Shiwen Peng

Research Associate

19962018
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1996 2018

Filter
Article
2018

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer

Anchoori, R., Jiang, R., Peng, S., Soong, R. S., Algethami, A., Rudek-Renaut, M., Anders, N., Hung, C-F., Chen, X., Lu, X., Kayode, O., Dyba, M., Walters, K. J. & Roden, R. S., Sep 30 2018, In : ACS Omega. 3, 9, p. 11917-11929 13 p.

Research output: Contribution to journalArticle

Proteins
Cells
Tumors
Bearings (structural)
Firefly Luciferases

Epithelial boost enhances antigen expression by vaccinia virus for the generation of potent CD8+ T cell-mediated antitumor immunity following DNA priming vaccination

Qiu, J., Peng, S., Ma, Y., Yang, A., Farmer, E., Cheng, M. A., Roden, R. S., Wu, T. C., Chang, Y. N. & Hung, C-F., Dec 1 2018, In : Virology. 525, p. 205-215 11 p.

Research output: Contribution to journalArticle

DNA Vaccines
Vaccinia virus
Cellular Immunity
Immunization
Vaccination

Integration of oncogenes via sleeping beauty as a mouse model of HPV16þ oral tumors and immunologic control

Lin, Y. H., Yang, M. C., Tseng, S. H., Jiang, R., Yang, A., Farmer, E., Peng, S., Henkle, T., Chang, Y. N., Hung, C-F. & Wu, T. C., Mar 1 2018, In : Cancer immunology research. 6, 3, p. 305-319 15 p.

Research output: Contribution to journalArticle

Beauty
Human papillomavirus 16
Oncogenes
Neoplasms
Luciferases

Intramuscular vaccination targeting mucosal tumor draining lymph node enhances integrins-mediated CD8+ T cell infiltration to control mucosal tumor growth

Qiu, J., Peng, S., Yang, A., Ma, Y., Han, L., Cheng, M. A., Farmer, E., Hung, C-F. & Wu, T. C., May 23 2018, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

Integrins
Vaccination
Lymph Nodes
T-Lymphocytes
Growth

Programmed self-assembly of peptide–major histocompatibility complex for antigen-specific immune modulation

Mao, C. P., Peng, S., Yang, A., He, L., Tsai, Y. C., Hung, C-F. & Wu, T. C., Apr 24 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 17, p. E4032-E4040

Research output: Contribution to journalArticle

Histocompatibility Antigens
Major Histocompatibility Complex
T-Lymphocytes
Technology
Annexin A5

Prophylactic immunization with human papillomavirus vaccines induces oral immunity in mice

Ahn, J., Peng, S., Hung, C-F., Roden, R. S. & Best, S. R., Jan 1 2018, In : Laryngoscope. 128, 1, p. E16-E20

Research output: Contribution to journalArticle

Papillomavirus Vaccines
Immunity
Immunization
Luciferases
Papillomavirus Infections
2017

Characterization of HPV18 E6-specific T cell responses and establishment of HPV18 E6-expressing tumor model

Ma, Y., Yang, A., Peng, S., Qiu, J., Farmer, E., Hung, C-F. & Wu, T. C., Jul 5 2017, In : Vaccine. 35, 31, p. 3850-3858 9 p.

Research output: Contribution to journalArticle

T-lymphocytes
epitopes
T-Lymphocytes
Epitopes
DNA Vaccines

Coinjection of IL2 DNA enhances E7-specific antitumor immunity elicited by intravaginal therapeutic HPV DNA vaccination with electroporation

Sun, Y., Peng, S., Yang, A., Farmer, E., Wu, T. C. & Hung, C-F., Jul 1 2017, In : Gene Therapy. 24, 7, p. 408-415 8 p.

Research output: Contribution to journalArticle

Electroporation
Interleukin-2
Immunity
Vaccination
Papillomavirus Vaccines

Enhancing antitumor immunogenicity of HPV16-E7 DNA vaccine by fusing DNA encoding E7-antigenic peptide to DNA encoding capsid protein L1 of Bovine papillomavirus

Yang, A., Peng, S., Farmer, E., Zeng, Q., Cheng, M. A., Pang, X., Wu, T. C. & Hung, C-F., Aug 23 2017, In : Cell and Bioscience. 7, 1, 46.

Research output: Contribution to journalArticle

DNA Vaccines
T-cells
Capsid Proteins
T-Lymphocytes
Fusion reactions

Immunologic responses to a novel DNA vaccine targeting human papillomavirus-11 E6E7

Ahn, J., Peng, S., Hung, C-F., Roden, R. S., Wu, T. C. & Best, S. R., 2017, (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Human papillomavirus 11
DNA Vaccines
Calreticulin
Vaccines
T-Lymphocytes

Spontaneous and vaccine-induced clearance of Mus musculus papillomavirus 1 infection

Jiang, R. T., Wang, J. W., Peng, S., Huang, T. C., Wang, C., Cannella, F., Chang, Y. N., Viscidi, R. P., Best, S. R., Hung, C-F. & Roden, R. S., Aug 1 2017, In : Journal of Virology. 91, 15, e00699-17.

Research output: Contribution to journalArticle

Papillomavirus Infections
Papillomaviridae
Mus musculus
papilloma
Papilloma
2016

Identification of the murine H-2Db and human HLA-A*0201 MHC class I-restricted HPV6 E7-specific cytotoxic T lymphocyte epitopes

Peng, S., Mattox, A., Best, S. R., Barbu, A. M., Burns, J. A., Akpeng, B., Jeang, J., Yang, B., Ishida, E., Hung, C-F., Wu, T. C. & Pai, S. I., Mar 1 2016, In : Cancer Immunology Immunotherapy. 65, 3, p. 261-271 11 p.

Research output: Contribution to journalArticle

T-Lymphocyte Epitopes
Cytotoxic T-Lymphocytes
Human papillomavirus 11
T-Lymphocytes
Calreticulin

Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell-Mediated Tumor Control in the Genital Tract

Sun, Y. Y., Peng, S., Han, L., Qiu, J., Song, L., Tsai, Y., Yang, B., Roden, R. S., Trimble, C. L., Hung, C-F. & Wu, T. C., Feb 1 2016, In : Clinical Cancer Research. 22, 3, p. 657-669 13 p.

Research output: Contribution to journalArticle

Papillomavirus Vaccines
Vaccinia
DNA Vaccines
Vaccination
T-Lymphocytes

Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease

Peng, S., Qiu, J., Yang, A., Yang, B., Jeang, J., Wang, J. W., Chang, Y. N., Brayton, C., Roden, R. S., Hung, C-F. & Wu, T. C., Feb 25 2016, In : Cell and Bioscience. 6, 1, 16.

Research output: Contribution to journalArticle

DNA Vaccines
Papillomavirus Vaccines
Immunity
Vaccination
T-cells
2015
Calreticulin
Capsid Proteins
Therapeutic Uses
DNA Vaccines
T-cells
Proteasome Inhibitors
Histone Deacetylase Inhibitors
T-cells
Uterine Cervical Neoplasms
Tumors

Immunologic Control of Mus musculus Papillomavirus Type 1

Wang, J. W., Jiang, R., Peng, S., Chang, Y. N., Hung, C-F. & Roden, R. S., 2015, In : PLoS Pathogens. 11, 10, e1005243.

Research output: Contribution to journalArticle

T-Lymphocytes
Papilloma
Inbred C57BL Mouse
Antibodies
Capsid

Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T-cell immune responses and antitumor effects against cervicovaginal tumors

Sun, Y., Peng, S., Qiu, J., Miao, J., Yang, B., Jeang, J., Hung, C-F. & Wu, T. C., Jul 3 2015, In : Gene Therapy. 22, 7, p. 528-535 8 p.

Research output: Contribution to journalArticle

Electroporation
Calreticulin
Vaccination
T-Lymphocytes
DNA Vaccines

Local administration of granulocyte macrophage colony-stimulating factor induces local accumulation of dendritic cells and antigen-specific CD8+ T cells and enhances dendritic cell cross-presentation

Lee, S. J., Song, L., Yang, M. C., Mao, C. P., Yang, B., Yang, A., Jeang, J., Peng, S., Wu, T. C. & Hung, C-F., Mar 24 2015, In : Vaccine. 33, 13, p. 1549-1555 7 p.

Research output: Contribution to journalArticle

Cross-Priming
CD8 Antigens
granulocyte-macrophage colony-stimulating factor
dendritic cells
Granulocyte-Macrophage Colony-Stimulating Factor

Production of furin-cleaved Papillomavirus pseudovirions and their use for in vitro neutralization assays of L1-or L2-specific antibodies

Wang, J. W., Kwak, K., Peng, S., Kemp, T., Pinto, L. & Roden, R. S., 2015, In : Current Protocols in Microbiology. 2015, p. 14B.5.1-14B.5.26

Research output: Contribution to journalArticle

Furin
Neutralizing Antibodies
Papillomaviridae
Virion
Antibodies

Sequential cisplatin therapy and vaccination with HPV16 E6E7L2 fusion protein in saponin adjuvant GPI-0100 for the treatment of a model HPV16+ cancer

Peng, S., Wang, J. W., Karanam, B., Wang, C., Huh, W. K., Alvarez, R. D., Pai, S. I., Hung, C-F., Wu, T. C. & Roden, R. S., Jan 5 2015, In : PLoS One. 10, 1, e116389.

Research output: Contribution to journalArticle

cisplatin
Saponins
saponins
Cisplatin
adjuvants
2014

Control of HPV-associated tumors by innovative therapeutic HPV DNA vaccine in the absence of CD4+ T cells

Peng, S., Song, L., Knoff, J., Wang, J. W., Chang, Y. N., Hannaman, D., Wu, T. C., Alvarez, R. D., Roden, R. S. & Hung, C-F., Mar 4 2014, In : Cell and Bioscience. 4, 1, 11.

Research output: Contribution to journalArticle

Papillomavirus Vaccines
DNA Vaccines
T-cells
Tumors
T-Lymphocytes

Corrigendum to "vaccination with hpv16 l2e6e7 fusion protein in gpi-0100 adjuvant elicits protective humoral and cell-mediated immunity" [vaccine 27 (2009) 1040-1049]

Karanam, B., Gambhira, R., Peng, S., Jagu, S., Kim, D. J., Ketner, G. W., Stern, P. L., Adams, R. J. & Roden, R. S., Jan 3 2014, In : Vaccine. 32, 2, p. 309 1 p.

Research output: Contribution to journalArticle

Cellular Immunity
cell-mediated immunity
adjuvants
Vaccination
Vaccines

Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors

Wu, C. Y., Yang, L. H., Yang, H. Y., Knoff, J., Peng, S., Lin, Y. H., Wang, C., Alvarez, R. D., Pai, S. I., Roden, R. S., Hung, C-F. & Wu, T. C., 2014, In : Clinical Cancer Research. 20, 3, p. 644-657 14 p.

Research output: Contribution to journalArticle

Immunosuppressive Agents
Stromal Cells
Radiotherapy
Myeloid Cells
Neoplasms

Mhc-ig induces memory t cell formation in vivo and inhibits tumour growth

Schütz, C., Zoso, A., Peng, S., Bennett, J. D., Schneck, J. P. & Oelke, M., Jan 1 2014, In : Immunity Inflammation and Disease. 2, 3

Research output: Contribution to journalArticle

Open Access
T-Lymphocytes
Growth
Neoplasms
Antigens
Active Immunotherapy

Preparation and properties of a papillomavirus infectious intermediate and its utility for neutralization studies

Wang, J. W., Jagu, S., Kwak, K., Wang, C., Peng, S., Kirnbauer, R. & Roden, R. S., Jan 20 2014, In : Virology. 449, p. 304-316 13 p.

Research output: Contribution to journalArticle

Furin
Neutralizing Antibodies
Virion
Amyloid Precursor Protein Secretases
Antibodies
2013

A bis-Benzylidine Piperidone Targeting Proteasome Ubiquitin Receptor RPN13/ADRM1 as a Therapy for Cancer

Anchoori, R., Karanam, B., Peng, S., Wang, J., Jiang, R., Tanno, T., Orlowski, R., Matsui, W., Zhao, M., Rudek-Renaut, M., Hung, C-F., Chen, X., Walters, K. & Roden, R. S., Dec 9 2013, In : Cancer Cell. 24, 6, p. 791-805 15 p.

Research output: Contribution to journalArticle

Piperidones
Proteasome Endopeptidase Complex
Ubiquitin
Multiple Myeloma
Neoplasms

Evidence for a role of the PD-1: PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma

Lyford-Pike, S., Peng, S., Young, G. D., Taube, J. M., Westra, W. H., Akpeng, B., Bruno, T. C., Richmon, J. D., Wang, H., Bishop, J. A., Chen, L., Drake, C. G., Topalian, S., Pardoll, A. M. & Pai, S. I., Mar 15 2013, In : Cancer Research. 73, 6, p. 1733-1741 9 p.

Research output: Contribution to journalArticle

Neoplasms
Lymphocytes
Tumor-Infiltrating Lymphocytes
Palatine Tonsil
Virus Diseases

Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine

Peng, S., Lyford-Pike, S., Akpeng, B., Wu, A., Hung, C-F., Hannaman, D., Saunders, J. R., Wu, T. C. & Pai, S. I., Jan 2013, In : Cancer Immunology Immunotherapy. 62, 1, p. 171-182 12 p.

Research output: Contribution to journalArticle

Papillomavirus Vaccines
Therapeutic Uses
Cyclophosphamide
T-Lymphocytes
Vaccines
2012

Development of a DNA vaccine targeting Merkel cell polyomavirus

Zeng, Q., Gomez, B. P., Viscidi, R. P., Peng, S., He, L., Ma, B., Wu, T. C. & Hung, C-F., Feb 8 2012, In : Vaccine. 30, 7, p. 1322-1329 8 p.

Research output: Contribution to journalArticle

Merkel cell polyomavirus
Polyomavirus
DNA Vaccines
Viral Tumor Antigens
recombinant vaccines
Merkel cell polyomavirus
CD8 Antigens
Merkel Cell Carcinoma
Polyomavirus Transforming Antigens
T-cells
2011

Control of cervicovaginal HPV-16 E7-expressing tumors by the combination of therapeutic HPV vaccination and vascular disrupting agents

Zeng, Q., Peng, S., Monie, A., Yang, M., Pang, X., Hung, C-F. & Wu, T. C., Jul 1 2011, In : Human Gene Therapy. 22, 7, p. 809-819 11 p.

Research output: Contribution to journalArticle

Human papillomavirus 16
Acetic Acid
Blood Vessels
Vaccination
Neoplasms
CD8 Antigens
DNA Vaccines
T-cells
Ovalbumin
Immunity

Innovative DNA vaccine for human papillomavirus (HPV)-associated head and neck cancer

Wu, A., Zeng, Q., Kang, T. H., Peng, S., Roosinovich, E., Pai, S. I. & Hung, C-F., Mar 2011, In : Gene Therapy. 18, 3, p. 304-312 9 p.

Research output: Contribution to journalArticle

DNA Vaccines
Head and Neck Neoplasms
Epitopes
T-Lymphocytes
DNA

In vivo microRNA-155 expression influences antigen-specific T cell-mediated immune responses generated by DNA vaccination

Mao, C. P., He, L., Tsai, Y. C., Peng, S., Kang, T. H., Pang, X., Monie, A., Hung, C-F. & Wu, T. C., Jan 18 2011, In : Cell and Bioscience. 1, 1, 3.

Research output: Contribution to journalArticle

T-cells
MicroRNAs
Vaccination
Dendritic Cells
T-Lymphocytes

Stressing the ubiquitin-proteasome system without 20s proteolytic inhibition Selectively Kills cervical cancer cells

Anchoori, R., Khan, S. R., Sueblinvong, T., Felthauser, A., Iizuka, Y., Gavioli, R., Destro, F., Vogel, R. I., Peng, S., Roden, R. S. & Bazzaro, M., 2011, In : PLoS One. 6, 8, e23888.

Research output: Contribution to journalArticle

uterine cervical neoplasms
proteasome endopeptidase complex
Proteasome Endopeptidase Complex
ubiquitin
Ubiquitin
Papillomavirus Vaccines
DNA Vaccines
Therapeutic Uses
Acetic Acid
Blood Vessels
2010

Characterization of human papillomavirus type 11-specific immune responses in a preclinical model

Peng, S., Best, S. R., Hung, C-F., Loyo, M., Lyford-Pike, S., Flint, P. W., Tunkel, D. E., Saunders, J. R., Wu, T. C. & Pai, S. I., Mar 2010, In : Laryngoscope. 120, 3, p. 504-510 7 p.

Research output: Contribution to journalArticle

Human papillomavirus 11
DNA Vaccines
Vaccines
T-Lymphocytes
Peptides

Differential expression of epidermal growth factor receptor in juvenile and adult-onset recurrent respiratory papillomatosis

Lyford-Pike, S., Westra, W. H., Loyo, M., Peng, S., Hung, C-F., Wu, A. A., Flint, P. W., Tunkel, D. E., Saunders, J. R. & Pai, S. I., Nov 2010, In : Histopathology. 57, 5, p. 768-770 3 p.

Research output: Contribution to journalArticle

Neoplastic Cell Transformation
Respiratory Mucosa
Papillomavirus Infections
Preschool Children
Epidermal Growth Factor Receptor

Efficient delivery of DNA vaccines using human papillomavirus pseudovirions

Peng, S., Monie, A., Kang, T. H., Hung, C-F., Roden, R. S. & Wu, T. C., Dec 2010, In : Gene Therapy. 17, 12, p. 1453-1464 12 p.

Research output: Contribution to journalArticle

DNA Vaccines
Ovalbumin
Vaccination
Dendritic Cells
Bone Marrow

Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3

Trimble, C. L., Peng, S., Thoburn, C., Kos, F. & Wu, T. C., May 2010, In : Cancer Immunology Immunotherapy. 59, 5, p. 799-803 5 p.

Research output: Contribution to journalArticle

Conization
Antigens
Cervical Intraepithelial Neoplasia
Time and Motion Studies
Papillomavirus Infections

Papillomavirus infection requires γ secretase

Karanam, B., Peng, S., Li, T., Buck, C., Day, P. M. & Roden, R. S., Oct 2010, In : Journal of Virology. 84, 20, p. 10661-10670 10 p.

Research output: Contribution to journalArticle

Amyloid Precursor Protein Secretases
Papillomavirus Infections
Papillomaviridae
Human papillomavirus 16
infection
2009

Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery

Best, S. R., Peng, S., Juang, C. M., Hung, C-F., Hannaman, D., Saunders, J. R., Wu, T. C. & Pai, S. I., Sep 4 2009, In : Vaccine. 27, 40, p. 5450-5459 10 p.

Research output: Contribution to journalArticle

Papillomavirus Vaccines
DNA Vaccines
Electroporation
electroporation
Intramuscular Injections
Papillomavirus Vaccines
DNA Vaccines
Cervical Intraepithelial Neoplasia
Vaccination
Safety

Combination of proteasome and HDAC inhibitors for uterine cervical cancer treatment

Lin, Z., Bazzaro, M., Wang, M. C., Chan, K. C., Peng, S. & Roden, R. S., Jan 15 2009, In : Clinical Cancer Research. 15, 2, p. 570-577 8 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Proteasome Endopeptidase Complex
Uterine Cervical Neoplasms
trichostatin A
Oncogene Proteins

Vaccination with HPV16 L2E6E7 fusion protein in GPI-0100 adjuvant elicits protective humoral and cell-mediated immunity

Karanam, B., Gambhira, R., Peng, S., Jagu, S., Kim, D. J., Ketner, G. W., Stern, P. L., Adams, R. J. & Roden, R. S., Feb 11 2009, In : Vaccine. 27, 7, p. 1040-1049 10 p.

Research output: Contribution to journalArticle

Human papillomavirus 16
Papillomaviridae
Cellular Immunity
cell-mediated immunity
adjuvants
2008

Cluster intradermal DNA vaccination rapidly induces E7-specific CD8+ T-cell immune responses leading to therapeutic antitumor effects

Peng, S., Trimble, C. L., Alvarez, R. D., Huh, W. K., Lin, Z., Monie, A., Hung, C-F. & Wu, T. C., 2008, In : Gene Therapy. 15, 16, p. 1156-1166 11 p.

Research output: Contribution to journalArticle

Therapeutic Uses
Calreticulin
Vaccination
T-Lymphocytes
DNA

RNA interference-mediated in vivo silencing of Fas ligand as a strategy for the enhancement of DNA vaccine potency

Huang, B., Mao, C. P., Peng, S., Hung, C-F. & Wu, T. C., Aug 1 2008, In : Human Gene Therapy. 19, 8, p. 763-773 11 p.

Research output: Contribution to journalArticle

Vaccine Potency
DNA Vaccines
Fas Ligand Protein
RNA Interference
Luciferases
2007

Ectopic expression of vascular cell adhesion molecule-1 as a new mechanism for tumor immune evasion

Lin, K. Y., Lu, D., Hung, C-F., Peng, S., Huang, L., Jie, C., Murillo, F., Rowley, J., Tsai, Y. C., He, L., Kim, D. J., Jaffee, E., Pardoll, A. M. & Wu, T. C., Feb 15 2007, In : Cancer Research. 67, 4, p. 1832-1841 10 p.

Research output: Contribution to journalArticle

Tumor Escape
Vascular Cell Adhesion Molecule-1
Renal Cell Carcinoma
Neoplasms
Integrins

Enhancing dendritic cell vaccine potency by combining a BAK/BAX siRNA-mediated antiapoptotic strategy to prolong dendritic cell life with an intracellular strategy to target antigen to lysosomal compartments

Kang, T. H., Lee, J. H., Noh, K. H., Han, H. D., Shin, B. C., Choi, E. Y., Peng, S., Hung, C-F., Wu, T. C. & Kim, T. W., Apr 15 2007, In : International Journal of Cancer. 120, 8, p. 1696-1703 8 p.

Research output: Contribution to journalArticle

Vaccine Potency
Dendritic Cells
Small Interfering RNA
Antigens
Lysosome-Associated Membrane Glycoproteins