1993 …2020

Research output per year

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Research Output

Environmental determinants of cardiovascular disease: lessons learned from air pollution

Al-Kindi, S. G., Brook, R. D., Biswal, S. & Rajagopalan, S., Jan 1 2020, (Accepted/In press) In : Nature Reviews Cardiology.

Research output: Contribution to journalReview article

Erratum: Multiple-laboratory comparison of microarray platforms (Nature Methods (2005) vol.2 (345-349))

Irizarry, R. A., Warren, D., Spencer, F., Kim, I. F., Biswal, S., Frank, B. C., Gabrielson, E., Garcia, J. G. N., Geoghegan, J., Germino, G., Griffin, C., Hilmer, S. C., Hoffman, E., Jedlicka, A. E., Kawasaki, E., Martínez-Murillo, F., Morsberger, L., Lee, H., Petersen, D., Quackenbush, J. & 5 others, Scott, A., Wilson, M., Yang, Y., Ye, S. Q. & Yu, W., Jun 2005, In : Nature Methods. 2, 6, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Open Access

Ethanol sensitivity: A central role for CREB transcription regulation in the cerebellum

Acquaah-Mensah, G. K., Misra, V. & Biswal, S., Dec 5 2006, In : BMC genomics. 7, 308.

Research output: Contribution to journalArticle

Ethyl 3′,4′,5′-trimethoxythionocinnamate modulates NF-κB and Nrf2 transcription factors

Kumar, S., Singh, B. K., Prasad, A. K., Parmar, V. S., Biswal, S. & Ghosh, B., Jan 30 2013, In : European Journal of Pharmacology. 700, 1-3, p. 32-41 10 p.

Research output: Contribution to journalArticle

Experimental therapeutics of Nrf2 as a target for prevention of bacterial exacerbations in COPD

Biswal, S., Thimmulappa, R. K. & Harvey, C. J., May 1 2012, In : Proceedings of the American Thoracic Society. 9, 2, p. 47-51 5 p.

Research output: Contribution to journalArticle

Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model

Sussan, T. E., Gajghate, S., Thimmulappa, R. K., Ma, J., Kim, J. H., Sudini, K., Consolini, N., Cormier, S. A., Lomnicki, S., Hasan, F., Pekosz, A. & Biswal, S., Feb 4 2015, In : PloS one. 10, 2, 0116861.

Research output: Contribution to journalArticle

Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype

Singh, A., Wu, H., Zhang, P., Happel, C., Ma, J. & Biswal, S., Aug 2010, In : Molecular cancer therapeutics. 9, 8, p. 2365-2376 12 p.

Research output: Contribution to journalArticle

Field testing of alternative cookstove performance in a rural setting of Western India

Muralidharan, V., Sussan, T. E., Limaye, S., Koehler, K., Williams, DA. L., Rule, A. M., Juvekar, S., Breysse, P. N., Salvi, S. & Biswal, S., Feb 3 2015, In : International journal of environmental research and public health. 12, 2, p. 1773-1787 15 p.

Research output: Contribution to journalArticle

Gain of Nrf2 function in non-small-cell lung cancer cells confers radioresistance

Singh, A., Bodas, M., Wakabayashi, N., Bunz, F. & Biswal, S., Dec 1 2010, In : Antioxidants and Redox Signaling. 13, 11, p. 1627-1637 11 p.

Research output: Contribution to journalArticle

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

Rangasamy, T., Cho, C. Y., Thimmulappa, R. K., Zhen, L., Srisuma, S. S., Kensler, T. W., Yamamoto, M., Petrache, I., Tuder, R. M. & Biswal, S., Nov 1 2004, In : Journal of Clinical Investigation. 114, 9, p. 1248-1259 12 p.

Research output: Contribution to journalArticle

Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice

Papaiahgari, S., Yerrapureddy, A., Reddy, S. R., Reddy, N. M., Dodd-O, J. M., Crow, M. T., Grigoryev, D. N., Barnes, K., Tuder, R. M., Yamamoto, M., Kensler, T. W., Biswal, S., Mitzner, W., Hassoun, P. M. & Reddy, S. P., Dec 15 2007, In : American journal of respiratory and critical care medicine. 176, 12, p. 1222-1235 14 p.

Research output: Contribution to journalArticle

Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection

Reddy, N. M., Kleeberger, S. R., Yamamoto, M., Kensler, T. W., Scollick, C., Biswal, S. & Reddy, S. P., Dec 19 2007, In : Physiological Genomics. 32, 1, p. 74-81 8 p.

Research output: Contribution to journalArticle

Genetic silencing of Nrf2 enhances X-ROS in dysferlin-deficient muscle

Kombairaju, P., Kerr, J. P., Roche, J. A., Pratt, S. J. P., Lovering, R. M., Sussan, T. E., Kim, J. H., Shi, G., Biswal, S. & Ward, C. W., 2014, In : Frontiers in Physiology. 5 FEB, Article 57.

Research output: Contribution to journalArticle

Gestational exposure to sidestream (Secondhand) cigarette smoke promotes transgenerational epigenetic transmission of exacerbated allergic asthma and bronchopulmonary dysplasia

Singh, S. P., Chand, H. S., Langley, R. J., Mishra, N., Barrett, T., Rudolph, K., Tellez, C., Filipczak, P. T., Belinsky, S., Saeed, A. I., Sheybani, A., Exil, V., Agarwal, H., Sidhaye, V. K., Sussan, T., Biswal, S. & Sopori, M., May 15 2017, In : Journal of Immunology. 198, 10, p. 3815-3822 8 p.

Research output: Contribution to journalArticle

Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury

Saleem, S., Zhuang, H., Biswal, S., Christen, Y. & Doré, S., Dec 1 2008, In : Stroke. 39, 12, p. 3389-3396 8 p.

Research output: Contribution to journalArticle

Global expression profiles from C57BL/6J and DBA/2J mouse lungs to determine aging-related genes

Misra, V., Lee, H., Singh, A., Huang, K., Thimmulappa, R. K., Mitzner, W., Biswal, S. & Tankersley, C. G., Nov 14 2007, In : Physiological Genomics. 31, 3, p. 429-440 12 p.

Research output: Contribution to journalArticle

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through chip-seq profiling and network analysis

Malhotra, D., Portales-Casamar, E., Singh, A., Srivastava, S., Arenillas, D., Happel, C., Shyr, C., Wakabayashi, N., Kensler, T. W., Wasserman, W. W. & Biswal, S., May 11 2010, In : Nucleic acids research. 38, 17, p. 5718-5734 17 p., gkq212.

Research output: Contribution to journalArticle

Glutathione oxidation and mitochondrial depolarization as mechanisms of nordihydroguaiaretic acid-induced apoptosis in lipoxygenase-deficient FL5.12 Cells

Biswal, S. S., Datta, K., Shaw, S. D., Feng, X., Robertson, J. D. & Kehrer, J. P., 2000, In : Toxicological Sciences. 53, 1, p. 77-83 7 p.

Research output: Contribution to journalArticle

Open Access

Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2

Singh, A., Rangasamy, T., Thimmulappa, R. K., Lee, H., Osburn, W. O., Brigelius-Flohé, R., Kensler, T. W., Yamamoto, M. & Biswal, S., Dec 1 2006, In : American journal of respiratory cell and molecular biology. 35, 6, p. 639-650 12 p.

Research output: Contribution to journalArticle

Heat-shock protein 70 antisense oligomers enhance proteasome inhibitor-induced apoptosis

Robertson, J. D., Datta, K., Biswal, S. S. & Kehrer, J. P., Dec 1 1999, In : Biochemical Journal. 344, 2, p. 477-485 9 p.

Research output: Contribution to journalArticle

Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: The role of Nrf2-regulated proteasomal activity

Malhotra, D., Thimmulappa, R., Vij, N., Navas-Acien, A., Sussan, T., Merali, S., Zhang, L., Kelsen, S. G., Myers, A., Wise, R., Tuder, R. & Biswal, S., Dec 15 2009, In : American journal of respiratory and critical care medicine. 180, 12, p. 1197-1207 11 p.

Research output: Contribution to journalArticle

Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy

Lounsbury, N., Mateo, G., Jones, B., Papaiahgari, S., Thimmulappa, R. K., Teijaro, C., Gordon, J., Korzekwa, K., Ye, M., Allaway, G., Abou-Gharbia, M., Biswal, S. & Childers, W., Sep 1 2015, In : Bioorganic and Medicinal Chemistry. 23, 17, p. 5352-5359 8 p.

Research output: Contribution to journalArticle

Histone deacetylase 6-mediated selective autophagy regulates copd-associated cilia dysfunction

Lam, H. C., Cloonan, S. M., Bhashyam, A. R., Haspel, J. A., Singh, A., Sathirapongsasuti, J. F., Cervo, M., Yao, H., Chung, A. L., Mizumura, K., An, C. H., Shan, B., Franks, J. M., Haley, K. J., Owen, C. A., Tesfaigzi, Y., Washko, G. R., Quackenbush, J., Silverman, E. K., Rahman, I. & 5 others, Kim, H. P., Mahmood, A., Biswal, S. S., Ryter, S. W. & Choi, A. M. K., Dec 2 2013, In : Journal of Clinical Investigation. 123, 12, p. 5212-5230 19 p.

Research output: Contribution to journalArticle

Identification of genes promoting angiogenesis in mouse lung by transcriptional profiling

Srisuma, S., Biswal, S. S., Mitzner, W. A., Gallagher, S. J., Mai, K. H. & Wagner, E. M., Aug 1 2003, In : American journal of respiratory cell and molecular biology. 29, 2, p. 172-179 8 p.

Research output: Contribution to journalArticle

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray

Thimmulappa, R. K., Mai, K. H., Srisuma, S., Kensler, T. W., Yamamoto, M. & Biswal, S., Sep 15 2002, In : Cancer Research. 62, 18, p. 5196-5203 8 p.

Research output: Contribution to journalArticle

Identification of transcriptional targets of HOXA5

Chen, H., Rubin, E., Zhang, H., Chung, S., Jie, C. C., Garrett, E., Biswal, S. & Sukumar, S., May 13 2005, In : Journal of Biological Chemistry. 280, 19, p. 19373-19380 8 p.

Research output: Contribution to journalArticle

Immune modulation by chronic exposure to waterpipe smoke and immediate-early gene regulation in murine lungs

Reyes-Caballero, H., Park, B., Loube, J., Sanchez, I., Vinayachandran, V., Choi, Y., Woo, J., Edwards, J., Brinkman, M. C., Sussan, T. E., Mitzner, W. & Biswal, S., Jan 1 2019, (Accepted/In press) In : Tobacco control.

Research output: Contribution to journalArticle

Impaired calcium signaling in muscle fibers from intercostal and foot skeletal muscle in a cigarette smoke-induced mouse model of COPD

Robison, P., Sussan, T. E., Chen, H., Biswal, S., Schneider, M. F. & Hernández-Ochoa, E. O., 2017, (Accepted/In press) In : Muscle and Nerve.

Research output: Contribution to journalArticle

Impaired lung homeostasis in neonatal mice exposed to cigarette smoke

McGrath-Morrow, S., Rangasamy, T., Cho, C., Sussan, T., Neptune, E., Wise, R., Tuder, R. M. & Biswal, S., Apr 1 2008, In : American journal of respiratory cell and molecular biology. 38, 4, p. 393-400 8 p.

Research output: Contribution to journalArticle

Individual and joint effects of early-life ambient PM2.5 exposure and maternal prepregnancy obesity on childhood overweight or obesity

Mao, G., Nachman, R. M., Sun, Q., Zhang, X., Koehler, K., Chen, Z., Hong, X., Wang, G., Caruso, D., Zong, G., Pearson, C., Ji, H., Biswal, S., Zuckerman, B., Wills-Karp, M. & Wang, X., Jun 2017, In : Environmental health perspectives. 125, 6, 067005.

Research output: Contribution to journalArticle

Indoor particulate matter < 2.5 μm in mean aerodynamic diameter and carbon monoxide levels during the burning of mosquito coils and their association with respiratory health

Salvi, D., Limaye, S., Muralidharan, V., Londhe, J., Madas, S., Juvekar, S., Biswal, S. & Salvi, S., Feb 2016, In : CHEST. 149, 2, p. 459-466 8 p.

Research output: Contribution to journalArticle

Inhibition of cell proliferation and AP-1 activity by acrolein in human A549 lung adenocarcinoma cells due to thiol imbalance and covalent modifications

Biswal, S., Acquaah-Mensah, G., Datta, K., Wu, X. & Kehrer, J. P., Mar 4 2002, In : Chemical research in toxicology. 15, 2, p. 180-186 7 p.

Research output: Contribution to journalArticle

Inhibition of peroxisome-proliferator-activated receptor (PPAR)α by MK886

Kehrer, J. P., Biswal, S. S., La, E., Thuillier, P., Datta, K., Fischer, S. M. & Vanden Heuvel, J. P., Jun 15 2001, In : Biochemical Journal. 356, 3, p. 899-906 8 p.

Research output: Contribution to journalArticle

Intrauterine inflammation and maternal exposure to ambient pm2.5 during preconception and specific periods of pregnancy: The boston birth cohort

Nachman, R. M., Mao, G., Zhang, X., Hong, X., Chen, Z., Soria, C. S., He, H., Wang, G., Caruso, D., Pearson, C., Biswal, S., Zuckerman, B., Wills-Karp, M. & Wang, X., Oct 1 2016, In : Environmental Health Perspectives. 124, 10, p. 1608-1615 8 p.

Research output: Contribution to journalArticle

Knockout of the transcription factor Nrf2: Effects on testosterone production by aging mouse Leydig cells

Chen, H., Jin, S., Guo, J., Kombairaju, P., Biswal, S. & Zirkin, B. R., Jul 5 2015, In : Molecular and Cellular Endocrinology. 409, p. 113-120 8 p.

Research output: Contribution to journalArticle

Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: A randomized, double-blind, placebo controlled trial

Wise, R. A., Holbrook, J. T., Criner, G., Sethi, S., Rayapudi, S., Sudini, K. R., Sugar, E. A., Burke, A., Thimmulappa, R., Singh, A., Talalay, P., Fahey, J. W., Berenson, C. S., Jacobs, M. R., Biswal, S., Leatherman, G., Daniel, M., Thurman, A., Marchetti, N., Kim, V. & 25 others, Shenoy, K., Smith, H., Rosario, M., Bolla, S., Mandapati, C., Eberhardt, E., Kruzel, R., Kumar, S., Noel, S., Beselman, A., Amend-Libercci, D., Ewing, C., Hart, A., Lears, A., Nowakowski, D., Prusakowski, N., Shade, D., Yasin, R., Brown, E., Wang, L., O'Connor, G., Strange, C., Wendt, C., Punturieri, A. & Viviano, L. W., Nov 2016, In : PloS one. 11, 11, e0163716.

Research output: Contribution to journalArticle

Linoleic acid metabolite drives severe asthma by causing airway epithelial injury

Mabalirajan, U., Rehman, R., Ahmad, T., Kumar, S., Singh, S., Leishangthem, G. D., Aich, J., Kumar, M., Khanna, K., Singh, V. P., Dinda, A. K., Biswal, S., Agrawal, A. & Ghosh, B., 2013, In : Scientific reports. 3, 1349.

Research output: Contribution to journalArticle

Long term environmental tobacco smoke activates nuclear transcription factor-kappa B, activator protein-1, and stress responsive kinases in mouse brain

Manna, S. K., Rangasamy, T., Wise, K., Sarkar, S., Shishodia, S., Biswal, S. & Ramesh, G. T., May 28 2006, In : Biochemical Pharmacology. 71, 11, p. 1602-1609 8 p.

Research output: Contribution to journalArticle

Loss of kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth

Zhang, P., Singh, A., Yegnasubramanian, S., Esopi, D., Kombairaju, P., Bodas, M., Wu, H., Bova, S. G. & Biswal, S., Feb 2010, In : Molecular cancer therapeutics. 9, 2, p. 336-346 11 p.

Research output: Contribution to journalArticle

Marburgvirus Hijacks Nrf2-Dependent Pathway by Targeting Nrf2-Negative Regulator Keap1

Page, A., Volchkova, V. A., Reid, S. P., Mateo, M., Bagnaud-Baule, A., Nemirov, K., Shurtleff, A. C., Lawrence, P., Reynard, O., Ottmann, M., Lotteau, V., Biswal, S. S., Thimmulappa, R. K., Bavari, S. & Volchkov, V. E., Mar 27 2014, In : Cell Reports. 6, 6, p. 1026-1036 11 p.

Research output: Contribution to journalArticle

Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis

Bhalla, K., Hwang, B. J., Dewi, R. E., Twaddel, W., Goloubeva, O. G., Wong, K. K., Saxena, N. K., Biswal, S. & Girnun, G. D., Apr 2012, In : Cancer Prevention Research. 5, 4, p. 544-552 9 p.

Research output: Contribution to journalArticle

Modulation of benzo[a]pyrene-induced p53 DNA activity by acrolein

Biswal, S., Maxwell, T., Rangasamy, T. & Kehrer, J. P., Aug 1 2003, In : Carcinogenesis. 24, 8, p. 1401-1406 6 p.

Research output: Contribution to journalArticle

Multiple-laboratory comparison of microarray platforms

Irizarry, R. A., Warren, D., Spencer, F., Kim, I. F., Biswal, S., Frank, B. C., Gabrielson, E., Garcia, J. G. N., Geoghegan, J., Germino, G., Griffin, C., Hilmer, S. C., Hoffman, E., Jedlicka, A. E., Kawasaki, E., Martínez-Murillo, F., Morsberger, L., Lee, H., Petersen, D., Quackenbush, J. & 5 others, Scott, A., Wilson, M., Yang, Y., Ye, S. Q. & Yu, W., May 1 2005, In : Nature Methods. 2, 5, p. 345-349 5 p.

Research output: Contribution to journalArticle

NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice

Kong, X., Thimmulappa, R., Kombairaju, P. & Biswal, S., Jul 1 2010, In : Journal of Immunology. 185, 1, p. 569-577 9 p.

Research output: Contribution to journalArticle