1993 …2020

Research output per year

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12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma

Mabalirajan, U., Rehman, R., Ahmad, T., Kumar, S., Leishangthem, G. D., Singh, S., Dinda, A. K., Biswal, S., Agrawal, A. & Ghosh, B., Apr 9 2013, In : Scientific reports. 3, 1540.

Research output: Contribution to journalArticle

Acrolein causes inhibitor κb-independent decreases in nuclear factor κB activation in human lung adenocarcinoma (A549) cells

Horton, N. D., Biswal, S. S., Corrigan, L. L., Bratta, J. & Kehrer, J. P., Apr 2 1999, In : Journal of Biological Chemistry. 274, 14, p. 9200-9206 7 p.

Research output: Contribution to journalArticle

Acrolein causes transcriptional induction of phase II genes by activation of Nrf2 in human lung type II epithelial (A549) cells

Tirumalai, R., Rajesh Kumar, T., Mai, K. H. & Biswal, S., Jun 7 2002, In : Toxicology Letters. 132, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: A comprehensive transcriptional response

Tian, J., Ishibashi, K., Ishibashi, K., Reiser, K., Grebe, R., Biswal, S., Gehlbach, P. & Handa, J. T., Aug 16 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 33, p. 11846-11851 6 p.

Research output: Contribution to journalArticle

Air pollution-derived particulate matter dysregulates hepatic Krebs cycle, glucose and lipid metabolism in mice

Reyes-Caballero, H., Rao, X., Sun, Q., Warmoes, M. O., Penghui, L., Sussan, T. E., Park, B., Fan, T. W. M., Maiseyeu, A., Rajagopalan, S., Girnun, G. D. & Biswal, S., Dec 1 2019, In : Scientific reports. 9, 1, 17423.

Research output: Contribution to journalArticle

Open Access

Alpha2B-adrenergic receptor overexpression in the brain potentiate air pollution-induced behavior and blood pressure changes

Rao, X., Asico, L. D., Zanos, P., Mahabeleshwar, G. H., Gangwar, R. S., Xia, C., Duan, L., Cisse, Y. M., Rengasamy, P., Jose, P. A., Gould, T. D., Nelson, R., Biswal, S., Chen, L. C., Zhong, J. & Rajagopalan, S., Jan 1 2019, In : Toxicological Sciences. 169, 1, p. 95-107 13 p.

Research output: Contribution to journalArticle

An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma

An, S. S., Mitzner, W., Tang, W. Y., Ahn, K., Yoon, A. R., Huang, J., Kilic, O., Yong, H. M., Fahey, J. W., Kumar, S., Biswal, S., Holgate, S. T., Panettieri, R. A., Solway, J. & Liggett, S. B., Jul 1 2016, In : Journal of Allergy and Clinical Immunology. 138, 1, p. 294-297.e4

Research output: Contribution to journalArticle

A novel cinnamate derivative attenuates asthma features and reduces bronchial epithelial injury in mouse model

Kumar, S., Mabalirajan, U., Rehman, R., Singh, B. K., Parmar, V. S., Prasad, A. K., Biswal, S. & Ghosh, B., Jan 1 2013, In : International Immunopharmacology. 15, 1, p. 150-159 10 p.

Research output: Contribution to journalArticle

A relationship between 5-lipoxygenase-activating protein and bcl-x(L) expression in murine pro-B lymphocytic FL5.12 cells

Datta, K., Biswal, S. S., Xu, J., Towndrow, K. M., Feng, X. & Kehrer, J. P., Oct 23 1998, In : Journal of Biological Chemistry. 273, 43, p. 28163-28169 7 p.

Research output: Contribution to journalArticle

Arylalkyl ketones, benzophenones, desoxybenzoins and chalcones inhibit TNF-α induced expression of ICAM-1: Structure-activity analysis

Kumar, S., Reddy L, C. S., Kumar, Y., Kumar, A., Singh, B. K., Kumar, V., Malhotra, S., Pandey, M. K., Jain, R., Thimmulappa, R., Sharma, S. K., Prasad, A. K., Biswal, S., Van Der Eycken, E., Depass, A. L., Malhotra, S. V., Ghosh, B. & Parmar, V. S., May 2012, In : Archiv der Pharmazie. 345, 5, p. 368-377 10 p.

Research output: Contribution to journalArticle

A search for genes that may confer divergent morphology and function in the carotid body between two strains of mice

Balbir, A., Lee, H., Okumura, M., Biswal, S., Fitzgerald, R. S. & Shirahata, M., Mar 1 2007, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 292, 3, p. L704-L715

Research output: Contribution to journalArticle

Association between bcl-xL and 5-lipoxygenase activating protein (FLAP) levels in IL-3-dependent FL5.12 cells

Biswal, S. S., Datta, K. & Kehrer, J. P., Mar 7 2001, In : Toxicology. 160, 1-3, p. 97-103 7 p.

Research output: Contribution to journalArticle

Association Between E-Cigarette Use and Chronic Obstructive Pulmonary Disease by Smoking Status: Behavioral Risk Factor Surveillance System 2016 and 2017

Osei, A. D., Mirbolouk, M., Orimoloye, O. A., Dzaye, O., Uddin, S. M. I., Benjamin, E. J., Hall, M. E., DeFilippis, A. P., Bhatnagar, A., Biswal, S. S. & Blaha, M. J., Mar 2020, In : American journal of preventive medicine. 58, 3, p. 336-342 7 p.

Research output: Contribution to journalArticle

Calreticulin transacetylase catalyzed modification of the TNF-α mediated pathway in the human peripheral blood mononuclear cells by polyphenolic acetates

Singh, U., Kumar, A., Sinha, R., Manral, S., Arora, S., Ram, S., Mishra, R. K., Gupta, P., Bansal, S. K., Prasad, A. K., Biswal, S., Parmar, V. S. & Raj, H. G., May 1 2010, In : Chemico-Biological Interactions. 185, 3, p. 263-270 8 p.

Research output: Contribution to journalArticle

Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia

Wang, B., Cao, W., Biswal, S. & Doré, S., Sep 1 2011, In : Stroke. 42, 9, p. 2605-2610 6 p.

Research output: Contribution to journalArticle

Cell stiffness, contractile stress and the role of extracellular matrix

An, S. S., Kim, J., Ahn, K., Trepat, X., Drake, K. J., Kumar, S., Ling, G., Purington, C., Rangasamy, T., Kensler, T. W., Mitzner, W., Fredberg, J. J. & Biswal, S., May 15 2009, In : Biochemical and Biophysical Research Communications. 382, 4, p. 697-703 7 p.

Research output: Contribution to journalArticle

Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells

Biswal, S. S., Datta, K., Acquaah-Mensah, G. K. & Kehrer, J. P., Nov 23 2000, In : Toxicology. 154, 1-3, p. 45-53 9 p.

Research output: Contribution to journalArticle

Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice

Fujihara, M., Nagai, N., Sussan, T. E., Biswal, S. & Handa, J. T., Sep 1 2008, In : PloS one. 3, 9, e3119.

Research output: Contribution to journalArticle

Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression

Rangasamy, T., Misra, V., Zhen, L., Tankersley, C. G., Tuder, R. M. & Biswal, S., Jun 1 2009, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 296, 6, p. L888-L900

Research output: Contribution to journalArticle

Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and Age-related Macular Degeneration

Cano, M., Thimmalappula, R., Fujihara, M., Nagai, N., Sporn, M., Wang, A. L., Neufeld, A. H., Biswal, S. & Handa, J. T., Mar 1 2010, In : Vision Research. 50, 7, p. 652-664 13 p.

Research output: Contribution to journalArticle

Cohort for Tuberculosis Research by the Indo-US Medical Partnership (CTRIUMPH): Protocol for a multicentric prospective observational study

Gupte, A., Padmapriyadarsini, C., Mave, V., Kadam, D., Suryavanshi, N., Shivakumar, S. V. B. Y., Kohli, R., Gupte, N., Thiruvengadam, K., Kagal, A., Meshram, S., Bharadwaj, R., Khadse, S., Ramachandran, G., Hanna, L. E., Pradhan, N., Gomathy, N. S., DeLuca, A., Gupta, A., Swaminathan, S. & 73 others, Kinikar, A., Raja, A., Nagraj, A., Anand Kumar, B., More, A., Gaikwad, A., Nangude, A., Balaji, S., Thomas, B., Joseph, B., Bharath, T. K., Brindha, B., Dowdy, D., Pole, D., Devanathan, A., Devi Sangamithrai, M., Jain, D., Dolla, C. K., Smit, G., Gangadarsharma, R., Chaugule, H., Koli, H., Hemanthkumar, Jeeva, J., Elf, J., Golub, J., Chandane, J., Savita, K., Kannan, M., Karthikesh, M., Karunakaran, S., Dooley, K., Murali, L., Lavanya, M., Madasamy, S., Mageshkumar, M., Mangaiyarkarasi, S., Gujare, M., Manoharan, S., Michel Premkumar, M., Munivardhan, P., Murugesan, S., Gomathy, N. S., Nagaraj, Ponnuraja, C., Premkumar, N., Lokhande, R., Rajkumar, S., Ranganathan, K., Rani, S., Madewar, R., Bollinger, R., Warlick, R., Shivakoti, R., Javanjal, S., Sathyamurthi, P., Pawar, S., Hande, S., Muley, S., Sali, S., Shubhapriya, K., Biswal, S., Silambu Chelvi, K., Nimkar, S., Selvaraj, S., Salvi, S., Raskar, S., Devi, U., Kulkarni, V., Hulyalkar, V., Tayawade, V., Bansode, V. & Daware, Y., Jan 1 2016, In : BMJ open. 6, 2, e010542.

Research output: Contribution to journalArticle

Compartmentalization of anti-oxidant and anti-inflammatory gene expression in current and former smokers with COPD

Sidhaye, V. K., Holbrook, J. T., Burke, A., Sudini, K. R., Sethi, S., Criner, G. J., Fahey, J. W., Berenson, C. S., Jacobs, M. R., Thimmulappa, R. K., Wise, R. A. & Biswal, S., Aug 20 2019, In : Respiratory research. 20, 1, 190.

Research output: Contribution to journalArticle

Open Access

Conditional deletion of Nrf2 in airway epithelium exacerbates acute lung injury and impairs the resolution of inflammation

Reddy, N. M., Potteti, H. R., Mariani, T. J., Biswall, S. & Reddy, S. P., Dec 1 2011, In : American journal of respiratory cell and molecular biology. 45, 6, p. 1161-1168 8 p.

Research output: Contribution to journalArticle

Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1

Malhotra, D., Thimmulappa, R., Navas-Acien, A., Sandford, A., Elliott, M., Singh, A., Chen, L., Zhuang, X., Hogg, J., Pare, P., Tuder, R. M. & Biswal, S., Sep 15 2008, In : American journal of respiratory and critical care medicine. 178, 6, p. 592-604 13 p.

Research output: Contribution to journalArticle

Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress

Mercado, N., Thimmulappa, R., Thomas, C. M. R., Fenwick, P. S., Chana, K. K., Donnelly, L. E., Biswal, S., Ito, K. & Barnes, P. J., Mar 11 2011, In : Biochemical and Biophysical Research Communications. 406, 2, p. 292-298 7 p.

Research output: Contribution to journalArticle

Deficiency in Nrf2 GSH signaling impairs type II cell growth and enhances sensitivity to oxidants

Reddy, N. M., Kleeberger, S. R., Cho, H. Y., Yamamoto, M., Kensler, T. W., Biswal, S. & Reddy, S. P., Jul 2007, In : American journal of respiratory cell and molecular biology. 37, 1, p. 3-8 6 p.

Research output: Contribution to journalArticle

Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation

Blake, D. J., Singh, A., Kombairaju, P., Malhotra, D., Mariani, T. J., Tuder, R. M., Gabrielson, E. & Biswal, S., May 1 2010, In : American journal of respiratory cell and molecular biology. 42, 5, p. 524-536 13 p.

Research output: Contribution to journalArticle

Deletion of Nrf2 enhances susceptibility to eosinophilic sinonasal inflammation in a murine model of rhinosinusitis

London, N. R., Tharakan, A., Mendiola, M., Sussan, T. E., Chen, M., Dobzanski, A., Lane, A. P., Sidhaye, V., Biswal, S. & Ramanathan, M., Jan 1 2018, (Accepted/In press) In : International Forum of Allergy and Rhinology.

Research output: Contribution to journalArticle

Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients

Malhotra, D., Thimmulappa, R. K., Mercado, N., Ito, K., Kombairaju, P., Kumar, S., Ma, J., Feller-Kopman, D., Wise, R., Barnes, P. & Biswal, S., Nov 1 2011, In : Journal of Clinical Investigation. 121, 11, p. 4289-4302 14 p.

Research output: Contribution to journalArticle

De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer

Singh, A., Ruiz, C., Bhalla, K., Haley, J. A., Li, Q. K., Acquaah-Mensah, G., Montal, E., Sudini, K. R., Skoulidis, F., Wistuba, I. I., Papadimitrakopoulou, V., Heymach, J. V., Boros, L. G., Gabrielson, E., Carretero, J., Wong, K. K., Haley, J. D., Biswal, S. & Girnun, G. D., Dec 1 2018, In : FASEB Journal. 32, 12, p. 7018-7027 10 p.

Research output: Contribution to journalArticle

Design, synthesis and evaluation of novel PEGylated curcumin analogs as potent Nrf2 activators in human bronchial epithelial cells

Pandey, M. K., Kumar, S., Thimmulappa, R. K., Parmar, V. S., Biswal, S. & Watterson, A. C., May 18 2011, In : European Journal of Pharmaceutical Sciences. 43, 1-2, p. 16-24 9 p.

Research output: Contribution to journalArticle

Dibenzoylmethane activates Nrf2-dependent detoxification pathway and inhibits benzo(a)pyrene induced DNA adducts in lungs

Thimmulappa, R. K., Rangasamy, T., Alam, J. & Biswal, S., Sep 1 2008, In : Medicinal Chemistry. 4, 5, p. 473-481 9 p.

Research output: Contribution to journalArticle

Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice

Sussan, T. E., Jun, J., Thimmulappa, R., Bedja, D., Antero, M., Gabrielson, K. L., Polotsky, V. Y. & Biswal, S., Nov 21 2008, In : PloS one. 3, 11, e3791.

Research output: Contribution to journalArticle

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

Rangasamy, T., Guo, J., Mitzner, W. A., Roman, J., Singh, A., Fryer, A. D., Yamamoto, M., Kensler, T. W., Tuder, R. M., Georas, S. N. & Biswal, S., Jul 4 2005, In : Journal of Experimental Medicine. 202, 1, p. 47-59 13 p.

Research output: Contribution to journalArticle

Disruption of the transcription factor Nrf2 promotes pro-oxidative dendritic cells that stimulate Th2-like immunoresponsiveness upon activation by ambient particulate matter

Williams, M. A., Rangasamy, T., Bauer, S. M., Killedar, S., Karp, M., Kensler, T. W., Yamamoto, M., Breysse, P., Biswal, S. & Georas, S. N., Oct 1 2008, In : Journal of Immunology. 181, 7, p. 4545-4559 15 p.

Research output: Contribution to journalArticle

Open Access

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer

Singh, A., Misra, V., Thimmulappa, R. K., Lee, H., Ames, S., Hoque, M. O., Herman, J. G., Baylin, S. B., Sidransky, D., Gabrielson, E., Brock, M. V. & Biswal, S., Oct 2006, In : PLoS medicine. 3, 10, p. 1865-1876 12 p.

Research output: Contribution to journalArticle

Effect of diabetic serum factor on polymorphonuclear leucocyte membrane hydrophobicity and particle internalisation

Biswas, S., Bhelwa, A., Itoop, A., Biswal, S. & Nath, N., Sep 1 1994, In : Indian Journal of Clinical Biochemistry. 9, 1, p. 9-12 4 p.

Research output: Contribution to journalArticle

Effects of leptin deficiency on postnatal lung development in mice

Huang, K., Rabold, R., Abston, E., Schofield, B., Misra, V., Galdzicka, E., Lee, H., Biswal, S., Mitzner, W. & Tankersley, C. G., Jul 2008, In : Journal of applied physiology. 105, 1, p. 249-259 11 p.

Research output: Contribution to journalArticle

Electronic cigarette use behaviors and motivations among smokers and non-smokers

Sussan, T. E., Shahzad, F. G., Tabassum, E., Cohen, J. E., Wise, R. A., Blaha, M., Holbrook, J. T. & Biswal, S., Sep 8 2017, In : BMC Public Health. 17, 1, 686.

Research output: Contribution to journalArticle

Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis

Kong, X., Thimmulappa, R., Craciun, F., Harvey, C., Singh, A., Kombairaju, P., Reddy, S. P., Remick, D. & Biswal, S., Oct 15 2011, In : American journal of respiratory and critical care medicine. 184, 8, p. 928-938 11 p.

Research output: Contribution to journalArticle

Ethanol sensitivity: A central role for CREB transcription regulation in the cerebellum

Acquaah-Mensah, G. K., Misra, V. & Biswal, S., Dec 5 2006, In : BMC genomics. 7, 308.

Research output: Contribution to journalArticle

Ethyl 3′,4′,5′-trimethoxythionocinnamate modulates NF-κB and Nrf2 transcription factors

Kumar, S., Singh, B. K., Prasad, A. K., Parmar, V. S., Biswal, S. & Ghosh, B., Jan 30 2013, In : European Journal of Pharmacology. 700, 1-3, p. 32-41 10 p.

Research output: Contribution to journalArticle

Experimental therapeutics of Nrf2 as a target for prevention of bacterial exacerbations in COPD

Biswal, S., Thimmulappa, R. K. & Harvey, C. J., May 1 2012, In : Proceedings of the American Thoracic Society. 9, 2, p. 47-51 5 p.

Research output: Contribution to journalArticle

Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model

Sussan, T. E., Gajghate, S., Thimmulappa, R. K., Ma, J., Kim, J. H., Sudini, K., Consolini, N., Cormier, S. A., Lomnicki, S., Hasan, F., Pekosz, A. & Biswal, S., Feb 4 2015, In : PloS one. 10, 2, 0116861.

Research output: Contribution to journalArticle

Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype

Singh, A., Wu, H., Zhang, P., Happel, C., Ma, J. & Biswal, S., Aug 2010, In : Molecular cancer therapeutics. 9, 8, p. 2365-2376 12 p.

Research output: Contribution to journalArticle