiation

Lim, Y., Hedayati, M., Merchant, A. A., Zhang, Y., Yu, H. H. M., Kastan, M. B., Matsui, W. & DeWeese, T. L., Nov 1 2012, In : International Journal of Radiation Oncology Biology Physics. 84, 3, p. 800-806 7 p.

Research output: Contribution to journalArticle

Clinical Outcomes for Patients With Gleason Score 10 Prostate Adenocarcinoma: Results From a Multi-institutional Consortium Study

Sandler, K. A., Cook, R. R., Ciezki, J. P., Ross, A. E., Pomerantz, M. M., Nguyen, P. L., Shaikh, T., Tran, P. T., Stock, R. G., Merrick, G. S., Demanes, D. J., Spratt, D. E., Abu-Isa, E. I., Wedde, T. B., Lilleby, W., Krauss, D. J., Shaw, G. K., Alam, R., Reddy, C. A., Song, D. Y. & 21 others, Klein, E. A., Stephenson, A. J., Tosoian, J. J., Hegde, J. V., Yoo, S. M., Fiano, R., D'Amico, A. V., Nickols, N. G., Aronson, W. J., Sadeghi, A., Greco, S. C., Deville, C., McNutt, T., DeWeese, T. L., Reiter, R. E., Said, J. W., Steinberg, M. L., Horwitz, E. M., Kupelian, P. A., King, C. R. & Kishan, A. U., Jul 15 2018, In : International Journal of Radiation Oncology Biology Physics. 101, 4, p. 883-888 6 p.

Research output: Contribution to journalArticle

Clinical results of a pilot study on stereovision-guided stereotactic radiotherapy and intensity modulated radiotherapy

Li, S., Kleinberg, L. R., Rigamonti, D., Wharam, M. D., Rashid, A., Jackson, J., Djajaputra, D., He, S., Creasey, T. & DeWeese, T. L., Dec 2010, In : Technology in Cancer Research and Treatment. 9, 6, p. 603-617 15 p.

Research output: Contribution to journalArticle

Combined treatment effects of radiation and immunotherapy: Studies in an autochthonous prostate cancer model

Wada, S., Harris, T. J., Tryggestad, E., Yoshimura, K., Zeng, J., Yen, H. R., Getnet, D., Grosso, J. F., Bruno, T. C., De Marzo, A. M., Netto, G. J., Pardoll, D. M., Deweese, T. L., Wong, J. & Drake, C. G., Nov 15 2013, In : International Journal of Radiation Oncology Biology Physics. 87, 4, p. 769-776 8 p.

Research output: Contribution to journalArticle

Comparison of biochemical recurrence-free survival between periprostatic and pelvic lymph node metastases of prostate cancer

González-Roibón, N., Han, J. S., Lee, S., Feng, Z., Arslankoz, S., Smith, N., Pierorazio, P. M., Humphreys, E., Deweese, T. L., Partin, A. W., Bivalacqua, T. J., Han, M., Trock, B. & Netto, G. J., Aug 1 2013, In : International journal of surgical pathology. 21, 4, p. 352-357 6 p.

Research output: Contribution to journalArticle

Continued Benefit to Rectal Separation for Prostate Radiation Therapy: Final Results of a Phase III Trial

Hamstra, D. A., Mariados, N., Sylvester, J., Shah, D., Karsh, L., Hudes, R., Beyer, D., Kurtzman, S., Bogart, J., Hsi, R. A., Kos, M., Ellis, R., Logsdon, M., Zimberg, S., Forsythe, K., Zhang, H., Soffen, E., Francke, P., Mantz, C., Rossi, P. & 7 others, DeWeese, T., Daignault-Newton, S., Fischer-Valuck, B. W., Chundury, A., Gay, H., Bosch, W. & Michalski, J., Apr 1 2017, In : International Journal of Radiation Oncology Biology Physics. 97, 5, p. 976-985 10 p.

Research output: Contribution to journalArticle

CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity

Chen, Y., DeWeese, T., Dilley, J., Zhang, Y., Li, Y., Ramesh, N., Lee, J., Pennathur-Das, R., Radzyminski, J., Wypych, J., Brignetti, D., Scott, S., Stephens, J., Karpf, D. B., Henderson, D. R. & Yu, D. C., Jul 15 2001, In : Cancer Research. 61, 14, p. 5453-5460 8 p.

Research output: Contribution to journalArticle

Defective Human MutY Phosphorylation Exists in Colorectal Cancer Cell Lines with Wild-type MutY Alleles

Parker, A. R., O'Meally, R. N., Sahin, F., Su, G. H., Racke, F. K., Nelson, W. G., DeWeese, T. L. & Eshleman, J. R., Nov 28 2003, In : Journal of Biological Chemistry. 278, 48, p. 47937-47945 9 p.

Research output: Contribution to journalArticle

Design and construction of a Maxwell-type induction coil for magnetic nanoparticle hyperthermia

Attaluri, A., Jackowski, J., Sharma, A., Kandala, S. K., Nemkov, V., Yakey, C., DeWeese, T. L., Kumar, A., Goldstein, R. C. & Ivkov, R., Jan 1 2020, In : International Journal of Hyperthermia. 37, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

Open Access

Development and screening of a series of antibody-conjugated and silica-coated iron oxide nanoparticles for targeting the prostate-specific membrane antigen

Mukherjee, A., Darlington, T., Baldwin, R., Holz, C., Olson, S., Kulkarni, P., Deweese, T. L., Getzenberg, R. H., Ivkov, R. & Lupold, S. E., Jul 2014, In : ChemMedChem. 9, 7, p. 1356-1360 5 p.

Research output: Contribution to journalArticle

Development of a novel preclinical pancreatic cancer research model: Bioluminescence image-guided focal irradiation and tumor monitoring of orthotopic xenografts

Tuli, R., Surmak, A., Reyes, J., Hacker-Prietz, A., Armour, M., Leubner, A., Blackford, A., Tryggestad, E., Jaffee, E. M., Wong, J., DeWeese, T. L. & Herman, J. M., Apr 2012, In : Translational Oncology. 5, 2, p. 77-84 8 p.

Research output: Contribution to journalArticle

Differences in Physician Compensation Between Men and Women at United States Public Academic Radiation Oncology Departments

Guss, Z. D., Chen, Q., Hu, C., Guss, L. G., DeWeese, T. & Terezakis, S. A., Feb 1 2019, In : International Journal of Radiation Oncology Biology Physics. 103, 2, p. 314-319 6 p.

Research output: Contribution to journalArticle

DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity

Yegnasubramanian, S., Haffner, M. C., Zhang, Y., Gurel, B., Cornish, T. C., Wu, Z., Irizarry, R. A., Morgan, J., Hicks, J., DeWeese, T. L., Isaacs, W. B., Bova, G. S., De Marzo, A. M. & Nelson, W. G., Nov 1 2008, In : Cancer Research. 68, 21, p. 8954-8967 14 p.

Research output: Contribution to journalArticle

Downregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factor

Kachhap, S. K., Rosmus, N., Collis, S. J., Kortenhorst, M. S. Q., Wissing, M. D., Hedayati, M., Shabbeer, S., Mendonca, J., Deangelis, J., Marchionni, L., Lin, J., Höti, N., Nortier, J. W. R., Deweese, T. L., Hammers, H. & Carducci, M. A., Aug 11 2010, In : PloS one. 5, 6, e11208.

Research output: Contribution to journalArticle

Effects of biodegradable hydrogel spacer injection on contralateral submandibular gland sparing in radiotherapy for head and neck cancers

Rao, A. D., Coquia, S., De Jong, R., Gourin, C., Page, B., Latronico, D., Dah, S., Su, L., Clarke, S., Schultz, J., Rosati, L. M., Fakhry, C., Wong, J., DeWeese, T., Quon, H., Ding, K. & Kiess, A. P., 2017, (Accepted/In press) In : Radiotherapy and Oncology.

Research output: Contribution to journalArticle

Effects of perineural invasion on biochemical recurrence and prostate cancer-specific survival in patients treated with definitive external beam radiotherapy

Peng, L. C., Narang, A. K., Gergis, C., Radwan, N. A., Han, P., Marciscano, A. E., Robertson, S. P., He, P., Trieu, J., Ram, A. N., McNutt, T. R., Griffith, E., DeWeese, T. A., Honig, S., Singh, H., Greco, S. C., Tran, P. T., Deville, C., DeWeese, T. L. & Song, D. Y., Jun 2018, In : Urologic Oncology: Seminars and Original Investigations. 36, 6, p. 309.e7-309.e14

Research output: Contribution to journalArticle