Sinisa Urban


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Research Output 1998 2016

A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP

Hwang, J., Ribbens, D., Raychaudhuri, S., Cairns, L., Gu, H., Frost, A., Urban, S. & Espenshade, P. J., 2016, (Accepted/In press) In : EMBO Journal.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Proteins
Peptide Hydrolases
Ubiquitin-Protein Ligases

A guide to the rhomboid protein superfamily in development and disease

Urban, S., Dec 1 2016, In : Seminars in Cell and Developmental Biology. 60, p. 1-4 4 p.

Research output: Contribution to journalReview article

Parasitic Diseases
Serine Proteases
Hand Strength
Protein Transport
Computer Systems
Peptide Hydrolases
Enzyme kinetics

Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis

Cho, S., Dickey, S. W. & Urban, S., Feb 4 2016, In : Molecular Cell. 61, 3, p. 329-340 12 p.

Research output: Contribution to journalArticle

Drug Design
Peptide Hydrolases

Nicastrin guards Alzheimer's gate

Urban, S., Feb 2 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 5, p. 1112-1114 3 p.

Research output: Contribution to journalArticle

Amyloid Precursor Protein Secretases
Membrane Glycoproteins