Susan Doris Michaelis


1980 …2019
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Research Output 1980 2019

A humanized yeast system to analyze cleavage of prelamin A by ZMPSTE24

Spear, E., Alford, R. F., Babatz, T. D., Wood, K. M., Mossberg, O. W., Odinammadu, K., Shilagardi, K., Gray, J. J. & Michaelis, S. D., Jan 1 2019, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

Lamin Type A
Aging of materials

Permanently farnesylated prelamin a, progeria, and atherosclerosis

Worman, H. J. & Michaelis, S. D., Jan 1 2018, In : Circulation. 138, 3, p. 283-286 4 p.

Research output: Contribution to journalEditorial


Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum-Associated Degradation

Preston, G. M., Guerriero, C. J., Metzger, M. B., Michaelis, S. D. & Brodsky, J. L., Jan 1 2018, (Accepted/In press) In : Molecular Cell.

Research output: Contribution to journalArticle

Endoplasmic Reticulum-Associated Degradation
Endoplasmic Reticulum

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin a cleavage activity and/or protein stability

Spear, E., Hsu, E. T., Nie, L., Carpenter, E. P., Hrycyna, C. A. & Michaelis, S. D., Jul 1 2018, In : DMM Disease Models and Mechanisms. 11, 7, Y.

Research output: Contribution to journalArticle

Protein Stability
Missense Mutation
Membrane Proteins

Degradation signals for ubiquitin-proteasome dependent cytosolic protein quality control (CytoQC) in yeast

Maurer, M. J., Spear, E., Yu, A. T., Lee, E. J., Shahzad, S. & Michaelis, S. D., Jul 1 2016, In : G3: Genes, Genomes, Genetics. 6, 7, p. 1853-1866 14 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Quality Control
Ubiquitin-Protein Ligases