Research Output per year
Research Output 1999 2017
- 49 Article
Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance
Lopez, P. H. H., Aja, S., Aoki, K., Seldin, M. M., Lei, X., V Ronnett, G., Wong, G. W. & Schnaar, R. L. 2017 In : Glycobiology. 27, 1, p. 129-139 11 p.Research output: Contribution to journal › Article
Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes
Kim, S. P., Frey, J. L., Li, Z., Kushwaha, P., Zoch, M. L., Tomlinson, R. E., Da, H., Aja, S., Noh, H. L., Kim, J. K., Hussain, M. A., Thorek, D. L. J., Wolfgang, M. J. & Riddle, R. C. Dec 26 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 52, p. E11238-E11247Research output: Contribution to journal › Article
D-chiro-inositol glycan reduces food intake by regulating hypothalamic neuropeptide expression via AKT-FoxO1 pathway
Jeon, Y., Aja, S., Ronnett, G. V. & Kim, E. K. Feb 19 2016 In : Biochemical and Biophysical Research Communications. 470, 4, p. 818-823 6 p.Research output: Contribution to journal › Article
Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet
Slocum, S. L., Skoko, J. J., Wakabayashi, N., Aja, S., Yamamoto, M., Kensler, T. W. & Chartoumpekis, D. V. Feb 1 2016 In : Archives of Biochemistry and Biophysics. 591, p. 57-65 9 p.Research output: Contribution to journal › Article
Loss of Adipose Fatty Acid Oxidation Does Not Potentiate Obesity at Thermoneutrality
Lee, J., Choi, J., Aja, S., Scafidi, S. & Wolfgang, M. J. Feb 16 2016 In : Cell Reports. 14, 6, p. 1308-1316 9 p.Research output: Contribution to journal › Article
Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast
Frey, J. L., Li, Z., Ellis, J. M., Zhang, Q., Farber, C. R., Aja, S., Wolfgang, M. J., Clemens, T. L. & Riddle, R. C. 2015 In : Molecular and Cellular Biology. 35, 11, p. 1979-1991 13 p.Research output: Contribution to journal › Article
Anaplerotic triheptanoin diet enhances mitochondrial substrate use to remodel the metabolome and improve lifespan, motor function, and sociability in MeCP2-null mice
Park, M. J., Aja, S., Li, Q., Degano, A. L., Penati, J., Zhuo, J., Roe, C. R. & Ronnett, G. V. 2014 In : PLoS One. 9, 10, e0109527Research output: Contribution to journal › Article
Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice
Lee, D. A., Yoo, S., Pak, T., Salvatierra, J., Velarde, E., Aja, S. & Blackshaw, S. 2014 In : Frontiers in Neuroscience. 8 JUN, Article 157Research output: Contribution to journal › Article
Increasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammation
McFadden, J. W., Aja, S., Li, Q., Bandaru, V. V. R., Kim, E. K., Haughey, N. J., Kuhajda, F. P. & Ronnett, G. V. Dec 26 2014 In : PLoS One. 9, 12, e115642Research output: Contribution to journal › Article
Targeted deletion of C1q/TNF-related protein 9 increases food intake, decreases insulin sensitivity, and promotes hepatic steatosis in mice
Wei, Z., Lei, X., Petersen, P. S., Aja, S. & Wong, G. W. Apr 1 2014 In : American Journal of Physiology - Endocrinology and Metabolism. 306, 7Research output: Contribution to journal › Article
CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism
Peterson, J. M., Seldin, M. M., Wei, Z., Aja, S. & Wong, G. W. Aug 1 2013 In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 305, 3Research output: Contribution to journal › Article
CTRP9 transgenic mice are protected from diet-induced obesity and metabolic dysfunction
Peterson, J. M., Wei, Z., Seldin, M. M., Byerly, M. S., Aja, S. & Wong, G. W. Sep 1 2013 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 305, 5Research output: Contribution to journal › Article
Estrogen-related receptor β deletion modulates whole-body energy balance via estrogen-related receptor γ and attenuates neuropeptide Y gene expression
Byerly, M. S., Al Salayta, M., Swanson, R. D., Kwon, K., Peterson, J. M., Wei, Z., Aja, S., Moran, T. H., Blackshaw, S. & Wong, G. W. Apr 2013 In : European Journal of Neuroscience. 37, 7, p. 1033-1047 15 p.Research output: Contribution to journal › Article
Identification of hypothalamic neuron-derived neurotrophic factor as a novel factor modulating appetite
Byerly, M. S., Swanson, R. D., Semsarzadeh, N. N., McCulloh, P. S., Kwon, K., Aja, S., Moran, T. H., William Wong, G. & Blackshaw, S. Jun 15 2013 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 304, 12Research output: Contribution to journal › Article
A novel obesity model: Synphilin-1-induced hyperphagia and obesity in mice
Li, X., Tamashiro, K. L. K., Liu, Z., Bello, N. T., Wang, X., Aja, S., Bi, S., Ladenheim, E. E., Ross, C. A., Moran, T. H. & Smith, W. W. Sep 2012 In : International Journal of Obesity. 36, 9, p. 1215-1221 7 p.Research output: Contribution to journal › Article
CTRP1 protein enhances fatty acid oxidation via AMP-activated protein kinase (AMPK) activation and acetyl-CoA carboxylase (ACC) inhibition
Peterson, J. M., Aja, S., Wei, Z. & Wong, G. W. Jan 6 2012 In : Journal of Biological Chemistry. 287, 2, p. 1576-1587 12 p.Research output: Contribution to journal › Article
Metabolic Consequences of High-Fat Diet Are Attenuated by Suppression of HIF-1α
Shin, M. K., Drager, L. F., Yao, Q., Bevans-Fonti, S., Yoo, D. Y., Jun, J. C., Aja, S., Bhanot, S. & Polotsky, V. Y. Oct 1 2012 In : PLoS One. 7, 10, e46562Research output: Contribution to journal › Article
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
Jiang, M. , Wang, J. , Fu, J. , Du, L. , Jeong, H. , West, T. , Xiang, L. , Peng, Q. , Hou, Z. , Cai, H. , Seredenina, T. , Arbez, N. , Zhu, S. , Sommers, K. , Qian, J. , Zhang, J. , Mori, S. , Yang, X. W. , Tamashiro, K. L. K. , Aja, S. & 10 others Jan 2012 In : Nature Medicine. 18, 1, p. 153-158 6 p.Research output: Contribution to journal › Article
Physiological oxygen level is critical for modeling neuronal metabolism in vitro
Zhu, J., Aja, S., Kim, E. K., Park, M. J., Ramamurthy, S., Jia, J., Hu, X., Geng, P. & Ronnett, G. V. Feb 2012 In : Journal of Neuroscience Research. 90, 2, p. 422-434 13 p.Research output: Contribution to journal › Article
Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche
Lee, D. A., Bedont, J. L., Pak, T., Wang, H., Song, J., Miranda-Angulo, A., Takiar, V., Charubhumi, V., Balordi, F., Takebayashi, H., Aja, S., Ford, E., Fishell, G. & Blackshaw, S. May 2012 In : Nature Neuroscience. 15, 5, p. 700-702 3 p.Research output: Contribution to journal › Article
The brain's response to an essential amino acid-deficient diet and the circuitous route to a better meal
Gietzen, D. W. & Aja, S. M. Oct 2012 In : Molecular Neurobiology. 46, 2, p. 332-348 17 p.Research output: Contribution to journal › Article
Knockdown of NPY expression in the dorsomedial hypothalamus promotes development of brown adipocytes and prevents diet-induced obesity
Chao, P. T., Yang, L., Aja, S., Moran, T. H. & Bi, S. May 4 2011 In : Cell Metabolism. 13, 5, p. 573-583 11 p.Research output: Contribution to journal › Article
Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity
Kuhajda, F. P., Aja, S., Tu, Y., Han, W. F., Medghalchi, S. M., El Meskini, R., Landree, L. E., Peterson, J. M., Daniels, K., Wong, K., Wydysh, E. A., Townsend, C. A. & Ronnett, G. V. Jul 2011 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 301, 1Research output: Contribution to journal › Article
The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells
Zhang, Z., Wakabayashi, N., Wakabayashi, J., Tamura, Y., Song, W. J., Sereda, S., Clerc, P., Polster, B. M., Aja, S. M., Pletnikov, M. V., Kensler, T. W., Shirihai, O. S., Iijima, M., Hussain, M. A. & Sesaki, H. Jul 1 2011 In : Molecular Biology of the Cell. 22, 13, p. 2235-2245 11 p.Research output: Contribution to journal › Article
Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism
Chiang, P. M., Ling, J., Jeong, Y. H., Price, D. L., Aja, S. M. & Wong, P. C. Sep 14 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 37, p. 16320-16324 5 p.Research output: Contribution to journal › Article
Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition
Fulzele, K., Riddle, R. C., DiGirolamo, D. J., Cao, X., Wan, C., Chen, D., Faugere, M. C., Aja, S., Hussain, M. A., Brüning, J. C. & Clemens, T. L. Jul 2010 In : Cell. 142, 2, p. 309-319 11 p.Research output: Contribution to journal › Article
AMPK in the brain: Its roles in energy balance and neuroprotection
Ronnett, G. V., Ramamurthy, S., Kleman, A. M., Landree, L. E. & Aja, S. May 2009 In : Journal of Neurochemistry. 109, SUPPL. 1, p. 17-23 7 p.Research output: Contribution to journal › Article
Bromocriptine administration reduces hyperphagia and adiposity and differentially affects dopamine D2 receptor and transporter binding in leptin-receptor-deficient Zucker rats and rats with diet-induced obesity
Davis, L. M., Michaelides, M., Cheskin, L. J., Moran, T. H., Aja, S., Watkins, P. A., Pei, Z., Contoreggi, C., McCullough, K., Hope, B., Wang, G. J., Volkow, N. D. & Thanos, P. K. Feb 2009 In : Neuroendocrinology. 89, 2, p. 152-162 11 p.Research output: Contribution to journal › Article
Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide
Shin, S., Wakabayashi, J., Yates, M. S., Wakabayashi, N., Dolan, P. M., Aja, S., Liby, K. T., Sporn, M. B., Yamamoto, M. & Kensler, T. W. Oct 12 2009 In : European Journal of Pharmacology. 620, 1-3, p. 138-144 7 p.Research output: Contribution to journal › Article
AMP-activated protein kinase in the brain
Ronnett, G. V. & Aja, S. Sep 2008 In : International Journal of Obesity. 32, SUPPL.4Research output: Contribution to journal › Article
Intraperitoneal injections of low doses of C75 elicit a behaviorally specific and vagal afferent-independent inhibition of eating in rats
Mansouri, A., Aja, S., Moran, T. H., Ronnett, G., Kuhajda, F. P., Arnold, M., Geary, N., Langhans, W. & Leonhardt, M. Sep 2008 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 295, 3Research output: Contribution to journal › Article
Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight
Aja, S., Landree, L. E., Kleman, A. M., Medghalchi, S. M., Vadlamudi, A., McFadden, J. M., Aplasca, A., Hyun, J., Plummer, E., Daniels, K., Kemm, M., Townsend, C. A., Thupari, J. N., Kuhajda, F. P., Moran, T. H. & Ronnett, G. V. Feb 2008 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294, 2Research output: Contribution to journal › Article
Physiological glucose is critical for optimized neuronal viability and AMPK responsiveness in vitro
Kleman, A. M., Yuan, J. Y., Aja, S., Ronnett, G. V. & Landree, L. E. Jan 30 2008 In : Journal of Neuroscience Methods. 167, 2, p. 292-301 10 p.Research output: Contribution to journal › Article
Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake
Gao, S., Kinzig, K. P., Aja, S., Scott, K. A., Keung, W., Kelly, S., Strynadka, K., Chohnan, S., Smith, W. W., Tamashiro, K. L. K., Ladenheim, E. E., Ronnett, G. V., Tu, Y., Birnbaum, M. J., Lopaschuk, G. D. & Moran, T. H. Oct 30 2007 In : Proceedings of the National Academy of Sciences of the United States of America. 104, 44, p. 17358-17363 6 p.Research output: Contribution to journal › Article
Blockade of central GLP-1 receptors prevents CART-induced hypophagia and brain c-Fos expression
Aja, S., Ewing, C., Lin, J., Hyun, J. & Moran, T. H. Jan 2006 In : Peptides. 27, 1, p. 157-164 8 p.Research output: Contribution to journal › Article
Intracerebroventricular C75 decreases meal frequency and reduces AgRP gene expression in rats
Aja, S., Bi, S., Knipp, S. B., McFadden, J. M., Ronnett, G. V., Kuhajda, F. P. & Moran, T. H. 2006 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 291, 1Research output: Contribution to journal › Article
Leptin modulation of peripheral controls of meal size
Moran, T. H., Aja, S. & Ladenheim, E. E. Nov 30 2006 In : Physiology and Behavior. 89, 4, p. 511-516 6 p.Research output: Contribution to journal › Article
Recent advances in obesity: Adiposity signaling and fat metabolism in energy homeostasis
Aja, S. & Moran, T. H. 2006 In : Advances in Psychosomatic Medicine. 27, p. 1-23 23 p.Research output: Contribution to journal › Article
Serotonin-3 receptors in gastric mechanisms of cholecystokinin-induced satiety
Aja, S. 2006 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 291, 1Research output: Contribution to journal › Article
Anorexigenic C75 alters c-Fos in mouse hypothalamic and hindbrain subnuclei
Miller, I., Ronnett, G. V., Moran, T. H. & Aja, S. Apr 9 2004 In : NeuroReport. 15, 5, p. 925-929 5 p.Research output: Contribution to journal › Article
C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase
Kim, E. K., Miller, I., Aja, S., Landree, L. E., Pinn, M., McFadden, J., Kuhajda, F. P., Moran, T. H. & Ronnett, G. V. May 7 2004 In : Journal of Biological Chemistry. 279, 19, p. 19970-19976 7 p.Research output: Contribution to journal › Article
Fourth ventricular CART reduces food and water intake and produces a conditioned taste aversion in rats
Aja, S., Robinson, B. M., Mills, K. J., Ladenheim, E. E. & Moran, T. H. Oct 2002 In : Behavioral Neuroscience. 116, 5, p. 918-921 4 p.Research output: Contribution to journal › Article
Erratum: Intracerebroventricular CART peptide reduces rat ingestive behavior and alters licking microstructure (American Journal of Physiology - Regulatory, Integrative and parative Physiology (2001) (R1613-R1619))
Aja, S., Schwartz, G. J., Kuhar, M. J. & Moran, T. H. 2001 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 281, 4 50-4Research output: Contribution to journal › Article
Intracerebroventricular CART peptide reduces food intake and alters motor behavior at a hindbrain site
Aja, S., Sahandy, S., Ladenheim, E. E., Schwartz, G. J. & Moran, T. H. Dec 2001 In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 281, 6 PART 2Research output: Contribution to journal › Article
Intracerebroventricular CART peptide reduces food intake and alters motor behavior at a hindbrain site
Susan, A. J. A., Sahandy, S., Ladenheim, E. E., Schwartz, G. J. & Moran, T. H. 2001 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 281, 6 50-6Research output: Contribution to journal › Article
Intracerebroventricular CART peptide reduces rat ingestive behavior and alters licking microstructure
Aja, S., Schwartz, G. J., Kuhar, M. J. & Moran, T. H. 2001 In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 280, 6 49-6Research output: Contribution to journal › Article
Basolateral and central amygdaloid lesions leave aversion to dietary amino acid imbalance intact
Aja, S., Sisouvong, S., Barrett, J. A. & Gietzen, D. W. 2000 In : Physiology and Behavior. 71, 5, p. 533-541 9 p.Research output: Contribution to journal › Article
CCK(A) and 5-HT3 receptors interact in anorectic responses to amino acid deficiency
Aja, S. M., Barrett, J. A. & Gietzen, D. W. Mar 1999 In : Pharmacology Biochemistry and Behavior. 62, 3, p. 487-491 5 p.Research output: Contribution to journal › Article
DA1 receptor activity opposes anorectic responses to amino acid-imbalanced diets
Aja, S. M., Chan, P., Barrett, J. A. & Gietzen, D. W. Mar 1999 In : Pharmacology Biochemistry and Behavior. 62, 3, p. 493-498 6 p.Research output: Contribution to journal › Article