Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

V(D)J Recombination Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences
Genetic Recombination Medicine & Life Sciences
VDJ Recombinases Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Genes Medicine & Life Sciences
Antigen Receptors Medicine & Life Sciences
DNA Medicine & Life Sciences

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Research Output 1978 2018

Smoothened signaling in the mouse osteoblastoid lineage is required for efficient b lymphopoiesis

Lu, W., Dordai, D., Huso, D. & Desiderio, S. Jan 18 2018 In : Blood. 131, 3, p. 323-327 5 p.

Research output: Contribution to journalArticle

Lymphopoiesis
Hedgehogs
Bone Marrow
Stromal Cells
Osteoblasts
VDJ Recombinases
RAG-1 Genes
Genetic Recombination
Catalytic Domain
DNA

Pumping the breaks on B cell development

Desiderio, S. 2016 In : Journal of Experimental Medicine. 213, 2, p. 140 1 p.

Research output: Contribution to journalArticle

Macular Degeneration
Innate Immunity
B-Lymphocytes
Interleukin-33

An autoregulatory mechanism imposes allosteric control on the V(D)J recombinase by histone H3 methylation

Lu, C., Ward, A., Bettridge, J., Liu, Y. & Desiderio, S. Jan 6 2015 In : Cell Reports. 10, 1, p. 29-38 10 p.

Research output: Contribution to journalArticle

VDJ Recombinases
DNA Cleavage
Methylation
Histones
Genetic Recombination

53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation

Rybanska-Spaeder, I., Reynolds, T. L., Chou, J., Prakash, M., Jefferson, T., Huso, D. L., Desiderio, S. & Franco, S. 2013 In : Molecular Cancer Research. 11, 10, p. 1223-1234 12 p.

Research output: Contribution to journalArticle

Ataxia Telangiectasia
Radiation
Joints
Thymocytes
VDJ Recombinases