Shridhar Bhat

Research Associate

1992 …2018
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Fingerprint Dive into the research topics where Shridhar Bhat is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Aminopeptidases Medicine & Life Sciences
Methionine Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Biological Products Medicine & Life Sciences
Mycobacterium tuberculosis Medicine & Life Sciences
Itraconazole Medicine & Life Sciences
Tacrolimus Binding Proteins Medicine & Life Sciences
Endothelial cells Chemical Compounds

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Research Output 1992 2018

Hydrazide Mimics for Protein Lysine Acylation to Assess Nucleosome Dynamics and Deubiquitinase Action

Bhat, S., Hwang, Y. S., Gibson, M. D., Morgan, M., Taverna, S. D., Zhao, Y., Wolberger, C., Poirier, M. G. & Cole, P. A., Aug 1 2018, In : Journal of the American Chemical Society. 140, 30, p. 9478-9485 8 p.

Research output: Contribution to journalArticle

Acylation
Nucleosomes
Lysine
Proteins
Histones

Rapamycin-inspired macrocycles with new target specificity

Guo, Z., Hong, S. Y., Wang, J., Rehan, S., Liu, W., Peng, H., Das, M., Li, W., Bhat, S., Peiffer, B., Ullman, B. R., Tse, C. M., Tarmakova, Z., Schiene-Fischer, C., Fischer, G., Coe, I., Paavilainen, V. O., Sun, Z. L. & Liu, J., Jan 1 2018, (Accepted/In press) In : Nature Chemistry.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Sirolimus
Calcineurin
Proteins
Equilibrative Nucleoside Transporter 1

Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP)

Bauer, L., Ferla, S., Head, S. A., Bhat, S., Pasunooti, K. K., Shi, W. Q., Albulescu, L., Liu, J., Brancale, A., van Kuppeveld, F. J. M. & Strating, J. R. P. M., Aug 1 2018, In : Antiviral Research. 156, p. 55-63 9 p.

Research output: Contribution to journalArticle

Picornaviridae
Itraconazole
Structure-Activity Relationship
Antiviral Agents
Cardiovirus

Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1

Zhang, P., Yang, X., Zhang, F., Gabelli, S. B., Wang, R., Zhang, Y., Bhat, S., Chen, X., Furlani, M., Amzel, M. L., Liu, J. & Ma, D., May 1 2013, In : Bioorganic and Medicinal Chemistry. 21, 9, p. 2600-2617 18 p.

Research output: Contribution to journalArticle

Aminopeptidases
Methionine
Structure-Activity Relationship
Mammals
Pharmaceutical Chemistry

Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells

Zhang, F., Bhat, S., Gabelli, S. B., Chen, X., Miller, M. S., Nacev, B. A., Cheng, Y. L., Meyers, D. J., Tenney, K., Shim, J. S., Crews, P., Amzel, M. L., Ma, D. & Liu, J., May 23 2013, In : Journal of Medicinal Chemistry. 56, 10, p. 3996-4016 21 p.

Research output: Contribution to journalArticle

Aminopeptidases
Methionine
Quinazolines
Mammals
Metals