Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Neoplasms Medicine & Life Sciences
Histones Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Lysine Medicine & Life Sciences
Pyridines Medicine & Life Sciences
Mutation Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1997 2015

Histone-Lysine N-Methyltransferase
Epigenomics
Neoplasms
Enhancer of Zeste Homolog 2 Protein
Pharmaceutical Preparations

Recent progress in the discovery of epigenetic inhibitors for the treatment of cancer

Verma, S. K. 2015 In : Methods in Molecular Biology. 1238, p. 677-688 12 p.

Research output: Research - peer-reviewArticle

Epigenomics
Neoplasms
histone methyltransferase
Antineoplastic Agents
Enzymes

A687V EZH2 is a driver of histone H3 Lysine 27 (H3K27) hypertrimethylation

Ott, H. M., Graves, A. P., Pappalardi, M. B., Huddleston, M., Halsey, W. S., Hughes, A. M., Groy, A., Dul, E., Jiang, Y., Bai, Y., Annan, R., Verma, S. K., Knight, S. D., Kruger, R. G., Dhanak, D., Schwartz, B., Tummino, P. J., Creasy, C. L. & McCabe, M. T. Dec 1 2014 In : Molecular Cancer Therapeutics. 13, 12, p. 3062-3073 12 p.

Research output: Research - peer-reviewArticle

Histones
Lysine
Mutation
Cell Line
Catalytic Domain

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

MacK, S. C. , Witt, H. , Piro, R. M. , Gu, L. , Zuyderduyn, S. , Stütz, A. M. , Wang, X. , Gallo, M. , Garzia, L. , Zayne, K. , Zhang, X. , Ramaswamy, V. , Jäger, N. , Jones, D. T. W. , Sill, M. , Pugh, T. J. , Ryzhova, M. , Wani, K. M. , Shih, D. J. H. , Head, R. & 69 others Remke, M., Bailey, S. D., Zichner, T., Faria, C. C., Barszczyk, M., Stark, S., Seker-Cin, H., Hutter, S., Johann, P., Bender, S., Hovestadt, V., Tzaridis, T., Dubuc, A. M., Northcott, P. A., Peacock, J., Bertrand, K. C., Agnihotri, S., Cavalli, F. M. G., Clarke, I., Nethery-Brokx, K., Creasy, C. L., Verma, S. K., Koster, J., Wu, X., Yao, Y., Milde, T., Sin-Chan, P., Zuccaro, J., Lau, L., Pereira, S., Castelo-Branco, P., Hirst, M., Marra, M. A., Roberts, S. S., Fults, D., Massimi, L., Cho, Y. J., Van Meter, T., Grajkowska, W., Lach, B., Kulozik, A. E., Von Deimling, A., Witt, O., Scherer, S. W., Fan, X., Muraszko, K. M., Kool, M., Pomeroy, S. L., Gupta, N., Phillips, J., Huang, A., Tabori, U., Hawkins, C., Malkin, D., Kongkham, P. N., Weiss, W. A., Jabado, N., Rutka, J. T., Bouffet, E., Korbel, J. O., Lupien, M., Aldape, K. D., Bader, G. D., Eils, R., Lichter, P., Dirks, P. B., Pfister, S. M., Korshunov, A. & Taylor, M. D. 2014 In : Nature. 506, 7489, p. 445-450 6 p.

Research output: Research - peer-reviewArticle

Ependymoma
Rhombencephalon
Epigenomics
CpG Islands
Methylation

Long residence time inhibition of EZH2 in activated polycomb repressive complex 2

Van Aller, G. S., Pappalardi, M. B., Ott, H. M., Diaz, E., Brandt, M., Schwartz, B. J., Miller, W. H., Dhanak, D., McCabe, M. T., Verma, S. K., Creasy, C. L., Tummino, P. J. & Kruger, R. G. Mar 21 2014 In : ACS Chemical Biology. 9, 3, p. 622-629 8 p.

Research output: Research - peer-reviewArticle

Polycomb Repressive Complex 2
GSK126
Histones
Chemical activation
Substrates