Stephen B Baylin

Professor

1963 …2019
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Neoplasms Medicine & Life Sciences
Methylation Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
DNA Methylation Medicine & Life Sciences
Genes Medicine & Life Sciences
CpG Islands Medicine & Life Sciences
DNA Medicine & Life Sciences
Calcitonin Medicine & Life Sciences

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Research Output 1963 2019

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf V600E -Induced Tumorigenesis

Tao, Y., Kang, B., Petkovich, D. A., Bhandari, Y. R., In, J., Stein-O'Brien, G., Kong, X., Xie, W., Zachos, N., Maegawa, S., Vaidya, H., Brown, S., Chiu Yen, R. W., Shao, X., Thakor, J., Lu, Z., Cai, Y., Zhang, Y., Mallona, I., Peinado, M. A. & 6 others, Zahnow, C. A., Ahuja, N., Fertig, E., Issa, J. P., Baylin, S. B. & Easwaran, H., Feb 11 2019, In : Cancer cell. 35, 2, p. 315-328.e6

Research output: Contribution to journalArticle

Epigenomics
Organoids
Colon
Carcinogenesis
Clustered Regularly Interspaced Short Palindromic Repeats

Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties

Kong, X., Chen, J., Xie, W., Brown, S. M., Cai, Y., Wu, K., Fan, D., Nie, Y., Yegnasubramanian, S., Tiedemann, R. L., Tao, Y., Yen, R-W., Topper, M. J., Zahnow, C., Easwaran, H., Rothbart, S. B., Xia, L. & Baylin, S. B., Apr 15 2019, In : Cancer cell. 35, 4, p. 633-648.e7

Research output: Contribution to journalArticle

DNA Methylation
Colonic Neoplasms
Colorectal Neoplasms
Ubiquitin-Protein Ligases
Tumor Suppressor Genes

DFMO and 5-azacytidine increase M1 macrophages in the tumor microenvironment of murine ovarian cancer

Travers, M., Brown, S. M., Dunworth, M., Holbert, C. E., Wiehagen, K. R., Bachman, K. E., Foley, J. R., Stone, M. L., Baylin, S. B., Casero, R. A. & Zahnow, C., Jan 1 2019, In : Cancer Research. 79, 13, p. 3445-3454 10 p.

Research output: Contribution to journalArticle

Eflornithine
Azacitidine
Tumor Microenvironment
Ovarian Neoplasms
Macrophages

The emerging role of epigenetic therapeutics in immuno-oncology

Topper, M. J., Vaz, M., Marrone, K. A., Brahmer, J. R. & Baylin, S. B., Jan 1 2019, (Accepted/In press) In : Nature Reviews Clinical Oncology.

Research output: Contribution to journalReview article

Epigenomics
Immunotherapy
Genetic Epigenesis
Therapeutics
Neoplasms

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 690-705.e9

Research output: Contribution to journalArticle

Breast Neoplasms
Atlases
Long Noncoding RNA
Decision Trees
Genome