Research output per year
Research output per year
- 1 - 50 out of 80 results
Search results
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2024
Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis
Matsubayashi, H. T., Mountain, J., Takahashi, N., Deb Roy, A., Yao, T., Peterson, A. F., Saez Gonzalez, C., Kawamata, I. & Inoue, T., Dec 2024, In: Nature communications. 15, 1, 2612.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
ActuAtor, a Listeria-inspired molecular tool for physical manipulation of intracellular organizations through de novo actin polymerization
Nakamura, H., Rho, E., Lee, C. T., Itoh, K., Deng, D., Watanabe, S., Razavi, S., Matsubayashi, H. T., Zhu, C., Jung, E., Rangamani, P., Watanabe, S. & Inoue, T., Oct 31 2023, In: Cell Reports. 42, 10, 113089.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Defunctionalizing intracellular organelles such as mitochondria and peroxisomes with engineered phospholipase A/acyltransferases
Watanabe, S., Nihongaki, Y., Itoh, K., Uyama, T., Toda, S., Watanabe, S. & Inoue, T., Dec 2022, In: Nature communications. 13, 1, 4413.Research output: Contribution to journal › Article › peer-review
Open Access -
Dynamin is primed at endocytic sites for ultrafast endocytosis
Imoto, Y., Raychaudhuri, S., Ma, Y., Fenske, P., Sandoval, E., Itoh, K., Blumrich, E. M., Matsubayashi, H. T., Mamer, L., Zarebidaki, F., Söhl-Kielczynski, B., Trimbuch, T., Nayak, S., Iwasa, J. H., Liu, J., Wu, B., Ha, T., Inoue, T., Jorgensen, E. M., Cousin, M. A., & 2 others, Sep 7 2022, In: Neuron. 110, 17, p. 2815-2835.e13Research output: Contribution to journal › Article › peer-review
Open Access -
Multiple ciliary localization signals control INPP5E ciliary targeting
Cilleros-Rodriguez, D., Martin-Morales, R., Barbeito, P., Deb Roy, A., Loukil, A., Sierra-Rodero, B., Herranz, G., Pampliega, O., Redrejo-Rodriguez, M., Goetz, S. C., Izquierdo, M., Inoue, T. & Garcia-Gonzalo, F. R., Sep 2022, In: eLife. 11, e78383.Research output: Contribution to journal › Article › peer-review
Open Access -
Non-catalytic allostery in α-TAT1 by a phospho-switch drives dynamic microtubule acetylation
Roy, A. D., Gross, E. G., Pillai, G. S., Seetharaman, S., Etienne-Manneville, S. & Inoue, T., Nov 7 2022, In: Journal of Cell Biology. 221, 11, e202202100.Research output: Contribution to journal › Article › peer-review
Open Access -
PIP2 determines length and stability of primary cilia by balancing membrane turnovers
Stilling, S., Kalliakoudas, T., Benninghoven-Frey, H., Inoue, T. & Falkenburger, B. H., Dec 2022, In: Communications biology. 5, 1, 93.Research output: Contribution to journal › Article › peer-review
Open Access -
Reconstitution of membrane symmetry breaking
Razavi, S. & Inoue, T., Jan 1 2022, Plasma Membrane Shaping. Elsevier, p. 333-353 21 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2021
A molecular trap inside microtubules probes luminal access by soluble proteins
Nihongaki, Y., Matsubayashi, H. T. & Inoue, T., Aug 2021, In: Nature chemical biology. 17, 8, p. 888-895 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial: The Cytoskeleton and Cellular Compartmentation: Cilia as Specialized Cellular Domains
Garcia-Gonzalo, F. R., Soares, H., Lopes, S. S. & Inoue, T., Oct 22 2021, In: Frontiers in Cell and Developmental Biology. 9, 777758.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Growth and site-specific organization of micron-scale biomolecular devices on living mammalian cells
Jia, S., Phua, S. C., Nihongaki, Y., Li, Y., Pacella, M., Li, Y., Mohammed, A. M., Sun, S., Inoue, T. & Schulman, R., Dec 1 2021, In: Nature communications. 12, 1, 5729.Research output: Contribution to journal › Article › peer-review
Open Access -
Synthetic design of farnesyl-electrostatic peptides for development of a protein kinase A membrane translocation switch
Kim, A. K., Wu, H. D. & Inoue, T., Dec 2021, In: Scientific reports. 11, 1, 16421.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Metabolic Compartmentalization at the Leading Edge of Metastatic Cancer Cells
Wolfe, K., Kamata, R., Coutinho, K., Inoue, T. & Sasaki, A. T., Nov 2 2020, In: Frontiers in Oncology. 10, 554272.Research output: Contribution to journal › Review article › peer-review
Open Access -
Rational design and implementation of a chemically inducible heterotrimerization system
Wu, H. D., Kikuchi, M., Dagliyan, O., Aragaki, A. K., Nakamura, H., Dokholyan, N. V., Umehara, T. & Inoue, T., Sep 1 2020, In: Nature Methods. 17, 9, p. 928-936 9 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Rational Design of a Protein Kinase A Nuclear-cytosol Translocation Reporter
Kim, A. K., Wu, H. D. & Inoue, T., Dec 1 2020, In: Scientific reports. 10, 1, 9365.Research output: Contribution to journal › Article › peer-review
Open Access -
Twist1-induced epithelial dissemination requires PRKD1 signaling
Georgess, D., Padmanaban, V., Sirka, O. K., Coutinho, K., Choi, A., Frid, G., Neumann, N. M., Inoue, T. & Ewald, A. J., Jan 15 2020, In: Cancer Research. 80, 2, p. 204-218 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2019
Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß
Kremer, L., Hennes, E., Brause, A., Ursu, A., Robke, L., Matsubayashi, H. T., Nihongaki, Y., Flegel, J., Mejdrová, I., Eickhoff, J., Baumann, M., Nencka, R., Janning, P., Kordes, S., Schöler, H. R., Sterneckert, J., Inoue, T., Ziegler, S. & Waldmann, H., Nov 11 2019, In: Angewandte Chemie - International Edition. 58, 46, p. 16617-16628 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Erratum: Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision (Cell (2017) 168 1-2 (264-279.e15) PII: S0092-8674(19)30678-6)
Phua, S. C., Chiba, S., Suzuki, M., Su, E., Roberson, E. C., Pusapati, G. V., Schurmans, S., Setou, M., Rohatgi, R., Reiter, J. F., Ikegami, K. & Inoue, T., Jun 27 2019, In: Cell. 178, 1, p. 261 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Harnessing biomolecular condensates in living cells
Nakamura, H., DeRose, R. & Inouey, T., Jul 1 2019, In: Journal of biochemistry. 166, 1, p. 13-27 15 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
Wave patterns organize cellular protrusions and control cortical dynamics
Miao, Y., Bhattacharya, S., Banerjee, T., Abubaker-Sharif, B., Long, Y., Inoue, T., Iglesias, P. A. & Devreotes, P. N., Mar 2019, In: Molecular systems biology. 15, 3, e8585.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2018
Allosteric regulators selectively prevent Ca 2+ -feedback of Ca v and Na v channels
Niu, J., Dick, I. E., Yang, W., Bamgboye, M. A., Yue, D. T., Tomaselli, G., Inoue, T. & Ben-Johny, M., Sep 2018, In: eLife. 7, e35222.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Autonomy declared by primary cilia through compartmentalization of membrane phosphoinositides
Phua, S. C., Nihongaki, Y. & Inoue, T., Feb 2018, In: Current Opinion in Cell Biology. 50, p. 72-78 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access8 Scopus citations -
Cellular application of genetically encoded sensors and impeders of AMPK
Miyamoto, T., Rho, E., Kim, A. & Inoue, T., 2018, Methods in Molecular Biology. Humana Press Inc., p. 255-272 18 p. (Methods in Molecular Biology; vol. 1732).Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Scopus citations -
Duplex signaling by CaM and Stac3 enhances CaV1.1 function and provides insights into congenital myopathy
Niu, J., Yang, W., Yue, D. T., Inoue, T. & Ben-Johny, M., Aug 1 2018, In: Journal of General Physiology. 150, 8, p. 1145-1161 17 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions
Nakamura, H., Lee, A. A., Afshar, A. S., Watanabe, S., Rho, E., Razavi, S., Suarez, A., Lin, Y. C., Tanigawa, M., Huang, B., DeRose, R., Bobb, D., Hong, W., Gabelli, S. B., Goutsias, J. & Inoue, T., Jan 1 2018, In: Nature Materials. 17, 1, p. 79-88 10 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Phospholipid-flipping activity of P4-ATPase drives membrane curvature
Takada, N., Naito, T., Inoue, T., Nakayama, K., Takatsu, H. & Shin, H. W., May 2 2018, In: EMBO Journal. 37, 9, e97705.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling
Hong, S. R., Wang, C. L., Huang, Y. S., Chang, Y. C., Chang, Y. C., Pusapati, G. V., Lin, C. Y., Hsu, N., Cheng, H. C., Chiang, Y. C., Huang, W. E., Shaner, N. C., Rohatgi, R., Inoue, T. & Lin, Y. C., Dec 1 2018, In: Nature communications. 9, 1, 1732.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2017
Altering the threshold of an excitable signal transduction network changes cell migratory modes
Miao, Y., Bhattacharya, S., Edwards, M., Cai, H., Inoue, T., Iglesias, P. A. & Devreotes, P. N., 2017, In: Nature cell biology. 19, 4, p. 329-340 12 p.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision
Phua, S. C., Chiba, S., Suzuki, M., Su, E., Roberson, E. C., Pusapati, G. V., Setou, M., Rohatgi, R., Reiter, J. F., Ikegami, K. & Inoue, T., Jan 12 2017, In: Cell. 168, 1-2, p. 264-279.e15Research output: Contribution to journal › Article › peer-review
Open Access134 Scopus citations -
2016
A novel membrane anchor for FtsZ is linked to cell wall hydrolysis in Caulobacter crescentus
Meier, E. L., Razavi, S., Inoue, T. & Goley, E. D., Jul 1 2016, In: Molecular Microbiology. 101, 2, p. 265-280 16 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Deconstructing and constructing innate immune functions using molecular sensors and actuators
Coutinho, K. & Inoue, T., 2016, Sensing and Analysis Technologies for Biomedical and Cognitive Applications 2016. Meyer-Base, A. D., Dai, L., Zheng, Y. & Chu, H. (eds.). SPIE, 987102. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 9871).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Following Optogenetic Dimerizers and Quantitative Prospects
Niu, J., Ben Johny, M., Dick, I. E. & Inoue, T., Sep 20 2016, In: Biophysical journal. 111, 6, p. 1132-1140 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access12 Scopus citations -
New Biological Frontiers Illuminated by Molecular Sensors and Actuators
Gaus, K. & Inoue, T., Sep 20 2016, In: Biophysical journal. 111, 6, p. E01-E02Research output: Contribution to journal › Editorial › peer-review
Open Access1 Scopus citations -
Opposing effects of pericentrin and microcephalin on the pericentriolar material regulate CHK1 activation in the DNA damage response
Antonczak, A. K., Mullee, L. I., Wang, Y., Comartin, D., Inoue, T., Pelletier, L. & Morrison, C. G., Apr 14 2016, In: Oncogene. 35, 15, p. 2003-2010 8 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Toward total synthesis of cell function: Reconstituting cell dynamics with synthetic biology
Kim, A. K., DeRose, R., Ueno, T., Lin, B., Komatsu, T., Nakamura, H. & Inoue, T., Feb 9 2016, In: Science signaling. 9, 414, re1.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
2015
An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli
Phua, S. C., Lin, Y. C. & Inoue, T., Oct 1 2015, In: Cell Calcium. 58, 4, p. 415-422 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access18 Scopus citations -
Compartmentalized AMPK Signaling Illuminated by Genetically Encoded Molecular Sensors and Actuators
Miyamoto, T., Rho, E., Sample, V., Akano, H., Magari, M., Ueno, T., Gorshkov, K., Chen, M., Tokumitsu, H., Zhang, J. & Inoue, T., Apr 28 2015, In: Cell Reports. 11, 4, p. 657-670 14 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Deconvoluting AMPK dynamics
Miyamoto, T., Rho, E. & Inoue, T., 2015, In: Oncotarget. 6, 31, p. 30431-30432 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access2 Scopus citations -
Interplay between chemotaxis and contact inhibition of locomotion determines exploratory cell migration
Lin, B., Yin, T., Wu, Y. I., Inoue, T. & Levchenko, A., Apr 8 2015, In: Nature communications. 6, 6619.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN
Nguyen, H. N., Yang, J. M., Miyamoto, T., Itoh, K., Rho, E., Zhang, Q., Inoue, T., Devreotes, P. N., Sesaki, H. & Iijima, M., Jul 28 2015, In: Scientific reports. 5, 12600.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling
Garcia-Gonzalo, F. R., Phua, S. C., Roberson, E. C., Garcia, G., Abedin, M., Schurmans, S., Inoue, T. & Reiter, J. F., Aug 24 2015, In: Developmental Cell. 34, 4, p. 400-409 10 p., 3368.Research output: Contribution to journal › Article › peer-review
Open Access149 Scopus citations -
2014
A method to rapidly induce organelle-specific molecular activities and membrane tethering
Komatsu, T. & Inoue, T., 2014, In: Methods in Molecular Biology. 1174, p. 231-245 15 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Apocalmodulin itself promotes ion channel opening and Ca2+ regulation
Adams, P. J., Ben-Johny, M., Dick, I. E., Inoue, T. & Yue, D. T., Oct 23 2014, In: Cell. 159, 3, p. 608-622 15 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
Bin/Amphiphysin/Rvs (BAR) family members bend membranes in cells
Suarez, A., Ueno, T., Huebner, R., McCaffery, J. M. & Inoue, T., May 6 2014, In: Scientific reports. 4, 4693.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Cellular Signaling Circuits Interfaced with Synthetic, Post-Translational, Negating Boolean Logic Devices
Razavi, S., Su, S. & Inoue, T., Sep 19 2014, In: ACS Synthetic Biology. 3, 9, p. 676-685 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Rapidly rendering cells phagocytic through a cell surface display technique and concurrent Rac activation
Onuma, H., Komatsu, T., Arita, M., Hanaoka, K., Ueno, T., Terai, T., Nagano, T. & Inoue, T., Jul 15 2014, In: Science signaling. 334, rs4.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
The CP110-interacting proteins talpid3 and cep290 play overlapping and distinct roles in cilia assembly
Kobayashi, T., Kim, S., Lin, Y. C., Inoue, T. & Dynlacht, B. D., Jan 20 2014, In: Journal of Cell Biology. 204, 2, p. 215-229 15 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
Unraveling molecular mechanism of cell migration using novel perturbation tools
Inoue, T., 2014, In: Yakugaku Zasshi. 134, 5, p. 647-654 8 p.Research output: Contribution to journal › Review article › peer-review
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2013
Chemically inducible diffusion trap at cilia reveals molecular sieve-like barrier
Inoue, T., Lin, Y. C., Niewiadomski, P., Lin, B., Nakamura, H., Phua, S. C., Jiao, J., Levchenko, A., Inoue, T. & Rohatgi, R., Jul 2013, In: Nature chemical biology. 9, 7, p. 437-443 7 p.Research output: Contribution to journal › Article › peer-review
Open Access80 Scopus citations -
Controlling enzymatic action in living cells with a kinase-inducible bimolecular switch
Sample, V., Ni, Q., Mehta, S., Inoue, T. & Zhang, J., Jan 18 2013, In: ACS chemical biology. 8, 1, p. 116-121 6 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations