Shichun Lun

Research Associate

20032019
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Mycobacterium tuberculosis Medicine & Life Sciences
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Mycolic Acids Medicine & Life Sciences
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Research Output 2003 2019

Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II

Zhang, W., Lun, S., Liu, L. L., Xiao, S., Duan, G., Gunosewoyo, H., Yang, F., Tang, J., Bishai, W. R. & Yu, L. F., Apr 11 2019, In : Journal of medicinal chemistry. 62, 7, p. 3575-3589 15 p.

Research output: Contribution to journalArticle

Polyketide Synthases
Mycobacterium tuberculosis
Multidrug-Resistant Tuberculosis
Isoniazid
Structure-Activity Relationship

Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis

Zhang, W., Lun, S., Wang, S. H., Jiang, X. W., Yang, F., Tang, J., Manson, A. L., Earl, A. M., Gunosewoyo, H., Bishai, W. R. & Yu, L. F., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 791-803 13 p.

Research output: Contribution to journalArticle

Mycolic Acids
Antitubercular Agents
Polyketide Synthases
Mycobacterium tuberculosis
Benzofurans

Targeting Mycolic Acid Transport by Indole-2-carboxamides for the Treatment of Mycobacterium abscessus Infections

Kozikowski, A. P., Onajole, O. K., Stec, J., Dupont, C., Viljoen, A., Richard, M., Chaira, T., Lun, S., Bishai, W. R., Raj, V. S., Ordway, D. & Kremer, L., Jul 13 2017, In : Journal of Medicinal Chemistry. 60, 13, p. 5876-5888 13 p.

Research output: Contribution to journalArticle

Mycolic Acids
Mycobacterium Infections
Cystic Fibrosis
Cord Factors
Mycobacterium

Indole-2-carboxamide-based MmpL3 Inhibitors Show Exceptional Antitubercular Activity in an Animal Model of Tuberculosis Infection

Stec, J., Onajole, O. K., Lun, S., Guo, H., Merenbloom, B., Vistoli, G., Bishai, W. R. & Kozikowski, A. P., Jul 14 2016, In : Journal of Medicinal Chemistry. 59, 13, p. 6232-6247 16 p.

Research output: Contribution to journalArticle

Tuberculosis
Animal Models
Rifampin
Infection
Aerosols

Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis

Maiga, M., Ahidjo, B. A., Maiga, M. C., Cheung, L., Pelly, S., Lun, S., Bougoudogo, F. & Bishai, W. R., Aug 1 2015, In : EBioMedicine. 2, 8, p. 868-873 6 p.

Research output: Contribution to journalArticle

Tuberculosis
Mycobacterium tuberculosis
Janus Kinases
Therapeutics
Mycobacterium Infections