Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 7 Similar Profiles
Fibroblasts Medicine & Life Sciences
Telomerase Medicine & Life Sciences
Huntington Disease Medicine & Life Sciences
Cells Chemical Compounds
Cell Culture Techniques Medicine & Life Sciences
transglutaminase 2 Chemical Compounds
Embryonic Structures Medicine & Life Sciences
Transglutaminases Medicine & Life Sciences

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Research Output 1996 2017

Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease

Gomez-Pastor, R., Burchfiel, E. T., Neef, D. W., Jaeger, A. M., Cabiscol, E., McKinstry, S. U., Doss, A., Aballay, A., Lo, D. C., Akimov, S. S., Ross, C. A., Eroglu, C. & Thiele, D. J. Feb 13 2017 In : Nature Communications. 8, 14405

Research output: Research - peer-reviewArticle

Huntington Disease
Transcription Factors
heat shock transcription factor
Protective Factors
shock

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Lim, R. G. , Salazar, L. L. , Wilton, D. K. , King, A. R. , Stocksdale, J. T. , Sharifabad, D. , Lau, A. L. , Stevens, B. , Reidling, J. C. , Winokur, S. T. , Casale, M. S. , Thompson, L. M. , Pardo, M. , Díaz-Barriga, A. G. G. , Straccia, M. , Sanders, P. , Alberch, J. , Canals, J. M. , Kaye, J. A. , Dunlap, M. & 32 others Jo, L., May, H., Mount, E., Anderson-Bergman, C., Haston, K., Finkbeiner, S., Kedaigle, A. J., Gipson, T. A., Yildirim, F., Ng, C. W., Milani, P., Housman, D. E., Fraenkel, E., Allen, N. D., Kemp, P. J., Atwal, R. S., Biagioli, M., Gusella, J. F., MacDonald, M. E., Akimov, S. S., Arbez, N., Stewart, J., Ross, C. A., Mattis, V. B., Tom, C. M., Ornelas, L., Sahabian, A., Lenaeus, L., Mandefro, B., Sareen, D., Svendsen, C. N. & The HD iPSC Consortium May 1 2017 In : Nature Neuroscience. 20, 5, p. 648-660 13 p.

Research output: Research - peer-reviewArticle

Huntington Disease
Pharmacology
Genes
polyglutamine
Histone Code

PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically

Dickey, A. S. , Pineda, V. V. , Tsunemi, T. , Liu, P. P. , Miranda, H. C. , Gilmore-Hall, S. K. , Lomas, N. , Sampat, K. R. , Buttgereit, A. , Torres, M. J. M. , Flores, A. L. , Arreola, M. , Arbez, N. , Akimov, S. S. , Gaasterland, T. , Lazarowski, E. R. , Ross, C. A. , Yeo, G. W. , Sopher, B. L. , Magnuson, G. K. & 3 others Pinkerton, A. B., Masliah, E. & La Spada, A. R. Jan 1 2016 In : Nature Medicine. 22, 1, p. 37-45 9 p.

Research output: Research - peer-reviewArticle

PPAR delta
Huntington Disease
Neurons
Chemical activation
Transcriptional Activation

HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity

Mattis, V. B., Tom, C., Akimov, S., Saeedian, J., Østergaard, M. E., Southwell, A. L., Doty, C. N., Ornelas, L., Sahabian, A., Lenaeus, L., Mandefro, B., Sareen, D., Arjomand, J., Hayden, M. R., Ross, C. A. & Svendsen, C. N. Dec 15 2014 In : Human Molecular Genetics. 24, 11, p. 3257-3271 15 p., ddv080

Research output: Research - peer-reviewArticle

Induced Pluripotent Stem Cells
Huntington Disease
Brain-Derived Neurotrophic Factor
Glutamic Acid
Cell Line
Induced Pluripotent Stem Cells
Neurodegenerative Diseases
Phenotype
Therapeutics
Aptitude