Stephen Gould

Research output

Research output per year 1986 1995 1996 1998 1999 2000 2002 2022

• 110 Article
• 12 Review article
• 6 Comment/debate
• 4 Chapter
• 3 More
  • 2 Short survey
  • 1 Letter

Research output per year

Research output per year

Search results

• 2022

  A shared, stochastic pathway mediates exosome protein budding along plasma and endosome membranes

  Fordjour, F. K., Guo, C., Ai, Y., Daaboul, G. G. & Gould, S. J., Oct 2022, In: Journal of Biological Chemistry. 298, 10, 102394.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exosomes 100%
  • Endosomes 95%
  • Cell Membrane 61%
  • Plasma 52%
  • Membranes 50%

• Continued Virus-Specific Antibody-Secreting Cell Production, Avidity Maturation and B Cell Evolution in Patients Hospitalized with COVID-19

  Bartlett, M. L., Suwanmanee, S., Peart Akindele, N., Ghimire, S., Chan, A. K. P., Guo, C., Gould, S. J., Cox, A. L. & Griffin, D. E., Apr 2022, In: Viral Immunology. 35, 3, p. 259-272 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Antibody-Producing Cells 100%
  • B-Lymphocytes 59%
  • Viruses 51%
  • Immunoglobulin G 36%
  • Immunoglobulin M 25%

• Degron tagging of BleoR and other antibiotic-resistance genes selects for higher expression of linked transgenes and improved exosome engineering

  Tsai, S. J., Ai, Y., Guo, C. & Gould, S. J., May 1 2022, In: Journal of Biological Chemistry. 298, 5, 101846.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exosomes 100%
  • Transgenes 85%
  • Microbial Drug Resistance 84%
  • Resistance 53%
  • Antimicrobial Agent 51%

• Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research

  Mateescu, B., Jones, J. C., Alexander, R. P., Alsop, E., An, J. Y., Asghari, M., Boomgarden, A., Bouchareychas, L., Cayota, A., Chang, H. C., Charest, A., Chiu, D. T., Coffey, R. J., Das, S., De Hoff, P., deMello, A., D'Souza-Schorey, C., Elashoff, D., Eliato, K. R., Franklin, J. L., & 76 othersGalas, D. J., Gerstein, M. B., Ghiran, I. H., Go, D. B., Gould, S., Grogan, T. R., Higginbotham, J. N., Hladik, F., Huang, T. J., Huo, X., Hutchins, E., Jeppesen, D. K., Jovanovic-Talisman, T., Kim, B. Y. S., Kim, S., Kim, K. M., Kim, Y., Kitchen, R. R., Knouse, V., LaPlante, E. L., Lebrilla, C. B., Lee, L. J., Lennon, K. M., Li, G., Li, F., Li, T., Liu, T., Liu, Z., Maddox, A. L., McCarthy, K., Meechoovet, B., Maniya, N., Meng, Y., Milosavljevic, A., Min, B. H., Morey, A., Ng, M., Nolan, J., De Oliveira Junior, G. P., Paulaitis, M. E., Phu, T. A., Raffai, R. L., Reátegui, E., Roth, M. E., Routenberg, D. A., Rozowsky, J., Rufo, J., Senapati, S., Shachar, S., Sharma, H., Sood, A. K., Stavrakis, S., Stürchler, A., Tewari, M., Tosar, J. P., Tucker-Schwartz, A. K., Turchinovich, A., Valkov, N., Van Keuren-Jensen, K., Vickers, K. C., Vojtech, L., Vreeland, W. N., Wang, C., Wang, K., Wang, Z. Y., Welsh, J. A., Witwer, K. W., Wong, D. T. W., Xia, J., Xie, Y. H., Yang, K., Zaborowski, M. P., Zhang, C., Zhang, Q., Zivkovic, A. M. & Laurent, L. C., Aug 19 2022, In: iScience. 25, 8, 104653.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Communication 100%
  • RNA 92%
  • Industrial Development 91%
  • Theranostic Nanomedicine 88%
  • Technology 87%

• The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation

  Guo, C., Tsai, S. J., Ai, Y., Li, M., Anaya, E., Pekosz, A., Cox, A. & Gould, S. J., Dec 2022, In: Science Advances. 8, 51, eade5085.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Furin 100%
  • Severe Acute Respiratory Syndrome 90%
  • Coronavirus 88%
  • Insertional Mutagenesis 82%
  • Lysosomes 71%
• 2021

  Choice of selectable marker affects recombinant protein expression in cells and exosomes

  Guo, C., Fordjour, F. K., Tsai, S. J., Morrell, J. C. & Gould, S. J., Jul 1 2021, In: Journal of Biological Chemistry. 297, 1, 100838.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exosomes 100%
  • Recombinant Proteins 83%
  • Marker 74%
  • Protein 35%
  • Cell Line 31%

• Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity

  Tsai, S. J., Atai, N. A., Cacciottolo, M., Nice, J., Salehi, A., Guo, C., Sedgwick, A., Kanagavelu, S. & Gould, S. J., Nov 1 2021, In: Journal of Biological Chemistry. 297, 5, 101266.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Exosomes 79%
  • Immunity 55%
  • Messenger RNA 38%
  • Lipid 23%

• Extracellular vesicles derived from cardiosphere-derived cells as a potential antishock therapeutic

  Chance, T. C., Wu, X., Keesee, J. D., Garcia-Marcano, J., Salgado, C. L., Liu, B., Moseley, J. J., Peck, K. A., Borlado, L. R., Atai, N. A., Gould, S. J., Marban, L. S., Cap, A. P., Rathbone, C. R. & Bynum, J. A., Aug 2021, In: Journal of Trauma and Acute Care Surgery. 91, 2, p. S81-S88

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Vesicles 100%
  • Centers for Disease Control and Prevention (U.S.) 31%
  • Hemorrhagic Shock 27%
  • Multiple Trauma 26%
  • Therapeutics 13%

• Lipids | Peroxisomal metabolism

  Gould, S. J., Jul 29 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 1. p. 501-506 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Transport and secretion | Exosomes and microvesicles

  Gould, S. J. & Schaffer, J. E., Jul 29 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 5. p. 455-458 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2019

  Exosomes

  Pegtel, D. M. & Gould, S. J., Jun 20 2019, In: Annual review of biochemistry. 88, p. 487-514 28 p.

  Research output: Contribution to journal › Article › peer-review

  • Exosomes 100%
  • Protein 35%
  • Heterogeneity 26%
  • Quality Control 25%
  • Membranes 25%
  277 Scopus citations

• The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research

  The Extracellular RNA Communication Consortium, Apr 4 2019, In: Cell. 177, 2, p. 231-242 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Communication 100%
  • RNA 76%
  • Technology 71%
  • Extracellular Vesicles 43%
  • Biological Marker 39%
  59 Scopus citations
• 2018

  Advances, challenges, and opportunities in extracellular RNA biology: Insights from the NIH exRNA Strategic Workshop

  Li, K., Rodosthenous, R. S., Kashanchi, F., Gingeras, T., Gould, S. J., Kuo, L. S., Kurre, P., Lee, H., Leonard, J. N., Liu, H., Lombo, T. B., Momma, S., Nolan, J. P., Ochocinska, M. J., Pegtel, D. M., Sadovsky, Y., Sánchez-Madrid, F., Valdes, K. M., Vickers, K. C., Weaver, A. M., & 5 othersWitwer, K. W., Zeng, Y., Das, S., Raffai, R. L. & Howcroft, T. K., Apr 5 2018, In: JCI Insight. 3, 7, e98942.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • RNA 100%
  • Education 90%
  • RNA Transport 31%
  • Transducers 21%
  • Therapeutics 3%
  25 Scopus citations
• 2017

  Cell biology: Organelle formation from scratch

  Hettema, E. H. & Gould, S. J., Feb 9 2017, In: Nature. 542, 7640, p. 174-175 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  8 Scopus citations

• Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model

  Li, L., Piontek, K., Ishida, M., Fausther, M., Dranoff, J. A., Fu, R., Mezey, E., Gould, S. J., Fordjour, F. K., Meltzer, S. J., Sirica, A. E. & Selaru, F. M., Feb 1 2017, In: Hepatology. 65, 2, p. 501-514 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Vesicles 100%
  • Cholangiocarcinoma 97%
  • MicroRNAs 71%
  • Survival 47%
  • Fibroblasts 27%
  62 Scopus citations
• 2016

  Extending gene ontology in the context of extracellular RNA and vesicle communication

  Cheung, K. H., Keerthikumar, S., Roncaglia, P., Subramanian, S. L., Roth, M. E., Samuel, M., Anand, S., Gangoda, L., Gould, S., Alexander, R., Galas, D., Gerstein, M. B., Hill, A. F., Kitchen, R. R., Lötvall, J., Patel, T., Procaccini, D. C., Quesenberry, P., Rozowsky, J., Raffai, R. L., & 8 othersShypitsyna, A., Su, A. I., Théry, C., Vickers, K., Wauben, M. H. M., Mathivanan, S., Milosavljevic, A. & Laurent, L. C., Apr 12 2016, In: Journal of Biomedical Semantics. 7, 1, 19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA 100%
  • Extracellular Vesicles 97%
  • Gene Ontology 95%
  • Genes 79%
  • Ontology 69%
  19 Scopus citations
• 2015

  Meeting report: Discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium

  Laurent, L. C., Abdel-Mageed, A. B., David Adelson, P., Arango, J., Balaj, L., Breakefield, X., Carlson, E., Carter, B. S., Majem, B., Chen, C. C., Cocucci, E., Danielson, K., Courtright, A., Das, S., Elmageed, Z. Y. A., Enderle, D., Ezrin, A., Ferrer, M., Freedman, J., Galas, D., & 30 othersGandhi, R., Huentelman, M. J., Van Keuren-Jensen, K., Kalani, Y., Kim, Y., Krichevsky, A. M., Lai, C., Lal-Nag, M., Laurent, C. D., Leonardo, T., Li, F., Malenica, I., Mondal, D., Nejad, P., Patel, T., Raffai, R. L., Rubio, R., Skog, J., Spetzler, R., Sun, J., Tanriverdi, K., Vickers, K., Wang, L., Wang, Y., Wei, Z., Weiner, H. L., Wong, D., Yan, I. K., Yeri, A. & Gould, S., 2015, In: Journal of Extracellular Vesicles. 4, 1, 26533.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Communication 100%
  • RNA 92%
  • Ribonucleoproteins 32%
  • Extracellular Vesicles 31%
  • National Institutes of Health (U.S.) 27%
  40 Scopus citations
• 2013

  As we wait: Coping with an imperfect nomenclature for extracellular vesicles

  Gould, S. J. & Raposo, G., 2013, In: Journal of Extracellular Vesicles. 2, 1, 20389.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  506 Scopus citations

• Exosomes and Microvesicles

  Gould, S. J., Feb 15 2013, Encyclopedia of Biological Chemistry: Second Edition. Elsevier Inc., p. 262-264 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Exosomes 100%
  • Protein 35%
  • Plasma 34%
  • Cell Membrane 22%
  • Multivesicular Bodies 21%
  1 Scopus citations

• Peroxisomal Metabolism

  Gould, S. J., Feb 15 2013, Encyclopedia of Biological Chemistry: Second Edition. Elsevier Inc., p. 413-417 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Peroxisomes 100%
  • Fatty Acids 89%
  • Fatty Acid 84%
  • Pharmacological Metabolism 81%
  • Ether 29%

• The cis-acting signals that target proteins to exosomes and microvesicles

  Yang, J. M. & Gould, S. J., Feb 2013, In: Biochemical Society transactions. 41, 1, p. 277-282 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Exosomes 100%
  • Protein 35%
  • Proteins 31%
  • Carbohydrate Acid 25%
  • Cell Polarity 20%
  56 Scopus citations
• 2012

  HIV Pol inhibits HIV budding and mediates the severe budding defect of Gag-Pol

  Gan, X. & Gould, S. J., Jan 3 2012, In: PloS one. 7, 1, e29421.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • exosomes 100%
  • HIV 95%
  • gag Gene Products 93%
  • viruses 89%
  • polyproteins 87%
  10 Scopus citations
• 2011

  Biogenesis of the posterior pole is mediated by the exosome/microvesicle protein-sorting pathway

  Shen, B., Fang, Y., Wu, N. & Gould, S. J., Dec 23 2011, In: Journal of Biological Chemistry. 286, 51, p. 44162-44176 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exosomes 100%
  • Protein Transport 94%
  • Protein 35%
  • Retroviridae 30%
  • Oligomerization 29%
  49 Scopus citations

• Identification of an inhibitory budding signal that blocks the release of HIV particles and exosome/microvesicle proteins

  Gan, X. & Gould, S. J., Mar 15 2011, In: Molecular biology of the cell. 22, 6, p. 817-830 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exosomes 100%
  • Virion 81%
  • HIV 58%
  • Endosomal Sorting Complexes Required for Transport 43%
  • Virus Release 38%
  49 Scopus citations

• Protein targeting to exosomes/microvesicles by plasma membrane anchors

  Shen, B., Wu, N., Yang, M. & Gould, S. J., Apr 22 2011, In: Journal of Biological Chemistry. 286, 16, p. 14383-14395 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exosomes 100%
  • Cell Membrane 61%
  • Myristoylation 56%
  • Plasma 52%
  • Phosphatidylinositol 40%
  177 Scopus citations
• 2009

  Oleate β-oxidation in yeast involves thioesterase but not Yor180c protein that is not a dienoyl-CoA isomerase

  Ntamack, A. G., Karpichev, I. V., Gould, S. J., Small, G. M. & Schulz, H., May 2009, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1791, 5, p. 371-378 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Isomerases 100%
  • Coenzyme A 86%
  • Oleic Acid 80%
  • Yeasts 56%
  • Palmitic Acid 52%
  5 Scopus citations
• 2007

  Higher-order oligomerization targets plasma membrane proteins and HIV Gag to exosomes

  Fang, Y., Wu, N., Gan, X., Yan, W., Morrell, J. C. & Gould, S. J., Mar 2007, In: PLoS biology. 5, 6, p. 1267-1283 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • exosomes 100%
  • oligomerization 87%
  • Exosomes 81%
  • Oligomerization 70%
  • blood proteins 63%
  245 Scopus citations
• 2006

  Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane

  Booth, A. M., Fang, Y., Fallon, J. K., Yang, J. M., Hildreth, J. E. K., Gould, S. J., Sandefur, S. & Varthakavi, V., Mar 13 2006, In: Journal of Cell Biology. 172, 6, p. 923-935 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exosomes 100%
  • Endosomes 95%
  • Cell Membrane 61%
  • HIV 58%
  • T-Lymphocytes 52%
  377 Scopus citations
• 2005

  Alternative splicing suggests extended function of PEX26 in peroxisome biogenesis

  Weller, S., Cajigas, I., Morrell, J., Obie, C., Steel, G., Gould, S. J. & Valle, D., Jun 2005, In: American journal of human genetics. 76, 6, p. 987-1007 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peroxisomes 100%
  • Alternative Splicing 85%
  • Peroxisome biogenesis disorders 46%
  • Membrane Proteins 43%
  • Proteins 29%
  38 Scopus citations

• Assay and functional analysis of dynamin-like protein 1 in peroxisome division

  Schrader, M. & Gould, S. J., 2005, In: Methods in enzymology. 404, p. 586-597 12 p., 51.

  Research output: Contribution to journal › Review article › peer-review

  • Dynamins 100%
  • Peroxisomes 95%
  • Protein 31%
  • Proteins 27%
  • Mammalian Cell 25%
  3 Scopus citations

• Detecting patterns of protein distribution and gene expression in silico.

  Bassett, D., Morrell, J. C., Gatto, G. J., Bai, J., Geisbrecht, B. V., Hieter, P. & Gould, S. J., Jan 11 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 2, p. 516 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Erratum: Molecular characterization of Saccharomyces cerevisiae Δ³,Δ²-enoyl-CoA isomerase (The Journal of Biological Chemistry (1998) 273 (33184-33191))

  Geisbrecht, B. V., Zhu, D., Schulz, K., Nau, K., Morrell, J. C., Geraghty, M., Schulz, H., Erdmann, R. & Gould, S. J., Apr 1 2005, In: Journal of Biological Chemistry. 280, 13, p. 13203 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Erratum (Retracted Article): Detecting patterns of protein distribution and gene expression in silico (Proceedings of the National Academy of Sciences of the United States of America (March 16, 1999) 96:6 (2937-2942))

  Geraghty, M. T., Bassett, D., Morrell, J. C., Gatto, G. J., Bai, J., Geisbrecht, B. V., Hieter, P. & Gould, S. J., Jan 11 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 2, p. 516 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  1 Scopus citations
• 2004

  Erratum: Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy-acid oxidases (The Journal of Biological Chemistry (2000) 275 (12590-12597))

  Jones, J. M., Morrell, J. C. & Gould, S. J., Aug 13 2004, In: Journal of Biological Chemistry. 279, 33, p. 35122 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  2 Scopus citations

• PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins

  Jones, J. M., Morrell, J. C. & Gould, S. J., Jan 2004, In: Journal of Cell Biology. 164, 1, p. 57-67 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Membrane Proteins 100%
  • Cytosol 16%
  • Cytoplasm 14%
  • Proteins 6%
  175 Scopus citations

• PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins

  Fang, Y., Morrell, J. C., Jones, J. M. & Gould, S. J., Mar 15 2004, In: Journal of Cell Biology. 164, 6, p. 863-875 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peroxisomes 100%
  • Membrane Proteins 65%
  • Membranes 18%
  • Organelles 15%
  • Cytoplasm 12%
  154 Scopus citations

• The evolution of alloimmunity and the genesis of adaptive immunity

  Gould, S. J., Hildreth, J. E. K. & Booth, A. M., Dec 2004, In: Quarterly Review of Biology. 79, 4, p. 359-382 24 p.

  Research output: Contribution to journal › Review article › peer-review

  • Histocompatibility 100%
  • adaptive immunity 95%
  • Adaptive Immunity 81%
  • Retroviridae 47%
  • pathogens 47%
  7 Scopus citations
• 2003

  Correlating structure and affinity for PEX5:PTS1 complexes

  Gatto, G. J., Maynard, E. L., Guerrerio, A. L., Geisbrecht, B. V., Gould, S. J. & Berg, J. M., Feb 18 2003, In: Biochemistry. 42, 6, p. 1660-1666 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Peroxisomal Targeting Signals 100%
  • Tripeptide 65%
  • Pentapeptide 36%
  • seryl-lysyl-leucine 35%
  • carboxyl radical 29%
  39 Scopus citations

• Evidence That HIV Budding in Primary Macrophages Occurs through the Exosome Release Pathway

  Nguyen, D. G., Booth, A., Gould, S. J. & Hildreth, J. E. K., Dec 26 2003, In: Journal of Biological Chemistry. 278, 52, p. 52347-52354 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Virus Release 100%
  • Exosomes 86%
  • Macrophages 51%
  • Lipid 50%
  • HIV 50%
  249 Scopus citations

• Peroxisome Biogenesis Disorders

  Weller, S., Gould, S. J. & Valle, D., 2003, In: Annual Review of Genomics and Human Genetics. 4, p. 165-211 47 p.

  Research output: Contribution to journal › Review article › peer-review

  • Peroxisome biogenesis disorders 100%
  • Peroxisomes 36%
  • Phenotype 34%
  • Homeostasis 20%
  • Genes 11%
  147 Scopus citations

• PEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12

  Harper, C. C., Berg, J. M. & Gould, S. J., Mar 7 2003, In: Journal of Biological Chemistry. 278, 10, p. 7897-7901 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peroxins 100%
  • Peroxisomes 36%
  • carboxyl radical 25%
  • Peroxisomal Targeting Signals 24%
  • Protein 23%
  25 Scopus citations

• The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11

  Li, X. & Gould, S. J., May 9 2003, In: Journal of Biological Chemistry. 278, 19, p. 17012-17020 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dynamins 100%
  • Peroxisomes 95%
  • GTP Phosphohydrolases 85%
  • Protein 31%
  • Reaction Stoichiometry 30%
  174 Scopus citations

• The Trojan exosome hypothesis

  Gould, S. J., Booth, A. M. & Hildreth, J. E. K., Sep 16 2003, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 19, p. 10592-10597 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Exosomes 100%
  • Retroviridae 91%
  • Vaccines 31%
  • Histocompatibility Antigens Class II 23%
  • Adaptive Immunity 21%
  417 Scopus citations
• 2002

  Erratum: Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5 (Nature Structural Biology (2002) 7 (1091-1095))

  Gatto, G. J., Geisbrecht, B. V., Gould, S. J. & Berg, J. M., Oct 2002, In: Nature Structural Biology. 9, 10, p. 788 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Functional characterization of Δ³,Δ²-enoyl-CoA isomerases from rat liver

  Zhang, D., Yu, W., Geisbrecht, B. V., Gould, S. J., Sprecher, H. & Schulz, H., Mar 15 2002, In: Journal of Biological Chemistry. 277, 11, p. 9127-9132 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dodecenoyl-CoA Isomerase 100%
  • 2-Enoyl-CoA 95%
  • Isomerization 40%
  • Liver 26%
  • Multifunctional Enzymes 15%
  42 Scopus citations

• Peroxisomal membrane protein import does not require Pex17p

  Harper, C. C., South, S. T., Michael McCaffery, J. & Gould, S. J., May 10 2002, In: Journal of Biological Chemistry. 277, 19, p. 16498-16504 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Membrane Proteins 100%
  • Protein 49%
  • Pichia 15%
  • Peroxisomes 15%
  • Protein Stability 14%
  13 Scopus citations

• Peroxisomal-protein import: Is it really that complex?

  Gould, S. J. & Collins, C. S., 2002, In: Nature Reviews Molecular Cell Biology. 3, 5, p. 382-389 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Peroxisomes 100%
  • Enzymes 64%
  • Membranes 47%
  • Proteins 43%
  • Organelles 37%
  88 Scopus citations

• PEX11 promotes peroxisome division independently of peroxisome metabolism

  Li, X. & Gould, S. J., Feb 18 2002, In: Journal of Cell Biology. 156, 4, p. 643-651 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peroxisomes 100%
  • Fatty Acids 19%
  • Ether 12%
  • Proteins 12%
  • Metabolic Networks and Pathways 11%
  110 Scopus citations

• PEX11α is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation

  Li, X., Baumgart, E., Dong, G. X., Morrell, J. C., Jimenez-Sanchez, G., Valle, D., Smith, K. D. & Gould, S. J., Dec 2002, In: Molecular and cellular biology. 22, 23, p. 8226-8240 15 p.

  Research output: Contribution to journal › Article › peer-review

  • 4-phenylbutyric acid 100%
  • PPAR alpha 81%
  • Peroxisomes 80%
  • Genes 7%
  • Eukaryota 6%
  116 Scopus citations

• PEX11β deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function

  Li, X., Baumgart, E., Morrell, J. C., Jimenez-Sanchez, G., Valle, D. & Gould, S. J., 2002, In: Molecular and cellular biology. 22, 12, p. 4358-4365 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peroxisomes 80%
  • Muscle Hypotonia 19%
  • Phenotype 9%
  • Ether 8%
  • Nervous System Diseases 7%
  126 Scopus citations