Research Output 1998 2017

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2017

Defining the optimal dose of rifapentine for pulmonary tuberculosis: Exposure-response relations from two phase II clinical trials

Savic, R. M., Weiner, M., Mackenzie, W. R., Engle, M., Whitworth, W. C., Johnson, J. L., Nsubuga, P., Nahid, P., Nguyen, N. V., Peloquin, C. A., Dooley, K. E. & Dorman, S. E. 2017 In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Phase II Clinical Trials
Pulmonary Tuberculoses
Pharmacokinetics
Lung
Rifampin

Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance

Manson, A. L. , Cohen, K. A. , Abeel, T. , Desjardins, C. A. , Armstrong, D. T. , Barry, C. E. , Brand, J. , Chapman, S. B. , Cho, S. N. , Gabrielian, A. , Gomez, J. , Jodals, A. M. , Joloba, M. , Jureen, P. , Lee, J. S. , Malinga, L. , Maiga, M. , Nordenberg, D. , Noroc, E. , Romancenco, E. & 27 others Salazar, A., Ssengooba, W., Velayati, A. A., Winglee, K., Zalutskaya, A., Via, L. E., Cassell, G. H., Dorman, S. E., Ellner, J., Farnia, P., Galagan, J. E., Rosenthal, A., Crudu, V., Homorodean, D., Hsueh, P. R., Narayanan, S., Pym, A. S., Skrahina, A., Swaminathan, S., van der Walt, M., Alland, D., Bishai, W. R., Cohen, T., Hoffner, S., Birren, B. W., Earl, A. M. & TBResist Global Genome Consortium Jan 16 2017 In : Nature Genetics.

Research output: Contribution to journalArticle

Multidrug-Resistant Tuberculosis
Multiple Drug Resistance
Mycobacterium tuberculosis
Mutation
Molecular Pathology

In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis

Kaushik, A., Ammerman, N. C., Tasneen, R., Story-Roller, E., Dooley, K. E., Dorman, S. E., Nuermberger, E. L. & Lamichhane, G. Aug 1 2017 In : Journal of Antimicrobial Chemotherapy. 72, 8, p. 2320-2325 6 p., dkx152

Research output: Contribution to journalArticle

Rifampin
Mycobacterium tuberculosis
In Vitro Techniques
Carbapenems
Drug Therapy

Serologic Responses in Childhood Pulmonary Tuberculosis

Nonyane, B. A. S., Nicol, M. P., Andreas, N. J., Rimmele, S., Schneiderhan-Marra, N., Workman, L. J., Perkins, M. D., Joos, T., Broger, T., Ellner, J. J., Alland, D., Kampmann, B., Dorman, S. E. & Zar, H. J. Jul 15 2017 In : Pediatric Infectious Disease Journal.

Research output: Contribution to journalArticle

Pulmonary Tuberculoses
Tuberculosis
Antigens
Mycobacterium tuberculosis
Area Under Curve
2016

Analytical and clinical evaluation of the epistem genedrive assay for detection of mycobacterium tuberculosis

Shenai, S. , Armstrong, D. T. , Valli, E. , Dolinger, D. L. , Nakiyingi, L. , Dietze, R. , Dalcolmo, M. P. , Nicol, M. P. , Zemanay, W. , Manabe, Y. , Hadad, D. J. , Marques-Rodrigues, P. , Palaci, M. , Peres, R. L. , Gaeddert, M. , Armakovitch, S. , Nonyane, B. A. S. , Denkinger, C. M. , Banada, P. , Joloba, M. L. & 4 others Ellner, J., Boehme, C., Alland, D. & Dorman, S. E. Apr 1 2016 In : Journal of Clinical Microbiology. 54, 4, p. 1051-1057 7 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Confidence Intervals
Sputum
Mycobacterium
Microscopy

A phase 2 randomized trial of a rifapentine plus moxifloxacin-based regimen for treatment of pulmonary tuberculosis

Conde, M. B., Mello, F. C. Q., Duarte, R. S., Cavalcante, S. C., Rolla, V., Dalcolmo, M., Loredo, C., Durovni, B., Armstrong, D. T., Efron, A., Barnes, G. L., Marzinke, M. A., Savic, R. M., Dooley, K. E., Cohn, S., Moulton, L. H., Chaisson, R. E. & Dorman, S. E. May 1 2016 In : PLoS One. 11, 5, e0154778

Research output: Contribution to journalArticle

Pulmonary Tuberculoses
tuberculosis
Blood Flow Velocity
Pyrazinamide
Isoniazid

Comparing TSPOT assay results between an Elispot reader and manual counts

Agarwal, S., Nguyen, D. T., Lew, J. D., Teeter, L. D., Yamal, J. M., Restrepo, B. I., Brown, E. L., Dorman, S. E. & Graviss, E. A. 2016 In : Tuberculosis.

Research output: Contribution to journalArticle

Interferon-gamma Release Tests
Latent Tuberculosis
Individuality
Logistic Models
Delivery of Health Care

Differential positive TSPOT assay responses to ESAT-6 and CFP-10 in health care workers

Agarwal, S., Nguyen, D. T., Lew, J. D., Teeter, L. D., Yamal, J. M., Restrepo, B. I., Brown, E. L., Dorman, S. E. & Graviss, E. A. 2016 In : Tuberculosis.

Research output: Contribution to journalArticle

Delivery of Health Care
Antigens
Tuberculin Test
Skin Tests
Latent Tuberculosis

Negative tuberculin skin test and prediction of reversion of QuantiFERON interferon gamma release assay in US Healthcare Workers

Thanassi, W., Noda, A., Hernandez, B., Friedman, L., Dorman, S. & Yesavage, J. Apr 1 2016 In : Infection Control and Hospital Epidemiology. 37, 4, p. 478-482 5 p.

Research output: Contribution to journalArticle

Interferon-gamma Release Tests
Tuberculin Test
Skin Tests
Delivery of Health Care

Occupational Risk Factors for Tuberculosis among Healthcare Workers in KwaZulu-Natal, South Africa

Tudor, C., Van Der Walt, M. L., Margot, B., Dorman, S. E., Pan, W. K., Yenokyan, G. & Farley, J. E. May 15 2016 In : Clinical Infectious Diseases. 62, p. S255-S261

Research output: Contribution to journalArticle

South Africa
Tuberculosis
Delivery of Health Care
HIV
Odds Ratio
2015
Tuberculosis
Routine Diagnostic Tests
Epidemiology
Health

Daily rifapentine for treatment of pulmonary tuberculosis: A randomized, dose-ranging trial

Dorman, S. E., Savic, R. M., Goldberg, S., Stout, J. E., Schluger, N., Muzanyi, G., Johnson, J. L., Nahid, P., Hecker, E. J., Heilig, C. M., Bozeman, L., Feng, P. J. I., Moro, R. N., MacKenzie, W., Dooley, K. E., Nuermberger, E. L., Vernon, A. & Weiner, M. Feb 1 2015 In : American Journal of Respiratory and Critical Care Medicine. 191, 3, p. 333-343 11 p.

Research output: Contribution to journalArticle

Rifampin
Pulmonary Tuberculoses
Sputum
Pyrazinamide
Ethambutol

Evaluation of a point-of-care tuberculosis test-and-treat algorithm on early mortality in people with HIV accessing antiretroviral therapy (TB Fast Track study): Study protocol for a cluster randomised controlled trial

Fielding, K. L., Charalambous, S., Hoffmann, C. J., Johnson, S., Tlali, M., Dorman, S. E., Vassall, A., Churchyard, G. J. & Grant, A. D. Mar 28 2015 In : Trials. 16, 1, 125

Research output: Contribution to journalArticle

Tuberculosis
Randomized Controlled Trials
HIV
Mortality
Routine Diagnostic Tests

Improving the sensitivity of the Xpert MTB/RIF assay on sputum pellets by decreasing the amount of added sample reagent: A laboratory and clinical evaluation

Dharan, N. J., Amisano, D., Mboowa, G., Ssengooba, W., Blakemore, R., Kubiak, R. W., Armstrong, D. T., Jones, M., Manabe, Y. C., Joloba, M. L., Ellner, J. J., Dorman, S. E. & Alland, D. Apr 1 2015 In : Journal of Clinical Microbiology. 53, 4, p. 1258-1263 6 p.

Research output: Contribution to journalArticle

Sputum
Mycobacterium tuberculosis
Limit of Detection
Confidence Intervals
Bacillus

Molecular epidemiology of Mycobacterium tuberculosis among South African gold miners

Mathema, B., Lewis, J. J., Connors, J., Chihota, V. N., Shashkina, E., Van Der Meulen, M., Graviss, E. A., Ha, N. P., Kreiswirth, B. N., Grant, A. D., Fielding, K. L., Dorman, S. E. & Churchyard, G. J. Jan 1 2015 In : Annals of the American Thoracic Society. 12, 1, p. 12-20 9 p.

Research output: Contribution to journalArticle

Molecular Epidemiology
Mycobacterium tuberculosis
Gold
Cluster Analysis
South Africa

Novel dosing strategies increase exposures of the potent antituberculosis drug rifapentine but are poorly tolerated in healthy volunteers

Dooley, K. E., Savic, R. M., Park, J. G., Cramer, Y., Hafner, R., Hogg, E., Janik, J., Marzinke, M. A., Patterson, K., Benson, C. A., Hovind, L., Dorman, S. E. & Haas, D. W. Jun 1 2015 In : Antimicrobial Agents and Chemotherapy. 59, 6, p. 3399-3405 7 p.

Research output: Contribution to journalArticle

Healthy Volunteers
Fats
Breakfast
Tuberculosis
Area Under Curve

Predictors and outcomes of mycobacteremia among HIV-infected smear- negative presumptive tuberculosis patients in Uganda

Nakiyingi, L., Ssengooba, W., Nakanjako, D., Armstrong, D., Holshouser, M., Kirenga, B. J., Shah, M., Mayanja-Kizza, H., Joloba, M. L., Ellner, J. J., Dorman, S. E. & Manabe, Y. C. Feb 15 2015 In : BMC Infectious Diseases. 15, 1, 62

Research output: Contribution to journalArticle

Uganda
Tuberculosis
HIV
Sputum
CD4 Lymphocyte Count

Predictors for MTB culture-positivity among HIV-infected smear-negative presumptive tuberculosis patients in Uganda: Application of new tuberculosis diagnostic technology

Nakiyingi, L., Nonyane, B. A. S., Ssengooba, W., Kirenga, B. J., Nakanjako, D., Lubega, G., Byakika-Kibwika, P., Joloba, M. L., Ellner, J. J., Dorman, S. E., Mayanja-Kizza, H. & Manabe, Y. C. Jul 29 2015 In : PLoS One. 10, 7, e0133756

Research output: Contribution to journalArticle

Uganda
Mycobacterium tuberculosis
Tuberculosis
HIV
Technology

Two-stage activity-safety study of daily rifapentine during intensive phase treatment of pulmonary tuberculosis

Dawson, R., Narunsky, K., Carman, D., Gupte, N., Whitelaw, A., Efron, A., Barnes, G. L., Hoffman, J., Chaisson, R. E., McIlleron, H. & Dorman, S. E. Jul 1 2015 In : International Journal of Tuberculosis and Lung Disease. 19, 7, p. 780-786 7 p.

Research output: Contribution to journalArticle

Pulmonary Tuberculoses
Safety
Rifampin
Sputum
Tuberculosis
2014

Clinical utility of a novel molecular assay in various combination strategies with existing methods for diagnosis of HIV-related tuberculosis in Uganda

Ssengooba, W., Nakiyingi, L., Armstrong, D. T., Cobelens, F. G., Alland, D., Manabe, Y. C., Dorman, S. E., Ellner, J. J. & Joloba, M. L. Sep 15 2014 In : PLoS One. 9, 9, e107595

Research output: Contribution to journalArticle

Uganda
Microscopy
Tuberculosis
HIV
microscopy

Comparative performance of urinary lipoarabinomannan assays and Xpert MTB/RIF in HIV-infected individuals

Shah, M., Ssengooba, W., Armstrong, D., Nakiyingi, L., Holshouser, M., Ellner, J. J., Joloba, M., Manabe, Y. C. & Dorman, S. E. 2014 In : AIDS. 28, 9, p. 1307-1314 8 p.

Research output: Contribution to journalArticle

Tuberculosis
HIV
Sputum
Uganda
Microscopy

Diagnostic accuracy of a rapid urine lipoarabinomannan test for tuberculosis in HIV-infected adults

Nakiyingi, L., Moodley, V. M., Manabe, Y. C., Nicol, M. P., Holshouser, M., Armstrong, D. T., Zemanay, W., Sikhondze, W., Mbabazi, O., Nonyane, B. A. S., Shah, M., Joloba, M. L., Alland, D., Ellner, J. J. & Dorman, S. E. Jul 1 2014 In : Journal of Acquired Immune Deficiency Syndromes. 66, 3, p. 270-279 10 p.

Research output: Contribution to journalArticle

Tuberculosis
HIV
Urine
Microscopy
Uganda

Interferon-γ release assays and tuberculin skin testing for diagnosis of latent tuberculosis infection in healthcare workers in the united states

Dorman, S. E., Belknap, R., Graviss, E. A., Reves, R., Schluger, N., Weinfurter, P., Wang, Y., Cronin, W., Hirsch-Moverman, Y., Teeter, L. D., Parker, M., Garrett, D. O. & Daley, C. L. Jan 1 2014 In : American Journal of Respiratory and Critical Care Medicine. 189, 1, p. 77-87 11 p.

Research output: Contribution to journalArticle

Interferon-gamma Release Tests
Latent Tuberculosis
Tuberculin
Delivery of Health Care
Skin

Point-of-care lateral flow assays for tuberculosis and cryptococcal antigenuria predict death in HIV infected adults in Uganda

Manabe, Y. C., Nonyane, B. A. S., Nakiyingi, L., Mbabazi, O., Lubega, G., Shah, M., Moulton, L. H., Joloba, M., Ellner, J. & Dorman, S. E. Jul 7 2014 In : PLoS One. 9, 7, e101459

Research output: Contribution to journalArticle

Uganda
Tuberculosis
HIV
Antigens
Beryllium

Population pharmacokinetics of rifapentine and desacetyl rifapentine in healthy volunteers: Nonlinearities in clearance and bioavailability

Savic, R. M., Lu, Y., Bliven-Sizemore, E., Weiner, M., Nuermberger, E., Burman, W., Dorman, S. E. & Dooley, K. E. 2014 In : Antimicrobial Agents and Chemotherapy. 58, 6, p. 3035-3042 8 p.

Research output: Contribution to journalArticle

Biological Availability
Healthy Volunteers
Pharmacokinetics
Tuberculosis
Clinical Trials

Prospective cross-sectional evaluation of the small membrane filtration method for diagnosis of pulmonary tuberculosis

Jones-López, E., Manabe, Y. C., Palaci, M., Kayiza, C., Armstrong, D., Nakiyingi, L., Ssengooba, W., Gaeddert, M., Kubiak, R., Almeida, P., Alland, D., Dietze, R., Joloba, M., Ellner, J. J. & Dorman, S. E. 2014 In : Journal of Clinical Microbiology. 52, 7, p. 2513-2520 8 p.

Research output: Contribution to journalArticle

Pulmonary Tuberculoses
Membranes
Sputum
Microscopy
Uganda

Quantification of rifapentine, a potent antituberculosis drug, from dried blood spot samples using liquid chromatographic-tandem mass spectrometric analysis

Parsons, T. L., Marzinke, M. A., Hoang, T., Bliven-Sizemore, E., Weiner, M., Mac Kenzie, W. R., Dorman, S. E. & Dooley, K. E. Nov 1 2014 In : Antimicrobial Agents and Chemotherapy. 58, 11, p. 6747-6757 11 p.

Research output: Contribution to journalArticle

Phlebotomy
Blood Volume
Hematocrit
Tuberculosis
Pharmacokinetics

Risk factors for treatment default in close contacts with latent tuberculous infection

Fiske, C. T. , Yan, F. X. , Hirsch-Moverman, Y. , Sterling, T. R. , Reichler, M. R. , Bakhtawar, I. , LeDoux, C. , McAuley, J. , Beison, J. , FitzGerald, J. M. , Naus, M. , Nakajima, M. , Schluger, N. , Moran, J. , Blumberg, H. , Tapia, J. , Singha, L. , Hershfeld, E. , Roche, B. , Mangura, B. & 16 others Sevilla, A., Chavez-Lindell, T., Maruri, F., Dorman, S., Cronin, W., Munk, E., Chen, B., Yuan, Y., Yan, F., Shen, Y., Zhao, H., Zhang, H., Fagley, M., Reichler, M., Hirsch, C. & Luo, C. Apr 1 2014 In : International Journal of Tuberculosis and Lung Disease. 18, 4, p. 421-427 7 p.

Research output: Contribution to journalArticle

Infection
Isoniazid
Tuberculosis
Home Care Services
Pulmonary Tuberculoses

Sensititre MYCOTB MIC plate for testing mycobacterium tuberculosis susceptibility to first-And second-Line drugs

Lee, J., Armstrong, D. T., Ssengooba, W., Park, J. A., Yu, Y., Mumbowa, F., Namaganda, C., Mboowa, G., Nakayita, G., Armakovitch, S., Chien, G., Cho, S. N., Via, L. E., Barry, C. E., Ellner, J. J., Alland, D., Dorman, S. E. & Joloba, M. L. Jan 2014 In : Antimicrobial Agents and Chemotherapy. 58, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Agar
Ethambutol
Republic of Korea
Uganda

Tuberculosis among health care workers in KwaZulu-Natal, South Africa: A retrospective cohort analysis

Tudor, C., Van Walt, M. D., Margot, B., Dorman, S. E., Pan, W. K., Yenokyan, G. & Farley, J. E. Aug 30 2014 In : BMC Public Health. 14, 1, 891

Research output: Contribution to journalArticle

South Africa
Tuberculosis
Cohort Studies
Delivery of Health Care
Incidence
2013

A summary of meeting proceedings on addressing variability around the cut point in serial interferon-γ release assay testing

Daley, C. L. , Reves, R. R. , Beard, M. A. , Boyle, J. , Clark, R. B. , Beebe, J. L. , Catanzaro, A. , Chen, L. , Desmond, E. , Dorman, S. E. , Hudson, T. W. , Lardizabal, A. A. , Kapoor, H. , Marder, D. C. , Miranda, C. , Narita, M. , Reichman, L. , Schwab, D. , Seaworth, B. J. , Terpeluk, P. & 2 others Thanassi, W. & Kawamura, L. M. Jun 2013 In : Infection Control and Hospital Epidemiology. 34, 6, p. 625-630 6 p.

Research output: Contribution to journalArticle

Interferon-gamma Release Tests
Multidrug-Resistant Tuberculosis
South Africa
Routine Diagnostic Tests
Tuberculosis
Costs and Cost Analysis

Cost-effectiveness of novel algorithms for rapid diagnosis of tuberculosis in HIV-infected individuals in Uganda

Shah, M., Dowdy, D., Joloba, M., Ssengooba, W., Manabe, Y. C., Ellner, J. & Dorman, S. E. Nov 28 2013 In : AIDS. 27, 18, p. 2883-2892 10 p.

Research output: Contribution to journalArticle

Uganda
Cost-Benefit Analysis
Tuberculosis
HIV
Microscopy

Cost-effectiveness of routine diagnostic evaluation of pulmonary tuberculosis in a primary care unit in Brazil

Guerra, R. L., Dorman, S. E., Luiz, R. R. & Conde, M. B. Oct 1 2013 In : International Journal of Tuberculosis and Lung Disease. 17, 10, p. 1336-1340 5 p.

Research output: Contribution to journalArticle

Pulmonary Tuberculoses
Cost-Benefit Analysis
Brazil
Primary Health Care
Costs and Cost Analysis
Tuberculosis
HIV
Urine
Costs and Cost Analysis
Quality-Adjusted Life Years

Determine TB-LAM lateral flow urine antigen assay for HIV-associated tuberculosis: Recommendations on the design and reporting of clinical studies

Lawn, S. D., Dheda, K., Kerkhoff, A. D., Peter, J. G., Dorman, S., Boehme, C. C. & Nicol, M. P. Sep 3 2013 In : BMC Infectious Diseases. 13, 1, 407

Research output: Contribution to journalArticle

HIV Antigens
Tuberculosis
Urine
HIV
Urine Specimen Collection

Optimal triage test characteristics to improve the cost-effectiveness of the Xpert MTB/RIF assay for TB diagnosis: A decision analysis

Van't Hoog, A. H., Cobelens, F., Vassall, A., Van Kampen, S., Dorman, S. E., Alland, D. & Ellner, J. Dec 18 2013 In : PLoS One. 8, 12, e82786

Research output: Contribution to journalArticle

Decision Support Techniques
Triage
Cost-Benefit Analysis
testing
Costs

The health-system benefits and cost-effectiveness of using Mycobacterium tuberculosis direct nucleic acid amplification testing to diagnose tuberculosis disease in the United States

Marks, S. M., Cronin, W., Venkatappa, T., Maltas, G., Chon, S., Sharnprapai, S., Gaeddert, M., Tapia, J., Dorman, S. E., Etkind, S., Crosby, C., Blumberg, H. M. & Bernardo, J. Aug 15 2013 In : Clinical Infectious Diseases. 57, 4, p. 532-542 11 p.

Research output: Contribution to journalArticle

Insurance Benefits
Mycobacterium tuberculosis
Health Care Costs
Nucleic Acids
Cost-Benefit Analysis
2012

A national infection control evaluation of drug-resistant tuberculosis hospitals in South Africa

Farley, J. E., Tudor, C., Mphahlele, M., Franz, K., Perrin, N. A., Dorman, S. & Van Der Walt, M. Jan 2012 In : International Journal of Tuberculosis and Lung Disease. 16, 1, p. 82-89 8 p.

Research output: Contribution to journalArticle

Chronic Disease Hospitals
Multidrug-Resistant Tuberculosis
Infection Control
South Africa
Delivery of Health Care

Genotype MTBDRplus for direct detection of Mycobacterium tuberculosis and drug resistance in strains from gold miners in South Africa

Dorman, S. E., Chihot, V. N., Lewis, J. J., Van Meulen, M. D., Mathem, B., Beylis, N., Fielding, K. L., Grant, A. D. & Churchyard, G. J. Apr 2012 In : Journal of Clinical Microbiology. 50, 4, p. 1189-1194 6 p.

Research output: Contribution to journalArticle

South Africa
Mycobacterium tuberculosis
Drug Resistance
Gold
Genotype

Performance characteristics of the cepheid Xpert MTB/RIF test in a tuberculosis prevalence survey

Dorman, S. E., Chihota, V. N., Lewis, J. J., Shah, M., Clark, D., Grant, A. D., Churchyard, G. J. & Fielding, K. L. Aug 15 2012 In : PLoS One. 7, 8, e43307

Research output: Contribution to journalArticle

Echoencephalography
Mycobacterium tuberculosis
Tuberculosis
tuberculosis
Biophysics

Programmatic impact of Quantiferon-TB Gold in-Tube implementation on latent tuberculosis diagnosis and treatment in a public health clinic

Shah, M., DiPietro, D., Greenbaum, A., Ketemepi, S., Martins-Evora, M., Marsiglia, V. & Dorman, S. E. May 7 2012 In : PLoS One. 7, 5, e36551

Research output: Contribution to journalArticle

Latent Tuberculosis
Gold
Tuberculosis
Public Health
gold

"Proof-Of-Concept" Evaluation of an Automated Sputum Smear Microscopy System for Tuberculosis Diagnosis

Lewis, J. J., Chihota, V. N., van der Meulen, M., Fourie, P. B., Fielding, K. L., Grant, A. D., Dorman, S. E. & Churchyard, G. J. Nov 29 2012 In : PLoS One. 7, 11, e50173

Research output: Contribution to journalArticle

Sputum
Microscopy
Tuberculosis
microscopy
Biophysics

QuantiFERON-TB gold in-tube implementation for latent tuberculosis diagnosis in a public health clinic: A cost-effectiveness analysis

Shah, M., Miele, K., Choi, H., DiPietro, D., Martins-Evora, M., Marsiglia, V. & Dorman, S. Dec 19 2012 In : BMC Infectious Diseases. 12, 360

Research output: Contribution to journalArticle

Latent Tuberculosis
Gold
Cost-Benefit Analysis
Public Health
Tuberculin Test

Safety and pharmacokinetics of escalating daily doses of the antituberculosis drug rifapentine in healthy volunteers

Dooley, K. E., Bliven-Sizemore, E. E., Weiner, M., Lu, Y., Nuermberger, E. L., Hubbard, W. C., Fuchs, E. J., Melia, M. T., Burman, W. J. & Dorman, S. E. May 2012 In : Clinical Pharmacology and Therapeutics. 91, 5, p. 881-888 8 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Midazolam
Cytochromes
Rifampin
Area Under Curve

Substitution of rifapentine for rifampin during intensive phase treatment of pulmonary tuberculosis: Study 29 of the tuberculosis trials consortium

Dorman, S. E., Goldberg, S., Stout, J. E., Muzanyi, G., Johnson, J. L., Weiner, M., Bozeman, L., Heilig, C. M., Feng, P. J., Moro, R., Narita, M., Nahid, P., Ray, S., Bates, E., Haile, B., Nuermberger, E. L., Vernon, A. & Schluger, N. W. Oct 1 2012 In : Journal of Infectious Diseases. 206, 7, p. 1030-1040 11 p.

Research output: Contribution to journalArticle

Rifampin
Pulmonary Tuberculoses
Tuberculosis
Sputum
Confidence Intervals

The Impact of Expanded Testing for Multidrug Resistant Tuberculosis Using Geontype MTBDRplus in South Africa: An Observational Cohort Study

Hanrahan, C. F., Dorman, S. E., Erasmus, L., Koornhof, H., Coetzee, G. & Golub, J. E. Nov 30 2012 In : PLoS One. 7, 11, e49898

Research output: Contribution to journalArticle

Multidrug-Resistant Tuberculosis
South Africa
Observational Study
Cohort Studies
tuberculosis
2011

Diagnostic accuracy of a urine lipoarabinomannan enzyme-linked immunosorbent assay for screening ambulatory HIV-infected persons for tuberculosis

Gounder, C. R., Kufa, T., Wada, N. I., Mngomezulu, V., Charalambous, S., Hanifa, Y., Fielding, K., Grant, A., Dorman, S., Chaisson, R. E. & Churchyard, G. J. Oct 1 2011 In : Journal of Acquired Immune Deficiency Syndromes. 58, 2, p. 219-223 5 p.

Research output: Contribution to journalArticle

Tuberculosis
Enzyme-Linked Immunosorbent Assay
HIV
Urine
Confidence Intervals

Geographic differences in time to culture conversion in liquid media: Tuberculosis trials Consortium Study 28. Culture conversion is delayed in Africa

Mac Kenzie, W. R., Heilig, C. M., Bozeman, L., Johnson, J. L., Muzanye, G., Dunbar, D., Jost, K. C., Diem, L., Metchock, B., Eisenach, K., Dorman, S. & Goldberg, S. 2011 In : PLoS One. 6, 4, e18358

Research output: Contribution to journalArticle

Supravalvular Aortic Stenosis
Tuberculosis
Birth Certificates
liquids
Acromion